Page last updated: 2024-09-04

vx 497 and pimozide

vx 497 has been researched along with pimozide in 1 studies

Compound Research Comparison

Studies
(vx 497)
Trials
(vx 497)
Recent Studies (post-2010)
(vx 497)
Studies
(pimozide)
Trials
(pimozide)
Recent Studies (post-2010) (pimozide)
25371,837143152

Protein Interaction Comparison

ProteinTaxonomyvx 497 (IC50)pimozide (IC50)
XBP1Homo sapiens (human)10
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.201
Ubiquitin carboxyl-terminal hydrolase 1Homo sapiens (human)2
Potassium channel subfamily K member 2Homo sapiens (human)1.8
Bile salt export pumpHomo sapiens (human)10
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)0.34
ATP-dependent translocase ABCB1Homo sapiens (human)2.2
Cytochrome P450 3A4Homo sapiens (human)9.7
DRattus norvegicus (Norway rat)0.0004
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0004
ATP-dependent translocase ABCB1Mus musculus (house mouse)4.9
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0004
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0004
Mu-type opioid receptorHomo sapiens (human)0.372
Sodium channel protein type 1 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 4 subunit alphaHomo sapiens (human)0.054
Delta-type opioid receptorHomo sapiens (human)3.76
Kappa-type opioid receptorHomo sapiens (human)0.99
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 7 subunit alphaHomo sapiens (human)0.054
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.201
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.152
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.201
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.201
Sodium channel protein type 5 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 9 subunit alphaHomo sapiens (human)0.054
WD repeat-containing protein 48Homo sapiens (human)2
Sodium channel protein type 2 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 3 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 11 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 8 subunit alphaHomo sapiens (human)0.054
Sodium channel protein type 10 subunit alphaHomo sapiens (human)0.054

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Agard, DA; Ashworth, A; Barrio-Hernandez, I; Batra, J; Beltrao, P; Bennett, MJ; Bohn, M; Bouhaddou, M; Braberg, H; Broadhurst, DJ; Cai, Y; Cakir, M; Calviello, L; Cavero, DA; Chang, JCJ; Chorba, JS; Craik, CS; d'Enfert, C; Dai, SA; Eckhardt, M; Emerman, M; Fabius, JM; Fletcher, SJ; Floor, SN; Foussard, H; Frankel, AD; Fraser, JS; Fujimori, DG; Ganesan, SJ; García-Sastre, A; Gordon, DE; Gross, JD; Guo, JZ; Haas, K; Haas, P; Hernandez-Armenta, C; Hiatt, J; Huang, XP; Hubert, M; Hüttenhain, R; Ideker, T; Jacobson, M; Jang, GM; Jura, N; Kaake, RM; Kim, M; Kirby, IT; Klippsten, S; Koh, C; Kortemme, T; Krogan, NJ; Kuzuoglu-Ozturk, D; Li, Q; Liboy-Lugo, J; Lin, Y; Liu, X; Liu, Y; Lou, K; Lyu, J; Mac Kain, A; Malik, HS; Mathy, CJP; McGregor, MJ; Melnyk, JE; Memon, D; Meyer, B; Miorin, L; Modak, M; Moreno, E; Mukherjee, S; Naing, ZZC; Noack, J; O'Meara, MJ; O'Neal, MC; Obernier, K; Ott, M; Peng, S; Perica, T; Pilla, KB; Polacco, BJ; Rakesh, R; Rathore, U; Rezelj, VV; Richards, AL; Roesch, F; Rosenberg, OS; Rosenthal, SB; Roth, BL; Roth, TL; Ruggero, D; Safari, M; Sali, A; Saltzberg, DJ; Savar, NS; Schwartz, O; Sharp, PP; Shen, W; Shengjuler, D; Shi, Y; Shoichet, BK; Shokat, KM; Soucheray, M; Stroud, RM; Subramanian, A; Swaney, DL; Taunton, J; Tran, QD; Trenker, R; Tummino, TA; Tutuncuoglu, B; Ugur, FS; Vallet, T; Venkataramanan, S; Verba, KA; Verdin, E; Vignuzzi, M; von Zastrow, M; Wang, HY; Wankowicz, SA; Wenzell, NA; White, KM; Xu, J; Young, JM; Zhang, Z; Zhou, Y1

Other Studies

1 other study(ies) available for vx 497 and pimozide

ArticleYear
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
    Nature, 2020, Volume: 583, Issue:7816

    Topics: Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Cloning, Molecular; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Evaluation, Preclinical; Drug Repositioning; HEK293 Cells; Host-Pathogen Interactions; Humans; Immunity, Innate; Mass Spectrometry; Molecular Targeted Therapy; Pandemics; Pneumonia, Viral; Protein Binding; Protein Biosynthesis; Protein Domains; Protein Interaction Mapping; Protein Interaction Maps; Receptors, sigma; SARS-CoV-2; SKP Cullin F-Box Protein Ligases; Vero Cells; Viral Proteins

2020