vx 497 has been researched along with bms-337197 in 3 studies
| Studies (vx 497) | Trials (vx 497) | Recent Studies (post-2010) (vx 497) | Studies (bms-337197) | Trials (bms-337197) | Recent Studies (post-2010) (bms-337197) |
|---|---|---|---|---|---|
| 25 | 3 | 7 | 6 | 0 | 0 |
| Protein | Taxonomy | vx 497 (IC50) | bms-337197 (IC50) |
|---|---|---|---|
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrish, JC; Bednarz, MS; Berry, KK; Chen, BC; Cheney, DL; Dhar, TG; Fleener, CA; Gu, HH; Guo, J; Harper, TW; Hollenbaugh, DL; Iwanowicz, EJ; Liu, C; MacMaster, JF; McIntyre, KW; Miller, LM; Pitts, WJ; Rouleau, KA; Shen, Z; Sherbina, NZ; Shuster, DJ; Tredup, JA; Watterson, SH; Witmer, MR; Zhao, R | 1 |
| Ballentine, SK; Barrish, JC; Chen, P; Dhar, TG; Fleener, CA; Gu, HH; Hollenbaugh, DL; Iwanowicz, EJ; Norris, D; Rouleau, KA; Shen, Z; Townsend, R; Watterson, SH | 1 |
| Beevers, RE; Buckley, GM; Davies, N; Fraser, JL; Galvin, FC; Hannah, DR; Haughan, AF; Jenkins, K; Mack, SR; Pitt, WR; Ratcliffe, AJ; Richard, MD; Sabin, V; Sharpe, A; Williams, SC | 1 |
3 other study(ies) available for vx 497 and bms-337197
| Article | Year |
|---|---|
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.
Topics: Animals; Antibody Formation; Arthritis, Experimental; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; IMP Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Morpholines; Mycophenolic Acid; Oxazoles; Rats; Rats, Inbred Lew; Structure-Activity Relationship | 2002 |
3-cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.
Topics: Catalysis; Enzyme Inhibitors; IMP Dehydrogenase; Indoles; Kinetics; Structure-Activity Relationship | 2003 |
Low molecular weight indole fragments as IMPDH inhibitors.
Topics: Carbamates; Crystallography, X-Ray; Enzyme Inhibitors; Hydrogen Bonding; IMP Dehydrogenase; Indoles; Models, Molecular; Molecular Structure; Molecular Weight; Oxazoles; Phenylurea Compounds; Sensitivity and Specificity; Structure-Activity Relationship | 2006 |