Page last updated: 2024-08-24

vorozole and androstenedione

vorozole has been researched along with androstenedione in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (66.67)18.2507
2000's9 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartz, U; Bayer, H; Grün, G; Hartmann, RW; Mitrenga, M; Sergejew, T1
Bowden, CR; Morris, DM; Tuman, RW; Wallace, NH1
De Coster, R; Janssen, PA; Krekels, MD; Leonaers, A; Van Ginckel, R; Wouters, W1
Bellens, D; Coene, MC; Janssen, PA; Lauwers, W; Le Jeune, L; Moereels, H; Roels, I; Vanden Bossche, H; Willemsens, G1
De Coster, R; Krekels, MD; Wouters, W1
Koymans, LM; Moereels, H; Vanden Bossche, H1
Balthazart, J; Foidart, A; Harada, N1
Casebolt, TL; Eto, I; Grubbs, CJ; Kelloff, GJ; Lubet, RA; Steele, VE1
Blankenstein, MA; de Frankrijker, E; Donker, TH; Nortier, HW; Thijssen, JH; van der Wall, E1
Callens, M; De Coster, R; Goeminne, N; Janssens, B; Van Ginckel, R; Wouters, L1
Dowsett, M1
Durgam, VR; Tekmal, RR1
Buzdar, AU; Roseman, BJ; Singletary, SE1
Harada, N; Hatano, O1
Blijham, GH; de Jong, PC1
Coombes, RC; Doody, D; Dowsett, M; English, J; Howes, A; Miall, S1
Bonneterre, J; Feutrie, ML1
Harvey, HA; Santen, RJ1
Bajetta, E; Bichisao, E; Pozzi, P; Toffolatti, L; Zilembo, N1
Auvray, P; Bichat, F; Genne, P1
de Crémoux, P1
Kerbrat, P; Lefeuvre, C1
Buzdar, A; Howell, A1
Bergström, M; Bergström-Pettermann, E; Bonasera, TA; Carlström, K; Holte, J; Kirilovas, D; Långström, B; Naessen, T; Simberg, N1
Bergström, M; Bergström-Petterman, E; Carlström, K; Kirilovas, D; Långström, B; Naessen, T1
Bria, E; Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Felici, A; Ferretti, G; Giannarelli, D; Milella, M; Mottolese, M; Nisticò, C; Papaldo, P; Ruggeri, EM; Terzoli, E1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP1

Reviews

11 review(s) available for vorozole and androstenedione

ArticleYear
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer.
    Journal of surgical oncology, 1997, Volume: 66, Issue:3

    Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles

1997
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women.
    The Netherlands journal of medicine, 1999, Volume: 55, Issue:2

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles

1999
[Aromatase inhibitors].
    Bulletin du cancer, 1999, Volume: 86, Issue:10

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles

1999
Use of aromatase inhibitors in breast carcinoma.
    Endocrine-related cancer, 1999, Volume: 6, Issue:1

    Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles

1999
Steroidal aromatase inhibitors in elderly patients.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:2

    Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles

2000
[Preclinical evaluation of aromatase inhibitors antitumor activity].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles

2000
[Aromatase inhibitors: pharmacological aspects].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles

2000
[Aromatase inhibitors: a review of clinical trials].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles

2000
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9

    Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting

2001
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles

2005
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
    Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18

    Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles

2006

Trials

2 trial(s) available for vorozole and androstenedione

ArticleYear
Inhibition of the in vivo conversion of androstenedione to estrone by the aromatase inhibitor vorozole in healthy postmenopausal women.
    Cancer research, 1993, Oct-01, Volume: 53, Issue:19

    Topics: Aged; Androstenedione; Aromatase Inhibitors; Carbon Radioisotopes; Double-Blind Method; Estrone; Female; Humans; Postmenopause; Triazoles; Tritium

1993
Vorozole results in greater oestrogen suppression than formestane in postmenopausal women and when added to goserelin in premenopausal women with advanced breast cancer.
    Breast cancer research and treatment, 1999, Volume: 56, Issue:1

    Topics: Adult; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Goserelin; Humans; Middle Aged; Ovary; Postmenopause; Premenopause; Triazoles

1999

Other Studies

14 other study(ies) available for vorozole and androstenedione

ArticleYear
Pyridyl-substituted tetrahydrocyclopropa[a]naphthalenes: highly active and selective inhibitors of P450 arom.
    Journal of medicinal chemistry, 1995, Jun-09, Volume: 38, Issue:12

    Topics: Adrenal Glands; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cattle; Female; Humans; Liver; Male; Mammary Neoplasms, Experimental; Naphthalenes; Ovary; Placenta; Pyridines; Rats; Testis

1995
Inhibition of peripheral aromatization in the male cynomolgus monkey by a novel nonsteroidal aromatase inhibitor (R 76713).
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Dose-Response Relationship, Drug; Estrone; Injections, Intravenous; Macaca fascicularis; Male; Pharmaceutical Vehicles; Triazoles

1991
Aromatase in the human choriocarcinoma JEG-3: inhibition by R 76 713 in cultured cells and in tumors grown in nude mice.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 38, Issue:4

    Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Binding, Competitive; Choriocarcinoma; Female; Humans; Kinetics; Mice; Mice, Nude; Substrate Specificity; Testosterone; Triazoles; Tumor Cells, Cultured

1991
R 76713 and enantiomers: selective, nonsteroidal inhibitors of the cytochrome P450-dependent oestrogen synthesis.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Adrenal Glands; Androgens; Androstenedione; Animals; Aromatase Inhibitors; Cattle; Cytochrome P-450 Enzyme Inhibitors; Estrogens; Female; Male; Microsomes; Placenta; Rabbits; Rats; Spectrophotometry; Stereoisomerism; Swine; Testis; Triazoles

1990
Aromatase inhibition by R 76 713: a kinetic analysis in rat ovarian homogenates.
    Steroids, 1990, Volume: 55, Issue:2

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Female; Kinetics; Ovary; Rats; Rats, Inbred Strains; Testosterone; Triazoles

1990
A molecular model for the interaction between vorozole and other non-steroidal inhibitors and human cytochrome P450 19 (P450 aromatase).
    The Journal of steroid biochemistry and molecular biology, 1995, Volume: 53, Issue:1-6

    Topics: Amino Acid Sequence; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Humans; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Triazoles

1995
Effects of steroidal and non steroidal aromatase inhibitors on sexual behavior and aromatase-immunoreactive cells and fibers in the quail brain.
    Brain research, 1994, Sep-19, Volume: 657, Issue:1-2

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Brain; Coturnix; Drug Implants; Immunoenzyme Techniques; Male; Nerve Fibers; Sexual Behavior, Animal; Testosterone; Triazoles

1994
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Aminoglutethimide; Androstenedione; Animals; Anticarcinogenic Agents; Aromatase Inhibitors; Drug Screening Assays, Antitumor; Estrus; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazoles

1994
Effects of combined and sequential treatment with tamoxifen and the aromatase inhibitor vorozole on 7,12-dimethylbenz(a) anthracene-induced mammary carcinoma in the rat.
    Cancer chemotherapy and pharmacology, 1996, Volume: 38, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Carcinogens; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Triazoles

1996
Aromatase inhibitors come of age.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:7

    Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles

1997
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
    Cancer letters, 1997, Sep-16, Volume: 118, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured

1997
Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:4

    Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Carcinoma, Hepatocellular; Choriocarcinoma; Colforsin; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Fadrozole; Humans; Liver Neoplasms; Neoplasm Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Triazoles; Tumor Cells, Cultured

1998
Effects of androgens on aromatase activity and 11C-vorozole binding in granulosa cells in vitro.
    Acta obstetricia et gynecologica Scandinavica, 2003, Volume: 82, Issue:3

    Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Binding, Competitive; Dihydrotestosterone; Enzyme Inhibitors; Etiocholanolone; Female; Granulosa Cells; Humans; Statistics, Nonparametric; Testosterone; Triazoles

2003
Characterization of [11C]vorozole binding in ovarian tissue in rats throughout estrous cycle in association with conversion of androgens to estrogens in vivo and in vitro.
    Steroids, 2003, Volume: 68, Issue:14

    Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Binding Sites; Enzyme Inhibitors; Estradiol; Estrous Cycle; Estrus; Female; In Vitro Techniques; Luteinizing Hormone; Ovary; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Triazoles

2003