voriconazole has been researched along with vt-1161 in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garvey, EP; Hoekstra, WJ; Moore, WR; Rafferty, SW; Schotzinger, RJ; Yates, CM | 1 |
| Garvey, EP; Hoekstra, WJ; Hull, CM; Kelly, DE; Kelly, SL; Moore, WR; Parker, JE; Schotzinger, RJ; Warrilow, AG | 1 |
| Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AGS; Wiederhold, NP | 1 |
3 other study(ies) available for voriconazole and vt-1161
| Article | Year |
|---|---|
Design and optimization of highly-selective fungal CYP51 inhibitors.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Conformation; Sterol 14-Demethylase; Structure-Activity Relationship | 2014 |
The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Binding Sites; Candida albicans; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Enzyme Assays; Escherichia coli; Fungal Proteins; Gene Expression; Humans; Protein Binding; Pyridines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Tetrazoles; Voriconazole | 2014 |
The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Substrate Specificity; Tetrazoles; Trichophyton; Voriconazole | 2017 |