Compounds > voriconazole
Page last updated: 2024-08-25

voriconazole and ergosterol

voriconazole has been researched along with ergosterol in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (13.64)29.6817
2010's17 (77.27)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Cannon, RD; Holmes, AR; Lamping, E; Nakamura, K; Niimi, K; Niimi, M; Ranchod, A; Tyndall, JD1
Han, XY; Hassan, SA; Matsuda, SP; May, GS; Tarrand, JJ; Wilson, WK; Xiong, Q1
Costa-de-Oliveira, S; Pina-Vaz, C; Pinto e Silva, AT; Rodrigues, AG; Silva-Dias, A1
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M1
Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, NJ; Warrilow, AG1
Blosser, SJ; Cramer, RA1
Alcazar-Fuoli, L; Bignell, E; Blatzer, M; Cairns, T; Grimalt, JO; Gründlinger, M; Haas, H; Lopez, JF; Puempel, T; Yasmin, S1
Kontoyiannis, DP; Lewis, RE; Lortholary, O; Roilides, E; Spellberg, B; Walsh, TJ1
Bader, O; Gross, U; Hull, CM; Kelly, DE; Kelly, SL; Parker, JE; Warrilow, AG; Weig, M1
Coste, A; Eddouzi, J; Ischer, F; Kelly, S; Manai, M; Parker, JE; Sanglard, D; Vale-Silva, LA1
Alencar, LP; Bandeira, TJPG; Brilhante, RSN; Cordeiro, RA; Evangelista, AJJ; Franco, JDS; Marques, FJF; Melo, CVS; Oliveira, JS; Rocha, MFG; Serpa, R; Sidrim, JJC1
Alencar, LP; Bandeira, SP; Bandeira, TJ; Brandine, GS; Brilhante, RS; Castelo-Branco, DS; Cordeiro, RA; Guedes, GM; Melo, LM; Moreira, JL; Paiva, MA; Pereira-Neto, WA; Ponte, YB; Rocha, MF; Sales, JA; Sidrim, JJ1
Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AG1
Fernandes, T; Henriques, M; Silva, S1
Long, N; Lu, L; Sang, H; Xu, X; Zeng, Q1
Albert, ND; Heo, ST; Jiang, Y; Jiménez-Ortigosa, C; Kontoyiannis, DP; Lewis, RE; Meis, JF; Mikos, AG; Perlin, DS; Tarrand, J; Tatara, AM; Tverdek, F; Verweij, PE1
Edrada-Ebel, R; Henriquez, FL; Rice, CA; Roberts, CW; Thomson, S; Zhang, T1
Geromanos, SJ; Hughes, CJ; Juvvadi, PR; Langridge, JI; Lennon, S; Moseley, MA; Perkins, SR; Richardson, K; Soderblom, EJ; Steinbach, WJ; Thompson, JW; Vissers, JPC; Wildgoose, J1
Keniya, MV; Monk, BC; Ruma, YN; Tyndall, JDA1
Deng, L; Li, W; Liu, H; Luo, T; Ren, B; Wu, J; Zhou, X; Zou, L1
Capilla, J; Guarro, J; López-Fernández, L; Martin-Vicente, A; Navarro-Rodríguez, P1
Castanheira, M; Collingsworth, TD; Davis, AP; Deshpande, LM; Pfaller, MA1

Other Studies

22 other study(ies) available for voriconazole and ergosterol

ArticleYear
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Blotting, Northern; Blotting, Southern; Candida; Candidiasis; Cell Membrane; Chromosomes, Fungal; Drug Resistance, Fungal; Endoplasmic Reticulum; Humans; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae

2009
Cholesterol import by Aspergillus fumigatus and its influence on antifungal potency of sterol biosynthesis inhibitors.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Cell Membrane; Cholesterol; Culture Media, Conditioned; Ergosterol; Humans; Itraconazole; Magnetic Resonance Spectroscopy; Oxygen Consumption; Pyrimidines; Spores, Fungal; Sterols; Triazoles; Voriconazole

2005
Dynamics of in vitro acquisition of resistance by Candida parapsilosis to different azoles.
    FEMS yeast research, 2009, Volume: 9, Issue:4

    Topics: Antifungal Agents; Biosynthetic Pathways; Candida; Drug Resistance, Fungal; Ergosterol; Fluconazole; Humans; Microbial Sensitivity Tests; Mutation; Pyrimidines; Triazoles; Voriconazole

2009
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole

2010
Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11

    Topics: Anti-Bacterial Agents; Aspergillus fumigatus; Azoles; Clotrimazole; Cytochrome P-450 Enzyme System; Doxycycline; Ergosterol; Fluconazole; Fungal Proteins; Genetic Complementation Test; Itraconazole; Pyrimidines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triazoles; Voriconazole

2010
SREBP-dependent triazole susceptibility in Aspergillus fumigatus is mediated through direct transcriptional regulation of erg11A (cyp51A).
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Genetic Complementation Test; Genotype; Humans; Microbial Sensitivity Tests; Organisms, Genetically Modified; Pyrimidines; Real-Time Polymerase Chain Reaction; Sterol Regulatory Element Binding Proteins; Transcription, Genetic; Triazoles; Voriconazole

2012
Mevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Feb-21, Volume: 109, Issue:8

    Topics: Amphotericin B; Animals; Aspergillus fumigatus; Biomass; Biosynthetic Pathways; Enoyl-CoA Hydratase; Ergosterol; Ferric Compounds; Gene Deletion; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Gene Silencing; Genes, Fungal; Hydroxamic Acids; Hydroxymethylglutaryl CoA Reductases; Iron Deficiencies; Ligases; Lovastatin; Mevalonic Acid; Mice; Microbial Sensitivity Tests; Oxidative Stress; Pulmonary Aspergillosis; Pyrimidines; Siderophores; Triazoles; Up-Regulation; Virulence; Voriconazole

2012
How does antifungal pharmacology differ for mucormycosis versus aspergillosis?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, Volume: 54 Suppl 1

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Cell Membrane; Cell Wall; Drug Resistance, Multiple, Fungal; Ergosterol; Gene Duplication; Genome, Fungal; Genomic Instability; Humans; Itraconazole; Microbial Sensitivity Tests; Mucormycosis; Pyrimidines; Rhizopus; Species Specificity; Triazoles; Virulence Factors; Voriconazole

2012
Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:8

    Topics: Amphotericin B; Antifungal Agents; Azoles; Base Sequence; Biological Transport; Candida glabrata; Drug Resistance, Multiple, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Humans; Microbial Sensitivity Tests; Mutation, Missense; Pyrimidines; Saccharomyces cerevisiae; Sequence Analysis, DNA; Sterol 14-Demethylase; Sterols; Triazoles; Voriconazole

2012
Molecular mechanisms of drug resistance in clinical Candida species isolated from Tunisian hospitals.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amphotericin B; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azoles; Base Sequence; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Polyenes; Pyrimidines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Analysis, DNA; Triazoles; Tunisia; Voriconazole

2013
Inhibition of heat-shock protein 90 enhances the susceptibility to antifungals and reduces the virulence of Cryptococcus neoformans/Cryptococcus gattii species complex.
    Microbiology (Reading, England), 2016, Volume: 162, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Biofilms; Caenorhabditis elegans; Cell Membrane; Cryptococcosis; Cryptococcus gattii; Cryptococcus neoformans; Ergosterol; Fluconazole; HSP90 Heat-Shock Proteins; Humans; Itraconazole; Melanins; Microbial Sensitivity Tests; Plankton; Voriconazole

2016
Cross-resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
    Mycoses, 2016, Volume: 59, Issue:5

    Topics: Animals; Anti-Allergic Agents; Antifungal Agents; ATP-Binding Cassette Transporters; Candida; Chlorobenzenes; Drug Resistance, Microbial; Ergosterol; Fluconazole; Fungicides, Industrial; Gene Expression Regulation, Fungal; Humans; Itraconazole; Malathion; Microbial Sensitivity Tests; Promethazine; Rhodamines; Sterol 14-Demethylase; Triazoles; Voriconazole

2016
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole

2016
Effect of Voriconazole on Candida tropicalis Biofilms: Relation with ERG Genes Expression.
    Mycopathologia, 2016, Volume: 181, Issue:9-10

    Topics: Antifungal Agents; Biofilms; Biosynthetic Pathways; Candida tropicalis; Drug Resistance, Fungal; Ergosterol; Gene Expression Profiling; Humans; Real-Time Polymerase Chain Reaction; Voriconazole

2016
Erg4A and Erg4B Are Required for Conidiation and Azole Resistance via Regulation of Ergosterol Biosynthesis in Aspergillus fumigatus.
    Applied and environmental microbiology, 2017, 02-15, Volume: 83, Issue:4

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Drug Resistance, Fungal; Ergosterol; Gene Deletion; Gene Expression Regulation, Fungal; Humans; Itraconazole; Mice; Microbial Sensitivity Tests; Oxidoreductases; Saccharomyces cerevisiae Proteins; Spores, Fungal; Voriconazole

2017
Changes in In Vitro Susceptibility Patterns of Aspergillus to Triazoles and Correlation With Aspergillosis Outcome in a Tertiary Care Cancer Center, 1999-2015.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017, Jul-15, Volume: 65, Issue:2

    Topics: Adult; Antifungal Agents; Aspergillosis; Aspergillus; Aspergillus fumigatus; Cohort Studies; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Ergosterol; Female; Fungal Proteins; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Invasive Pulmonary Aspergillosis; Male; Microbial Sensitivity Tests; Polymorphism, Genetic; Prospective Studies; Tertiary Healthcare; Treatment Outcome; Triazoles; Voriconazole; Young Adult

2017
Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba.
    Scientific reports, 2017, 08-15, Volume: 7, Issue:1

    Topics: 14-alpha Demethylase Inhibitors; Acanthamoeba; Antiprotozoal Agents; Azoles; Biosynthetic Pathways; Ergosterol; Molecular Structure; Parasitic Sensitivity Tests; Sterol 14-Demethylase; Sterols; Voriconazole

2017
Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.
    Journal of proteome research, 2018, 02-02, Volume: 17, Issue:2

    Topics: Antifungal Agents; Aspergillus fumigatus; Calcineurin; Caspofungin; Cell Membrane; Cell Wall; Chromatography, Liquid; Echinocandins; Ergosterol; Fungal Proteins; Gene Expression; Gene Ontology; Genes, Reporter; Green Fluorescent Proteins; Immunoprecipitation; Lipopeptides; Micafungin; Molecular Sequence Annotation; Protein Binding; Protein Interaction Mapping; Ribosomal Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Voriconazole

2018
Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11

    Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Candida glabrata; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Humans; Itraconazole; Lanosterol; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Sterol 14-Demethylase; Triazoles; Voriconazole

2018
Voriconazole inhibits cross-kingdom interactions between Candida albicans and Actinomyces viscosus through the ergosterol pathway.
    International journal of antimicrobial agents, 2019, Volume: 53, Issue:6

    Topics: Actinomyces viscosus; Animals; Antifungal Agents; Biofilms; Candida albicans; Ergosterol; Gentian Violet; Humans; In Situ Hybridization, Fluorescence; Metabolic Networks and Pathways; Microbial Interactions; Microbial Viability; Microscopy, Electron, Scanning; Provitamins; Staining and Labeling; Voriconazole

2019
    Antimicrobial agents and chemotherapy, 2020, 12-16, Volume: 65, Issue:1

    Topics: Antifungal Agents; Azoles; Candida albicans; Candida tropicalis; Candidiasis; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Humans; Microbial Sensitivity Tests; Permeability; Voriconazole

2020
Isavuconazole nonwildtype Aspergillus fumigatus isolates from a global surveillance study display alterations in multiple genes involved in the ergosterol biosynthesis pathway not previously associated with resistance to other azoles.
    Mycoses, 2021, Volume: 64, Issue:10

    Topics: Antifungal Agents; Aspergillus fumigatus; Azoles; Drug Resistance, Fungal; Ergosterol; Fungal Proteins; Humans; Itraconazole; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole; Whole Genome Sequencing

2021