vobasine has been researched along with tryptamine* in 1 studies
1 other study(ies) available for vobasine and tryptamine
| Article | Year |
|---|---|
Cytotoxic vobasine, tacaman, and corynanthe-tryptamine bisindole alkaloids from Tabernaemontana and structure revision of tronoharine.
Seven new indole alkaloids (1-7) comprising four vobasine, two tacaman, and one corynanthe-tryptamine bisindole alkaloid were isolated from the stem-bark extract of a Malayan Tabernaemontana. Two of the new vobasine alkaloids (1, 3), as well as 16-epivobasine (15) and 16-epivobasenal (17), showed appreciable cytotoxicity toward KB cells (IC50 ca. 5 μg/mL). The structure of the known Tabernaemontana alkaloid tronoharine (8) was revised based on newly acquired NMR data, as well as X-ray diffraction analysis. Topics: Antineoplastic Agents, Phytogenic; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Indole Alkaloids; Indoles; Malaysia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pausinystalia; Plants, Medicinal; Tabernaemontana; Tryptamines | 2014 |