Page last updated: 2024-08-25

voacamine and ibogaine

voacamine has been researched along with ibogaine in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (27.66)	18.7374
1990's	1 (2.13)	18.2507
2000's	10 (21.28)	29.6817
2010's	17 (36.17)	24.3611
2020's	6 (12.77)	2.80

Authors

Authors	Studies
Hesse, M; Morita, Y; Renner, U; Schmid, H	1
Jenks, CW	1
FISH, F; NEWCOMBE, F	1
Chen, HS; Du, JL; Jin, L; Jin, YS; Liang, S; Lu, J	1
Jung, HJ; Kim, Y; Kwon, HJ	1
Cromarty, AD; Pallant, CA; Steenkamp, V	1
Horie, S; Takayama, H; Terada, Y; Tominaga, M; Uchida, K; Watanabe, T	1
Horie, S; Kitajima, M; Taguchi, F; Takayama, H; Terada, Y; Watanabe, T	1
Alper, K; Bai, R; Fowler, SJ; Huang, XP; Liu, N; Priori, SG; Ruan, Y	1
Cao, ZX; Chen, HM; Dai, Y; Dan, XM; Deng, Y; Guo, DL; Hu, J; Li, HX; Mei, L; Song, CX; Yang, YT	1
Carreño, F; Dalla Costa, T; de Araújo, BV; de Miranda Silva, C; Grienke, U; Kratz, JM; Mair, CE; Rollinger, JM; Zimmermann, ES	1
Chávez Ávila, VM; Herrera Santoyo, J; Krengel, F; Olivera Flores, TJ; Pérez Flores, FJ; Reyes Chilpa, R	1
Krengel, F; Mijangos, MV; Reyes-Chilpa, R; Reyes-Lezama, M	1
Bussey, K; Caputi, L; Farrow, SC; Kamileen, MO; McAtee, RC; Mundy, JEA; O'Connor, SE; Stephenson, CRJ	1
Appelqvist, R; Cho, SM; Han, G; Kim, JY; Kim, TY; Kim, Y; Kwon, HJ; Lee, JY; Marko-Varga, G; Rezeli, M; Song, D; Sugihara, Y; Welinder, C; Yoo, JS	1
Carrera, I; González, B; Hernández, G; Seoane, G; Veiga, N	1
Cordell, GA; Farnsworth, NR; Kinghorn, AD; Ma, X; Mukherjee, R; Pezzuto, JM; You, M	1
Federici, E; Galeffi, C; Nicoletti, M; Palazzino, G; Ramanitrahasimbola, D; Rasoanaivo, P; Ratsimamanga-Urverg, S	1
Lépine, F; Milot, S; Morel, R; Zamir, L	1
Orellana, C	1
LA BARRE, J	5
GILLO, L; LA BARRE, J	1
BLANPIN, O; QUEVAUVILLER, A	3
DESMAREZ, JJ; LA BARRE, J	1
FISH, F; NEWCOMBE, F; POISSON, J	1
Wang, DY	1
Arancia, G; Calcabrini, A; Federici, E; Galeffi, C; Marra, M; Meschini, S	1
Arancia, G; Calcabrini, A; Cianfriglia, M; Condello, M; Dupuis, ML; Federici, E; Marra, M; Meschini, S	1
Arancia, G; Condello, M; Federici, E; Formisano, G; Marra, M; Meschini, S	1
Arancia, G; Calcabrini, A; Condello, M; De Milito, A; Federici, E; Formisano, G; Lista, P; Marra, M; Meschini, S	1
Deng, Y; Guo, DL; Li, F; Lu, CY; Mei, L	1
Arancia, G; Condello, M; Corinti, S; Cosentino, D; Di Felice, G; Gallo, FR; Meschini, S; Multari, G	1
Batista, MT; Chiruta, C; Costa, G; Currais, A; do Céu Madureira, M; Goujon-Svrzic, M; Maher, P; Paiva, J; Santos, T	1
Arancia, G; Condello, M; Gallo, FR; Meschini, S; Multari, G	1
Chowdhury, SR; De Macedo Silva, ST; De Souza, W; Dujardin, JC; Godinho, JLP; Kumar, A; Kumari, N; Majumder, HK; Mukhopadhyay, S; Rodrigues, JCF; Roy, S; Saha, S; Sundar, S; Zuma, AA	1
Deng, Y; Ding, WJ; Huai, WY; Li, HX; Liu, RQ; Liu, XC; Wang, YQ; Zhang, TE; Zhao, JS	1
Altieri, B; Condello, M; Galantini, L; Giansanti, L; Mancini, G; Meschini, S	1
Condello, M; Gallo, FR; Meschini, S; Multari, G; Pellegrini, E	1
Ansari, MN; Choudhary, A; Kaithwas, G; Kumar, D; Raj, R; Rastogi, S; Saeedan, AS; Singh, L; Singh, M	1
Condello, M; Gallo, FR; Meschini, S; Multari, G; Pellegrini, E; Vecchiotti, D; Zazzeroni, F	1
Chen, Y; Deng, Y; Huang, H; Huang, Y; Li, X; Lu, A; Lu, J; Pu, Y; Ren, Q; Shi, S; Xia, X; Yang, H; Yang, J; You, O; Zhang, C; Zuo, Y	1

Reviews

1 review(s) available for voacamine and ibogaine

Article	Year
Treatment of allergic rhinitis: H1-antihistamines and intranasal steroids. Current drug targets. Inflammation and allergy, 2002, Volume: 1, Issue:3 Topics: Administration, Intranasal; Adrenal Cortex Hormones; Drug Combinations; Histamine H1 Antagonists; Humans; Ibogaine; Receptors, Histamine H1; Rhinitis, Allergic, Seasonal; Steroids	2002

Other Studies

46 other study(ies) available for voacamine and ibogaine

Article	Year
[Transformation of the Iboga alkaloid voacangine into voaketone, a derivative of beta-carboline (author's transl)]. Helvetica chimica acta, 1976, Mar-10, Volume: 59, Issue:2 Topics: Alkaloids; Azepines; Chemical Phenomena; Chemistry; Ibogaine; Indoles	1976
Extraction studies of Tabernanthe iboga and Voacanga africana. Natural product letters, 2002, Volume: 16, Issue:1 Topics: Alkaloids; Bridged-Ring Compounds; Chromatography, Thin Layer; Ibogaine; Indole Alkaloids; Molecular Structure; Plant Bark; Plant Roots; Plants, Medicinal; Substance-Related Disorders; Tabernaemontana	2002
ALKALOIDS OF VOACANGA SCHWEINFURTHII STAPF: VOACORINE AND VOACANGINE. The Journal of pharmacy and pharmacology, 1964, Volume: 16 Topics: Alkaloids; Chemistry, Pharmaceutical; Chromatography; Ibogaine; Research; Voacanga	1964
[Study on chemical constituents in rhigome of Ervatamia hainanensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:13 Topics: Apocynaceae; Chromatography, Gel; Ibogaine; Oleanolic Acid; Plants, Medicinal; Rhizome	2007
A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo. Biochemical and biophysical research communications, 2012, Jan-06, Volume: 417, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Cell Proliferation; Chick Embryo; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Ibogaine; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Vascular Endothelial Growth Factor A	2012
Effect of an alkaloidal fraction of Tabernaemontana elegans (Stapf.) on selected micro-organisms. Journal of ethnopharmacology, 2012, Mar-27, Volume: 140, Issue:2 Topics: Anti-Bacterial Agents; Cell Line; Chromatography, Thin Layer; Fibroblasts; Gas Chromatography-Mass Spectrometry; Gram-Positive Bacteria; Hep G2 Cells; Humans; Ibogaine; Indole Alkaloids; Inhibitory Concentration 50; Lymphocytes; Macrophages; Microbial Sensitivity Tests; Mycobacterium; Plant Extracts; Plant Roots; Tabernaemontana	2012
Activation and inhibition of thermosensitive TRP channels by voacangine, an alkaloid present in Voacanga africana, an African tree. Journal of natural products, 2014, Feb-28, Volume: 77, Issue:2 Topics: Africa; Alkaloids; Calcium; Capsaicin; Humans; Ibogaine; Menthol; Molecular Structure; Plant Bark; Pyrimidinones; Transient Receptor Potential Channels; Trees; TRPV Cation Channels; Voacanga	2014
Identification of Indole Alkaloid Structural Units Important for Stimulus-Selective TRPM8 Inhibition: SAR Study of Naturally Occurring Iboga Derivatives. Journal of natural products, 2014, Aug-22, Volume: 77, Issue:8 Topics: Ibogaine; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Pyrazines; Pyridines; Structure-Activity Relationship; Tabernaemontana; TRPM Cation Channels	2014
hERG Blockade by Iboga Alkaloids. Cardiovascular toxicology, 2016, Volume: 16, Issue:1 Topics: Alkaloids; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Ibogaine; Patch-Clamp Techniques; Plant Extracts; Potassium Channel Blockers; Structure-Activity Relationship; Tabernaemontana	2016
Cytotoxic monoterpenoid indole alkaloids isolated from the barks of Voacanga africana Staph. Natural product research, 2016, Volume: 30, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Line, Tumor; Humans; Ibogaine; Indole Alkaloids; Molecular Structure; Plant Bark; Secologanin Tryptamine Alkaloids; Voacanga	2016
Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method. Planta medica, 2016, Volume: 82, Issue:11-12 Topics: Animals; Ether-A-Go-Go Potassium Channels; Humans; Ibogaine; Male; Molecular Structure; Rats; Rats, Wistar; Tandem Mass Spectrometry; Voacanga	2016
Quantification of Anti-Addictive Alkaloids Ibogaine and Voacangine in In Vivo- and In Vitro-Grown Plants of Two Mexican Tabernaemontana Species. Chemistry & biodiversity, 2016, Volume: 13, Issue:12 Topics: Ibogaine; Mexico; Species Specificity; Tabernaemontana	2016
Extraction and Conversion Studies of the Antiaddictive Alkaloids Coronaridine, Ibogamine, Voacangine, and Ibogaine from Two Mexican Tabernaemontana Species (Apocynaceae). Chemistry & biodiversity, 2019, Volume: 16, Issue:7 Topics: Bridged-Ring Compounds; Ibogaine; Mexico; Molecular Conformation; Plant Bark; Plant Roots; Species Specificity; Tabernaemontana	2019
Biosynthesis of an Anti-Addiction Agent from the Iboga Plant. Journal of the American Chemical Society, 2019, 08-21, Volume: 141, Issue:33 Topics: Biosynthetic Pathways; Humans; Ibogaine; Opioid-Related Disorders; Psychotropic Drugs; Stereoisomerism; Tabernaemontana	2019
Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI. Biomolecules, 2020, 03-27, Volume: 10, Issue:4 Topics: Animals; CD13 Antigens; Curcumin; Drug Evaluation, Preclinical; Female; Human Umbilical Vein Endothelial Cells; Humans; Ibogaine; Mass Spectrometry; Mice, Inbred BALB C; Molecular Docking Simulation; Tissue Distribution; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays	2020
Reactivity of the Iboga Skeleton: Oxidation Study of Ibogaine and Voacangine. Journal of natural products, 2023, Jun-23, Volume: 86, Issue:6 Topics: Ibogaine; Oxidation-Reduction; Skeleton; Tabernaemontana	2023
Indole alkaloids from Peschiera laeta that enhance vinblastine-mediated cytotoxicity with multidrug-resistant cells. Journal of natural products, 1994, Volume: 57, Issue:11 Topics: Alkaloids; Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Synergism; Humans; Ibogaine; KB Cells; Trees; Vinblastine	1994
Biological activities of the plant-derived bisindole voacamine with reference to malaria. Phytotherapy research : PTR, 2001, Volume: 15, Issue:1 Topics: Alkaloids; Animals; Antimalarials; Chloroquine; Drug Synergism; Ibogaine; Mice; Microbial Sensitivity Tests; Plasmodium falciparum; Plasmodium yoelii	2001
Liquid chromatographic/mass spectrometric determination of biologically active alkaloids in extracts of Peschiera fuschiaefolia. Journal of mass spectrometry : JMS, 2002, Volume: 37, Issue:2 Topics: Alkaloids; Antimalarials; Chromatography, High Pressure Liquid; Ibogaine; Medicine, Traditional; Plant Extracts; Reproducibility of Results; South America; Spectrometry, Mass, Electrospray Ionization; Tabernaemontana	2002
Doubts cast on antimalarial drug. The Lancet. Infectious diseases, 2003, Volume: 3, Issue:2 Topics: Africa; Antimalarials; Canada; Drug Approval; Drug Industry; Humans; Ibogaine; Plant Extracts	2003
[Enhancement of the cardiotonic effects of voacamine sulfate in the presence of aminophylline and heptaminol hydrochloride]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1955, Volume: 149, Issue:23-24 Topics: Alkaloids; Amino Alcohols; Aminophylline; Cardiac Glycosides; Cardiotonic Agents; Heptaminol; Humans; Ibogaine; Sulfates; Sulfur Oxides	1955
[Effect of voacamine sulfate on the fatigued heart]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Sep-26, Volume: 150, Issue:5 Topics: Alkaloids; Heart; Humans; Ibogaine; Sulfates	1956
[Voacamine camphosulfonate]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Nov-18, Volume: 150, Issue:6 Topics: Alkaloids; Humans; Ibogaine	1956
[Effects of voacamine sulfate on blood coagulation]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7 Topics: Alkaloids; Blood Coagulation; Humans; Ibogaine; Sulfates	1956
[Analgesic properties of voacamine]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7 Topics: Alkaloids; Analgesics; Ibogaine	1956
[Pharmacodynamic study of voacamine, an alkaloid of Voacanca africana, Apocynaceae]. Therapie, 1957, Volume: 12, Issue:4 Topics: Alkaloids; Apocynaceae; Humans; Ibogaine	1957
[Drugs increasing cardiotonic effects of vóacamine & voacaline]. Bulletin de l'Academie royale de medecine de Belgique, 1957, Volume: 22, Issue:6-7 Topics: Alkaloids; Camphor; Cardiotonic Agents; Humans; Ibogaine	1957
[Paralyzing effects of voacamine sulfate on the hypothalamic centers]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1957, Volume: 151, Issue:3 Topics: Alkaloids; Humans; Hypothalamus; Ibogaine; Sulfates	1957
[Pharmacodynamics in comparing voacamine & voacorine, alkaloids from Voacanga africana Stapi (Apocynaceae)]. Annales pharmaceutiques francaises, 1957, Volume: 15, Issue:11 Topics: Alkaloids; Apocynaceae; Ibogaine; Voacanga	1957
Alkaloids of Voacanga schweinfurthii Stapf. I. Voacamine and vobtusine. The Journal of pharmacy and pharmacology, 1960, Volume: 12(Suppl) Topics: Alkaloids; Ibogaine; Voacanga	1960
[Apropos of the reinforcing and bradycardiac effects of the strophanthin-voacamine combination]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154 Topics: Alkaloids; Bradycardia; Ibogaine; Reinforcement, Psychology; Strophanthins	1960
Voacamine, a bisindolic alkaloid from Peschiera fuchsiaefolia, enhances the cytotoxic effect of doxorubicin on multidrug-resistant tumor cells. International journal of oncology, 2003, Volume: 23, Issue:6 Topics: Alkaloids; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gentiana; Humans; Ibogaine; Microscopy, Confocal; Microscopy, Electron, Scanning; Plant Extracts	2003
Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells. International journal of oncology, 2005, Volume: 27, Issue:6 Topics: Alkaloids; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Ibogaine; Microscopy, Confocal; Microscopy, Electron, Scanning; Osteosarcoma; Plant Bark; Plant Extracts	2005
Autophagy-mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells. Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:2 Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Ibogaine; Microscopy, Electron, Scanning; Osteosarcoma; Protein Conformation	2007
The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells. Autophagy, 2008, Volume: 4, Issue:8 Topics: Antibiotics, Antineoplastic; Apoptosis; Autophagy; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescein-5-isothiocyanate; Humans; Ibogaine; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Osteosarcoma; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Vacuoles	2008
[Study on the alkaloids constituents from Voacanga africana]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2012, Volume: 35, Issue:2 Topics: Alkaloids; Ibogaine; Magnetic Resonance Spectroscopy; Plant Bark; Plant Roots; Plant Stems; Voacanga	2012
Voacamine modulates the sensitivity to doxorubicin of resistant osteosarcoma and melanoma cells and does not induce toxicity in normal fibroblasts. Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4 Topics: Alkaloids; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Bone Neoplasms; Cell Survival; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fibroblasts; Fluorescent Antibody Technique; Humans; Ibogaine; Melanoma; Molecular Structure; Osteosarcoma	2014
Screening and identification of neuroprotective compounds relevant to Alzheimer׳s disease from medicinal plants of S. Tomé e Príncipe. Journal of ethnopharmacology, 2014, Aug-08, Volume: 155, Issue:1 Topics: Alzheimer Disease; Animals; Atlantic Islands; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Ethnopharmacology; Humans; Ibogaine; Magnetic Resonance Spectroscopy; Medicine, African Traditional; Mice; Neuroprotective Agents; Plant Extracts; Plants, Medicinal; Rats; Spectrometry, Mass, Electrospray Ionization	2014
High-performance thin-layer chromatography for the evaluation of voacamine intracellular concentration related to its cytotoxic effect. Journal of pharmaceutical and biomedical analysis, 2015, Nov-10, Volume: 115 Topics: Antineoplastic Agents; Apoptosis; Biological Transport; Bone Neoplasms; Cell Line, Tumor; Cell Shape; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Ibogaine; Osteosarcoma; Reproducibility of Results	2015
Voacamine alters Leishmania ultrastructure and kills parasite by poisoning unusual bi-subunit topoisomerase IB. Biochemical pharmacology, 2017, 08-15, Volume: 138 Topics: Animals; Antiprotozoal Agents; Cell Shape; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Enzyme Stability; Female; Ibogaine; Leishmania donovani; Leishmania mexicana; Leishmaniasis, Visceral; Lethal Dose 50; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Plant Bark; Protein Subunits; Recombinant Proteins; Tabernaemontana; Topoisomerase I Inhibitors; Trypanosoma cruzi	2017
One bis-indole alkaloid-voacamine from Natural product research, 2019, Volume: 33, Issue:23 Topics: Alkaloids; Humans; Ibogaine; Indoles; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Surface Plasmon Resonance; Voacanga	2019
Influence of lipid composition on the ability of liposome loaded voacamine to improve the reversion of doxorubicin resistant osteosarcoma cells. Chemistry and physics of lipids, 2019, Volume: 223 Topics: Antibiotics, Antineoplastic; Bone Neoplasms; Cell Proliferation; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Ibogaine; Lipids; Liposomes; Molecular Conformation; Osteosarcoma; Particle Size; Surface Properties; Tumor Cells, Cultured	2019
Voacamine: Alkaloid with its essential dimeric units to reverse tumor multidrug resistance. Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 65 Topics: Antineoplastic Agents; Cell Line, Tumor; Dimerization; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Ibogaine; Microscopy, Confocal; Microtubules	2020
Effect of Voacamine upon inhibition of hypoxia induced fatty acid synthesis in a rat model of methyln-nitrosourea induced mammary gland carcinoma. BMC molecular and cell biology, 2021, Jun-05, Volume: 22, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Body Weight; Carcinoma; Computer Simulation; Electrocardiography; Fatty Acids; Female; Heart Rate; Hypoxia-Inducible Factor-Proline Dioxygenases; Ibogaine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metabolome; Methylnitrosourea; Neovascularization, Pathologic; Rats, Wistar; Tamoxifen	2021
A natural product, voacamine, sensitizes paclitaxel-resistant human ovarian cancer cells. Toxicology and applied pharmacology, 2022, 01-01, Volume: 434 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Ibogaine; Molecular Structure; Ovarian Neoplasms; Paclitaxel	2022
Voacamine is a novel inhibitor of EGFR exerting oncogenic activity against colorectal cancer through the mitochondrial pathway. Pharmacological research, 2022, Volume: 184 Topics: Adenosine Triphosphate; Animals; Apoptosis; bcl-2-Associated X Protein; Biological Products; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; ErbB Receptors; Ibogaine; Mice; Mitochondria; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases	2022