vitamin-k-1 and plastochromanol-8

vitamin-k-1 has been researched along with plastochromanol-8* in 2 studies

Other Studies

2 other study(ies) available for vitamin-k-1 and plastochromanol-8

Article	Year
A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis. Plant physiology, 2013, Volume: 162, Issue:2 In bacteria and mitochondria, ABC1 (for Activity of bc1 complex)-like kinases regulate ubiquinone synthesis, mutations causing severe respiration defects, including neurological disorders in humans. Little is known about plant ABC1-like kinases; in Arabidopsis (Arabidopsis thaliana), five are predicted in mitochondria but, surprisingly, six are located at lipid droplets in chloroplasts. These are a known site of prenylquinone (including tocopherol [vitamin E], phylloquinone [vitamin K] and plastoquinone) metabolism and contain a large proportion of the tocopherol cyclase (VTE1) required for vitamin E synthesis and recycling. Therefore, ABC1-like kinases may be involved in the regulation of chloroplast prenylquinone metabolism. Using a nontargeted lipidomics approach, we demonstrate that plants lacking the plastoglobule ABC1-like kinase ABC1K3 are defective both for the production of plastochromanol-8 (a plastoquinone-derived lipid antioxidant) and the redox recycling of α-tocopherol, whereas tocopherol production is not affected. All of these pathways require VTE1 activity. However, in the abc1k3 mutant, VTE1 levels are strongly reduced posttranscriptionally. We provide evidence that the ABC1-like kinase ABC1K3 phosphorylates VTE1, possibly stabilizing it at plastoglobules. However, ABC1K3 may also have other targets and be involved in a wider chloroplast regulatory network. Topics: alpha-Tocopherol; Arabidopsis; Arabidopsis Proteins; Chloroplasts; Chromans; Gene Expression Regulation, Plant; Intramolecular Transferases; Light; Molecular Sequence Data; Mutation; Phosphorylation; Plants, Genetically Modified; Protein Kinases; Vitamin E; Vitamin K 1	2013
Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-23, Volume: 108, Issue:34 Lipid droplets are ubiquitous cellular structures in eukaryotes and are required for lipid metabolism. Little is currently known about plant lipid droplets other than oil bodies. Here, we define dual roles for chloroplast lipid droplets (plastoglobules) in energy and prenylquinone metabolism. The prenylquinones--plastoquinone, plastochromanol-8, phylloquinone (vitamin K(1)), and tocopherol (vitamin E)--are partly stored in plastoglobules. This work shows that NAD(P)H dehydrogenase C1 (NDC1) (At5g08740), a type II NAD(P)H quinone oxidoreductase, associates with plastoglobules. NDC1 reduces a plastoquinone analog in vitro and affects the overall redox state of the total plastoquinone pool in vivo by reducing the plastoquinone reservoir of plastoglobules. Finally, NDC1 is required for normal plastochromanol-8 accumulation and is essential for vitamin K(1) production. Topics: Arabidopsis; Arabidopsis Proteins; Chloroplasts; Chromans; Gene Expression Regulation, Plant; Lipids; Luminescent Measurements; Mutation; NADH, NADPH Oxidoreductases; Photosynthesis; Plastoquinone; Protein Transport; Quinone Reductases; Quinones; Tocopherols; Vitamin E; Vitamin K 1	2011

Article

Year

A chloroplast ABC1-like kinase regulates vitamin E metabolism in Arabidopsis.

Plant physiology, 2013, Volume: 162, Issue:2

In bacteria and mitochondria, ABC1 (for Activity of bc1 complex)-like kinases regulate ubiquinone synthesis, mutations causing severe respiration defects, including neurological disorders in humans. Little is known about plant ABC1-like kinases; in Arabidopsis (Arabidopsis thaliana), five are predicted in mitochondria but, surprisingly, six are located at lipid droplets in chloroplasts. These are a known site of prenylquinone (including tocopherol [vitamin E], phylloquinone [vitamin K] and plastoquinone) metabolism and contain a large proportion of the tocopherol cyclase (VTE1) required for vitamin E synthesis and recycling. Therefore, ABC1-like kinases may be involved in the regulation of chloroplast prenylquinone metabolism. Using a nontargeted lipidomics approach, we demonstrate that plants lacking the plastoglobule ABC1-like kinase ABC1K3 are defective both for the production of plastochromanol-8 (a plastoquinone-derived lipid antioxidant) and the redox recycling of α-tocopherol, whereas tocopherol production is not affected. All of these pathways require VTE1 activity. However, in the abc1k3 mutant, VTE1 levels are strongly reduced posttranscriptionally. We provide evidence that the ABC1-like kinase ABC1K3 phosphorylates VTE1, possibly stabilizing it at plastoglobules. However, ABC1K3 may also have other targets and be involved in a wider chloroplast regulatory network.

Topics: alpha-Tocopherol; Arabidopsis; Arabidopsis Proteins; Chloroplasts; Chromans; Gene Expression Regulation, Plant; Intramolecular Transferases; Light; Molecular Sequence Data; Mutation; Phosphorylation; Plants, Genetically Modified; Protein Kinases; Vitamin E; Vitamin K 1

2013

Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation.

Proceedings of the National Academy of Sciences of the United States of America, 2011, Aug-23, Volume: 108, Issue:34

Lipid droplets are ubiquitous cellular structures in eukaryotes and are required for lipid metabolism. Little is currently known about plant lipid droplets other than oil bodies. Here, we define dual roles for chloroplast lipid droplets (plastoglobules) in energy and prenylquinone metabolism. The prenylquinones--plastoquinone, plastochromanol-8, phylloquinone (vitamin K(1)), and tocopherol (vitamin E)--are partly stored in plastoglobules. This work shows that NAD(P)H dehydrogenase C1 (NDC1) (At5g08740), a type II NAD(P)H quinone oxidoreductase, associates with plastoglobules. NDC1 reduces a plastoquinone analog in vitro and affects the overall redox state of the total plastoquinone pool in vivo by reducing the plastoquinone reservoir of plastoglobules. Finally, NDC1 is required for normal plastochromanol-8 accumulation and is essential for vitamin K(1) production.

Topics: Arabidopsis; Arabidopsis Proteins; Chloroplasts; Chromans; Gene Expression Regulation, Plant; Lipids; Luminescent Measurements; Mutation; NADH, NADPH Oxidoreductases; Photosynthesis; Plastoquinone; Protein Transport; Quinone Reductases; Quinones; Tocopherols; Vitamin E; Vitamin K 1

2011