vitamin-d-2 and pentosidine

vitamin-d-2 has been researched along with pentosidine* in 2 studies

Trials

2 trial(s) available for vitamin-d-2 and pentosidine

ArticleYear
Effect of Vitamin D Receptor Activation on the AGE/RAGE System and Myeloperoxidase in Chronic Kidney Disease Patients.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Aged; Arginine; Ergocalciferols; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Peroxidase; Receptor for Advanced Glycation End Products; Receptors, Calcitriol; Renal Insufficiency, Chronic; S100A12 Protein

2017
Active vitamin D treatment in CKD patients raises serum sclerostin and this effect is modified by circulating pentosidine levels.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:3

    1,25(OH). VDRA by paricalcitol causes a moderate increase in serum sclerostin in CKD patients. Such an effect is abolished by adjustment for PTH, suggesting that it may serve to counter PTH suppression. The sclerostin rise by PCT is attenuated by pentosidine, an observation in keeping with in vitro studies showing that AGEs alter the functioning of the VDRA.

    Topics: Adaptor Proteins, Signal Transducing; Aged; Arginine; Biomarkers; Bone Morphogenetic Proteins; Chronic Kidney Disease-Mineral and Bone Disorder; Double-Blind Method; Ergocalciferols; Female; Fibroblast Growth Factor-23; Genetic Markers; Humans; Italy; Lysine; Male; Middle Aged; Receptors, Calcitriol; Renal Insufficiency, Chronic; Time Factors; Treatment Outcome; Up-Regulation; Vitamins

2017