Page last updated: 2024-08-17

vinyl chloride and guanine

vinyl chloride has been researched along with guanine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19909 (40.91)18.7374
1990's6 (27.27)18.2507
2000's4 (18.18)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barbin, A; Bartsch, H; Ciroussel, F; Fedtke, N; Swenberg, JA1
Kuśmierek, JT; Mroczkowska, MM1
Cahill, DS; Cheng, KC; Dosanjh, MK; Loeb, LA; Preston, BD; Singer, B1
Chavez, F; Dosanjh, MK; Folkman, W; Kuśmierek, JT; Singer, B1
Boucheron, JA; Fedtke, N; Swenberg, JA; Turner, MJ1
Boucheron, JA; Fedtke, N; Swenberg, JA; Walker, VE1
Laib, RJ1
Fedtke, N; Swenberg, JA; Walker, VE1
Bartsch, H; Bolt, HM; Cartier, R; Laib, RJ1
Crane, AE; Davis, R; Smith, RJ; Watson, WP; Wright, AS1
Barbin, A; Bartsch, H1
Bar-Adon, R; Politzer, P; Zilles, BA1
Barbin, A; Bartsch, H; Laib, RJ1
Bolt, HM; Gwinner, LM; Laib, RJ1
Doerjer, G; Oesch, F1
Ham, A; Koc, H; Morinello, E; Ranasinghe, A; Swenberg, JA; Tretyakova, N; Upton, PB; Wu, K1
Ham, AJ; Morinello, EJ; Ranasinghe, A; Sangaiah, R; Swenberg, JA1
Koc, H; Morinello, EJ; Ranasinghe, A; Swenberg, JA1
Ham, AJ; Morinello, EJ; Nakamura, J; Ranasinghe, A; Swenberg, JA; Upton, PB1
Collins, LB; Daye, LR; Evansky, P; Hatch, G; Mutlu, E; Stout, MD; Swenberg, JA; Upton, PB; Winsett, D1
Collins, LB; Evansky, P; Ham, AJ; Hatch, G; Jeong, YC; Mutlu, E; Swenberg, JA; Upton, PB; Winsett, D1
Christov, PP; Egli, M; Guengerich, FP; Kozekov, ID; Pallan, PS; Pence, MG; Rizzo, CJ; Zhao, L1

Other Studies

22 other study(ies) available for vinyl chloride and guanine

ArticleYear
Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver.
    Carcinogenesis, 1992, Volume: 13, Issue:4

    Topics: Animals; Deoxyadenosines; DNA; Guanine; Liver; Mutation; Rats; Rats, Inbred Strains; Vinyl Chloride

1992
Miscoding potential of N2,3-ethenoguanine studied in an Escherichia coli DNA-dependent RNA polymerase in vitro system and possible role of this adduct in vinyl chloride-induced mutagenesis.
    Mutagenesis, 1991, Volume: 6, Issue:5

    Topics: DNA Damage; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Hydrogen Bonding; Magnesium; Manganese; Mutagenesis; Poly C; Vinyl Chloride

1991
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-15, Volume: 88, Issue:22

    Topics: Adenine; Base Composition; Base Sequence; DNA Polymerase II; DNA Replication; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Oligodeoxyribonucleotides; Uracil; Vinyl Chloride

1991
Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay.
    Carcinogenesis, 1991, Volume: 12, Issue:4

    Topics: Base Composition; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; DNA; Guanine; Guanosine; Kinetics; Mutagens; Phosphorus Radioisotopes; Polynucleotide 5'-Hydroxyl-Kinase; Thymidine; Vinyl Chloride

1991
Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: DNA; Gas Chromatography-Mass Spectrometry; Guanine; Vinyl Chloride; Vinyl Compounds

1990
Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Animals; DNA; Female; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds

1990
The role of cyclic base adducts in vinyl-chloride-induced carcinogenesis: studies on nucleic acid alkylation in vivo.
    IARC scientific publications, 1986, Issue:70

    Topics: Acetaldehyde; Adenine; Alkylation; Animals; Carcinogens; Cytosine; DNA; DNA Damage; Ethylene Oxide; Guanine; Microsomes, Liver; Rats; RNA; Vinyl Chloride; Vinyl Compounds

1986
Determination of 7-(2-oxoethyl)guanine and N2,3-ethenoguanine in DNA hydrolysates by HPLC.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; DNA Damage; Guanine; Guanosine; Hydrolysis; Rats; Rats, Inbred Strains; Vinyl Chloride

1989
Increased alkylation of liver DNA and cell turnover in young versus old rats exposed to vinyl chloride correlates with cancer susceptibility.
    Toxicology letters, 1989, Volume: 45, Issue:2-3

    Topics: Age Factors; Alkylation; Animals; Cell Division; DNA; Female; Guanine; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds

1989
A postlabelling assay for N7-(2-oxoethyl)guanine, the principal vinyl chloride-DNA adduct.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1987, Volume: 11

    Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA; Guanine; Vinyl Chloride

1987
Mutagenic and promutagenic properties of DNA adducts formed by vinyl chloride metabolites.
    IARC scientific publications, 1986, Issue:70

    Topics: Acetaldehyde; Adenine; Alkylating Agents; Animals; Carcinogens; Cytosine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Guanine; Mutagens; Vinyl Chloride; Vinyl Compounds

1986
The structure and properties of 7-(2-oxoethyl)guanine: a model for a key DNA alkylation product of vinyl chloride.
    IARC scientific publications, 1986, Issue:70

    Topics: DNA Damage; Guanine; Vinyl Chloride; Vinyl Compounds

1986
Lack of miscoding properties of 7-(2-oxoethyl)guanine, the major vinyl chloride-DNA adduct.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; DNA; DNA Replication; Ethylene Oxide; Guanine; Polydeoxyribonucleotides; Thymidine Monophosphate; Vinyl Chloride

1985
DNA alkylation by vinyl chloride metabolites: etheno derivatives or 7-alkylation of guanine?
    Chemico-biological interactions, 1981, Volume: 37, Issue:1-2

    Topics: Alkylation; Animals; Deoxyadenosines; Deoxycytidine; DNA; Guanine; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds

1981
Detection of N2,3-ethanoguanine in DNA after treatment with chloroacetaldehyde in vitro.
    Carcinogenesis, 1982, Volume: 3, Issue:6

    Topics: Acetaldehyde; Alkylation; Animals; DNA; Guanine; Salmon; Vinyl Chloride

1982
DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene.
    Mutation research, 2000, Jan-03, Volume: 464, Issue:1

    Topics: Animals; Butadienes; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Mice; Mice, Inbred Strains; Organ Specificity; Rats; Rats, Inbred Strains; Vinyl Chloride

2000
Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay.
    Chemical research in toxicology, 2001, Volume: 14, Issue:3

    Topics: Animals; Antibodies; Cell Transformation, Neoplastic; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Immunoassay; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Vinyl Chloride

2001
Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride.
    Cancer research, 2002, Sep-15, Volume: 62, Issue:18

    Topics: Administration, Inhalation; Age Factors; Animals; Brain; Carbon Isotopes; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Vinyl Chloride

2002
Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride.
    Cancer research, 2002, Sep-15, Volume: 62, Issue:18

    Topics: Administration, Inhalation; Age Factors; Animals; Carcinogens; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Hepatocytes; Liver; Male; Rats; Rats, Sprague-Dawley; Vinyl Chloride

2002
Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC.
    Chemical research in toxicology, 2010, Sep-20, Volume: 23, Issue:9

    Topics: Animals; Carbon Isotopes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Half-Life; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Vinyl Chloride

2010
A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats.
    Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2

    Topics: Animals; Brain; Chromatography, Liquid; DNA Adducts; Guanine; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Spleen; Tandem Mass Spectrometry; Testis; Vinyl Chloride

2012
Replication of N2,3-ethenoguanine by DNA polymerases.
    Angewandte Chemie (International ed. in English), 2012, May-29, Volume: 51, Issue:22

    Topics: DNA Adducts; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Mutation; Oxidative Stress; Protein Conformation; Vinyl Chloride

2012