vinyl chloride has been researched along with guanine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (40.91) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbin, A; Bartsch, H; Ciroussel, F; Fedtke, N; Swenberg, JA | 1 |
| Kuśmierek, JT; Mroczkowska, MM | 1 |
| Cahill, DS; Cheng, KC; Dosanjh, MK; Loeb, LA; Preston, BD; Singer, B | 1 |
| Chavez, F; Dosanjh, MK; Folkman, W; Kuśmierek, JT; Singer, B | 1 |
| Boucheron, JA; Fedtke, N; Swenberg, JA; Turner, MJ | 1 |
| Boucheron, JA; Fedtke, N; Swenberg, JA; Walker, VE | 1 |
| Laib, RJ | 1 |
| Fedtke, N; Swenberg, JA; Walker, VE | 1 |
| Bartsch, H; Bolt, HM; Cartier, R; Laib, RJ | 1 |
| Crane, AE; Davis, R; Smith, RJ; Watson, WP; Wright, AS | 1 |
| Barbin, A; Bartsch, H | 1 |
| Bar-Adon, R; Politzer, P; Zilles, BA | 1 |
| Barbin, A; Bartsch, H; Laib, RJ | 1 |
| Bolt, HM; Gwinner, LM; Laib, RJ | 1 |
| Doerjer, G; Oesch, F | 1 |
| Ham, A; Koc, H; Morinello, E; Ranasinghe, A; Swenberg, JA; Tretyakova, N; Upton, PB; Wu, K | 1 |
| Ham, AJ; Morinello, EJ; Ranasinghe, A; Sangaiah, R; Swenberg, JA | 1 |
| Koc, H; Morinello, EJ; Ranasinghe, A; Swenberg, JA | 1 |
| Ham, AJ; Morinello, EJ; Nakamura, J; Ranasinghe, A; Swenberg, JA; Upton, PB | 1 |
| Collins, LB; Daye, LR; Evansky, P; Hatch, G; Mutlu, E; Stout, MD; Swenberg, JA; Upton, PB; Winsett, D | 1 |
| Collins, LB; Evansky, P; Ham, AJ; Hatch, G; Jeong, YC; Mutlu, E; Swenberg, JA; Upton, PB; Winsett, D | 1 |
| Christov, PP; Egli, M; Guengerich, FP; Kozekov, ID; Pallan, PS; Pence, MG; Rizzo, CJ; Zhao, L | 1 |
22 other study(ies) available for vinyl chloride and guanine
| Article | Year |
|---|---|
Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver.
Topics: Animals; Deoxyadenosines; DNA; Guanine; Liver; Mutation; Rats; Rats, Inbred Strains; Vinyl Chloride | 1992 |
Miscoding potential of N2,3-ethenoguanine studied in an Escherichia coli DNA-dependent RNA polymerase in vitro system and possible role of this adduct in vinyl chloride-induced mutagenesis.
Topics: DNA Damage; DNA-Directed RNA Polymerases; Escherichia coli; Guanine; Hydrogen Bonding; Magnesium; Manganese; Mutagenesis; Poly C; Vinyl Chloride | 1991 |
The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli.
Topics: Adenine; Base Composition; Base Sequence; DNA Polymerase II; DNA Replication; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutagens; Oligodeoxyribonucleotides; Uracil; Vinyl Chloride | 1991 |
Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay.
Topics: Base Composition; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; DNA; Guanine; Guanosine; Kinetics; Mutagens; Phosphorus Radioisotopes; Polynucleotide 5'-Hydroxyl-Kinase; Thymidine; Vinyl Chloride | 1991 |
Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling.
Topics: DNA; Gas Chromatography-Mass Spectrometry; Guanine; Vinyl Chloride; Vinyl Compounds | 1990 |
Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA.
Topics: Animals; DNA; Female; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds | 1990 |
The role of cyclic base adducts in vinyl-chloride-induced carcinogenesis: studies on nucleic acid alkylation in vivo.
Topics: Acetaldehyde; Adenine; Alkylation; Animals; Carcinogens; Cytosine; DNA; DNA Damage; Ethylene Oxide; Guanine; Microsomes, Liver; Rats; RNA; Vinyl Chloride; Vinyl Compounds | 1986 |
Determination of 7-(2-oxoethyl)guanine and N2,3-ethenoguanine in DNA hydrolysates by HPLC.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; DNA Damage; Guanine; Guanosine; Hydrolysis; Rats; Rats, Inbred Strains; Vinyl Chloride | 1989 |
Increased alkylation of liver DNA and cell turnover in young versus old rats exposed to vinyl chloride correlates with cancer susceptibility.
Topics: Age Factors; Alkylation; Animals; Cell Division; DNA; Female; Guanine; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds | 1989 |
A postlabelling assay for N7-(2-oxoethyl)guanine, the principal vinyl chloride-DNA adduct.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA; Guanine; Vinyl Chloride | 1987 |
Mutagenic and promutagenic properties of DNA adducts formed by vinyl chloride metabolites.
Topics: Acetaldehyde; Adenine; Alkylating Agents; Animals; Carcinogens; Cytosine; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Escherichia coli; Ethylene Oxide; Guanine; Mutagens; Vinyl Chloride; Vinyl Compounds | 1986 |
The structure and properties of 7-(2-oxoethyl)guanine: a model for a key DNA alkylation product of vinyl chloride.
Topics: DNA Damage; Guanine; Vinyl Chloride; Vinyl Compounds | 1986 |
Lack of miscoding properties of 7-(2-oxoethyl)guanine, the major vinyl chloride-DNA adduct.
Topics: Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; DNA; DNA Replication; Ethylene Oxide; Guanine; Polydeoxyribonucleotides; Thymidine Monophosphate; Vinyl Chloride | 1985 |
DNA alkylation by vinyl chloride metabolites: etheno derivatives or 7-alkylation of guanine?
Topics: Alkylation; Animals; Deoxyadenosines; Deoxycytidine; DNA; Guanine; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds | 1981 |
Detection of N2,3-ethanoguanine in DNA after treatment with chloroacetaldehyde in vitro.
Topics: Acetaldehyde; Alkylation; Animals; DNA; Guanine; Salmon; Vinyl Chloride | 1982 |
DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene.
Topics: Animals; Butadienes; Carcinogens; DNA Adducts; Dose-Response Relationship, Drug; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Guanine; Mice; Mice, Inbred Strains; Organ Specificity; Rats; Rats, Inbred Strains; Vinyl Chloride | 2000 |
Simultaneous quantitation of N(2),3-ethenoguanine and 1,N(2)-ethenoguanine with an immunoaffinity/gas chromatography/high-resolution mass spectrometry assay.
Topics: Animals; Antibodies; Cell Transformation, Neoplastic; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Immunoassay; Male; Oxidation-Reduction; Rabbits; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Vinyl Chloride | 2001 |
Differential induction of N(2),3-ethenoguanine in rat brain and liver after exposure to vinyl chloride.
Topics: Administration, Inhalation; Age Factors; Animals; Brain; Carbon Isotopes; Carcinogens; DNA; DNA Adducts; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Liver; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Vinyl Chloride | 2002 |
Molecular dosimetry and repair of N(2),3-ethenoguanine in rats exposed to vinyl chloride.
Topics: Administration, Inhalation; Age Factors; Animals; Carcinogens; DNA Adducts; DNA Repair; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Guanine; Hepatocytes; Liver; Male; Rats; Rats, Sprague-Dawley; Vinyl Chloride | 2002 |
Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC.
Topics: Animals; Carbon Isotopes; Carcinogens; Chromatography, High Pressure Liquid; DNA Adducts; Guanine; Half-Life; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Vinyl Chloride | 2010 |
A new LC-MS/MS method for the quantification of endogenous and vinyl chloride-induced 7-(2-Oxoethyl)guanine in sprague-dawley rats.
Topics: Animals; Brain; Chromatography, Liquid; DNA Adducts; Guanine; Kidney; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Spleen; Tandem Mass Spectrometry; Testis; Vinyl Chloride | 2012 |
Replication of N2,3-ethenoguanine by DNA polymerases.
Topics: DNA Adducts; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Mutation; Oxidative Stress; Protein Conformation; Vinyl Chloride | 2012 |