Page last updated: 2024-08-23

vinyl carbamate and urethane

vinyl carbamate has been researched along with urethane in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19909 (13.85)18.7374
1990's18 (27.69)18.2507
2000's27 (41.54)29.6817
2010's10 (15.38)24.3611
2020's1 (1.54)2.80

Authors

AuthorsStudies
Marsden, AM; Orton, TC; Willets, JM; Wright, JA1
Leithauser, MT; Liem, A; Miller, EC; Miller, JA; Stewart, BC1
Wild, D1
Miller, JA; Park, KK; Stewart, BC; Surh, YJ1
Bolt, HM; Laib, RJ1
Allen, JW; Campbell, JA; Eppersimons, CF; Kligerman, AD; Petro, AB; Sharief, Y1
Allen, JW; Backer, LC; Campbell, JA; Hatch, GG; Nesnow, S; Pereira, MA; Sharief, Y; Stead, AG; Stoner, GD1
Conner, MK1
Allen, JW; Campbell, J; Langenbach, R; Leavitt, S; Sharief, Y1
Cheng, M; Conner, MK1
Allen, JW; Brock, K; Campbell, J; Langenbach, R; Leavitt, S; Nesnow, S; Sasseville, K; Sharief, Y1
Antoni, F; Csukás, I; Gungl, E; Solymosy, F; Vida, G1
Dahl, GA; Miller, EC; Miller, JA1
Lee, RC; Liem, A; Mayne, ST; Miller, JA; Park, KK; Surh, YJ1
Miller, JA; Park, KK; Surh, YJ1
Anderson, MW; Devereux, TR; Malarkey, DE; Maronpot, RR; Watson, MA1
Anderson, MW; Devereux, TR; Foley, JF; Maronpot, RR; Massey, TE1
Kadlubar, F; Sega, GA; Sotomayor, RE1
Beno, B; de Pascual-Teresa, B; Gouverneur, VE; Houk, KN; Janda, KD; Lerner, RA1
Liem, A; Miller, JA; Park, KK; Stewart, BC1
Ballering, LA; Nivard, MJ; Vogel, EW1
Hayashi, Y; Kodama, Y; Maronpot, RR; Mitsumori, K; Nomura, T; Wakana, S; Yamamoto, S; Yasuhara, K1
Kim, SG; Lee, JW; Liem, A; Miller, JA; Sohn, Y; Surh, YJ; Yoo, JK1
Kim, ND; Kim, SG; Lee, JM; Miller, JA; Park, KK; Sohn, Y; Surh, YJ1
Forkert, PG; Lee, RP1
Kim, SG; Miller, JA; Surh, YJ1
Nivard, MJ; Vogel, EW1
Forkert, PG; Titis, AP1
Forkert, PG; Lee, RP; Reid, K1
Gunning, WT; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE1
Al-Yaqoub, F; Gunning, WT; Kramer, PM; Li, Y; Lubet, RA; Pereira, MA; Steele, VE; Szabo, E; Tao, L1
Gunning, WT; Kramer, PM; Pereira, MA; Steele, VE1
Devereux, TR; Herzog, CR; Pittman, B; You, M1
Maruyama, C; Mitsumori, K; Ohnishi, Y; Suemizu, H; Tamaoki, N; Tomisawa, M; Urano, K; Usui, T; Yasuhara, K1
Barbin, A; Elder, RH; O'Connor, PJ; Wang, R1
Anderson, MW; Bodon, N; Devereux, TR; Herzog, CR; Maronpot, RR; Massey, TE; Pittman, B; You, M1
Bull, RJ; Lei, XC; Sasser, LB1
Belinsky, SA; Devereux, TR; Hutt, JA; Pulling, LC; Vuillemenot, BR1
Gunning, WT; Lubet, R; Pereira, MA; Tao, LH; Wang, W1
Lubet, RA; Wang, Y; You, M; Zhang, Z1
Jia, D; Lubet, RA; Wang, D; Wang, Y; Yao, R; You, M; Zhang, Z1
Alyaqoub, FS; Gunning, WT; Kramer, PM; Liu, Y; Lubet, RA; Nines, R; Pereira, MA; Steele, VE1
Alyaqoub, FS; Gunning, WT; Kramer, PM; Lubet, RA; Pereira, MA; Steele, VE; Tao, L1
Li, L; Liu, Y; Lubet, RA; Pereira, MA; Steele, VE; Tao, L1
Forkert, PG; Hernandez, LG3
Black, G; Bowers, R; Chen, H; Collins, K; Forkert, PG; Jones, G; Kaufmann, M; Sharma, A1
Li, L; Lubet, RA; Pereira, MA; Steele, VE; Tao, L1
Dmitrovsky, E; Gribble, GW; Honda, T; Liby, K; Risingsong, R; Royce, DB; Sporn, MB; Sporn, TA; Williams, CR; Yore, MM1
Alyaqoub, FS; Liu, Y; Lubet, RA; Pereira, MA; Steele, VE; Tao, L1
Dagousset, G; Liu, H; Masson, G; Retailleau, P; Zhu, J1
Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P1
Blake, DC; Grigoryeva, LS; Gundermann, EL; Herzog, CR; Mikse, OR1
Kassie, F; Melkamu, T; Tan, J; Zeng, Y; Zhang, X1
Liby, K; Ma, T; Risingsong, R; Royce, DB; Sporn, MB; Williams, CR; Yore, MM1
Forkert, PG1
James, M; Lu, Y; Lubet, RA; Szabo, E; Wang, Y; Wen, W; You, M1
Husár, B; Liska, R1
Casto, BC; Knobloch, TJ; Lubet, RA; Pereira, MA; Steele, VE; Warner, BM; Weghorst, CM1
Lubet, R; Pan, J; Wang, Y; You, M; Zhang, Q1
Du, RB; Lin, JH; Liu, S; Xiao, JC; Zong, G1
König, GM; Lohr, F; Mir Mohseni, M; Schäberle, TF; Schmitz, A1
Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B1
Chen, W; Cui, S; Hu, D; Li, Y; Qi, J1

Reviews

2 review(s) available for vinyl carbamate and urethane

ArticleYear
Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate.
    Drug metabolism reviews, 2010, Volume: 42, Issue:2

    Topics: Allyl Compounds; Animals; Carcinogens, Environmental; DNA Adducts; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Mutation; Sulfones; Urethane

2010
Vinyl carbonates, vinyl carbamates, and related monomers: synthesis, polymerization, and application.
    Chemical Society reviews, 2012, Mar-21, Volume: 41, Issue:6

    Topics: Carbonates; Cell Line; Cell Survival; Humans; Molecular Structure; Structure-Activity Relationship; Urethane

2012

Other Studies

63 other study(ies) available for vinyl carbamate and urethane

ArticleYear
Hepatocarcinogenic effect of vinyl carbamate in the C57Bl/10J strain mouse.
    Toxicologic pathology, 1991, Volume: 19, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Female; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Necrosis; Proto-Oncogenes; Time Factors; Urethane

1991
1,N6-ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate.
    Carcinogenesis, 1990, Volume: 11, Issue:3

    Topics: Adenosine; Animals; Ditiocarb; Epoxy Compounds; Ethers, Cyclic; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Microsomes, Liver; Mutagens; Neoplasms, Experimental; Polychlorinated Biphenyls; RNA; Sister Chromatid Exchange; Urethane

1990
Micronucleus induction in bone marrow by vinyl carbamate, a hypothetical metabolite of the carcinogen urethane (ethyl carbamate).
    Mutation research, 1991, Volume: 260, Issue:4

    Topics: Animals; Biotransformation; Bone Marrow; Bone Marrow Cells; Carcinogens; Mice; Micronucleus Tests; Mutagens; Urethane

1991
Synthesis and properties of vinyl carbamate epoxide, a possible ultimate electrophilic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate.
    Biochemical and biophysical research communications, 1990, Jun-29, Volume: 169, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Crystallography; Epoxy Compounds; Ethers, Cyclic; Mice; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Urethane; Water

1990
Vinyl acetate, a structural analog of vinyl carbamate, fails to induce enzyme-altered foci in rat liver.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: Adenosine Triphosphatases; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains; Urethane; Vinyl Compounds

1986
Sister chromatid exchange analysis in cultured primary lung, liver, and kidney cells of mice following in vivo exposure to vinyl carbamate.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1986, Volume: 22, Issue:8

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Kidney; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Rats; Sister Chromatid Exchange; Urethane

1986
Tumorigenesis and genotoxicity of ethyl carbamate and vinyl carbamate in rodent cells.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Animals; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Sex Factors; Sister Chromatid Exchange; Species Specificity; Urethane

1986
Induction of sister chromatid exchange by ethyl carbamate and vinyl carbamate.
    IARC scientific publications, 1986, Issue:70

    Topics: Animals; Cells, Cultured; DNA Damage; Lymphocytes; Macrophages; Mice; Sister Chromatid Exchange; Urethane

1986
Rodent species and strain specificities for sister-chromatid exchange induction and gene mutagenesis effects from ethyl carbamate, ethyl N-hydroxycarbamate, and vinyl carbamate.
    Mutation research, 1984, Volume: 126, Issue:2

    Topics: Animals; Bone Marrow; Carbamates; Cell Cycle; Cell Survival; Cricetinae; Crossing Over, Genetic; Hydroxamic Acids; Mice; Mutation; Rats; Sister Chromatid Exchange; Species Specificity; Structure-Activity Relationship; Urethane

1984
Comparison of sister chromatid exchange induction and known carcinogenic activities of vinyl and allyl carbamates.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Animals; Bone Marrow; Carbamates; Carcinogens; Crossing Over, Genetic; Liver; Liver Regeneration; Macrophages; Mice; Mice, Inbred Strains; Sister Chromatid Exchange; Structure-Activity Relationship; Urethane

1982
Comparative genotoxicity studies of ethyl carbamate and related chemicals: further support for vinyl carbamate as a proximate carcinogenic metabolite.
    Carcinogenesis, 1982, Volume: 3, Issue:12

    Topics: Animals; Biotransformation; Bone Marrow Cells; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Genes; Male; Mice; Mice, Inbred A; Sister Chromatid Exchange; Teratogens; Urethane

1982
Role of metabolic activation in the sister chromatid exchange-inducing activity of ethyl carbamate (urethane) and vinyl carbamate.
    Mutation research, 1981, Volume: 89, Issue:1

    Topics: Animals; Biotransformation; Cells, Cultured; Crossing Over, Genetic; Humans; Lymphocytes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Sister Chromatid Exchange; Urethane; Vinyl Compounds

1981
Comparative carcinogenicities and mutagenicities of vinyl carbamate, ethyl carbamate, and ethyl N-hydroxycarbamate.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: Adenoma; Animals; Caffeine; Carbamates; Ducks; Ear Neoplasms; Female; Hydroxamic Acids; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Mutagens; Neoplasms, Experimental; Rats; Urethane; Vinyl Compounds

1980
Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Capsaicin; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred ICR; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Skin Neoplasms; Sulfides; Urethane

1995
Chemoprotective properties of chlorophyllin against vinyl carbamate, p-nitrophenyl vinyl ether and their electrophilic epoxides.
    Cancer letters, 1995, Jul-20, Volume: 94, Issue:1

    Topics: Animals; Antimutagenic Agents; Chlorophyllides; DNA Adducts; Dose-Response Relationship, Drug; Epoxy Compounds; Female; Mice; Mice, Inbred ICR; Mutagenicity Tests; Papilloma; Salmonella typhimurium; Skin Neoplasms; Urethane; Vinyl Compounds

1995
H-ras oncogene mutation spectra in B6C3F1 and C57BL/6 mouse liver tumors provide evidence for TCDD promotion of spontaneous and vinyl carbamate-initiated liver cells.
    Carcinogenesis, 1995, Volume: 16, Issue:8

    Topics: Animals; Base Sequence; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Polychlorinated Dibenzodioxins; Urethane

1995
High frequency of K-ras mutations in spontaneous and vinyl carbamate-induced lung tumors of relatively resistant B6CF1 (C57BL/6J x BALB/cJ) mice.
    Carcinogenesis, 1995, Volume: 16, Issue:5

    Topics: Alleles; Animals; Base Sequence; Carcinogens; Codon; Crosses, Genetic; DNA Primers; Female; Genes, ras; Immunity, Innate; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Urethane

1995
Induction of DNA damage by urethane in mouse testes: DNA binding and unscheduled DNA synthesis.
    Environmental and molecular mutagenesis, 1994, Volume: 24, Issue:1

    Topics: Animals; DNA; DNA Damage; DNA Repair; DNA Replication; Male; Mice; Spermatogenesis; Spermatozoa; Testis; Urethane

1994
Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis.
    Science (New York, N.Y.), 1993, Oct-08, Volume: 262, Issue:5131

    Topics: Acrylamide; Acrylamides; Animals; Antibodies, Catalytic; Catalysis; Haptens; Mice; Models, Chemical; Molecular Conformation; Stereoisomerism; Thermodynamics; Urethane

1993
Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane).
    Carcinogenesis, 1993, Volume: 14, Issue:3

    Topics: Animals; Carcinogens; DNA; Female; Glutathione; Glutathione Transferase; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Urethane

1993
Preferential formation of deletions following in vivo exposure of postmeiotic Drosophila germ cells to the DNA etheno-adduct-forming carcinogen vinyl carbamate.
    Environmental and molecular mutagenesis, 1997, Volume: 30, Issue:3

    Topics: Animals; Carcinogens; Drosophila; Female; Follow-Up Studies; Gene Deletion; Genetic Markers; Germ Cells; Male; Mutagens; Urethane; Vinyl Chloride

1997
Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:3

    Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Body Weight; Carcinogens; Codon; Disease Susceptibility; Female; Genes, ras; Hemangiosarcoma; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Urethane

1997
Inhibition of vinyl carbamate-induced hepatotoxicity, mutagenicity, and tumorigenicity by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2- yl)carbamoyl]acetate (YH439).
    Carcinogenesis, 1998, Volume: 19, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cytochrome P-450 CYP2E1; Down-Regulation; Female; Liver; Liver Neoplasms, Experimental; Male; Mice; Rats; Rats, Sprague-Dawley; Thiazoles; Urethane

1998
Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide.
    Carcinogenesis, 1998, Volume: 19, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Inhibitors; Female; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred ICR; Mutagens; Pyrazines; Rats; Rats, Sprague-Dawley; Urethane

1998
Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:2

    Topics: Allyl Compounds; Animals; Antibodies, Monoclonal; Carboxylesterase; Carboxylic Ester Hydrolases; Carcinogens; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Female; Immunoblotting; In Vitro Techniques; Isoenzymes; Lung; Mice; Microsomes; Nitroso Compounds; Oxidoreductases, N-Demethylating; Phenylmethylsulfonyl Fluoride; Sulfones; Urethane

1999
Inhibitory effects of chlorophyllin on micronucleus formation induced by ethyl carbamate and its proximate and ultimate carcinogenic forms in mouse peripheral reticulocytes.
    Environmental and molecular mutagenesis, 1999, Volume: 34, Issue:1

    Topics: Animals; Antimutagenic Agents; Carcinogens; Chlorophyllides; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Micronuclei, Chromosome-Defective; Micronucleus Tests; Reticulocytes; Urethane

1999
Genetic effects of exocyclic DNA adducts in vivo: heritable genetic damage in comparison with loss of heterozygosity in somatic cells.
    IARC scientific publications, 1999, Issue:150

    Topics: Animals; Bone Marrow; Carmustine; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Eye Proteins; Female; Genotype; Insect Proteins; Loss of Heterozygosity; Male; Mutagens; Point Mutation; Recombination, Genetic; Tryptophan Oxygenase; Urethane

1999
Strain-related differences in bioactivation of vinyl carbamate and formation of DNA adducts in lungs of A/J, CD-1, and C57BL/6 mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 59, Issue:1

    Topics: Animals; Autoradiography; Carboxylesterase; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytochrome P-450 CYP2E1; DNA; DNA Adducts; Dose-Response Relationship, Drug; Female; Lung; Mice; Mice, Inbred C57BL; Microsomes; Phosphorus Radioisotopes; Species Specificity; Urethane

2001
Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:3

    Topics: Allyl Compounds; Antibodies, Monoclonal; Carboxylesterase; Carboxylic Ester Hydrolases; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Humans; Lung; Microsomes; NADP; Nitroso Compounds; Phenylmethylsulfonyl Fluoride; Sulfones; Urethane

2001
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethasone; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eflornithine; Female; Inositol; Lung Neoplasms; Mice; Mice, Inbred A; Phytotherapy; Piroxicam; Pulmonary Surfactants; Tea; Urethane

2000
Prevention of mouse lung tumors by budesonide and its modulation of biomarkers.
    Carcinogenesis, 2002, Volume: 23, Issue:7

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Budesonide; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Primers; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mice; Mice, Inbred A; Microfilament Proteins; Muscle Proteins; Polymerase Chain Reaction; RNA, Messenger; Urethane

2002
Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice.
    Cancer research, 2002, Aug-01, Volume: 62, Issue:15

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Female; Hydroxyurea; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Lung Neoplasms; Mice; Mice, Inbred A; Phenylcarbamates; Sulfonamides; Tosyl Compounds; Urethane

2002
Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Adenocarcinoma; Animals; Carcinogens; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C3H; Nitrosamines; Urethane

2002
Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice.
    Toxicology letters, 2003, Apr-30, Volume: 142, Issue:1-2

    Topics: Animals; Carcinogens; Codon; Crosses, Genetic; Female; Genes, ras; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; RNA, Neoplasm; Urethane

2003
Increased formation and persistence of 1,N(6)-ethenoadenine in DNA is not associated with higher susceptibility to carcinogenesis in alkylpurine-DNA-N-glycosylase knockout mice treated with vinyl carbamate.
    Cancer research, 2003, Nov-15, Volume: 63, Issue:22

    Topics: Animals; Apoptosis; Carcinogens; Cell Cycle; Cell Division; Deoxyadenosines; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Female; Hepatocytes; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Urethane

2003
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.
    Oncogene, 2004, Apr-15, Volume: 23, Issue:17

    Topics: Adenocarcinoma; Animals; Carcinogens; Chromosomal Instability; Chromosome Deletion; Chromosome Mapping; Crosses, Genetic; Ethylnitrosourea; Loss of Heterozygosity; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Urethane

2004
Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
    Toxicology, 2004, Jul-01, Volume: 199, Issue:2-3

    Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carcinogens; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Trichloroacetic Acid; Urethane; Water Supply

2004
Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens.
    Cancer research, 2004, Jun-01, Volume: 64, Issue:11

    Topics: Animals; Apoptosis Regulatory Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Line, Tumor; CpG Islands; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Hyperplasia; Lung; Lung Neoplasms; Methylene Chloride; Mice; Mice, Inbred A; Nitrosamines; Promoter Regions, Genetic; Smoking; Urethane

2004
Chemoprevention: mouse colon and lung tumor bioassay and modulation of DNA methylation as a biomarker.
    Experimental lung research, 2005, Volume: 31, Issue:2

    Topics: Animals; Azoxymethane; Biological Assay; Biomarkers; Budesonide; Carcinogens; Chemoprevention; Colonic Neoplasms; Dexamethasone; DNA Methylation; Dose-Response Relationship, Drug; Glucocorticoids; Insulin-Like Growth Factor II; Lung Neoplasms; Mice; Mice, Inbred Strains; Piroxicam; Urethane

2005
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
    Oncogene, 2006, Feb-23, Volume: 25, Issue:8

    Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Genes, ras; Heterozygote; Humans; Lung Neoplasms; Mice; Mice, Knockout; Mice, Transgenic; Tumor Suppressor Protein p53; Urethane

2006
Prevention of lung cancer progression by bexarotene in mouse models.
    Oncogene, 2006, Mar-02, Volume: 25, Issue:9

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Tetrahydronaphthalenes; Urethane

2006
Prevention of mouse lung tumors by targretin.
    International journal of cancer, 2006, May-01, Volume: 118, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Chemoprevention; Dose-Response Relationship, Drug; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Nitrosamines; Tetrahydronaphthalenes; Urethane

2006
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT).
    Carcinogenesis, 2007, Volume: 28, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Budesonide; Chemoprevention; Disease Models, Animal; DNA Methylation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Mice, Inbred A; Quinolones; Urethane

2007
Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors.
    International journal of cancer, 2007, Mar-01, Volume: 120, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers, Tumor; Body Weight; Budesonide; Caspase 3; Cell Proliferation; Cyclin B; Cyclin B2; Cyclin E; DNA Methylation; Female; Gene Expression; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Mice; Mice, Inbred Strains; Microtubule-Associated Proteins; Nitric Oxide Synthase Type II; Repressor Proteins; RNA, Messenger; RNA, Ribosomal, 18S; Survivin; Urethane

2007
In vivo mutagenicity of vinyl carbamate and ethyl carbamate in lung and small intestine of F1 (Big Blue x A/J) transgenic mice.
    International journal of cancer, 2007, Apr-01, Volume: 120, Issue:7

    Topics: Animals; Carcinogens; Colon; Female; Intestine, Small; Lung; Mice; Mice, Inbred A; Mice, Transgenic; Mutation; Polymerase Chain Reaction; Transcription Factors; Urethane; Viral Proteins

2007
Oxidation of vinyl carbamate and formation of 1,N6-ethenodeoxyadenosine in murine lung.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:5

    Topics: Adenosine; Administration, Oral; Alkylation; Allyl Compounds; Animals; Chromatography, Liquid; Cytochrome P-450 CYP2E1; Deoxyadenosines; DNA Damage; Dose-Response Relationship, Drug; Female; Lung; Mice; Microsomes; Molecular Structure; NADP; Oxidation-Reduction; Recombinant Proteins; Sulfones; Tandem Mass Spectrometry; Urethane

2007
Inhibition of vinyl carbamate-induced mutagenicity and clastogenicity by the garlic constituent diallyl sulfone in F1 (Big Blue x A/J) transgenic mice.
    Carcinogenesis, 2007, Volume: 28, Issue:8

    Topics: Allyl Compounds; Animals; Biotransformation; Crosses, Genetic; Cytochrome P-450 CYP2E1; DNA; Dose-Response Relationship, Drug; Female; Garlic; Intestine, Small; Lung; Male; Mice; Mice, Inbred A; Mice, Transgenic; Mutagens; Sulfones; Urethane

2007
Modulation by budesonide of a CpG endonuclease in mouse lung tumors.
    Carcinogenesis, 2007, Volume: 28, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Budesonide; CpG Islands; DNA Methylation; Endonucleases; Enzyme Activation; Female; Lung Neoplasms; Mice; Urethane

2007
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
    Cancer research, 2007, Mar-15, Volume: 67, Issue:6

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Oleanolic Acid; Phosphorylation; STAT3 Transcription Factor; Urethane

2007
Modulation by bexarotene of mRNA expression of genes in mouse lung tumors.
    Molecular carcinogenesis, 2008, Volume: 47, Issue:3

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Bexarotene; DNA Methyltransferase 3A; Drug Administration Schedule; Female; Gene Expression Regulation, Neoplastic; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Mice, Inbred A; Peptides; Pulmonary Surfactant-Associated Protein C; RNA, Messenger; Tetrahydronaphthalenes; Tumor Burden; Urethane; Uteroglobin

2008
Inhibition of vinyl carbamate-induced lung tumors and Kras2 mutations by the garlic derivative diallyl sulfone.
    Mutation research, 2009, Mar-09, Volume: 662, Issue:1-2

    Topics: Allyl Compounds; Amino Acid Substitution; Animals; Garlic; Lung Neoplasms; Mice; Mutation; Proto-Oncogene Proteins p21(ras); Sulfones; Urethane

2009
Chiral Brønsted acid-catalyzed enantioselective three-component Povarov reaction.
    Journal of the American Chemical Society, 2009, Apr-08, Volume: 131, Issue:13

    Topics: Aldehydes; Catalysis; Contractile Proteins; Phosphoric Acids; Quinolines; Stereoisomerism; Urethane

2009
Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Proliferation; Cyclooxygenase 2; Female; Indoles; Inositol; Lung Neoplasms; Mice; Mice, Inbred A; Poly(ADP-ribose) Polymerases; Urethane; Vitamin B Complex

2010
FoxO3a gene is a target of deletion in mouse lung adenocarcinoma.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Aflatoxin B1; Animals; Carcinogens; Disease Models, Animal; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Deletion; Loss of Heterozygosity; Lung Neoplasms; Mice; Nitrosamines; Polymerase Chain Reaction; Smoking; Urethane

2009
Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Blotting, Western; Female; Gene Expression Profiling; Indoles; Lung Neoplasms; Mice; Mice, Inbred A; MicroRNAs; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urethane

2010
Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:12

    Topics: Adenocarcinoma; Animals; Cell Proliferation; Fatty Acids, Unsaturated; Female; Ligands; Lung Neoplasms; Macrophages; Mice; Mice, Inbred A; Nicotinic Acids; Oleanolic Acid; Rats; Tetrahydronaphthalenes; Urethane

2009
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Chemoprevention; Cytoprotection; Drug Evaluation, Preclinical; Female; Humans; Lung Neoplasms; Mice; Mice, Transgenic; Pioglitazone; Thiazolidinediones; Tumor Cells, Cultured; Urethane

2010
Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.
    International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6

    Topics: Animals; Atorvastatin; Colonic Neoplasms; Dimethylhydrazines; Female; Heptanoic Acids; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Mice; Nitrosamines; Pyrroles; RNA, Messenger; Urethane; Vorinostat

2012
Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis.
    Molecular carcinogenesis, 2013, Volume: 52, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Benzo(a)pyrene; Betacyanins; Caspases; Cell Transformation, Neoplastic; Endothelium, Vascular; Female; Lung Neoplasms; Mice; Mice, Inbred A; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Poly(ADP-ribose) Polymerases; Random Allocation; Urethane

2013
The asymmetric synthesis of CF3- or -CF2-substituted tetrahydroquinolines by employing a chiral phosphoric acid as catalyst.
    Chemical communications (Cambridge, England), 2012, Aug-11, Volume: 48, Issue:62

    Topics: Catalysis; Hydrocarbons, Fluorinated; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphoric Acids; Quinolines; Stereoisomerism; Urethane

2012
Function of the loading module in CorI and of the O-methyltransferase CorH in vinyl carbamate biosynthesis of the antibiotic corallopyronin A.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Amino Acid Motifs; Anti-Bacterial Agents; Bacterial Proteins; Carbonic Acid; DNA-Directed RNA Polymerases; Escherichia coli; Esters; Gene Expression; Lactones; Methylation; Methyltransferases; Molecular Sequence Data; Myxococcales; Recombinant Proteins; Urethane

2014
A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response.
    Antioxidants & redox signaling, 2015, Sep-10, Volume: 23, Issue:8

    Topics: Acetone; Animals; Anticarcinogenic Agents; Arsenites; Benzyl Compounds; Carcinogenesis; Cell Line, Tumor; Curcumin; Epithelial Cells; Female; Humans; Lung Neoplasms; Mice; NF-E2-Related Factor 2; Sodium Compounds; Urethane

2015
Lysosomal Reacidification Ameliorates Vinyl Carbamate-Induced Toxicity and Disruption on Lysosomal pH.
    Journal of agricultural and food chemistry, 2020, Aug-19, Volume: 68, Issue:33

    Topics: Acids; Carcinogens; Cell Line; Cyclic AMP; Glutathione; Humans; Hydrogen-Ion Concentration; Lysosomes; Reactive Oxygen Species; Urethane

2020