vineomycin-b2 and olivose

vineomycin-b2 has been researched along with olivose* in 1 studies

Other Studies

1 other study(ies) available for vineomycin-b2 and olivose

ArticleYear
De novo asymmetric synthesis and biological evaluation of the trisaccharide portion of PI-080 and vineomycin B2.
    Organic letters, 2008, Oct-16, Volume: 10, Issue:20

    A highly enantio- and diastereoselective synthesis of an alpha-L-aculose, alpha-L-rhodinose, and beta-D-olivose trisaccharide is described. The key transformations include the palladium-catalyzed glycosylation, Myers' reductive rearrangement, diastereoselective dihydroxylation, and regioselective Mitsunobu inversion. Significant apoptotic antitumor activity was found for this trisaccharide, which has implication for vineomycin B2 and PI-080 structure-activity relationship.

    Topics: Anthraquinones; Cell Line, Tumor; Cell Survival; Deoxy Sugars; Humans; Molecular Structure; Stereoisomerism; Trisaccharides

2008