Page last updated: 2024-08-25

vindeburnol and vincamine

vindeburnol has been researched along with vincamine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.00)18.7374
1990's12 (42.86)18.2507
2000's5 (17.86)29.6817
2010's4 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belin, MF; Debure, LI; Fevre-Montange, M; Hardin, H; Moyse, E; Pujol, JF; Rousset, C; Weissmann, D1
Appel, M; Bertaux, O; Biou, D; Féger, J; Fournier, T; Porquet, D1
Bouilloux, JP; Pujol, JF; Richard, F; Zyzek, E1
Gillon, J; Labatut, R; Pujol, J; Richard, F; Weissmann, D1
Labatut, R; Lecestre, D; Milne, B; Pujol, JF; Quintin, L; Richard, F1
Bobillier, P; Broussolle, E; Darriet, D; Debilly, G; Pujol, JF1
Barzaghi, F; Dragonetti, M; Formento, ML; Gueniau, C; Mantegazza, P; Nencioni, A1
Foulhoux, P; Le Go, A; Patat, A1
Barzaghi, F; Boissier, JR; Dragonetti, M; Formento, ML1
Takeda, N; Wada, H; Watanabe, T; Yamatodani, A1
Bezin, L; Debure, LI; Ginovart, N; Pujol, JF; Rousset, C; Weissmann, D1
Garcia, C; Le Cavorsin, M; Marcel, D; Pujol, JF; Weissmann, D1
Bourde, O; Gillon, JY; Pujol, JF; Renaud, B; Vachette, C1
Bourde, O; Carbonnele, AC; Pujol, JF; Richard, F; Robert, F; Schmitt, P; Thal, C1
Bourde, O; Garcia, C; Pujol, JF; Reny-Palasse, V; Schmitt, P1
Bezin, L; Gagne, C; Garcia, C; Ginovart, N; Marcel, D; Pujol, JF; Weissmann, D1
Denoroy, L; Garcia, C; Le Cavorsin, M; Pujol, JF; Weissmann, D1
Bezin, L; Diaz, JJ; Le Cavorsin, M; Madjar, JJ; Marcel, D; Pujol, JF; Weissmann, D1
Bezin, L; Marcel, D; Pujol, JF; Raison, S; Weissmann, D1
Bezin, L; Blum, D; Garcia, C; Lafargue, P; Lellouche, JP; Marcel, D; Pujol, JF; Weissmann, D1
Bezin, L; Desgeorges, S; Marcel, D; Pujol, JF; Weissmann, D1
Caccamese, S; Din Belle, D; Jokela, R; Principato, G; Tolvanen, A1
Astier, B; Bezin, L; Lambas-Señas, L; Ogier, M; Ortemann, C; Pujol, JF; Renaud, B1
Gulyás, B; Vas, A1
Cambon, K; Carbon, A; Changeux, JP; Dos-Santos Coura, R; Granon, S; Groc, L; Pujol, JF; Weissmann, D1
Braun, D; Feinstein, DL; Kalinin, S; Lin, SX; Polak, PE; Sharp, A1
Argade, NP; Mondal, P1
Braun, D; Feinstein, DL1

Reviews

1 review(s) available for vindeburnol and vincamine

ArticleYear
Eburnamine derivatives and the brain.
    Medicinal research reviews, 2005, Volume: 25, Issue:6

    Topics: Animals; Apocynaceae; Brain; Humans; Nucleotides, Cyclic; Positron-Emission Tomography; Receptors, GABA-A; Sodium Channel Blockers; Vinca Alkaloids; Vincamine

2005

Trials

1 trial(s) available for vindeburnol and vincamine

ArticleYear
Dose-response relationship of vindeburnol based on spectral analysis of posturographic recordings.
    European journal of clinical pharmacology, 1985, Volume: 29, Issue:4

    Topics: Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Postural Balance; Posture; Random Allocation; Vinca Alkaloids; Vincamine

1985

Other Studies

26 other study(ies) available for vindeburnol and vincamine

ArticleYear
Somatotopic organization of tyrosine hydroxylase expression in the rat locus coeruleus: long term effect of RU24722.
    Brain research, 1992, May-22, Volume: 581, Issue:1

    Topics: Animals; Autoradiography; Brain Mapping; Calibration; Cell Count; Efferent Pathways; Immunohistochemistry; Injections, Intraperitoneal; Locus Coeruleus; Male; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase; Vincamine

1992
Evaluation of the hepatotoxicological effects of a drug in an in vivo/in vitro model.
    Experientia, 1992, Mar-15, Volume: 48, Issue:3

    Topics: Animals; Blood; Blotting, Northern; Evaluation Studies as Topic; Liver; Male; Orosomucoid; Rats; Rats, Inbred Strains; RNA; Toxicology; Vincamine

1992
Ontogeny of tyrosine hydroxylase concentration in locus coeruleus of newborn rats: long-term effects of RU24722.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: Aging; Animals; Enzyme Induction; Locus Coeruleus; Male; Rats; Rats, Inbred Strains; Tyrosine 3-Monooxygenase; Vinca Alkaloids; Vincamine

1990
[Measurement of brain tyrosine hydroxylase concentrations by quantitative autoradiography after transfer of soluble proteins to nitro-cellulose].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1988, Volume: 306, Issue:14

    Topics: Animals; Autoradiography; Brain; Immunohistochemistry; Male; Rats; Staining and Labeling; Tyrosine 3-Monooxygenase; Vincamine

1988
Long-term effects of RU24722 on tyrosine hydroxylase of the rat brain.
    Journal of neurochemistry, 1988, Volume: 51, Issue:5

    Topics: Animals; Brain; Clonidine; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Locus Coeruleus; Male; Neurons; Piperoxan; Rats; Rats, Inbred Strains; Substantia Nigra; Tegmentum Mesencephali; Tyrosine 3-Monooxygenase; Vinca Alkaloids; Vincamine

1988
RU 24722, a new eburnamine derivative, induces selective alterations in cerebral glucose utilization in freely moving rat.
    European journal of pharmacology, 1989, Jan-17, Volume: 159, Issue:3

    Topics: Animals; Behavior, Animal; Cerebral Cortex; Glucose; Male; Rats; Rats, Inbred Strains; Vinca Alkaloids; Vincamine

1989
A comparison of some of the pharmacological properties of the new eburnamenine derivative vindeburnol with those of vincamine, vinburnine, dihydroergotoxine mesilate and nicergoline.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:10

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders; Dihydroergotoxine; Electroencephalography; Ergolines; Gerbillinae; Male; Mice; Mice, Inbred Strains; Nicergoline; Rats; Rats, Inbred Strains; Vinca Alkaloids; Vincamine

1986
Effects of the new eburnamenine derivative RU 24722 on EEG recovery and cerebral energy metabolism after complete ischemia.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Dihydroergotoxine; Electroencephalography; Energy Metabolism; Glucose; Glycogen; Lactates; Lactic Acid; Male; Mice; Nicergoline; Phosphocreatine; Rats; Vasodilator Agents; Vinca Alkaloids; Vincamine

1985
Effect of a new eburnamine derivative, RU 24722, on the turnover of monoamines in mouse brain: selective and reversible decrease of noradrenaline.
    European journal of pharmacology, 1984, Nov-13, Volume: 106, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred Strains; Norepinephrine; Time Factors; Vinca Alkaloids; Vincamine

1984
RU24722 induces spatially organized phenotypic plasticity in the locus coeruleus.
    Neuroreport, 1994, Sep-08, Volume: 5, Issue:14

    Topics: Animals; Fenclonine; Locus Coeruleus; Male; Neuronal Plasticity; Phenotype; Rats; Rats, Inbred Strains; Reserpine; Tyrosine 3-Monooxygenase; Vincamine

1994
Phenotypic characteristics of expressed tyrosine hydroxylase protein in the adult rat nucleus tractus solitarius: plasticity revealed by RU24722 treatment.
    Neuroscience, 1994, Volume: 62, Issue:4

    Topics: Animals; Autoradiography; Immunohistochemistry; Immunologic Techniques; Male; Medulla Oblongata; Neuronal Plasticity; Neurons; Phenotype; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase; Vincamine

1994
Decrease in the reactivity of locus coeruleus neurons to hypotension after an increase in their tyrosine hydroxylase content: a subregional in vivo voltammetry study in the rat.
    The European journal of neuroscience, 1993, Mar-01, Volume: 5, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acid-Base Equilibrium; Animals; Catechols; Electric Conductivity; Electrochemistry; Hemodynamics; Hypotension; Locus Coeruleus; Male; Neurons; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Vincamine

1993
Long-term effect of RU24722 on tyrosine hydroxylase in the rat locus coeruleus: differential effects of two enantiomeric forms.
    Neurochemistry international, 1993, Volume: 23, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Locus Coeruleus; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Vincamine

1993
Further characterization of the long-term effect of RU24722 on tyrosine hydroxylase in the rat locus coeruleus.
    Journal of neurochemistry, 1993, Volume: 61, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Animals; Hypophysectomy; Locus Coeruleus; Male; Orchiectomy; Rats; Rats, Sprague-Dawley; Substantia Nigra; Thyroidectomy; Time Factors; Tissue Distribution; Tyrosine 3-Monooxygenase; Vincamine

1993
Tyrosine hydroxylase expression within Balb/C and C57black/6 mouse locus coeruleus. I. Topological organization and phenotypic plasticity of the enzyme-containing cell population.
    Brain research, 1996, May-20, Volume: 721, Issue:1-2

    Topics: Animals; Autoradiography; Immunohistochemistry; Locus Coeruleus; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuronal Plasticity; Neurons; Perfusion; Phenotype; Species Specificity; Tyrosine 3-Monooxygenase; Vincamine

1996
Pharmacological modulations of adrenergic phenotype in medullary C2 and C3 cell groups of adult rat.
    Journal of chemical neuroanatomy, 1996, Volume: 11, Issue:2

    Topics: Analysis of Variance; Animals; Drug Evaluation, Preclinical; Immunohistochemistry; Male; Medulla Oblongata; Neurons; Phenotype; Phenylethanolamine N-Methyltransferase; Rats; Rats, Sprague-Dawley; Reference Values; Sympathetic Nervous System; Tyrosine 3-Monooxygenase; Vincamine

1996
Controlled targeting of tyrosine hydroxylase protein toward processes of locus coeruleus neurons during postnatal development.
    Brain research. Molecular brain research, 1997, Oct-15, Volume: 50, Issue:1-2

    Topics: Analysis of Variance; Animals; Image Processing, Computer-Assisted; Immunohistochemistry; In Situ Hybridization; Locus Coeruleus; Male; Neuronal Plasticity; Neurons; Rats; Tyrosine 3-Monooxygenase; Vincamine

1997
Plasticity of tyrosine hydroxylase gene expression within BALB/C and C57Black/6 mouse locus coeruleus.
    Neuroscience letters, 1998, Feb-13, Volume: 242, Issue:2

    Topics: Animals; Catecholamines; Gene Expression Regulation, Enzymologic; In Situ Hybridization; Locus Coeruleus; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuronal Plasticity; Phenotype; RNA, Messenger; Transcription, Genetic; Tyrosine 3-Monooxygenase; Vincamine

1998
In situ examination of tyrosine hydroxylase activity in the rat locus coeruleus using (3',5')-[(3)H(2)]-alpha-fluoromethyl-tyrosine as substrate of the enzyme.
    Synapse (New York, N.Y.), 2000, Mar-01, Volume: 35, Issue:3

    Topics: Animals; Fluorine Radioisotopes; In Situ Hybridization; Locus Coeruleus; Rats; Rats, Sprague-Dawley; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase; Vincamine

2000
Singular subsets of locus coeruleus neurons may recover tyrosine hydroxylase phenotype transiently expressed during development.
    Brain research. Molecular brain research, 2000, Mar-29, Volume: 76, Issue:2

    Topics: Aging; Animals; Apoptosis; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Image Processing, Computer-Assisted; In Situ Hybridization; Locus Coeruleus; Male; Neurons; Phenotype; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Tyrosine 3-Monooxygenase; Vincamine

2000
Chiral HPLC separation and CD spectra of the enantiomers of the alkaloid tacamonine and related compounds.
    Chirality, 2001, Volume: 13, Issue:10

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Indole Alkaloids; Molecular Structure; Stereoisomerism; Vincamine

2001
Enhanced tail pinch-induced activation of catecholamine metabolism in the pericerulean area of RU 24722-treated rats.
    Brain research, 2004, Dec-24, Volume: 1030, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Microdialysis; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tail; Tyrosine 3-Monooxygenase; Vincamine

2004
Aggressive behavior during social interaction in mice is controlled by the modulation of tyrosine hydroxylase expression in the prefrontal cortex.
    Neuroscience, 2010, Dec-15, Volume: 171, Issue:3

    Topics: Aggression; Animals; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Norepinephrine; Prefrontal Cortex; Social Behavior; Tyrosine 3-Monooxygenase; Vincamine

2010
The vincamine derivative vindeburnol provides benefit in a mouse model of multiple sclerosis: effects on the Locus coeruleus.
    Journal of neurochemistry, 2012, Volume: 121, Issue:2

    Topics: Animals; Cerebellum; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Indicators and Reagents; Locus Coeruleus; Macrophage Activation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin Proteins; Myelin-Oligodendrocyte Glycoprotein; Neuroglia; Norepinephrine; RNA, Messenger; Survival; T-Lymphocytes; Tyrosine 3-Monooxygenase; Vincamine

2012
Stereoselective synthesis of (-)-desethyleburnamonine, (-)-vindeburnol and (-)-3-epitacamonine: observation of a substrate dependent diastereoselectivity reversal of an aldol reaction.
    Organic & biomolecular chemistry, 2016, Nov-08, Volume: 14, Issue:44

    Topics: Chemistry Techniques, Synthetic; Indole Alkaloids; Ketones; Stereoisomerism; Vincamine

2016
The locus coeruleus neuroprotective drug vindeburnol normalizes behavior in the 5xFAD transgenic mouse model of Alzheimer's disease.
    Brain research, 2019, 01-01, Volume: 1702

    Topics: Adrenergic Neurons; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Disease Progression; Hippocampus; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Neurons; Neuroprotective Agents; Norepinephrine; Phosphodiesterase I; Vincamine

2019