vinblastine has been researched along with vincristine in 41 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (7.32) | 18.7374 |
1990's | 8 (19.51) | 18.2507 |
2000's | 17 (41.46) | 29.6817 |
2010's | 13 (31.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Boutin, JA; Cudennec, CA; Hautefaye, P; Lavielle, G; Pierré, A; Schaeffer, C | 1 |
Ishikawa, T; Keppler, D; Klünemann, C; Müller, M; Schaub, T | 1 |
Hansch, C; Khwaja, TA; Selassie, CD | 1 |
Duffel, MW; Elmarakby, SA; Rosazza, JP | 1 |
Duffel, MW; Elmarakby, SA; Goswami, A; Rosazza, JP; Sariaslani, FS | 1 |
Atassi, G; Bhushana Rao, KS; Collard, MP; Dejonghe, JP; Hannart, JA; Trouet, A | 1 |
Chai, H; Cruz, JG; Hernández, L; Mar, W; Novelo, M; Pereda-Miranda, R; Pezzuto, JM | 1 |
Almquist, KC; Cole, SP; Deeley, RG; Loe, DW | 1 |
Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
Chang, CJ; McLaughlin, JL; Oberlies, NH | 1 |
Ahn, SH; Duffel, MW; Rosazza, JP | 1 |
Hargrove, P; Kim, RB; Lan, LB; Lecureur, V; Schuetz, EG; Schuetz, JD; Sun, D | 1 |
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
Borchardt, RT; Horie, K; Tang, F | 2 |
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
Gibbons, S; Kaatz, GW; Zloh, M | 1 |
Jolivette, LJ; Ward, KW | 1 |
Chattopadhyay, SK; Garg, A; Kaur, T; Khanuja, SP; Maulik, PR; Pal, A | 1 |
Burkett, BA; Chan, KF; Chan, TH; Chow, LM; Wong, IL; Zhao, Y | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Copper, JE; Gangjee, A; Smith, CD; Yu, J | 1 |
Attardo, G; Bubenick, M; Cai, SX; Crogan-Grundy, C; Denis, R; Drewe, J; Gourdeau, H; Jiang, S; Kasibhatla, S; Kemnitzer, W; Labreque, D; Lamothe, S; Tseng, B; Zhang, H | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Budde, C; Chen, X; Frank, AJ; Friedrich, T; Johnson, R; Leyhane, AJ; Liu, L; Manning, DD; Peace, D; Ralph, JM; Scott, IL; Stevens, JM; Surman, MD; Voss, ME; Wolf, M; Xie, D | 1 |
Hirasawa, Y; Hirata, T; Hosoya, T; Koyama, K; Kusumawati, I; Morita, H; Rahman, A; Shiro, M; Zaima, K; Zaini, NC | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA | 1 |
Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
Gangjee, A; Keller, SN; Namjoshi, OA; Smith, CD | 1 |
Chalmers, DK; Chaplin, JH; Charman, SA; Flynn, BL; Gill, GS; Grobelny, DW; Hamel, E; Jung, MK; Kostewicz, E; Kremmidiotis, G; Lavranos, TC; Leske, AF; Morizzi, J; Paul, D; Shackleford, DM | 1 |
Boger, DL; Duncan, KK; Gotoh, H; Robertson, WM | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Cheng, YY; Huang, LJ; Kuo, SC; Lee, KH; Lin, HY; Liu, CY; Tsai, MT; Wu, TS; Yang, JS | 1 |
Avery, VM; Sykes, ML | 1 |
Chao, SH; Chen, CH; Kakadiya, R; Lee, TC; Lin, YW; Ou, TH; Su, TL; Suman, S; Tala, KS; Tala, SD; Tsai, TH; Wu, MH | 1 |
Alfonsi, R; Bai, R; Bolognesi, A; Brancale, A; Coluccia, A; Di Marcotullio, L; Dondio, G; Famiglini, V; Gulino, A; Hamel, E; La Regina, G; Lavia, P; Mazzoccoli, C; Mercurio, C; Miele, A; Nalli, M; Novellino, E; Passacantilli, S; Pelliccia, S; Rensen, WM; Ruggieri, V; Silvestri, R; Sisinni, L; Varasi, M; Vultaggio, S | 1 |
Burckhardt, G; Flörl, S; Hagos, Y; Kühne, A; Marada, VV | 1 |
1 review(s) available for vinblastine and vincristine
Article | Year |
---|---|
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
40 other study(ies) available for vinblastine and vincristine
Article | Year |
---|---|
New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chemical Phenomena; Chemistry; Leukemia P388; Mice; Mice, Inbred DBA; Organophosphonates; Structure-Activity Relationship; Vinblastine | 1991 |
ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Cell Fractionation; Cell Membrane; Glutathione; Kinetics; Leukotriene E4; Liver; Male; Models, Biological; Rats; Rats, Inbred Strains; Sialic Acids; SRS-A | 1990 |
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
In vitro metabolic transformations of vinblastine: oxidations catalyzed by human ceruloplasmin.
Topics: Biotransformation; Catalysis; Cell Line; Ceruloplasmin; Humans; Leukemia, T-Cell; Oxidation-Reduction; Structure-Activity Relationship; Tumor Cells, Cultured; Vinblastine | 1989 |
In vitro metabolic transformations of vinblastine: oxidations catalyzed by peroxidase.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemical Phenomena; Chemistry; Drug Screening Assays, Antitumor; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Male; Mice; Oxidation-Reduction; Oxygen Isotopes; Tumor Cells, Cultured; Vinblastine; Vinca Alkaloids | 1989 |
Vinblastin-23-oyl amino acid derivatives: chemistry, physicochemical data, toxicity, and antitumor activities against P388 and L1210 leukemias.
Topics: Animals; Antineoplastic Agents, Phytogenic; Female; Lethal Dose 50; Leukemia L1210; Leukemia P388; Mice; Mice, Inbred DBA; Structure-Activity Relationship; Vinblastine; Vincristine; Vindesine | 1985 |
Cytotoxic constituents from Hyptis verticillata.
Topics: Animals; Antineoplastic Agents, Phytogenic; Artemia; Candida albicans; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Mexico; Mice; Microbial Sensitivity Tests; Plants, Medicinal; Podophyllotoxin; Rats | 1993 |
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.
Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Binding, Competitive; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Membrane; Epitopes; Estradiol; Glucuronates; HeLa Cells; Humans; Kinetics; Leukotriene C4; Lung Neoplasms; Mice; Protein Conformation; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1996 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Structure-activity relationships of diverse Annonaceous acetogenins against multidrug resistant human mammary adenocarcinoma (MCF-7/Adr) cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Furans; Humans; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1997 |
Oxidations of vincristine catalyzed by peroxidase and ceruloplasmin.
Topics: Antineoplastic Agents, Phytogenic; Biotransformation; Ceruloplasmin; Chromatography, Thin Layer; Drug Screening Assays, Antitumor; Humans; Leukemia, T-Cell; Magnetic Resonance Spectroscopy; Mass Spectrometry; Oxidation-Reduction; Peroxidases; Spectrophotometry, Infrared; Vinblastine; Vincristine | 1997 |
Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Humans; Karyotyping; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Sequence Homology, Amino Acid | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection | 2002 |
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?
Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine | 2002 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Taxoid from the needles of the Himalayan yew Taxus wallichiana with cytotoxic and immunomodulatory activities.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Concanavalin A; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Immunologic Factors; Lymphocytes; Models, Molecular; Molecular Conformation; Taxoids; Taxus; Vinblastine; Vincristine | 2006 |
Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance: synthetic apigenin homodimers linked with defined-length poly(ethylene glycol) spacers increase drug retention and enhance chemosensitivity in resistant cancer cells.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Apigenin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dimerization; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mice; Paclitaxel; Polyethylene Glycols; Structure-Activity Relationship; Vinblastine | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Discovery of novel antitumor antimitotic agents that also reverse tumor resistance.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cattle; Cell Cycle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Humans; Magnetic Resonance Spectroscopy; Mitosis; Tubulin; Vinblastine | 2007 |
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.
Topics: Antineoplastic Agents; Apoptosis; Benzopyrans; Caspases; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Indoles; Pyrroles; Structure-Activity Relationship; Tubulin Modulators | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Synthesis and SAR of vinca alkaloid analogues.
Topics: Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Leukemia P388; Mice; Molecular Structure; Structure-Activity Relationship; Vinblastine; Vinca Alkaloids; Vincristine | 2009 |
Biscarpamontamines A and B, an aspidosperma-iboga bisindole alkaloid and an aspidosperma-aspidosperma bisindole alkaloid, from Tabernaemontana sphaerocarpa.
Topics: Antineoplastic Agents, Phytogenic; Aspidosperma; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Indole Alkaloids; Indonesia; Molecular Structure; Plant Stems; Plants, Medicinal; Tabernaemontana | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mitosis; Molecular Structure; Pyrimidines; Pyrroles; Stereoisomerism; Structure-Activity Relationship | 2011 |
Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
Topics: Anisoles; Aorta; Benzofurans; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Humans; Neovascularization, Physiologic; Structure-Activity Relationship; Tubulin Modulators | 2011 |
10'-Fluorovinblastine and 10'-Fluorovincristine: Synthesis of a Key Series of Modified Vinca Alkaloids.
Topics: | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Design, synthesis, and mechanism of action of 2-(3-hydroxy-5-methoxyphenyl)-6-pyrrolidinylquinolin-4-one as a potent anticancer lead.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrrolidines; Quinolones; Structure-Activity Relationship | 2013 |
Design and synthesis of potent antitumor water-soluble phenyl N-mustard-benzenealkylamide conjugates via a bioisostere approach.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Nude; Mustard Compounds; Rats; Spectrometry, Mass, Electrospray Ionization | 2014 |
New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Guanidines; Hedgehog Proteins; Humans; M Phase Cell Cycle Checkpoints; Mice; Molecular Docking Simulation; Neoplasms; Polymerization; Protein Binding; Pyrroles; Signal Transduction; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2014 |
Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Humans; Liver-Specific Organic Anion Transporter 1; Molecular Structure; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Peptides; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2015 |