Page last updated: 2024-08-21

vinblastine and fosbretabulin

vinblastine has been researched along with fosbretabulin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's15 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barr, KJ; Claiborne, A; Credo, RB; Fitzgerald, M; Frost, D; Gehrke, L; Gwaltney, SL; Hui, YH; Kim, KH; Kovar, P; Lee, J; Li, Q; Liu, G; Marsh, K; Ng, SC; Nukkala, MA; Rosenberg, S; Sham, HL; Tahir, SK; Warner, RB; Woods, KW; Zielinski, NA1
Kobayashi, J; Koyama, K; Morita, H; Sugimoto, Y1
Cai, X; Duan, JX; Hart, C; Lan, L; Matteucci, M; Meng, F1
Chen, J; Dalton, JT; Li, CM; Li, W; Lu, Y; Meibohm, B; Miller, DD; Vaddady, PK; Wang, Z1
C-Gaudreault, R; Côté, MF; Fortin, S; Kotra, LP; Lacroix, J; Moreau, E; Petitclerc, E; Wei, L1
Baraldi, PG; Basso, G; Bortolozzi, R; Brancale, A; Hamel, E; Ricci, A; Romagnoli, R; Viola, G1
Chalmers, DK; Chaplin, JH; Charman, SA; Flynn, BL; Gill, GS; Grobelny, DW; Hamel, E; Jung, MK; Kostewicz, E; Kremmidiotis, G; Lavranos, TC; Leske, AF; Morizzi, J; Paul, D; Shackleford, DM1
Côté, MF; Fortin, S; Gaudreault, RC; Kotra, LP; Lacroix, J; Moreau, E; Petitclerc, E; Wei, L1
Balzarini, J; Baraldi, PG; Basso, G; Bortolozzi, R; Brancale, A; Fu, XH; Hamel, E; Kimatrai Salvador, M; Li, J; Lopez Cara, C; Romagnoli, R; Viola, G; Zhang, SZ1
Bai, R; Bolognesi, A; Brancale, A; Coluccia, A; Dondio, G; Ferlini, C; Gatti, V; Granata, I; Hamel, E; Iannitto, ML; La Regina, G; Lavecchia, A; Lavia, P; Maresca, B; Mariani, M; Mercurio, C; Novellino, E; Piscitelli, F; Porta, A; Rensen, W; Santoni, A; Silvestri, R; Soriani, A; Varasi, M1
Aghazadeh Tabrizi, M; Baraldi, PG; Basso, G; Bortolozzi, R; Brancale, A; Fu, XH; Hamel, E; Li, J; Porcù, E; Preti, D; Romagnoli, R; Salvador, MK; Viola, G; Zhang, SZ1
Baraldi, PG; Bassetto, M; Basso, G; Bortolozzi, R; Brancale, A; Camacho, ME; Hamel, E; Preti, D; Romagnoli, R; Salvador, MK; Tabrizi, MA; Viola, G1
Bai, R; Brancale, A; Chen, F; Coluccia, A; Costa, B; Da Pozzo, E; Di Cesare, E; Dondio, G; Famiglini, V; Granata, I; Hamel, E; Iannitto, ML; La Regina, G; Lavia, P; Li, J; Maresca, B; Martini, C; Mercurio, C; Miranda Cona, M; Nalli, M; Ni, Y; Novellino, E; Pelliccia, S; Piscitelli, F; Porta, A; Reggio, A; Rensen, WM; Santoni, A; Silvestri, R; Soriani, A; Varasi, M; Vultaggio, S1
Aghazadeh Tabrizi, M; Baraldi, PG; Bassetto, M; Basso, G; Bortolozzi, R; Brancale, A; Castagliuolo, I; Hamel, E; Kimatrai Salvador, M; Preti, D; Romagnoli, R; Viola, G1
Banuls, LM; Betancourt, T; Evdokimov, NM; Frolova, LV; Hamel, E; Hayden, K; Karki, M; Kiss, R; Kornienko, A; Lu, SL; Magedov, IV; Otero, I; Rastogi, SK; Rogelj, S; Romero, AE; Shuster, CB; Smith, WR1
Baraldi, PG; Basso, G; Bertolasi, V; Brancale, A; Cancellieri, M; Castagliuolo, I; Consolaro, F; Hamel, E; Porcù, E; Prencipe, F; Romagnoli, R; Salvador, MK; Viola, G1
Alfonsi, R; Bai, R; Bolognesi, A; Brancale, A; Coluccia, A; Di Marcotullio, L; Dondio, G; Famiglini, V; Gulino, A; Hamel, E; La Regina, G; Lavia, P; Mazzoccoli, C; Mercurio, C; Miele, A; Nalli, M; Novellino, E; Passacantilli, S; Pelliccia, S; Rensen, WM; Ruggieri, V; Silvestri, R; Sisinni, L; Varasi, M; Vultaggio, S1
Alfonsi, R; Bai, R; Bigogno, C; Brancale, A; Caraglia, M; Coluccia, A; Da Pozzo, E; Di Marcotullio, L; Dondio, G; Famiglini, V; Gulino, A; Hamel, E; La Regina, G; Lavia, P; Marinelli, L; Martini, C; Mazzoccoli, C; Mercurio, C; Miele, A; Monti, L; Nalli, M; Novellino, E; Passacantilli, S; Pelliccia, S; Porto, S; Ricci, B; Ruggieri, V; Santoni, A; Silvestri, R; Soriani, A; Varasi, M; Verrico, A; Vultaggio, S1

Other Studies

18 other study(ies) available for vinblastine and fosbretabulin

ArticleYear
Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent.
    Bioorganic & medicinal chemistry letters, 2002, Feb-11, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Biological Availability; Drug Screening Assays, Antitumor; Humans; Indoles; Mice; Microtubules; Models, Molecular; Oxazoles; Polymers; Rats; Stereoisomerism; Tubulin; Tumor Cells, Cultured

2002
Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata.
    Bioorganic & medicinal chemistry letters, 2005, Feb-15, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; K562 Cells; Phenanthrenes; Plants, Medicinal; Stilbenes; Tubulin Modulators

2005
Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles.
    Journal of medicinal chemistry, 2007, Mar-08, Volume: 50, Issue:5

    Topics: Acetylene; Animals; Binding Sites; Binding, Competitive; Cattle; Cell Line, Tumor; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indazoles; Radioligand Assay; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2007
Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents.
    Journal of medicinal chemistry, 2010, Oct-28, Volume: 53, Issue:20

    Topics: Animals; Binding Sites; Cell Line, Tumor; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Imidazoles; Mice; Mice, Inbred C57BL; Models, Molecular; Neoplasm Transplantation; Protein Binding; Protein Multimerization; Solubility; Structure-Activity Relationship; Transplantation, Heterologous; Tubulin; Tubulin Modulators

2010
Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Angiogenesis Inhibitors; Animals; Arylsulfonates; Benzene Derivatives; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Colchicine; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazolidines; Models, Molecular; Molecular Mimicry; Neovascularization, Physiologic; Quantitative Structure-Activity Relationship; Stilbenes; Transplantation, Heterologous; Tubulin Modulators

2011
Convergent synthesis and biological evaluation of 2-amino-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as microtubule targeting agents.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Microtubules; Mitosis; Models, Molecular; Protein Binding; Structure-Activity Relationship; Thiazoles; Tubulin Modulators

2011
Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
    Journal of medicinal chemistry, 2011, Sep-08, Volume: 54, Issue:17

    Topics: Anisoles; Aorta; Benzofurans; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Humans; Neovascularization, Physiologic; Structure-Activity Relationship; Tubulin Modulators

2011
Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Antimitotic Agents; Benzenesulfonamides; Binding Sites; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Colchicine; Humans; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Sulfonamides; Xenograft Model Antitumor Assays

2011
One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazole: a unique, highly active antimicrotubule agent.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:12

    Topics: Animals; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Cell Proliferation; Female; G2 Phase; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Thiazoles; Tubulin; Tubulin Modulators

2011
Design and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.
    Journal of medicinal chemistry, 2011, Dec-22, Volume: 54, Issue:24

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Caspase 3; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Furans; Humans; In Vitro Techniques; Indoles; Injections, Intravenous; Male; Mice; Mice, Nude; Microsomes, Liver; Pyrroles; Solubility; Structure-Activity Relationship; Thiophenes; Tubulin Modulators

2011
Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Activation; Humans; Hydroxybenzoates; Mice; Mice, Nude; Mitochondria; Models, Molecular; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Structure-Activity Relationship; Thiazoles; Thiophenes; Transplantation, Heterologous; Tubulin Modulators

2012
Synthesis and biological evaluation of 2-substituted-4-(3',4',5'-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents.
    Bioorganic & medicinal chemistry, 2012, Dec-15, Volume: 20, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colchicine; HeLa Cells; Humans; Microtubules; Models, Molecular; Structure-Activity Relationship; Thiazoles; Tubulin

2012
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
    Journal of medicinal chemistry, 2013, Jan-10, Volume: 56, Issue:1

    Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 Enzyme Inhibitors; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Imidazoles; Indoles; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Microsomes, Liver; Mitosis; Permeability; Polymerization; Pyridines; Reactive Oxygen Species; Rhabdomyosarcoma; Solubility; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2013
Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents.
    Journal of medicinal chemistry, 2013, Mar-28, Volume: 56, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Colchicine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lymphocytes; Mice; Mitochondria; Models, Molecular; Protein Multimerization; Protein Structure, Quaternary; Pyridines; Thiophenes; Tubulin; Xenograft Model Antitumor Assays

2013
Exploring natural product chemistry and biology with multicomponent reactions. 5. Discovery of a novel tubulin-targeting scaffold derived from the rigidin family of marine alkaloids.
    Journal of medicinal chemistry, 2013, Sep-12, Volume: 56, Issue:17

    Topics: Alkaloids; Biological Products; Colchicine; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tubulin

2013
Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
    Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15

    Topics: Angiogenesis Inhibitors; Aniline Compounds; Animals; Antimitotic Agents; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Liver Neoplasms; Mice, Inbred BALB C; Models, Molecular; Neoplasm Transplantation; Neoplastic Stem Cells; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Triazines; Triazoles; Tubulin; Tubulin Modulators

2014
New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
    Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15

    Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Guanidines; Hedgehog Proteins; Humans; M Phase Cell Cycle Checkpoints; Mice; Molecular Docking Simulation; Neoplasms; Polymerization; Protein Binding; Pyrroles; Signal Transduction; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2014
New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Animals; Cell Division; Cell Line, Tumor; Cytotoxicity, Immunologic; Drug Resistance, Neoplasm; Hedgehog Proteins; Humans; Indoles; Killer Cells, Natural; Mice; Mitosis; Neoplasms; NIH 3T3 Cells; Tubulin

2015