vidarabine phosphate and vidarabine

vidarabine phosphate has been researched along with vidarabine in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199051 (72.86)18.7374
1990's10 (14.29)18.2507
2000's6 (8.57)29.6817
2010's2 (2.86)24.3611
2020's1 (1.43)2.80

Authors

AuthorsStudies
De Clercq, E; Gosselin, G; Imbach, JL; Puech, F; qalzarini, J1
Fitzgerald, JE; Kurtz, SM; Schardein, JL1
Boezi, JA1
Cohen, SS; North, TW1
Falcon, MG; Jones, BR1
Pavan-Langston, D1
Jacob, ST; Leonard, TB1
Jacob, ST; Rose, KM1
Ouzan, D1
Chubb, S; Huang, P; Plunkett, W1
Dagnino, L; Paterson, AR1
Grever, MR; Malspeis, L; Staubus, AE; Young, D1
Gerber, MA; Lampertico, P; Malter, JS1
Berk, L; de Man, RA; Schalm, SW; Stijnen, T1
Catovsky, D; Davis, CL; Lister, TA; Mehta, AB; Ranson, M; Rohatiner, AZ; Rule, S; Smith, OP; Whelan, JS1
Biron, KK; Burnette, TC; de Miranda, P; Krenitsky, TA1
Fridland, A; Verhoef, V1
Farquhar, D; Smith, R1
Lok, AS; Novick, DM; Thomas, HC1
Crane, LR; Milne, DA1
Plunkett, W; Shewach, DS3
Barton, N; Hall, LM; McCann, WP; Siler, W; Whitley, RJ1
Lever, AM; Pignatelli, M; Scully, LJ; Thomas, HC1
Benson, CA; Kessler, HA; Levin, S; Pottage, JC; Trenholme, GM1
Kern, ER; Overall, JC; Richards, JT1
Börsch, G; Schmidt, G; Wegener, M1
Lever, AM; Pignatelli, M; Scully, LJ; Thomas, HC; Yap, I2
Burke, CA1
Hoofnagle, JH2
Chevallier, M; Chevallier, P; Chossegros, P; Degos, F; Fontanges, T; Hantz, O; Ouzan, D; Trépo, C1
Lever, AM1
Kufe, D; Matsukage, A; Ohno, T; Ohno, Y; Spriggs, D1
Gandhi, V; Plunkett, W2
Müller, R1
Altmann, R; Balboni, PG; Barbanti-Brodano, G; Busi, C; De Vries, J; Fiume, L; Mattioli, A; Wieland, T1
Felsenfeld, AD; Gerone, PJ; Gibson, S; Soike, KF1
Helland, S; Ueland, PM1
Chan, VL; Juranka, P1
Fukuoka, F; Nishimura, S; Okabe, M; Saneyoshi, M1
Gephart, JF; Lerner, AM1
Arnold, W; Hess, G; Meyer zum Büschenfelde, KH1
Brox, L; Lank, B; LePage, GA; Ng, PK; Preiksaitis, JK; Tyrrell, DL1
Benjamin, RS; Freireich, EJ; Keating, MJ; Plunkett, W1
Allaudeen, HS; Kozarich, JW; Sartorelli, AC1
Glasgow, LA; Kern, ER; Overall, JC; Richards, JT1
Merigan, TC; Smith, CI1
Busi, C; Fiume, L; Mattioli, A; Spinosa, G; Wieland, T1
Chance, D; Nahmias, AJ; Peters, J; Schinazi, RF; Williams, CC1
Bricaire, F; Brun-Vezinet, F; Huchon, A; Vilde, JL1
Ch'ien, LT; Griffith, JF1
Ayisi, NK; Gupta, VS; Meldrum, JB; Stuart, AL1
Carreño, V; Montaño, L; Torres, M1
Clark, G; Hersh, M; Hutton, JJ; Kuhn, J; Phillips, J; Von Hoff, DD1
Suzuki, H1
Fraternale, A; Magnani, M; Rossi, L1
Bosanquet, AG1
Akutsu, M; Bai, L; Furukawa, Y; Ichikawa, A; Kano, Y; Kon, K; Suzuki, K; Tsunoda, S1
Plunkett, W; Sampath, D1
Kamel, AM; Munson, B1
Bretonnet, AS; Cros, E; Dumontet, C; Gagnieu, MC; Galmarini, CM; Jordheim, LP; Krimm, I; Lancelin, JM1
Kamel, A; Munson, B1
Greenblatt, DJ; Karyagina, EV; Lister-James, J; Lundberg, AS; Yin, W1
Brunstein, CG; Cao, Q; Green, KG; Jacobson, PA; Long-Boyle, JR; McGlave, PB; Miller, JS; Rogosheske, J; Wagner, JE; Weisdorf, DJ1
Cen, S; Dong, D; Guo, F; Guo, S; Li, Q; Li, X; Liu, Q; Liu, Z; Ma, L; Wei, T; Yi, D; Zhang, Y; Zhao, J1

Reviews

11 review(s) available for vidarabine phosphate and vidarabine

ArticleYear
The antiherpesvirus action of phosphonoacetate.
    Pharmacology & therapeutics, 1979, Volume: 4, Issue:1

    Topics: Animals; Antiviral Agents; Cell Survival; DNA Replication; DNA, Viral; Drug Resistance, Microbial; Enzyme Induction; Herpesviridae; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Idoxuridine; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphorus Compounds; Phosphonoacetic Acid; Species Specificity; Vidarabine; Vidarabine Phosphate; Virus Replication

1979
Aranucleosides and aranucleotides in viral chemotherapy.
    Pharmacology & therapeutics, 1979, Volume: 4, Issue:1

    Topics: Animals; Arabinonucleosides; Arabinonucleotides; Cytarabine; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Hypoxanthines; Thymine; Vidarabine; Vidarabine Phosphate; Virus Diseases; Virus Replication

1979
Treatment of chronic viral hepatitis.
    Digestive diseases (Basel, Switzerland), 1991, Volume: 9, Issue:1

    Topics: Acyclovir; Hepatitis B; Hepatitis C; Hepatitis D; Hepatitis, Chronic; Humans; Interferons; Prednisolone; Vidarabine; Vidarabine Phosphate; Zidovudine

1991
Approaches to the treatment of hepatitis B virus and delta-related liver disease.
    Seminars in liver disease, 1986, Volume: 6, Issue:1

    Topics: Adult; Animals; Carrier State; Hepatitis B; Hepatitis B Antibodies; Hepatitis D; Hepatitis, Chronic; Humans; Infant, Newborn; Interferon Type I; Interferon-gamma; Interferons; Male; Pan troglodytes; Prednisone; Vidarabine; Vidarabine Phosphate

1986
A review of the efficacy of adenine arabinoside and lymphoblastoid interferon in the Royal Free Hospital studies of hepatitis B virus carrier treatment: identification of factors influencing response rates.
    Infection, 1987, Volume: 15 Suppl 1

    Topics: Arabinonucleotides; Carrier State; Hepatitis B; Homosexuality; Humans; Interferon Type I; Vidarabine; Vidarabine Phosphate

1987
Treatment of the chronic hepatitis B virus carrier state.
    The Journal of infection, 1988, Volume: 16, Issue:3

    Topics: Arabinonucleotides; Carrier State; Chronic Disease; Hepatitis B; Humans; Immune Tolerance; Interferons; Vidarabine; Vidarabine Phosphate

1988
Therapeutic approaches to chronic hepatitis B.
    Progress in liver diseases, 1982, Volume: 7

    Topics: Acyclovir; Adrenal Cortex Hormones; Antiviral Agents; Azathioprine; Chronic Disease; Guanine; Hepatitis B; Humans; Immunoglobulins; Interferons; Levamisole; Ribavirin; Transfer Factor; Vidarabine; Vidarabine Phosphate

1982
Herpes simplex virus encephalitis. Diagnostic and treatment considerations.
    The Medical clinics of North America, 1983, Volume: 67, Issue:5

    Topics: Acyclovir; Antibodies, Viral; Biopsy; Combined Modality Therapy; Electroencephalography; Encephalitis; Herpes Simplex; Humans; Pseudotumor Cerebri; Seizures; Simplexvirus; Tomography, Emission-Computed; Tomography, X-Ray Computed; Vidarabine; Vidarabine Phosphate

1983
[Treatment of chronic hepatitis B].
    Revista clinica espanola, 1983, Oct-15, Volume: 171, Issue:1

    Topics: Acyclovir; BCG Vaccine; Chronic Disease; Drug Therapy, Combination; Hepatitis B; Hepatitis B Antibodies; Humans; Interferons; Levamisole; Transfer Factor; Vidarabine; Vidarabine Phosphate

1983
[Antiviral therapy].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1984, Volume: 73, Issue:6

    Topics: Antiviral Agents; Hepatitis B; Humans; Interferons; Vidarabine; Vidarabine Phosphate

1984
Cellular and clinical pharmacology of fludarabine.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:2

    Topics: Antineoplastic Agents; Biological Availability; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Evaluation, Preclinical; Humans; Leukemia; Lymphoma; Phosphorylation; Vidarabine; Vidarabine Phosphate

2002

Trials

7 trial(s) available for vidarabine phosphate and vidarabine

ArticleYear
Current trends in therapy of ocular herpes simplex: experimental and clinical studies.
    Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie, 1979, Volume: 38

    Topics: Animals; Arabinonucleotides; Clinical Trials as Topic; Cornea; Guanine; Humans; Idoxuridine; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Trifluridine; Vidarabine; Vidarabine Phosphate

1979
Fludarabine phosphate for the treatment of low grade lymphoid malignancy.
    British journal of cancer, 1991, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Vidarabine; Vidarabine Phosphate

1991
A statistical view of clinical trials in chronic hepatitis B.
    Journal of hepatology, 1986, Volume: 3 Suppl 2

    Topics: Clinical Trials as Topic; Hepatitis B; Hepatitis, Chronic; Humans; Prognosis; Research Design; Statistics as Topic; Vidarabine; Vidarabine Phosphate

1986
Identification of factors influencing response rate to antiviral therapy of chronic hepatitis B virus infection. A review of the efficacy of adenine arabinoside and lymphoblastoid interferon in the Royal Free Hospital studies.
    Journal of hepatology, 1986, Volume: 3 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Arabinonucleotides; Carrier State; Clinical Trials as Topic; Hepatitis B; Hepatitis, Chronic; Homosexuality; Humans; Interferon Type I; Vidarabine; Vidarabine Phosphate

1986
Therapy of chronic type B hepatitis with adenine arabinoside and adenine arabinoside monophosphate.
    Journal of hepatology, 1986, Volume: 3 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Arabinonucleotides; Clinical Trials as Topic; Follow-Up Studies; Hepatitis B; Hepatitis, Chronic; Homosexuality; Humans; Male; Time Factors; Vidarabine; Vidarabine Phosphate

1986
Therapeutic activity of vidarabine in symptomatic chronic active hepatitis related to HBV.
    Journal of hepatology, 1986, Volume: 3 Suppl 2

    Topics: Clinical Trials as Topic; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis, Chronic; Humans; Interferons; Random Allocation; Vidarabine; Vidarabine Phosphate; Virus Replication

1986
High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation.
    Bone marrow transplantation, 2011, Volume: 46, Issue:1

    Topics: Adult; Aged; Drug Monitoring; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Metabolic Clearance Rate; Middle Aged; Neutrophil Infiltration; Prodrugs; Renal Insufficiency; Risk Factors; Survival Analysis; Transplantation Conditioning; Vidarabine; Vidarabine Phosphate; Young Adult

2011

Other Studies

52 other study(ies) available for vidarabine phosphate and vidarabine

ArticleYear
Synthesis and biological evaluation of isomeric dinucleoside monophosphates and monomethylphosphonates of 9-beta-D-arabinofuranosyladenine and related analogues.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Antiviral Agents; Arabinonucleotides; Cell Line; Chlorocebus aethiops; Humans; Isomerism; Mice; Prodrugs; Structure-Activity Relationship; Vidarabine Phosphate

1988
Comparative animal toxicology of vidarabine and its 5'-monophosphate.
    Annals of the New York Academy of Sciences, 1977, Mar-04, Volume: 284

    Topics: Animals; Arabinonucleotides; Carcinogens; Dogs; Drug Tolerance; Female; Irritants; Lethal Dose 50; Mice; Mutagens; Pregnancy; Rabbits; Rats; Teratogens; Time Factors; Vidarabine; Vidarabine Phosphate

1977
Acycloguanosine: antiviral activity in the rabbit cornea.
    The British journal of ophthalmology, 1979, Volume: 63, Issue:6

    Topics: Animals; Antiviral Agents; Dose-Response Relationship, Drug; Guanine; Idoxuridine; Keratitis, Dendritic; Rabbits; Trifluridine; Vidarabine; Vidarabine Phosphate

1979
Differential effects of cordycepin triphosphate and 9 beta-D-arabinofuranosyladenine triphosphate on tRNA and 5 S RNA synthesis in isolated nuclei.
    Biochimica et biophysica acta, 1979, Jun-20, Volume: 563, Issue:1

    Topics: Animals; Arabinonucleotides; Cell Nucleus; Deoxyadenine Nucleotides; In Vitro Techniques; Liver; Rats; RNA; RNA, Transfer; Vidarabine; Vidarabine Phosphate

1979
Selective inhibition of RNA polyadenylation by Ara-ATP in vitro: a possible mechanism for antiviral action of Ara-A.
    Biochemical and biophysical research communications, 1978, Apr-28, Volume: 81, Issue:4

    Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Cell Nucleus; Chromatin; Kinetics; Liver; Male; Nucleotidyltransferases; Polynucleotide Adenylyltransferase; Rats; RNA; Solubility; Vidarabine; Vidarabine Phosphate

1978
[Treatment of chronic hepatitis caused by hepatitis B virus].
    La Revue du praticien, 1990, May-11, Volume: 40, Issue:14

    Topics: Hepatitis B; Humans; Interferons; Vidarabine; Vidarabine Phosphate

1990
Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: Aphidicolin; Arabinonucleotides; Cell Line; Cell Survival; Clone Cells; Diterpenes; DNA Replication; DNA-Directed DNA Polymerase; Guanosine Monophosphate; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Vidarabine; Vidarabine Phosphate

1990
Sodium-dependent and equilibrative nucleoside transport systems in L1210 mouse leukemia cells: effect of inhibitors of equilibrative systems on the content and retention of nucleosides.
    Cancer research, 1990, Oct-15, Volume: 50, Issue:20

    Topics: Animals; Biological Transport; Dilazep; Dipyridamole; Formycins; Leukemia L1210; Mice; Nucleosides; Sodium; Thioinosine; Vidarabine; Vidarabine Phosphate

1990
Pharmacokinetics of 2-F-ara-A (9-beta-D-arabinofuranosyl-2-fluoroadenine) in cancer patients during the phase I clinical investigation of fludarabine phosphate.
    Seminars in oncology, 1990, Volume: 17, Issue:5 Suppl 8

    Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Drug Evaluation; Humans; Injections, Intravenous; Multivariate Analysis; Neoplasms; Vidarabine; Vidarabine Phosphate

1990
Development and application of an in vitro model for screening anti-hepatitis B virus therapeutics.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:3

    Topics: Antiviral Agents; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B; Hepatitis B virus; Humans; In Vitro Techniques; Interferon Type I; Stavudine; Vidarabine; Vidarabine Phosphate; Virus Replication; Zalcitabine; Zidovudine

1991
Selective anabolism of 6-methoxypurine arabinoside in varicella-zoster virus-infected cells.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10

    Topics: Arabinonucleosides; Cells, Cultured; Chromatography, High Pressure Liquid; Fibroblasts; Half-Life; Herpesvirus 3, Human; Humans; Vidarabine; Vidarabine Phosphate

1991
Metabolic basis of arabinonucleoside selectivity for human leukemic T- and B-lymphoblasts.
    Cancer research, 1985, Volume: 45, Issue:8

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; B-Lymphocytes; Cell Line; Cell Survival; Cytarabine; Deoxyguanosine; Humans; Leukemia; Phosphorylation; T-Lymphocytes; Vidarabine; Vidarabine Phosphate

1985
Synthesis and biological evaluation of 9-[5'-(2-oxo-1,3,2-oxazaphosphorinan-2-yl)-beta-D-arabinosyl]ade nine and 9-[5'-(2-oxo-1,3,2-dioxaphosphorinan-2-yl)-beta-D-arabinosyl]ade nine: potential neutral precursors of 9-[beta-D-arabinofuranosyl]adenine 5'-m
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: 5'-Nucleotidase; Adenosine Deaminase; Alkaline Phosphatase; AMP Deaminase; Animals; Arabinonucleotides; Biotransformation; Chemical Phenomena; Chemistry; Drug Stability; Female; Leukemia P388; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Nucleotidases; Organophosphorus Compounds; Phosphoric Diester Hydrolases; Vidarabine; Vidarabine Phosphate

1985
Diminished responsiveness of homosexual men to antiviral therapy for HBsAg-positive chronic liver disease.
    Journal of hepatology, 1985, Volume: 1, Issue:1

    Topics: Adult; Aspartate Aminotransferases; Carrier State; Chronic Disease; Hepatitis B; Hepatitis B Surface Antigens; Homosexuality; Humans; Immunity, Cellular; Interferon Type I; Liver Diseases; Male; Vidarabine; Vidarabine Phosphate

1985
Comparative activities of combinations of acyclovir, vidarabine or its 5'-monophosphate, and cloned human interferons against herpes simplex virus type 2 in human and mouse fibroblast cultures.
    Antiviral research, 1985, Volume: 5, Issue:6

    Topics: Acyclovir; Animals; Arabinonucleotides; Cell Line; Cytopathogenic Effect, Viral; Drug Synergism; Fibroblasts; Herpes Genitalis; Humans; Interferon Type I; Mice; Recombinant Proteins; Simplexvirus; Vidarabine; Vidarabine Phosphate

1985
Cellular retention of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and the pattern of recovery of DNA synthesis in Chinese hamster ovary cells.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Arabinonucleotides; Autoradiography; Cells, Cultured; Cricetinae; Cricetulus; DNA; Female; Ovary; Thymidine; Tritium; Vidarabine; Vidarabine Phosphate

1986
High-pressure liquid chromatographic methods for determining arabinosyladenine-5'-monophosphate, arabinosyladenine, and arabinosylhypoxanthine in plasma and urine.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2

    Topics: Arabinonucleosides; Arabinonucleotides; Chromatography, High Pressure Liquid; Creatinine; Herpes Zoster; Humans; Kidney; Metabolic Clearance Rate; Vidarabine; Vidarabine Phosphate

1985
Effects of suramin on in vitro HBsAg production by PLC/PRF/5 cells and hepatitis B virus DNA polymerase activity.
    AIDS research, 1986, Volume: 2, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Suramin; Vidarabine; Vidarabine Phosphate

1986
Acyclovir treatment of disseminated herpes simplex virus type 2 infection in weanling mice: alteration of mortality and pathogenesis.
    Antiviral research, 1986, Volume: 6, Issue:4

    Topics: Acyclovir; Administration, Oral; Animals; Brain; Female; Herpes Simplex; Humans; Infant, Newborn; Injections, Intravenous; Kidney; Lung; Mice; Olfactory Bulb; Pons; Simplexvirus; Spleen; Vidarabine; Vidarabine Phosphate

1986
[Drug therapy of chronic active hepatitis].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Mar-18, Volume: 81, Issue:6

    Topics: Autoimmune Diseases; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Vidarabine; Vidarabine Phosphate

1986
Antiviral treatment of chronic type B hepatitis.
    Annals of internal medicine, 1987, Volume: 107, Issue:3

    Topics: Antiviral Agents; Chronic Disease; Combined Modality Therapy; Hepatitis B; Hepatitis B virus; Humans; Interferon Type I; Vidarabine; Vidarabine Phosphate; Virus Replication

1987
Sequence-specific inhibition of DNA strand elongation by incorporation of 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1989, Apr-15, Volume: 49, Issue:8

    Topics: Base Sequence; Deoxyadenine Nucleotides; DNA; DNA Polymerase I; Vidarabine; Vidarabine Phosphate

1989
Interaction of arabinosyl nucleotides in K562 human leukemia cells.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; Arabinonucleotides; Cytarabine; Deoxyribonucleotides; Drug Interactions; Guanosine Triphosphate; Humans; Leukemia; Phosphorylation; Phosphotransferases; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate

1989
Fludarabine shows promise for some leukemia patients.
    Oncology (Williston Park, N.Y.), 1989, Volume: 3, Issue:3

    Topics: Antimetabolites, Antineoplastic; Arabinonucleotides; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Remission Induction; Vidarabine; Vidarabine Phosphate

1989
[Antiviral treatment of chronic hepatitis].
    Der Internist, 1984, Volume: 25, Issue:12

    Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis B; Hepatitis C; Hepatitis, Chronic; Hepatitis, Viral, Human; Humans; Interferons; Vidarabine; Vidarabine Phosphate

1984
Selective inhibition of Ectromelia virus DNA synthesis in hepatocytes by adenine-9-beta-D-arabinofuranoside (ara-A) and adenine-9-beta-D-arabinofuranoside 5'-monophosphate (ara-AMP) conjugated to asialofetuin.
    FEBS letters, 1980, Jul-28, Volume: 116, Issue:2

    Topics: alpha-Fetoproteins; Animals; Arabinonucleotides; Asialoglycoproteins; DNA Replication; DNA, Viral; Ectromelia virus; Fetuins; Intestine, Small; Liver; Male; Mice; Vidarabine; Vidarabine Phosphate

1980
Ineffectiveness of adenine arabinoside and adenine arabinoside 5'-monophosphate in simian varicella infection.
    Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:1

    Topics: Animals; Arabinonucleotides; Chickenpox; Chlorocebus aethiops; Disease Models, Animal; Erythrocebus patas; Female; Haplorhini; Herpesvirus 3, Human; Injections, Intramuscular; Injections, Intravenous; Male; Time Factors; Transaminases; Vidarabine; Vidarabine Phosphate

1980
Interaction of 9-beta-D-arabinofuranosyladenine, 9-beta-D-arabinofuranosyladenine 5'-monophosphate, and 9-beta-D-arabinofuranosyladenine 5'-triphosphate with S-adenosylhomocysteinase.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Adenosylhomocysteinase; Animals; Arabinonucleotides; Biotransformation; Hydrolases; Inactivation, Metabolic; Kinetics; Liver; Mice; Protein Binding; Vidarabine; Vidarabine Phosphate

1981
Relative cytotoxicity of 9-beta-D-arabinofuranosyladenine and 9-beta-D-arabinofuranosyladenine 5'-monophosphate.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Adenosine Kinase; Animals; Arabinonucleotides; Cell Line; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Kidney; Nucleotidases; Vidarabine; Vidarabine Phosphate

1980
Synthetic nucleosides and nucleotides. XIV. Facile synthesis and antitumor activities of 6-mercaptopurine 2'-deoxyriboside and related compounds.
    Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Deoxyribonucleosides; Female; Mercaptopurine; Mice; Mice, Inbred ICR; Purine Nucleosides; Sarcoma 180; Sarcoma, Experimental; Thioinosine; Thionucleosides; Vidarabine; Vidarabine Phosphate

1980
Comparison of the effects of arabinosyladenine, arabinosylhypoxanthine, and arabinosyladenine 5'-monophosphate against herpes simplex virus, varicella-zoster virus, and cytomegalovirus with their effects on cellular deoxyribonucleic acid synthesis.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:1

    Topics: Antiviral Agents; Arabinonucleosides; Arabinonucleotides; Cytomegalovirus; DNA, Viral; Herpesvirus 3, Human; Hypoxanthines; Microbial Sensitivity Tests; Simplexvirus; Vidarabine; Vidarabine Phosphate

1981
Inhibition of hepatitis B virus deoxyribonucleic acid polymerase by the 5'-triphosphates of 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:1

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Hepatitis B virus; Nucleic Acid Synthesis Inhibitors; Time Factors; Vidarabine; Vidarabine Phosphate

1981
Effect of liver disease on pharmacokinetics and toxicity of 9-beta-D-arabinofuranosyladenine-5-phosphate.
    The Journal of infectious diseases, 1981, Volume: 144, Issue:4

    Topics: Adult; Aged; Arabinonucleosides; Arabinonucleotides; Child; Female; Hepatitis B; Herpesviridae Infections; Humans; Hypoxanthines; Kinetics; Male; Middle Aged; Vidarabine; Vidarabine Phosphate

1981
Modulation of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and deoxyadenosine triphosphate in leukemic cells by 2'-deoxycoformycin during therapy with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Adult; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; DNA; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine; Vidarabine Phosphate

1982
Comparative effects of the 5'-triphosphates of 9-beta-(2'-azido-2'-deoxy-D-arabinofuranosyl)adenine and 9-beta-D-arabinofuranosyladenine on DNA polymerases from L1210 leukemia cells.
    Nucleic acids research, 1982, Feb-25, Volume: 10, Issue:4

    Topics: Animals; Arabinonucleotides; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; Kinetics; Leukemia L1210; Mice; Vidarabine; Vidarabine Phosphate

1982
Anti-herpesvirus activity of adenine arabinoside analogues in tissue culture and a genital infection of mice and guinea pigs.
    Antiviral research, 1982, Volume: 2, Issue:1-2

    Topics: Administration, Topical; Animals; Culture Techniques; Drug Evaluation, Preclinical; Female; Fibroblasts; Guinea Pigs; Herpes Genitalis; Male; Mice; Simplexvirus; Vidarabine; Vidarabine Phosphate

1982
Correlation of cytotoxicity with total intracellular exposure to 9-beta-D-arabinofuranosyladenine 5'-triphosphate.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Animals; Arabinonucleotides; Cell Line; Cell Survival; Coformycin; Cricetinae; Female; Kinetics; Ovary; Pentostatin; Vidarabine; Vidarabine Phosphate

1982
Effect of 2'-deoxycoformycin on the inhibition of deoxyribonucleic acid synthesis by 9-beta-D-arabinofuranosyladenine 5'-triphosphate.
    Biochemical pharmacology, 1982, Jun-01, Volume: 31, Issue:11

    Topics: Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Cells, Cultured; Coformycin; Cricetinae; Cricetulus; Deamination; DNA; Drug Interactions; Female; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; Thymidine; Time Factors; Vidarabine; Vidarabine Phosphate

1982
Conjugates of adenine 9-alpha-D-arabinofuranoside monophosphate (ara-AMP) with lactosaminated homologous albumin are not immunogenic in the mouse.
    Experientia, 1982, Sep-15, Volume: 38, Issue:9

    Topics: alpha-Fetoproteins; Animals; Antibodies; Arabinonucleotides; Asialoglycoproteins; Female; Fetuins; Hypersensitivity, Delayed; Lactose; Male; Mice; Rats; Rats, Inbred Strains; Serum Albumin; Species Specificity; Vidarabine; Vidarabine Phosphate

1982
Effect of combinations of acyclovir with vidarabine or its 5'-monophosphate on herpes simplex viruses in cell culture and in mice.
    Antimicrobial agents and chemotherapy, 1982, Volume: 22, Issue:3

    Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleotides; Drug Resistance, Microbial; Drug Synergism; Female; Herpes Simplex; Mice; Microbial Sensitivity Tests; Mutation; Simplexvirus; Vidarabine; Vidarabine Phosphate

1982
Comparative use of adenine arabinoside and adenine arabinoside monophosphate in varicella and disseminated zoster in immunosuppressed patients.
    Journal of medical virology, 1983, Volume: 12, Issue:2

    Topics: Adult; Aged; Arabinonucleotides; Child; Child, Preschool; Female; Herpes Zoster; Humans; Immune Tolerance; Male; Middle Aged; Solubility; Vidarabine; Vidarabine Phosphate

1983
Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate.
    Antiviral research, 1983, Volume: 3, Issue:3

    Topics: Animals; Antiviral Agents; Arabinonucleotides; Cell Survival; Deoxyuridine; Rabbits; Simplexvirus; Thymidine Monophosphate; Thymine Nucleotides; Vidarabine; Vidarabine Phosphate; Viral Plaque Assay; Virus Replication

1983
Phase I clinical investigation of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate (NSC 312887), a new purine antimetabolite.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Arabinonucleotides; Drug Evaluation; Female; Humans; Kinetics; Lung Neoplasms; Male; Neoplasms; Vidarabine; Vidarabine Phosphate

1984
Encapsulation, metabolism and release of 2-fluoro-ara-AMP from human erythrocytes.
    Biochimica et biophysica acta, 1996, Oct-24, Volume: 1291, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antimetabolites, Antineoplastic; Drug Carriers; Drug Delivery Systems; Erythrocytes; Humans; Kinetics; Phosphorylation; Vidarabine; Vidarabine Phosphate

1996
Re: V.I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Can
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Terminology as Topic; Vidarabine; Vidarabine Phosphate

1999
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
    Leukemia, 2000, Volume: 14, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine

2000
The role of c-Jun kinase in the apoptotic response to nucleoside analogue-induced DNA damage.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Antineoplastic Agents; Apoptosis; Arabinonucleotides; Caspases; DNA; DNA Damage; Enzyme Activation; Humans; Leukemia, Myeloid; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; S Phase; Tumor Cells, Cultured; U937 Cells; Vidarabine; Vidarabine Phosphate

2000
Collisionally-induced dissociation of purine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.
    European journal of mass spectrometry (Chichester, England), 2004, Volume: 10, Issue:2

    Topics: Acyclovir; Adenine; Antiviral Agents; Deuterium Exchange Measurement; Gases; Guanine; Hydrogen; Ions; Molecular Structure; Protons; Purines; Spectrometry, Mass, Electrospray Ionization; Vidarabine; Vidarabine Phosphate

2004
F-ara-AMP is a substrate of cytoplasmic 5'-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:3

    Topics: 5'-Nucleotidase; Chromatography, High Pressure Liquid; Cytoplasm; Humans; Kinetics; Magnetic Resonance Spectroscopy; Vidarabine; Vidarabine Phosphate

2006
Collision induced dissociation studies of alkali metal adducts of tetracyclines and antiviral agents by electrospray ionization, hydrogen/deuterium exchange and multiple stage mass spectrometry.
    European journal of mass spectrometry (Chichester, England), 2008, Volume: 14, Issue:5

    Topics: Acyclovir; Antiviral Agents; Deoxyuridine; Deuterium Exchange Measurement; Metals, Alkali; Purines; Spectrometry, Mass, Electrospray Ionization; Tetracyclines; Trifluridine; Vidarabine; Vidarabine Phosphate; Zidovudine

2008
Pharmacokinetics, bioavailability and effects on electrocardiographic parameters of oral fludarabine phosphate.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:1

    Topics: Administration, Oral; Adult; Biological Availability; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Half-Life; Heart Rate; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Chemical; Vidarabine; Vidarabine Phosphate

2010
5-Iodotubercidin inhibits SARS-CoV-2 RNA synthesis.
    Antiviral research, 2022, Volume: 198

    Topics: Antiviral Agents; Cell Line; COVID-19 Drug Treatment; Deoxyguanosine; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Thionucleosides; Tubercidin; Vidarabine; Vidarabine Phosphate

2022