Compounds > vidarabine phosphate

vidarabine phosphate and fludarabine

vidarabine phosphate has been researched along with fludarabine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's5 (33.33)18.2507
2000's4 (26.67)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Chubb, S; Huang, P; Plunkett, W1
Grever, MR; Malspeis, L; Staubus, AE; Young, D1
Catovsky, D; Davis, CL; Lister, TA; Mehta, AB; Ranson, M; Rohatiner, AZ; Rule, S; Smith, OP; Whelan, JS1
Gandhi, V; Plunkett, W2
Clark, G; Hersh, M; Hutton, JJ; Kuhn, J; Phillips, J; Von Hoff, DD1
Fraternale, A; Magnani, M; Rossi, L1
Bosanquet, AG1
Akutsu, M; Bai, L; Furukawa, Y; Ichikawa, A; Kano, Y; Kon, K; Suzuki, K; Tsunoda, S1
Plunkett, W; Sampath, D1
Bretonnet, AS; Cros, E; Dumontet, C; Gagnieu, MC; Galmarini, CM; Jordheim, LP; Krimm, I; Lancelin, JM1
Greenblatt, DJ; Karyagina, EV; Lister-James, J; Lundberg, AS; Yin, W1
Brunstein, CG; Cao, Q; Green, KG; Jacobson, PA; Long-Boyle, JR; McGlave, PB; Miller, JS; Rogosheske, J; Wagner, JE; Weisdorf, DJ1
Cen, S; Dong, D; Guo, F; Guo, S; Li, Q; Li, X; Liu, Q; Liu, Z; Ma, L; Wei, T; Yi, D; Zhang, Y; Zhao, J1

Reviews

1 review(s) available for vidarabine phosphate and fludarabine

ArticleYear
Cellular and clinical pharmacology of fludarabine.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:2

    Topics: Antineoplastic Agents; Biological Availability; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Evaluation, Preclinical; Humans; Leukemia; Lymphoma; Phosphorylation; Vidarabine; Vidarabine Phosphate

2002

Trials

2 trial(s) available for vidarabine phosphate and fludarabine

ArticleYear
Fludarabine phosphate for the treatment of low grade lymphoid malignancy.
    British journal of cancer, 1991, Volume: 64, Issue:1

    Topics: Antineoplastic Agents; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Vidarabine; Vidarabine Phosphate

1991
High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation.
    Bone marrow transplantation, 2011, Volume: 46, Issue:1

    Topics: Adult; Aged; Drug Monitoring; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Metabolic Clearance Rate; Middle Aged; Neutrophil Infiltration; Prodrugs; Renal Insufficiency; Risk Factors; Survival Analysis; Transplantation Conditioning; Vidarabine; Vidarabine Phosphate; Young Adult

2011

Other Studies

12 other study(ies) available for vidarabine phosphate and fludarabine

ArticleYear
Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity.
    The Journal of biological chemistry, 1990, Sep-25, Volume: 265, Issue:27

    Topics: Aphidicolin; Arabinonucleotides; Cell Line; Cell Survival; Clone Cells; Diterpenes; DNA Replication; DNA-Directed DNA Polymerase; Guanosine Monophosphate; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Vidarabine; Vidarabine Phosphate

1990
Pharmacokinetics of 2-F-ara-A (9-beta-D-arabinofuranosyl-2-fluoroadenine) in cancer patients during the phase I clinical investigation of fludarabine phosphate.
    Seminars in oncology, 1990, Volume: 17, Issue:5 Suppl 8

    Topics: Antimetabolites, Antineoplastic; Chromatography, High Pressure Liquid; Drug Evaluation; Humans; Injections, Intravenous; Multivariate Analysis; Neoplasms; Vidarabine; Vidarabine Phosphate

1990
Interaction of arabinosyl nucleotides in K562 human leukemia cells.
    Biochemical pharmacology, 1989, Oct-15, Volume: 38, Issue:20

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleosides; Arabinonucleotides; Cytarabine; Deoxyribonucleotides; Drug Interactions; Guanosine Triphosphate; Humans; Leukemia; Phosphorylation; Phosphotransferases; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate

1989
Fludarabine shows promise for some leukemia patients.
    Oncology (Williston Park, N.Y.), 1989, Volume: 3, Issue:3

    Topics: Antimetabolites, Antineoplastic; Arabinonucleotides; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Remission Induction; Vidarabine; Vidarabine Phosphate

1989
Phase I clinical investigation of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate (NSC 312887), a new purine antimetabolite.
    Cancer research, 1984, Volume: 44, Issue:9

    Topics: Adenocarcinoma; Arabinonucleotides; Drug Evaluation; Female; Humans; Kinetics; Lung Neoplasms; Male; Neoplasms; Vidarabine; Vidarabine Phosphate

1984
Encapsulation, metabolism and release of 2-fluoro-ara-AMP from human erythrocytes.
    Biochimica et biophysica acta, 1996, Oct-24, Volume: 1291, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antimetabolites, Antineoplastic; Drug Carriers; Drug Delivery Systems; Erythrocytes; Humans; Kinetics; Phosphorylation; Vidarabine; Vidarabine Phosphate

1996
Re: V.I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Can
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Terminology as Topic; Vidarabine; Vidarabine Phosphate

1999
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
    Leukemia, 2000, Volume: 14, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine

2000
The role of c-Jun kinase in the apoptotic response to nucleoside analogue-induced DNA damage.
    Cancer research, 2000, Nov-15, Volume: 60, Issue:22

    Topics: Antineoplastic Agents; Apoptosis; Arabinonucleotides; Caspases; DNA; DNA Damage; Enzyme Activation; Humans; Leukemia, Myeloid; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; S Phase; Tumor Cells, Cultured; U937 Cells; Vidarabine; Vidarabine Phosphate

2000
F-ara-AMP is a substrate of cytoplasmic 5'-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation.
    Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:3

    Topics: 5'-Nucleotidase; Chromatography, High Pressure Liquid; Cytoplasm; Humans; Kinetics; Magnetic Resonance Spectroscopy; Vidarabine; Vidarabine Phosphate

2006
Pharmacokinetics, bioavailability and effects on electrocardiographic parameters of oral fludarabine phosphate.
    Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:1

    Topics: Administration, Oral; Adult; Biological Availability; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Half-Life; Heart Rate; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Chemical; Vidarabine; Vidarabine Phosphate

2010
5-Iodotubercidin inhibits SARS-CoV-2 RNA synthesis.
    Antiviral research, 2022, Volume: 198

    Topics: Antiviral Agents; Cell Line; COVID-19 Drug Treatment; Deoxyguanosine; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Thionucleosides; Tubercidin; Vidarabine; Vidarabine Phosphate

2022