Page last updated: 2024-08-22

vidarabine and coformycin

vidarabine has been researched along with coformycin in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199036 (92.31)18.7374
1990's3 (7.69)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arendes, J; Maidhof, A; Müller, WE; Umezawa, H; Zahn, RK1
Alexander, L; Chubb, S; Loo, TL; Plunkett, W2
Bryant, PE; MacLeod, RA1
Ayer, SW; Isaac, BG; Letendre, LJ; Stonard, RJ1
Hirose, M; Inaba, S; Kuroki, Y; Shimoyama, M1
Butkiewicz, NJ; Lieberman, M; Lim, J; Lin, C; Miller, GH; Ostrander, M; Schwartz, J1
Matsumoto, SS; Mendelsohn, J; Yu, AL1
O'Brien, WJ1
Helland, S; Ueland, PM2
Heike, T; Katamura, K; Kubota, M; Mikawa, H; Shinomiya, K1
Kontinen, VP; Pispa, JP1
Iliakis, G; Ngo, FQ1
Hsiao, N; Lum, CT; Najarian, JS; Sutherland, DE1
Plunkett, W1
Tunac, JB; Underhill, M1
Drach, JC; Novack, J; Schwartz, PM; Shipman, C1
Coen, DM; Fleming, HE1
Benjamin, RS; Freireich, EJ; Keating, MJ; Plunkett, W1
Plunkett, W; Shewach, DS2
Coleman, MS; Siaw, MF1
O'Brien, WJ; Taylor, JL1
Allen, LB; Cook, PD; Fingal, CM; Harris, EF; McCright, FH; Vanderslice, LK1
Bastow, KF; Cheng, YC; Derse, DD1
Akagi, K; Sougawa, M; Tanaka, Y; Yoshii, G1
Benjamin, RS; Feun, LG; Freirich, EJ; Keating, M; Nowak, B; Plunkett, W1
Agarwal, RP; Kufe, DW; Major, PP1
Falletta, JM; Hershfield, MS; Kinney, TR; Koller, CA; Kredich, NM; Kurtzberg, J; Mitchell, BS1
Cass, CE; Phillips, JR; Selner, M1
Gorecki, P; Lum, CT; Matas, AJ; Najarian, JS; Payne, WD; Sutherland, DE1
Alexander, L; Chubb, S; Montgomery, JA; Plunkett, W1
Coleman, MS; Deibel, MR; Hutton, JJ1
Christian, R; Lee, SH; Sartorelli, AC; Thomas, LK; Unger, FM1
Balcerzak, SP; Coleman, MS; Gray, DP; Grever, MR; Siaw, MF1
Agarwal, RP; Blatt, J; Holcenberg, J; Lipton, JM; Miser, J; Poplack, DG; Reaman, GH; Sallan, S1
Hidaka, T; Katayama, K; Ohno, M; Shimazaki, M; Takeuchi, T; Umezawa, H; Watanabe, K; Yamashita, K; Yamashita, T1
Cawley, JC; Clarke, AR; Griffiths, SD; Pettitt, AR1

Trials

2 trial(s) available for vidarabine and coformycin

ArticleYear
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials as Topic; Coformycin; DNA; Drug Evaluation; Drug Synergism; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Male; Mice; Nucleoside Deaminases; Pentostatin; Thymidine; Vidarabine

1985
Modulation of arabinosyladenine metabolism by 2'-deoxycoformycin in the therapy of human acute leukemia.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenosine Deaminase; Antineoplastic Agents; Clinical Trials as Topic; Coformycin; Erythrocytes; Humans; Kinetics; Leukemia; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Vidarabine

1984

Other Studies

37 other study(ies) available for vidarabine and coformycin

ArticleYear
Influence of coformycin on the cytostatic activity of 9-beta-D-arabinofuranosyladenine and adenosine in mouse L5178y cells.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1978, Volume: 359, Issue:10

    Topics: Adenosine; Cell Division; Cell Line; Coformycin; Deoxyadenosines; Kinetics; Ribonucleosides; Vidarabine

1978
Comparison of the activity of 2'-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl)adenine in vivo.
    Biochemical pharmacology, 1979, Volume: 28, Issue:2

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Cells, Cultured; Coformycin; DNA, Neoplasm; Female; Leukemia, Experimental; Mice; Nucleoside Deaminases; Ribonucleosides; Time Factors; Vidarabine

1979
Biochemical basis of the increased activity of 9-beta-D-arabinofuranosyladenine in the presence of inhibitors of adenosine deaminase.
    Cancer research, 1979, Volume: 39, Issue:9

    Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Bone Marrow; Cell Line; Coformycin; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred Strains; Nucleoside Deaminases; Ribonucleosides; Time Factors; Vidarabine

1979
Effects of adenine arabinoside and coformycin on the kinetics of G2 chromatid aberrations in X-irradiated human lymphocytes.
    Mutagenesis, 1992, Volume: 7, Issue:4

    Topics: Chromatids; Chromosome Aberrations; Coformycin; DNA; G2 Phase; Humans; Kinetics; Lymphocytes; Sister Chromatid Exchange; Vidarabine

1992
Herbicidal nucleosides from microbial sources.
    The Journal of antibiotics, 1991, Volume: 44, Issue:7

    Topics: Actinomycetales; Chromatography, High Pressure Liquid; Coformycin; Deoxyguanosine; Fermentation; Herbicides; Inosine; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleosides; Purine Nucleosides; Toyocamycin; Vidarabine

1991
Potentiation of growth-inhibitory activity of 9-beta-D-arabinofuranosyladenine by 2'-deoxycoformycin in human cultured cell lines derived from leukemias and lymphomas.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:5

    Topics: Adenosine Deaminase; Antineoplastic Agents; Cell Division; Coformycin; Drug Stability; Drug Synergism; Humans; Leukemia; Lymphoma; Pentostatin; Ribonucleosides; Tumor Cells, Cultured; Vidarabine

1989
Activity of (+)-cyclaradine (Sch 31172) against herpes simplex virus in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Acyclovir; Animals; Cell Line; Coformycin; Female; Guinea Pigs; Herpes Simplex; Humans; Pentostatin; Simplexvirus; Vero Cells; Vidarabine

1987
Induction of complete remission in T-cell acute lymphoblastic leukemia with deoxycoformycin (dcf) and 9-beta-D-arabinofuranosyladenine (ara-A).
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adult; Antigens, Surface; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Coformycin; Drug Administration Schedule; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine

1986
Therapy with 9-beta-D-arabinofuranosyladenine (ARA-A) and 2'-deoxycoformycin increases the ARA-A content of ocular tissues.
    Current eye research, 1986, Volume: 5, Issue:8

    Topics: Animals; Arabinonucleosides; Chromatography; Coformycin; Eye; Keratitis, Dendritic; Pentostatin; Rabbits; Ribonucleosides; Vidarabine

1986
Determination of S-adenosylhomocysteine in tissues following pharmacological inhibition of S-adenosylhomocysteine catabolism.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Adenosylhomocysteinase; Animals; Coformycin; Freezing; Homocysteine; Hydrolases; Mice; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Tissue Distribution; Vidarabine

1986
Inhibitor of 2', 5'-oligoadenylate synthetase induced in human T lymphoblastoid cell line treated with deoxyadenosine, deoxycoformycin and interferon.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: 2',5'-Oligoadenylate Synthetase; Adenosine; Cell Line; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Enzyme Induction; Homocysteine; Humans; Interferon Type I; Pentostatin; Ribonucleosides; T-Lymphocytes; Vidarabine

1986
Enhancement of biotinidase activity in mouse serum by inhibitors of methylation.
    Molecular and cellular biochemistry, 1987, Volume: 76, Issue:1

    Topics: Adenine; Adenosine; Amidohydrolases; Animals; Biotinidase; Coformycin; Ethionine; Female; Liver; Methylation; Mice; Pentostatin; Vidarabine

1987
Effects of adenosine deaminase inhibitor 2'-deoxycoformycin on the repair and expression of potentially lethal damage sensitive to beta-araA.
    Radiation and environmental biophysics, 1985, Volume: 24, Issue:2

    Topics: Adenosine Deaminase Inhibitors; Animals; Cell Line; Cell Survival; Coformycin; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; In Vitro Techniques; Nucleoside Deaminases; Pentostatin; Ribonucleosides; Vidarabine

1985
Relevance of adenosine deaminase to organ transplantation.
    Annals of the New York Academy of Sciences, 1985, Volume: 451

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Coformycin; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nucleoside Deaminases; Pentostatin; Skin Transplantation; Splenectomy; T-Lymphocytes; Vidarabine

1985
2'-Chloropentostatin: discovery, fermentation and biological activity.
    The Journal of antibiotics, 1985, Volume: 38, Issue:10

    Topics: Actinomycetales; Adenosine Deaminase Inhibitors; Anti-Bacterial Agents; Biological Assay; Coformycin; Enterococcus faecalis; Fermentation; Nucleosides; Pentostatin; Vidarabine

1985
Metabolism of arabinosyladenine in herpes simplex virus-infected and uninfected cells. Correlation with inhibition of DNA synthesis and role in antiviral selectivity.
    Biochemical pharmacology, 1984, Aug-01, Volume: 33, Issue:15

    Topics: Arabinose; Coformycin; Deamination; DNA; Herpes Simplex; Humans; Nasopharyngeal Neoplasms; Pentosephosphates; Phosphorylation; Simplexvirus; Vidarabine; Virus Cultivation; Virus Replication

1984
Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:3

    Topics: Animals; Coformycin; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Genetic Markers; Mutation; Pentostatin; Ribonucleosides; Simplexvirus; Vidarabine

1984
Modulation of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and deoxyadenosine triphosphate in leukemic cells by 2'-deoxycoformycin during therapy with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Adult; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; DNA; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine; Vidarabine Phosphate

1982
Correlation of cytotoxicity with total intracellular exposure to 9-beta-D-arabinofuranosyladenine 5'-triphosphate.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Animals; Arabinonucleotides; Cell Line; Cell Survival; Coformycin; Cricetinae; Female; Kinetics; Ovary; Pentostatin; Vidarabine; Vidarabine Phosphate

1982
Effect of 2'-deoxycoformycin on the inhibition of deoxyribonucleic acid synthesis by 9-beta-D-arabinofuranosyladenine 5'-triphosphate.
    Biochemical pharmacology, 1982, Jun-01, Volume: 31, Issue:11

    Topics: Adenosine Deaminase Inhibitors; Animals; Arabinonucleotides; Cells, Cultured; Coformycin; Cricetinae; Cricetulus; Deamination; DNA; Drug Interactions; Female; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; Thymidine; Time Factors; Vidarabine; Vidarabine Phosphate

1982
In vitro metabolism of deoxycoformycin in human T lymphoblastoid cells. Phosphorylation of deoxycoformycin and incorporation into cellular DNA.
    The Journal of biological chemistry, 1984, Aug-10, Volume: 259, Issue:15

    Topics: Adenosine Deaminase Inhibitors; Adenosine Kinase; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine Kinase; DNA; Humans; Nucleoside Deaminases; Pentostatin; Phosphorylation; Ribonucleosides; RNA; T-Lymphocytes; Vidarabine

1984
Chemotherapy of herpetic keratitis induced by acyclovir-resistant strains of herpes simplex virus type 1.
    The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A

    Topics: Acyclovir; Animals; Antiviral Agents; Coformycin; Drug Resistance, Microbial; Drug Therapy, Combination; Guanine; Keratitis, Dendritic; Mutation; Pentostatin; Rabbits; Simplexvirus; Thymidine Kinase; Trifluridine; Vidarabine

1982
Evaluation of the anti-herpesvirus drug combinations: virazole plus arabinofuranosylhypoxanthine and virazole plus arabinofuranosyladenine.
    Antiviral research, 1982, Volume: 2, Issue:4

    Topics: Animals; Arabinonucleosides; Cell Line; Cell Survival; Coformycin; Cricetinae; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Humans; Pentostatin; Ribavirin; Ribonucleosides; Simplexvirus; Vidarabine

1982
Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:6

    Topics: Antiviral Agents; Aphidicolin; Arabinonucleosides; Coformycin; Diterpenes; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Pentostatin; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase; Vidarabine

1983
[Problems of antineoplastic effects by PLDR (potential lethal damage repair) inhibitor--pharmacokinetics].
    Gan no rinsho. Japan journal of cancer clinics, 1984, Volume: 30, Issue:14

    Topics: Adenocarcinoma; Aged; Animals; Chromatography, High Pressure Liquid; Coformycin; Combined Modality Therapy; Drug Synergism; Female; Humans; Kinetics; Lung Neoplasms; Mice; Mice, Inbred BALB C; Pentostatin; Rabbits; Rats; Rats, Inbred F344; Ribonucleosides; Vidarabine

1984
Clinical pharmacology of arabinofuranosyladenine in combination with deoxycoformycin.
    Cancer chemotherapy and pharmacology, 1983, Volume: 10, Issue:2

    Topics: Adenosine; Adult; Antineoplastic Agents; Coformycin; Deoxyadenosines; Drug Administration Schedule; Drug Therapy, Combination; Half-Life; Humans; Kinetics; Leukemia; Male; Pentostatin; Ribonucleosides; Vidarabine

1983
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Acute Disease; Adenosine; Adult; Coformycin; Deoxyadenosines; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Homocysteine; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Pentostatin; Ribonucleosides; S-Adenosylhomocysteine; Time Factors; Vidarabine

1983
Resistance to 9-beta-D-arabinofuranosyladenine in cultured leukemia L 1210 cells.
    Cancer research, 1983, Volume: 43, Issue:10

    Topics: Adenosine Kinase; Animals; Cell Division; Coformycin; DNA Replication; Drug Resistance; Leukemia L1210; Mice; Pentostatin; Tubercidin; Vidarabine

1983
Prolongation of mouse and rat pancreatic islet cell allografts by adenosine deaminase inhibitors and adenine arabinoside.
    The Journal of surgical research, 1980, Volume: 28, Issue:1

    Topics: Animals; Coformycin; Diabetes Mellitus, Experimental; Female; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pentostatin; Rats; Rats, Inbred Lew; Ribonucleosides; Transplantation, Homologous; Vidarabine

1980
Comparison of the toxicity and metabolism of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine in human lymphoblastoid cells.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Antineoplastic Agents; Cells, Cultured; Coformycin; DNA; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphoid; T-Lymphocytes; Vidarabine

1980
Effect of adenosine deaminase inhibitors on the apparent rate of phosphorylation of deoxyadenosine.
    Biochemical medicine, 1981, Volume: 25, Issue:3

    Topics: Adenine; Adenosine Deaminase Inhibitors; Cell Line; Coformycin; Deoxyadenosines; Enzyme Inhibitors; Humans; Leukemia, Lymphoid; Nucleoside Deaminases; Pentostatin; Phosphorylation; Vidarabine

1981
Comparative antineoplastic activity against P388 leukemia of 9-beta-D-arabinofuranosyladenine (araA) and 9-beta-(2'-azido-2'-deoxy-D-arabinofuranosyl) adenine (arazide).
    International journal of cancer, 1981, May-15, Volume: 27, Issue:5

    Topics: Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Cells, Cultured; Coformycin; DNA, Neoplasm; Drug Therapy, Combination; Leukemia P388; Leukemia, Experimental; Mice; Pentostatin; Vidarabine

1981
2'-deoxycoformycin (DCF) and 9-beta-D-arabinofuranosyladenine (Ara-A) in the treatment of refractory acute myelocytic leukemia.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Adenosine Deaminase; Adult; Coformycin; Deoxyribonucleotides; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Male; Nucleosides; Pentostatin; Ribonucleosides; Ribonucleotides; Vidarabine

1982
Reactivation of S-adenosylhomocysteine hydrolase activity in cells exposed to 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosylhomocysteinase; Animals; Cell Line; Cells, Cultured; Coformycin; Enzyme Activation; Fibroblasts; Homocysteine; Hydrolases; Inosine; Liver; Mice; Pentostatin; Plasmacytoma; Rats; Vidarabine

1982
Clinical pharmacology of 9-beta-D-arabinofuranosyladenine in combination with 2'-deoxycoformycin.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: Adolescent; Adult; Arabinonucleosides; Child, Preschool; Coformycin; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Hypoxanthines; Kinetics; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine

1982
Effects of a new adenosine deaminase inhibitor, isocoformycin, on toxicity, antitumor activity and tissue distribution of formycin A and 9-beta-D-arabinofuranosyladenine.
    The Journal of antibiotics, 1980, Volume: 33, Issue:3

    Topics: Adenosine Deaminase Inhibitors; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Coformycin; Drug Synergism; Female; Formycins; Mice; Nucleoside Deaminases; Ribonucleosides; Tissue Distribution; Vidarabine

1980
Purine analogues kill resting lymphocytes by p53-dependent and -independent mechanisms.
    British journal of haematology, 1999, Volume: 105, Issue:4

    Topics: Animals; Cell Death; Cladribine; Coformycin; Dexamethasone; Drug Resistance; Etoposide; Genes, p53; Lymphocytes; Mice; Mice, Knockout; Spleen; Vidarabine

1999