vesnarinone has been researched along with amrinone in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 10 (62.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erhardt, PW | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Blinks, JR; Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Hosokawa, T; Kojima, M; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Hashimoto, K; Mori, T; Yabuuchi, Y; Yamashita, S | 1 |
| Han, W; Qin, Y; Yang, Z; Zhang, Z; Zhou, S | 1 |
| Matoba, Y; Matsui, S; Matsumori, A; Sasayama, S; Uchida, A | 1 |
| Miyoshi, Y; Nakaya, Y; Nomura, M; Saito, K; Shono, M; Wakatsuki, T | 1 |
| Matsumori, A; Sasayama, S; Sato, Y | 1 |
| Matsumori, A; Sasayama, S | 1 |
| Furukawa, Y; Iwasaki, A; Matsumori, A; Nakamura, T; Okada, I; Ono, K; Sasayama, S; Shioi, T | 1 |
| Matsumori, A; Nose, Y; Ono, K; Sasayama, S; Sato, Y; Shioi, T | 1 |
| Cao-Danh, H; Cowan, DB; del Nido, PJ; Friehs, I; Glynn, P; Ibrahim, AE; McGowan, FX; Poutias, D; Takeuchi, K | 1 |
| Sawada, M; Suzumura, A; Takayanagi, T; Tamaru, T; Yoshikawa, M | 1 |
| Matsumori, A; Nunokawa, Y; Sasayama, S | 1 |
1 review(s) available for vesnarinone and amrinone
| Article | Year |
|---|---|
In search of the digitalis replacement.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1987 |
15 other study(ies) available for vesnarinone and amrinone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Imidazoles; Male; Milrinone; Myocardial Contraction; Myocardium; Nifedipine; Nucleotides, Cyclic; Pyrazines; Pyridones; Quinolines; Time Factors | 1986 |
In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals.
Topics: Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Cats; Dobutamine; Dogs; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phentolamine; Pindolol; Pyrazines; Quinolines; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Theophylline | 1984 |
Positive inotropic effect of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212) in the dog with experimentally-induced right-sided heart failure.
Topics: Administration, Oral; Aminopyridines; Amrinone; Animals; Blood Pressure; Cardiotonic Agents; Dobutamine; Dogs; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Injections, Intravenous; Male; Myocardial Contraction; Pyrazines; Quinolines | 1984 |
[Inotropic effect of novel domestic cardiotonic agent, vesnarinone--test in vitro].
Topics: Amrinone; Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Milrinone; Myocardial Contraction; Pyrazines; Pyridones; Quinolines; Rabbits; Stimulation, Chemical | 1994 |
Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production.
Topics: Amrinone; Animals; Cardiomyopathies; Cardiovirus Infections; Encephalomyocarditis virus; Female; Immunosuppressive Agents; Killer Cells, Natural; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Myocardium; Pregnancy; Pyrazines; Quinolines; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Effects of vesnarinone (OPC-8212) on Ca(2+)-activated K channels and cytosolic Ca2+ in cultured smooth muscle cells from porcine coronary artery.
Topics: Amrinone; Animals; Arteries; Calcium; Carbachol; Cardiotonic Agents; Cells, Cultured; Coronary Vessels; Cyclic AMP; Cytosol; Muscle, Smooth, Vascular; Potassium Channels; Pyrazines; Quinolines; Swine | 1994 |
Inotropic agent vesnarinone inhibits cytokine production and E-selectin expression in human umbilical vein endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Cardiotonic Agents; Cell Adhesion; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Depression, Chemical; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; Heart Failure; Hematopoietic Cell Growth Factors; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; Neutropenia; Pyrazines; Quinolines; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1995 |
Role of cytokines in the syndrome of heart failure.
Topics: Adrenergic beta-Agonists; Amrinone; Animals; Cardiotonic Agents; Cytokines; Heart Failure; Humans; Killer Cells, Natural; Myocarditis; Phosphodiesterase Inhibitors; Pyrazines; Quinolines; Tumor Necrosis Factor-alpha | 1996 |
Inotropic agents differentially inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Animals; Cardiotonic Agents; Cell Line; Culture Media; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase; Nitrites; Phosphodiesterase Inhibitors; Pyrazines; Pyridazines; Quinolines | 1996 |
Differential modulation of cytokine production by drugs: implications for therapy in heart failure.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Cells, Cultured; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Heart Failure; Humans; Interleukin-1; Interleukin-6; Kinetics; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperidines; Pyrazines; Pyridazines; Quinazolines; Quinolines; Tumor Necrosis Factor-alpha | 1996 |
Vesnarinone and amrinone reduce the systemic inflammatory response syndrome.
Topics: Adjuvants, Immunologic; Amrinone; Animals; Drug Evaluation, Preclinical; Endotoxemia; Endotoxins; Heart; Inflammation Mediators; Interleukin-1; Lung; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Pyrazines; Quinolines; Rabbits; Salmonella typhimurium; Systemic Inflammatory Response Syndrome; Time Factors; Tumor Necrosis Factor-alpha | 1999 |
Severe heart failure: balancing length and quality of life.
Topics: Amrinone; Cardiotonic Agents; Heart Failure; Humans; Milrinone; Phosphodiesterase Inhibitors; Pyrazines; Quality of Life; Quinolines | 1999 |
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamole; DNA Primers; Gene Expression Regulation, Enzymologic; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Microglia; Multiple Sclerosis; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrazines; Pyrrolidinones; Quinolines; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Tetrazoles; Theophylline; Tumor Necrosis Factor-alpha; Vinca Alkaloids; Xanthines | 1999 |
Pimobendan inhibits the activation of transcription factor NF-kappaB: a mechanism which explains its inhibition of cytokine production and inducible nitric oxide synthase.
Topics: Amrinone; Animals; Cardiotonic Agents; Colforsin; Cytokines; Humans; Interleukin-1; Luciferases; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Pyrazines; Pyridazines; Quinolines; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |