veratrine has been researched along with 1-3-dipropyl-8-(4-sulfophenyl)xanthine* in 1 studies
1 other study(ies) available for veratrine and 1-3-dipropyl-8-(4-sulfophenyl)xanthine
Article | Year |
---|---|
N6-cyclohexyladenosine inhibits veratridine-stimulated 22Na uptake by rat brain synaptosomes.
The effect of the stable adenosine analogue, N6-cyclohexyladenosine, on 22Na uptake by rat brain synaptosomes stimulated by veratridine was investigated. In the presence of N6-cyclohexyladenosine, both the initial rate and the maximum sodium uptake were decreased. The inhibitory effect of N6-cyclohexyladenosine on sodium uptake by synaptosomes after 5 s of incubation with 22Na was concentration-dependent, antagonized by 1,3-dipropyl-8-p-sulfophenylxanthine, and attenuated by increasing the concentration of veratridine. The possibility that the adenosine analogue, by activating a xanthine-sensitive adenosine receptor, can operate inhibition of the voltage-dependent sodium channels is discussed. Topics: Adenosine; Animals; Brain; Osmolar Concentration; Purinergic Antagonists; Rats; Sodium; Sodium Radioisotopes; Synaptosomes; Time Factors; Veratridine; Veratrine; Xanthines | 1988 |