Page last updated: 2024-08-17

veratridine and saxitoxin

veratridine has been researched along with saxitoxin in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (43.55)	18.7374
1990's	17 (27.42)	18.2507
2000's	16 (25.81)	29.6817
2010's	1 (1.61)	24.3611
2020's	1 (1.61)	2.80

Authors

Authors	Studies
Ritchie, JM	1
Catterall, WA	3
Smythies, JR	2
Podleski, TR; Sastre, A	1
Birkbeck, TH; Gallacher, S	1
Izumi, F; Kobayashi, H; Mita, T; Murai, Y; Sashihara, S; Tsuji, S; Yanagihara, N	1
Dorey, ML; Jellett, JF; Lawrence, JF; Marks, LJ; Stewart, JE; Watson-Wright, W	1
Alfonso, A; Botana, LM; Bujan, MJ; Cavado, A; de la Cruz, LF; Louzao, MC; Vieytes, MR	1
Couraud, F; Dargent, B	1
Corbett, AM; Krueger, BK	1
Arnaudeau, S; Dacquet, C; Jmari, K; Martin, C; Mironneau, C; Mironneau, J; Rakotoarisoa, L; Sayet, I	1
Arita, M; Izumi, F; Satake, M; Uezono, Y; Wada, A; Yanagawa, Y	1
Bevan, S; Chiu, SY; Gray, PT; Ritchie, JM	1
Wang, GK	1
Berwald-Netter, Y; Couraud, F; Koulakoff, A; Martin-Moutot, N	1
Harris, RA; Hunt, WA; Mullin, MJ	1
Catterall, WA; Feller, DJ; Messner, DJ; Scheuer, T	1
Garber, SS; Miller, C	1
Abe, T; Satake, M; Yanagawa, Y	1
Daly, JW; Gusovsky, F; McNeal, ET	1
Catterall, WA; Sherman, SJ	1
Colwell, RR; Kogure, K; Simidu, U; Tamplin, ML	1
Chang, CC; Hong, SJ	1
Ulbricht, W	1
Goldin, SM; Hess, EJ; Rhoden, V	1
Catterall, WA; Risk, M	1
Catterall, WA; Tamkun, MM	1
Albuquerque, EX; Eldefrawi, ME; Matthews, JC; Warnick, JE	1
Catterall, WA; Talvenheimo, JA; Tamkun, MM	2
Catterall, WA; Jacoby, K; Lawrence, JC; Messner, DJ; Sherman, SJ	1
Baumgold, J; Parent, JB; Spector, I	1
Izumi, F; Mita, T; Murai, Y; Sashihara, S; Yanagihara, N	1
Corbett, AM; Vander Klok, MA	1
Stefani, MR; Wachtel, RE; Yorek, MA	1
Kobayashi, H; Niina, H; Urabe, M; Wada, A; Yamamoto, R; Yanagita, T; Yuhi, T	1
Kobayashi, H; Wada, A; Yamamoto, R; Yanagita, T; Yokoo, H; Yuhi, T	1
Kobayashi, H; Wada, A; Yamamoto, R; Yanagita, T; Yokoo, H	1
Hayashi, S; Itoh, Y; Kimura, K; Shimidzu, T; Tatsumi, S; Ukai, Y; Yoshikuni, Y	1
Clausen, T; Harrison, AP; Nielsen, OB	1
Díaz-Trelles, R; Fernández-Sánchez, MT; Novelli, A; Puia, G	1
Kobayashi, H; Minami, S; Shiraishi, S; Wada, A; Yamamoto, R; Yanagita, T; Yokoo, H	1
Iwaoka, WT; Shimojo, RY	1
Baptista de Sousa, JM; Botana, LM; Leira, F; Louzao, MC; Vieytes, MR	1
Kobayashi, H; Shibuya, I; Shiraishi, S; Toyohira, Y; Uezono, Y; Wada, A; Yamamoto, R; Yanagita, T; Yokoo, H	1
Bonifácio, MJ; Cunha, RA; Parada, A; Patmore, L; Sheridan, RD; Soares-da-Silva, P	1
Alcayaga, C; Chen, Z; Marban, E; O'Rourke, B; Suarez-Isla, BA; Tomaselli, G	1
Izumi, F; Kajiwara, K; Nakashima, Y; Wada, A; Yanagihara, N; Yanagita, T	1
Buenaventura, E; Graham, D; Li, GH; Nicholson, RA	1
Kobayashi, H; Minami, S; Saitoh, T; Shiraishi, S; Takasaki, M; Wada, A; Yanagita, T; Yokoo, H	1
Botana, LM; Garcia Cabado, A; Louzao, MC; Rodriguez Vieytes, M; Vieites Baptista De Sousa, JM	1
Calamari, D; Neilan, BA; Pomati, F; Rossetti, C	1
David, LS; Nicholson, RA	1
Antunes, E; Arantes, EC; Baracat, JS; De Nucci, G; Teixeira, CE	1
Chan, NW; Hamilton, MG; Hayden, LJ; Lee, WE; Moore, DM; Moore, GJ; Roy, SS	1
Botana, LM; Cagide, E; Fuwa, H; Louzao, MC; Sasaki, M; Vieytes, MR; Yasumoto, T	1
Berger, A; Hungerford, J; Manger, R; Woodle, D	1
Hegyi, B; Komáromi, I; Nánási, PP; Szentandrássy, N	1
Chinain, M; Darius, HT; Viallon, J	1

Reviews

5 review(s) available for veratridine and saxitoxin

Article	Year
A pharmacological approach to the structure of sodium channels in myelinated axons. Annual review of neuroscience, 1979, Volume: 2 Topics: Aconitine; Action Potentials; Anesthetics, Local; Animals; Anura; Batrachotoxins; Benzocaine; Binding Sites; Chemical Phenomena; Chemistry; Decapodiformes; Ion Channels; Lidocaine; Molecular Conformation; Nerve Fibers, Myelinated; Ranvier's Nodes; Saxitoxin; Tetrodotoxin; Veratridine	1979
The developmental regulation of TTX-sensitive sodium channels in rat skeletal muscle in vivo and in vitro. Society of General Physiologists series, 1985, Volume: 39 Topics: Acetylcholine; Amphibian Proteins; Animals; Bupivacaine; Calcimycin; Carrier Proteins; Denervation; Electrophysiology; Ion Channels; Muscle Development; Neuromuscular Junction; Rats; Receptors, Cholinergic; Sarcolemma; Saxitoxin; Scorpion Venoms; Tetrodotoxin; Veratridine	1985
Ionic channels through the axon membrane (a review). Biophysics of structure and mechanism, 1974, Oct-28, Volume: 1, Issue:1 Topics: Animals; Axons; Biological Transport; Cell Membrane Permeability; Decapodiformes; Electric Stimulation; Kinetics; Membrane Potentials; Neural Conduction; Potassium; Pronase; Ranvier's Nodes; Receptors, Drug; Saxitoxin; Seawater; Sodium; Tetraethylammonium Compounds; Tetrodotoxin; Veratridine	1974
Neurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Annual review of pharmacology and toxicology, 1980, Volume: 20 Topics: Aconitine; Animals; Batrachotoxins; Chemical Phenomena; Chemistry; Humans; Ion Channels; Lipids; Membranes; Neurotoxins; Receptors, Drug; Saxitoxin; Scorpion Venoms; Sodium; Solubility; Structure-Activity Relationship; Tetrodotoxin; Veratridine	1980
Selectivity problems with drugs acting on cardiac Na⁺ and Ca²⁺ channels. Current medicinal chemistry, 2013, Volume: 20, Issue:20 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Batrachotoxins; Calcium Channels, L-Type; Humans; Myocardium; NAV1.5 Voltage-Gated Sodium Channel; Protein Binding; Saxitoxin; Tetrodotoxin; Veratridine	2013

Other Studies

57 other study(ies) available for veratridine and saxitoxin

Article	Year
Neurotoxins as allosteric modifiers of voltage-sensitive sodium channels. Advances in cytopharmacology, 1979, Volume: 3 Topics: Aconitine; Allosteric Regulation; Animals; Batrachotoxins; Binding Sites; Diterpenes; Electricity; Fishes; Ion Channels; Mice; Neurotoxins; Permeability; Saxitoxin; Scorpions; Sea Anemones; Tetrodotoxin; Veratridine	1979
A model of the molecular structure of part of the sodium channel. Advances in cytopharmacology, 1979, Volume: 3 Topics: Aconitine; Amino Acid Sequence; Animals; Batrachotoxins; Fishes; Ion Channels; Models, Biological; Models, Molecular; Saxitoxin; Scorpions; Tetrodotoxin; Veratridine	1979
A simplified model of the molecular structure of the sodium channel. The Alabama journal of medical sciences, 1978, Volume: 15, Issue:4 Topics: Aconitine; Amino Acid Sequence; Animals; Batrachotoxins; Ions; Models, Molecular; Models, Structural; Neurotoxins; Proteins; Saxitoxin; Scorpions; Sodium; Tetrodotoxin; Veratridine	1978
Pharmacologic characterization of the Na+ ionophores in L6 myotubes. Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:4 Topics: Action Potentials; Cell Differentiation; Cells, Cultured; Ionophores; Muscles; Saxitoxin; Sodium; Tetrodotoxin; Time Factors; Toxins, Biological; Veratridine	1976
Activation and inhibition of the action potential Na+ ionophore of cultured rat muscle cells by neurotoxins. Biochemical and biophysical research communications, 1976, Jan-12, Volume: 68, Issue:1 Topics: Action Potentials; Batrachotoxins; Cell Fusion; Cell Line; Ionophores; Muscles; Saxitoxin; Sodium; Tetrodotoxin; Veratridine; Veratrine	1976
A tissue culture assay for direct detection of sodium channel blocking toxins in bacterial culture supernates. FEMS microbiology letters, 1992, Apr-01, Volume: 71, Issue:1 Topics: Animals; Bacterial Toxins; Biological Assay; Culture Media; Mice; Neuroblastoma; Ouabain; Saxitoxin; Sodium Channels; Tetrodotoxin; Tumor Cells, Cultured; Veratridine	1992
Overproduction of voltage-dependent Na+ channels in the developing brain of genetically seizure-susceptible E1 mice. Neuroscience, 1992, Volume: 48, Issue:2 Topics: Aging; Animals; Blotting, Northern; Brain; Cerebral Cortex; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Organ Specificity; Poly A; RNA; RNA, Messenger; Saxitoxin; Seizures; Sodium; Sodium Channels; Synaptic Membranes; Tetrodotoxin; Veratridine	1992
Paralytic shellfish poison (saxitoxin family) bioassays: automated endpoint determination and standardization of the in vitro tissue culture bioassay, and comparison with the standard mouse bioassay. Toxicon : official journal of the International Society on Toxinology, 1992, Volume: 30, Issue:10 Topics: Animals; Biological Assay; Brain Neoplasms; Dinoflagellida; Mice; Neuroblastoma; Ouabain; Saxitoxin; Shellfish; Tumor Cells, Cultured; Veratridine	1992
Changes in rat mast cell responses in sodium-free media. Lack of demonstrable sodium channel activity. Agents and actions, 1991, Volume: 33, Issue:1-2 Topics: Animals; Calcimycin; Calcium; Histamine Release; Mast Cells; Rats; Saxitoxin; Sodium; Sodium Channels; Sucrose; Veratridine	1991
Down-regulation of voltage-dependent sodium channels initiated by sodium influx in developing neurons. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:15 Topics: Amphibian Proteins; Amphotericin B; Animals; Brain; Carrier Proteins; Cells, Cultured; Kinetics; Monensin; Neurons; Rats; Saxitoxin; Sodium; Sodium Channels; Tetrodotoxin; Veratridine	1990
Isolation of two saxitoxin-sensitive sodium channel subtypes from rat brain with distinct biochemical and functional properties. The Journal of membrane biology, 1990, Volume: 117, Issue:2 Topics: Amphibian Proteins; Animals; Batrachotoxins; Brain; Carrier Proteins; Chromatography; Electric Conductivity; Rats; Saxitoxin; Scorpion Venoms; Sodium Channels; Veratridine	1990
Identification and properties of voltage-sensitive sodium channels in smooth muscle cells from pregnant rat myometrium. Molecular pharmacology, 1990, Volume: 38, Issue:5 Topics: Action Potentials; Amiloride; Animals; Binding Sites; Cell Membrane; Cell Separation; Electric Conductivity; Female; Isradipine; Muscle, Smooth; Myometrium; Pregnancy; Pyridines; Radioligand Assay; Rats; Rats, Inbred Strains; Saxitoxin; Sodium Channels; Tetrodotoxin; Veratridine	1990
Conotoxin GIIIA: selective inhibition of 22Na influx via voltage-dependent Na channels in adrenal medullary cells. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:3 Topics: Adrenal Medulla; Animals; Calcium Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Conotoxins; Peptides, Cyclic; Receptors, Nicotinic; Saxitoxin; Sodium Channels; Sodium Radioisotopes; Veratridine	1990
The presence of voltage-gated sodium, potassium and chloride channels in rat cultured astrocytes. Proceedings of the Royal Society of London. Series B, Biological sciences, 1985, Sep-23, Volume: 225, Issue:1240 Topics: Animals; Astrocytes; Brain Chemistry; Cells, Cultured; Cerebral Cortex; Chlorides; Ion Channels; Membrane Potentials; Rats; Rats, Inbred Strains; Saxitoxin; Veratridine	1985
The long-term excitability of myelinated nerve fibres in the transected frog sciatic nerve. The Journal of physiology, 1985, Volume: 368 Topics: Action Potentials; Animals; Axons; Denervation; Ion Channels; Nerve Degeneration; Potassium; Rana pipiens; Ranvier's Nodes; Saxitoxin; Sciatic Nerve; Sodium; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Time Factors; Veratridine	1985
Neurotoxin-sensitive sodium channels in neurons developing in vivo and in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:1 Topics: Animals; Brain; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Ion Channels; Kinetics; Mice; Neurons; Neurotoxins; Pregnancy; Saxitoxin; Scorpion Venoms; Sodium; Tetrodotoxin; Time Factors; Veratridine	1986
Ionizing radiation alters the properties of sodium channels in rat brain synaptosomes. Journal of neurochemistry, 1986, Volume: 47, Issue:2 Topics: Animals; Batrachotoxins; Brain; Electrons; Fluorescence Polarization; Gamma Rays; Ion Channels; Kinetics; Male; Radiation, Ionizing; Rats; Rats, Inbred Strains; Saxitoxin; Sodium; Sodium Radioisotopes; Synaptic Membranes; Synaptosomes; Veratridine	1986
Functional properties of rat brain sodium channels lacking the beta 1 or beta 2 subunit. The Journal of biological chemistry, 1986, Nov-15, Volume: 261, Issue:32 Topics: Amphibian Proteins; Animals; Brain; Carrier Proteins; Ion Channels; Kinetics; Liposomes; Macromolecular Substances; Membrane Proteins; Molecular Weight; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Saxitoxin; Sodium; Veratridine	1986
Single Na+ channels activated by veratridine and batrachotoxin. The Journal of general physiology, 1987, Volume: 89, Issue:3 Topics: Animals; Batrachotoxins; In Vitro Techniques; Ion Channels; Lipid Bilayers; Rats; Sarcolemma; Saxitoxin; Sodium; Tetrodotoxin; Veratridine; Veratrine	1987
Mu-conotoxins share a common binding site with tetrodotoxin/saxitoxin on eel electroplax Na channels. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1987, Volume: 7, Issue:5 Topics: Aconitine; Animals; Binding Sites; Binding, Competitive; Conotoxins; Electric Organ; Electrophorus; Ion Channels; Kinetics; Lidocaine; Mollusk Venoms; Saxitoxin; Sodium; Tetrodotoxin; Veratridine	1987
Stimulation of phosphoinositide breakdown in brain synaptoneurosomes by agents that activate sodium influx: antagonism by tetrodotoxin, saxitoxin, and cadmium. Molecular pharmacology, 1987, Volume: 32, Issue:4 Topics: Alkaloids; Animals; Batrachotoxins; Brain; Cadmium; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Ion Channels; Phosphatidylinositols; Saxitoxin; Scorpion Venoms; Sodium; Synaptosomes; Tetrodotoxin; Veratridine	1987
A tissue culture assay for tetrodotoxin, saxitoxin and related toxins. Toxicon : official journal of the International Society on Toxinology, 1988, Volume: 26, Issue:2 Topics: Animals; Biological Assay; Cell Line; Marine Toxins; Mice; Ouabain; Saxitoxin; Tetrodotoxin; Tumor Cells, Cultured; Veratridine	1988
Pharmacological identification of saxitoxin-like toxins in the cultured purple clam, Hiatula diphos. Toxicon : official journal of the International Society on Toxinology, 1986, Volume: 24, Issue:8 Topics: Animals; Bivalvia; Crotalid Venoms; In Vitro Techniques; Membrane Potentials; Mice; Muscle Contraction; Neuromuscular Junction; Saxitoxin; Tetrodotoxin; Veratridine	1986
Molecular characterization, reconstitution, and "transport-specific fractionation" of the saxitoxin binding protein/Na+ gate of mammalian brain. Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:11 Topics: Amphibian Proteins; Animals; Brain Chemistry; Carrier Proteins; Cattle; Ion Channels; Liposomes; Membrane Proteins; Neurilemma; Saxitoxin; Synaptosomes; Tetrodotoxin; Veratridine	1980
Toxin T4(6) from Ptychodiscus brevis (formerly Gymnodinium breve) enhances activation of voltage-sensitive sodium channels by veratridine. Molecular pharmacology, 1981, Volume: 19, Issue:2 Topics: Cells, Cultured; Dinoflagellida; Drug Synergism; Ion Channels; Kinetics; Marine Toxins; Neoplasms, Experimental; Neuroblastoma; Saxitoxin; Sodium; Veratridine; Veratrine	1981
Reconstitution of the voltage-sensitive sodium channel of rat brain from solubilized components. The Journal of biological chemistry, 1981, Nov-25, Volume: 256, Issue:22 Topics: Amphibian Proteins; Animals; Brain; Carrier Proteins; Drug Stability; Ion Channels; Kinetics; Liposomes; Membrane Potentials; Rats; Saxitoxin; Sodium; Synaptosomes; Veratridine	1981
Characterization of the electrogenic sodium channel from rat brain membranes using neurotoxin-dependent 22Na uptake. Membrane biochemistry, 1981, Volume: 4, Issue:2 Topics: Action Potentials; Animals; Batrachotoxins; Brain; Diterpenes; Female; Ion Channels; Male; Membranes; Muscles; Rats; Saxitoxin; Sodium; Tetrodotoxin; Toxins, Biological; Veratridine	1981
Reconstitution of neurotoxin-stimulated sodium transport by the voltage-sensitive sodium channel purified from rat brain. The Journal of biological chemistry, 1982, Oct-25, Volume: 257, Issue:20 Topics: Amphibian Proteins; Animals; Brain; Carrier Proteins; Electric Stimulation; Ion Channels; Octoxynol; Polyethylene Glycols; Rats; Saxitoxin; Sodium; Temperature; Tetrodotoxin; Time Factors; Veratridine	1982
Tetrodotoxin-sensitive sodium channels in rat muscle cells developing in vitro. The Journal of biological chemistry, 1983, Feb-25, Volume: 258, Issue:4 Topics: Animals; Cells, Cultured; Female; Ion Channels; Muscle Contraction; Muscle Development; Muscles; Pregnancy; Rats; Saxitoxin; Scorpion Venoms; Sodium; Tetrodotoxin; Veratridine	1983
Development of sodium channels during differentiation of chick skeletal muscle in culture. II. 22Na+ uptake and electrophysiological studies. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1983, Volume: 3, Issue:5 Topics: Animals; Batrachotoxins; Biological Transport, Active; Cell Differentiation; Cells, Cultured; Chick Embryo; Ion Channels; Kinetics; Muscles; Saxitoxin; Scorpion Venoms; Sodium; Tetrodotoxin; Veratridine	1983
The sodium channel from rat brain. Reconstitution of neurotoxin-activated ion flux and scorpion toxin binding from purified components. The Journal of biological chemistry, 1984, Feb-10, Volume: 259, Issue:3 Topics: Amphibian Proteins; Animals; Brain; Carrier Proteins; Cell Membrane; Ion Channels; Kinetics; Neurotoxins; Rats; Saxitoxin; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine	1984
Differential up-regulation of voltage-dependent Na+ channels induced by phenytoin in brains of genetically seizure-susceptible (E1) and control (ddY) mice. Neuroscience, 1994, Volume: 62, Issue:3 Topics: Amphibian Proteins; Animals; Carrier Proteins; Cerebral Cortex; Epilepsy; Mice; Mice, Neurologic Mutants; Nerve Tissue Proteins; Phenytoin; RNA, Messenger; Saxitoxin; Sodium Channels; Synaptosomes; Tetrodotoxin; Up-Regulation; Veratridine	1994
Sodium channel subtypes in the rat display functional differences in the presence of veratridine. Biochemical and biophysical research communications, 1994, Mar-30, Volume: 199, Issue:3 Topics: Animals; Brain; Electric Conductivity; Heart; Heart Ventricles; Ion Channel Gating; Lipid Bilayers; Membrane Potentials; Muscles; Organ Specificity; Probability; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Sarcolemma; Saxitoxin; Sodium Channels; Veratridine	1994
Elevated levels of glucose and L-fucose reduce 22Na+ uptake and whole cell Na+ current in cultured neuroblastoma cells. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: Animals; Cell Division; Cell Line; Electric Stimulation; Fucose; Glucose; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Ouabain; Saxitoxin; Sodium; Sodium Channels; Sodium Radioisotopes; Tumor Cells, Cultured; Veratridine	1994
Protein kinase C-mediated down-regulation of voltage-dependent sodium channels in adrenal chromaffin cells. Journal of neurochemistry, 1996, Volume: 66, Issue:3 Topics: Adrenal Glands; Animals; Cattle; Cells, Cultured; Chromaffin System; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Electrophysiology; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Saxitoxin; Sodium Channels; Tetradecanoylphorbol Acetate; Veratridine	1996
Up-regulation of functional voltage-dependent sodium channels by insulin in cultured bovine adrenal chromaffin cells. Journal of neurochemistry, 1996, Volume: 67, Issue:4 Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Chromaffin Cells; Cycloheximide; Dichlororibofuranosylbenzimidazole; Dinoflagellida; Drug Synergism; Electrophysiology; Epinephrine; Insulin; Insulin-Like Growth Factor I; Kinetics; Marine Toxins; Norepinephrine; Ouabain; Oxocins; Receptor, Insulin; Receptors, Nicotinic; Saxitoxin; Sodium; Sodium Channels; Transcription, Genetic; Up-Regulation; Veratridine	1996
Up-regulation of sodium channel subunit mRNAs and their cell surface expression by antiepileptic valproic acid: activation of calcium channel and catecholamine secretion in adrenal chromaffin cells. Journal of neurochemistry, 1997, Volume: 68, Issue:4 Topics: Animals; Anticonvulsants; Blotting, Northern; Calcium; Calcium Channel Agonists; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Gene Expression Regulation; Ion Channel Gating; Marine Toxins; Membrane Proteins; Neurotoxins; Oxocins; Potassium; Receptors, Nicotinic; RNA, Messenger; Saxitoxin; Sodium Channels; Tritium; Up-Regulation; Valproic Acid; Veratridine	1997
Blockade of voltage-sensitive sodium channels by NS-7, a novel neuroprotective compound, in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:5 Topics: Aconitine; Analysis of Variance; Animals; Batrachotoxins; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Heart; Injections, Intravenous; Male; Myocardium; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pyrimidines; Rats; Rats, Wistar; Saxitoxin; Sodium Channels; Synaptosomes; Veratridine	1997
Role of Na(+)-K+ pump and Na+ channel concentrations in the contractility of rat soleus muscle. The American journal of physiology, 1997, Volume: 272, Issue:5 Pt 2 Topics: Aconitine; Age Factors; Animals; Electric Stimulation; Female; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Ouabain; Potassium Deficiency; Protein Binding; Rats; Rats, Wistar; Saxitoxin; Sodium Channel Agonists; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Veratridine	1997
Terfenadine prevents NMDA receptor-dependent and -independent toxicity following sodium channel activation. Brain research, 1999, Sep-25, Volume: 842, Issue:2 Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Glutamic Acid; Neurons; Pyrilamine; Rats; Receptors, N-Methyl-D-Aspartate; Saxitoxin; Sodium Channels; Terfenadine; Tetrodotoxin; Veratridine	1999
Short- and long-term differential effects of neuroprotective drug NS-7 on voltage-dependent sodium channels in adrenal chromaffin cells. British journal of pharmacology, 2000, Volume: 131, Issue:4 Topics: Animals; Brefeldin A; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Cycloheximide; Neuroprotective Agents; Pyrimidines; RNA, Messenger; Saxitoxin; Sodium Channels; Veratridine	2000
A rapid hemolysis assay for the detection of sodium channel-specific marine toxins. Toxicology, 2000, Nov-23, Volume: 154, Issue:1-3 Topics: Animals; Ciguatoxins; Enzyme Inhibitors; Erythrocytes; Fishes, Poisonous; Hemolysis; Male; Marine Toxins; Ouabain; Saxitoxin; Sodium Channels; Tetrodotoxin; Tilapia; Veratridine	2000
A fluorimetric method based on changes in membrane potential for screening paralytic shellfish toxins in mussels. Analytical biochemistry, 2001, Feb-15, Volume: 289, Issue:2 Topics: Animals; Biological Assay; Bivalvia; Chromatography, High Pressure Liquid; Fluorometry; Food Contamination; Gramicidin; Humans; Marine Toxins; Membrane Potentials; Mice; Neuroblastoma; Radioligand Assay; Reproducibility of Results; Saxitoxin; Sensitivity and Specificity; Shellfish; Spectrometry, Fluorescence; Time Factors; Tumor Cells, Cultured; Veratridine	2001
Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels. British journal of pharmacology, 2001, Volume: 132, Issue:7 Topics: Animals; Binding, Competitive; Brefeldin A; Calcimycin; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calpain; Carbazoles; Cattle; Cells, Cultured; Chromaffin Cells; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Hydroquinones; Indoles; Ionophores; Marine Toxins; Oxocins; Protein Subunits; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Saxitoxin; Scorpion Venoms; Sodium; Sodium Channels; Thapsigargin; Time Factors; Tritium; Veratridine	2001
Interaction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine. Epilepsia, 2001, Volume: 42, Issue:5 Topics: Animals; Anticonvulsants; Batrachotoxins; Brain; Carbamazepine; Cerebral Cortex; Dibenzazepines; Mice; Patch-Clamp Techniques; Saxitoxin; Sodium; Sodium Channels; Synaptosomes; Tumor Cells, Cultured; Veratridine	2001
A "minimal" sodium channel construct consisting of ligated S5-P-S6 segments forms a toxin-activatable ionophore. The Journal of biological chemistry, 2002, Jul-05, Volume: 277, Issue:27 Topics: Animals; Cell Line; Gramicidin; Humans; Ionophores; Membrane Potentials; Models, Molecular; Muscle, Skeletal; Peptide Fragments; Protein Conformation; Rats; Saxitoxin; Sodium; Sodium Channels; Spectrometry, Fluorescence; Toxins, Biological; Transfection; Veratridine	2002
Differential effects of short and prolonged exposure to carvedilol on voltage-dependent Na(+) channels in cultured bovine adrenal medullary cells. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1 Topics: Adrenal Medulla; Adrenergic beta-Antagonists; Animals; Blotting, Northern; Calcium; Carbazoles; Carvedilol; Catecholamines; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Kinetics; Propanolamines; Protein Synthesis Inhibitors; RNA, Messenger; Saxitoxin; Sodium; Sodium Channels; Veratridine	2002
A rapid and sensitive assay for paralytic shellfish poison (PSP) toxins using mouse brain synaptoneurosomes. Toxicon : official journal of the International Society on Toxinology, 2002, Volume: 40, Issue:6 Topics: Animals; Biological Assay; Dose-Response Relationship, Drug; Fluorescent Dyes; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Mollusca; Reproducibility of Results; Rhodamines; Saxitoxin; Sensitivity and Specificity; Shellfish; Synaptosomes; Veratridine	2002
Differential effects of bupivacaine enantiomers, ropivacaine and lidocaine on up-regulation of cell surface voltage-dependent sodium channels in adrenal chromaffin cells. Brain research, 2003, Mar-21, Volume: 966, Issue:2 Topics: Amides; Anesthetics, Local; Animals; Blotting, Northern; Bupivacaine; Cattle; Cells, Cultured; Chromaffin Cells; Enzyme Inhibitors; Lidocaine; Ouabain; Potassium Channel Blockers; Ropivacaine; Saxitoxin; Scorpion Venoms; Sodium; Sodium Channels; Transcription, Genetic; Tritium; Up-Regulation; Veratridine	2003
A fluorimetric microplate assay for detection and quantitation of toxins causing paralytic shellfish poisoning. Chemical research in toxicology, 2003, Volume: 16, Issue:4 Topics: Animals; Biological Assay; Bivalvia; Dinoflagellida; Fluorometry; Food Contamination; Gramicidin; Humans; Male; Marine Toxins; Membrane Potentials; Mice; Paralysis; Reproducibility of Results; Saxitoxin; Sensitivity and Specificity; Shellfish; Shellfish Poisoning; Sodium Channels; Time Factors; Tumor Cells, Cultured; Veratridine	2003
Effects of saxitoxin (STX) and veratridine on bacterial Na+ -K+ fluxes: a prokaryote-based STX bioassay. Applied and environmental microbiology, 2003, Volume: 69, Issue:12 Topics: Bacteriolysis; Biological Assay; Cyanobacteria; Luminescent Measurements; Potassium; Potassium Channels; Prokaryotic Cells; Saxitoxin; Sodium; Sodium Channels; Veratridine; Vibrio	2003
Quantitation of paralytic shellfish toxins using mouse brain synaptoneurosomes. Chemosphere, 2004, Volume: 55, Issue:10 Topics: Animals; Bivalvia; Brain; Fluorescence; Membrane Potentials; Mice; Mice, Inbred Strains; Rhodamines; Saxitoxin; Synaptosomes; Veratridine; Veratrine; Zooplankton	2004
Effects of beta-adrenoceptor antagonists in the neural nitric oxide release induced by electrical field stimulation and sodium channel activators in the rabbit corpus cavernosum. European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2 Topics: Aconitine; Adrenergic beta-Antagonists; Animals; Atenolol; Betaxolol; Binding Sites; Electric Stimulation; In Vitro Techniques; Insect Proteins; Male; Metoprolol; Muscle Relaxation; Neurotoxins; Nitric Oxide; Penis; Propanolamines; Propranolol; Rabbits; Saxitoxin; Scorpion Venoms; Sodium Channel Agonists; Tetrodotoxin; Veratridine	2005
Hinge peptide combinatorial libraries for inhilbitors of botulinum neurotoxins and saxitoxin: deconvolution strategy. Molecular diversity, 2006, Volume: 10, Issue:1 Topics: Biological Assay; Botulinum Toxins; Botulinum Toxins, Type A; Cell Survival; Combinatorial Chemistry Techniques; Enzyme Inhibitors; Humans; Ligands; Metalloendopeptidases; Neuroblastoma; Ouabain; Peptide Fragments; Peptide Library; Protease Inhibitors; Saxitoxin; Veratridine; Zinc	2006
The sodium channel of human excitable cells is a target for gambierol. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2006, Volume: 17, Issue:5-6 Topics: Calcium; Cell Polarity; Ciguatoxins; Ethers, Cyclic; Humans; Membrane Potentials; Neuroblastoma; Neurons; Polycyclic Compounds; Saxitoxin; Sodium Channels; Sodium-Calcium Exchanger; Tumor Cells, Cultured; Veratridine	2006
Flow cytometric detection of saxitoxins using fluorescent voltage-sensitive dyes. Analytical biochemistry, 2007, Jul-15, Volume: 366, Issue:2 Topics: Animals; Cell Line, Tumor; Flow Cytometry; Fluorescence; Fluorescent Dyes; Mytilus edulis; Saxitoxin; Veratridine	2007
Revisiting the Neuroblastoma Cell-Based Assay (CBA-N2a) for the Improved Detection of Marine Toxins Active on Voltage Gated Sodium Channels (VGSCs). Toxins, 2020, 04-27, Volume: 12, Issue:5 Topics: Animals; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Ciguatoxins; Dose-Response Relationship, Drug; Fishes; Limit of Detection; Marine Toxins; Mice; Neuroblastoma; Neurons; Ouabain; Oxocins; Reproducibility of Results; Saxitoxin; Time Factors; Veratridine; Voltage-Gated Sodium Channel Agonists; Voltage-Gated Sodium Channels	2020