verapamil and wortmannin

verapamil has been researched along with wortmannin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's5 (41.67)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, D; Goh, WH; Soh, CK; Wang, H1
Goh, EL; Graichen, R; Lobie, PE; Norstedt, G; Pircher, TJ; Wood, TJ1
Gilani, AH; Rashid, F; Saeed, SA; Shah, BH1
Cheema, M; Connor, JD; Gilani, AH; Rasheed, H; Rizvi, Z; Saeed, SA1
Asano, Y; Ishibashi, S; Miyata, Y; Muto, S; Okada, K1
Hori, M; Karaki, H; Ozaki, H; Tasaki, K; Wakabayashi, I1
Seidler, U; Tuo, BG; Wen, GR1
Bechtel, LK; Haverstick, DM; Holstege, CP1
Escott, GM; Jacobus, AP; Loss, ES1
Gomaa, OM; Linz, JE; Selim, NS1

Other Studies

12 other study(ies) available for verapamil and wortmannin

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma.
    Journal of medicinal chemistry, 2018, 02-22, Volume: 61, Issue:4

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Screening Assays, Antitumor; Heterografts; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Liver Neoplasms; Liver Neoplasms, Experimental; Mice; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2018
Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (signal transducer and activator of transcription-5)-mediated transcription.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: 3T3 Cells; Actin Cytoskeleton; Actins; Androstadienes; Animals; Calcium Channel Blockers; Cell Line; CHO Cells; Cricetinae; Cytoskeleton; DNA-Binding Proteins; DNA, Complementary; Female; Growth Hormone; Humans; Insulin-Like Growth Factor I; Mice; Microscopy, Electron; Milk Proteins; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Rats; Receptors, Somatotropin; Signal Transduction; STAT5 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Verapamil; Wortmannin

1997
Dopamine potentiation of calcium ionophore, A-23187-induced platelet aggregation.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Androstadienes; Aspirin; Benzophenanthridines; Calcimycin; Calcium; Chlorpromazine; Diltiazem; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; GTP-Binding Proteins; Haloperidol; Homovanillic Acid; Humans; Indomethacin; Ion Transport; Ionophores; Phenanthridines; Phentolamine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Propranolol; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Dopamine; Serotonin; Signal Transduction; Verapamil; Wortmannin

1997
Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore.
    Life sciences, 2001, Oct-26, Volume: 69, Issue:23

    Topics: Adult; Alkaloids; Androstadienes; Benzophenanthridines; Blood Platelets; Calcimycin; Calcium Channel Blockers; Cyproheptadine; Diltiazem; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Estrenes; Female; Genistein; Humans; In Vitro Techniques; Ionophores; Male; Methysergide; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Pyrrolidinones; Second Messenger Systems; Serotonin; Type C Phospholipases; Verapamil; Wortmannin

2001
P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:1

    Topics: Actin Cytoskeleton; Androstadienes; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carcinogens; Chromones; Colchicine; Cyclosporine; Cytochalasin B; Diuretics, Osmotic; Enzyme Inhibitors; Hypertonic Solutions; Kidney Tubules, Proximal; Male; Mannitol; Mice; Mice, Knockout; Microtubules; Morpholines; Naphthalenes; Phorbols; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Wortmannin

2002
Mechanism of human urotensin II-induced contraction in rat aorta.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:4

    Topics: Androstadienes; Animals; Aorta, Thoracic; Butadienes; Calcium; Carbazoles; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Lanthanum; Male; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle Contraction; Myosin Light Chains; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Potassium Chloride; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Thapsigargin; Urotensins; Verapamil; Wortmannin

2004
Phosphatidylinositol 3-kinase is involved in prostaglandin E2-mediated murine duodenal bicarbonate secretion.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:1

    Topics: Androstadienes; Animals; Bicarbonates; Calcium Signaling; Carbazoles; Chromones; Cyclic AMP; Dinoprostone; Duodenum; Flavonoids; Genistein; Imines; Indoles; Intestinal Mucosa; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Sulfonamides; Verapamil; Wortmannin

2007
Verapamil toxicity dysregulates the phosphatidylinositol 3-kinase pathway.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:4

    Topics: Adipocytes; Androstadienes; Animals; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Glucose; Insulin; Mice; Nifedipine; Phosphatidylinositol 3-Kinases; Signal Transduction; Verapamil; Wortmannin

2008
PI3K-dependent actions of insulin and IGF-I on seminiferous tubules from immature rats.
    Pflugers Archiv : European journal of physiology, 2013, Volume: 465, Issue:10

    Topics: Amino Acids; Androstadienes; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Glucose; Insulin; Insulin-Like Growth Factor I; Male; Membrane Potentials; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Seminiferous Tubules; Sertoli Cells; Signal Transduction; Verapamil; Wortmannin

2013
A possible role of Aspergillus niger mitochondrial cytochrome c in malachite green reduction under calcium chloride stress.
    Cell biochemistry and biophysics, 2013, Volume: 67, Issue:3

    Topics: Androstadienes; Aspergillus niger; Caco-2 Cells; Calcium Chloride; Cell Survival; Chromatography, High Pressure Liquid; Cytochromes c; Humans; Mass Spectrometry; Mitochondria; NADH, NADPH Oxidoreductases; Rosaniline Dyes; Verapamil; Wortmannin

2013