verapamil has been researched along with warfarin in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (23.91) | 18.7374 |
| 1990's | 9 (9.78) | 18.2507 |
| 2000's | 20 (21.74) | 29.6817 |
| 2010's | 40 (43.48) | 24.3611 |
| 2020's | 1 (1.09) | 2.80 |
| Authors | Studies |
|---|---|
| Gubernator, K; Kansy, M; Senner, F | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Hwang, KK; Mandagere, AK; Thompson, TN | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Briand, X; Faller, B; Lázaro, E; Lowe, PJ | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Arvanites, AC; Benmohamed, R; Chen, T; Ferrante, RJ; Kirsch, DR; Morimoto, RI; Ralay Ranaivo, H; Silverman, RB; Watterson, DM | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Choi, SH; Kazantsev, AG; Khanfar, MA; Quinti, L; Silverman, RB; Wang, H | 1 |
| Alexandrova, AN; Armijo, AL; Czernin, J; Gipson, RM; Jung, ME; Lavie, A; Le, T; Li, Z; Nguyen, HA; Nomme, J; Poddar, S; Radu, CG; Santarsiero, BD; Smith, T; Wang, J | 1 |
| Aguilera-Venegas, B; Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; Lepesheva, GI; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR | 1 |
| Creemer, CN; Dai, M; Davis, DC; Kyei-Baffour, K; Mohammad, H; Seleem, MN; Younis, W | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abdelghany, TM; Bayoumi, SA; Disouky, AM; El-Morsy, A; Elshafeey, A; Mancy, AS; Mayhoub, AS; Mohammad, H; Seleem, MA; Seleem, MN | 1 |
| Abdelghany, TM; Fayed, E; Mayhoub, AS; Mohammad, H; Seleem, MN; Yahia, E | 1 |
| Benavides, R; Cichewicz, RH; Du, L; Kuhn, JG; Li, J; Mooberry, SL; Risinger, AL; Robles, AJ | 1 |
| Abd Rabo Moustafa, MM; Abdelghany, TM; Eissa, IH; Elshafeey, A; Mayhoub, AS; Mohammad, H; Qassem, OA; Seleem, MN; Younis, W | 1 |
| Ghiaty, A; Hagras, M; Hegazy, YA; Mandour, MS; Mayhoub, AS; Mohammad, H; Seleem, MN | 1 |
| Alliston, KR; Bowlin, TL; Butler, MM; Cardinale, SC; Chang, KO; Galasiti Kankanamalage, AC; Groutas, WC; Kim, Y; Rathnayake, AD | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Chreifi, G; Do, HT; Li, H; Poulos, TL; Silverman, RB; Wang, HY | 1 |
| Chibale, K; Egan, TJ; Hunter, R; Joshi, MC; Ndove, J; Nsumiwa, S; Okombo, J; Taylor, D; Wiesner, L | 1 |
| Cescon, DW; Hansen, MD; Hoj, JP; Siddiqui-Jain, A | 1 |
| Eslamimehr, S; Franzblau, SG; Kong, Y; Kurosu, M; Lemieux, MR; Mitachi, K; Park, F; Pressly, JD; Siricilla, S; Wang, Y; Yang, D | 1 |
| Aretz, CD; Hopkins, CR; Vadukoot, AK | 1 |
| Barbero, S; Fairlie, DP; Gupta, PK; Lim, J; Liu, L; Loh, Z; Lucke, AJ; Mak, JYW; McLaughlin, MG; Reid, RC; Sweet, MJ; Tng, J; Wu, KC | 1 |
| Clausen, T; Gliemann, J; Martin, BR | 1 |
| Bauman, JL; Ezri, M; Nazari, J; Tworek, DA | 1 |
| Boddy, AV; Levy, RH | 1 |
| Bruserud, O | 1 |
| Husson, M; Klastersky, J; Petrikkos, G; Van der Auwera, P | 1 |
| Bayliss, J; Buller, N; Fox, K; Rickards, A; Shapiro, L; Urban, P | 1 |
| Hashimoto, K; Kimura, T; Kubota, K; Oguro, K | 1 |
| Hashimoto, K; Kokubun, M; Taira, N | 1 |
| Hashimoto, K; Oguro, K | 1 |
| Junge-Hülsing, G; Schmitt, G; Wagner, H | 1 |
| Juan, H; Kukovetz, WR; Pöch, G | 1 |
| Kosche, F; Lochner, W; Raff, KW | 1 |
| Goto, N | 1 |
| Berman, R; Simonson, E | 1 |
| Hefner, MA; Howe, BB; Winbury, MM | 1 |
| Kaltenbach, M | 1 |
| Yokoyama, H | 1 |
| Osugi, S | 1 |
| Ignat'ev, MV | 1 |
| Lozinskiĭ, LG; Votchal, BE | 1 |
| Seta, K | 1 |
| Brand, E; Dietze, G; Rudolph, W; Wicklmayr, M | 1 |
| Runge, M | 1 |
| Nitz, RE; Schraven, E; Trottnow, D | 1 |
| Simonsen, S | 1 |
| Li, L; Yang, L; Zhang, CL; Zhao, DK; Zhao, GS; Zhuang, FE | 1 |
| Asakawa, N; Ishihama, Y; Oda, Y | 1 |
| Li, L; Zhao, DK; Zhao, GS; Zhuang, FE | 1 |
| Blackshear, JL; Hammill, SC; Kopecky, SL; Litin, SC; Safford, RE | 1 |
| Ding, Y; Lin, B; Zhu, X | 1 |
| Axelsson, H; Floby, E; Granhall, C; Jaksch, Y; Sohlenius-Sternbeck, AK; Svedling, M | 1 |
| Faulkner, MA; Lenz, NJ; Lenz, TL | 1 |
| Bailly, C; Cuevas, C; Kluza, J; Lansiaux, A; Otero, G; Tardy, C; Vanhuyse, M | 1 |
| Elston Lafata, J; Horn, JR; Kaatz, S; Raebel, MA; Schultz, L; Simpkins, J; Smith, DH; Yood, MU | 1 |
| Flitman, S; Tobin, J | 1 |
| Chen, S; Hage, DS; Mallik, R; Yoo, MJ | 1 |
| Baumert, C; Hilgeroth, A | 1 |
| Bradley, DF; Dryfe, RA; Tam, KY; Velický, M | 1 |
| Bernkop-Schnürch, A; Iqbal, J; Sakloetsakun, D | 1 |
| Austin, RP; Barton, P; Wenlock, MC | 1 |
| Behravan, J; Hanafi-Bojd, MY; Iranshahi, M; Kalalinia, F; Mosaffa, F; Tehrani, SO | 1 |
| Baba, K; Hamahata, Y; Iwanaga, K; Kakemi, M; Miyazaki, M; Shibano, M; Taniguchi, M; Yoneda, S | 1 |
| Altman, RB; Garten, Y; Percha, B | 1 |
| Burkina, V; Fedorova, G; Li, ZH; Pickova, J; Randak, T; Zamaratskaia, G; Zlabek, V | 1 |
| Cao, YC; Liang, XL; Liao, ZG; Yang, M; Zhao, GW; Zhao, LJ; Zhu, ML | 1 |
| Becker, RC; Berkowitz, SD; Breithardt, G; Fox, KAA; Halperin, JL; Hankey, GJ; Hellkamp, AS; Lokhnygina, Y; Mahaffey, KW; Nessel, CC; Patel, MR; Piccini, JP; Singer, DE; Washam, JB | 1 |
| Liu, L; Liu, X; Tang, X; Wang, S; Xu, J; Yang, T; Zhang, J | 1 |
9 review(s) available for verapamil and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Discovery of Small Molecule Renal Outer Medullary Potassium (ROMK) Channel Inhibitors: A Brief History of Medicinal Chemistry Approaches To Develop Novel Diuretic Therapeutics.
Topics: Animals; Bee Venoms; Diuretics; Half-Life; Humans; Kidney; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Small Molecule Libraries; Sulfonamides | 2019 |
Interference by antiarrhythmic agents with function of electrical cardiac devices.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Death, Sudden, Cardiac; Digoxin; Drug Interactions; Electric Countershock; Female; Flecainide; Humans; Male; Middle Aged; Pacemaker, Artificial; Prostheses and Implants; Verapamil; Warfarin | 1992 |
Stereoselectivity in pharmacokinetics: a general theory.
Topics: Humans; Mephenytoin; Models, Biological; Pharmacokinetics; Propranolol; Stereoisomerism; Verapamil; Warfarin | 1991 |
Comparison of therapeutic effects of coronary drugs in the USSR.
Topics: Angina Pectoris; Benzoates; Benzyl Compounds; Clinical Trials as Topic; Coronary Disease; Coumarins; Electrocardiography; Ethylenediamines; Exercise Test; Glycolates; Humans; Isoquinolines; Papaverine; Propylamines; Time Factors; United States; USSR; Verapamil | 1971 |
[Therapy of arrhythmia during pregnancy].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biotransformation; Coumarins; Digoxin; Drug Synergism; Female; Fetal Growth Retardation; Fetus; Heparin; Humans; Infant, Newborn; Milk, Human; Pacemaker, Artificial; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Verapamil | 1984 |
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Catheter Ablation; Cerebrovascular Disorders; Diabetes Complications; Digoxin; Diltiazem; Embolism; Humans; Hypertension; Thromboembolism; Verapamil; Warfarin | 1996 |
Potential interactions between exercise and drug therapy.
Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Aspirin; Digoxin; Doxycycline; Exercise; Humans; Insulin; Pharmacokinetics; Theophylline; Tissue Distribution; Verapamil; Warfarin | 2004 |
Recent advances in the development of P-gp inhibitors.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Coumarins; Drug Design; Drug Resistance, Neoplasm; Flavonoids; Humans; Peptides; Propafenone; Propanolamines; Pyrazoles; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Structure-Activity Relationship; Tamoxifen; Terpenes; Verapamil | 2009 |
4 trial(s) available for verapamil and warfarin
| Article | Year |
|---|---|
Lack of effect of warfarin on the restenosis rate or on clinical outcome after balloon coronary angioplasty.
Topics: Adult; Aged; Angioplasty, Balloon; Clinical Trials as Topic; Coronary Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Random Allocation; Recurrence; Verapamil; Warfarin | 1988 |
Comparison of therapeutic effects of coronary drugs in the USSR.
Topics: Angina Pectoris; Benzoates; Benzyl Compounds; Clinical Trials as Topic; Coronary Disease; Coumarins; Electrocardiography; Ethylenediamines; Exercise Test; Glycolates; Humans; Isoquinolines; Papaverine; Propylamines; Time Factors; United States; USSR; Verapamil | 1971 |
Pharmacological effects on coronary haemodynamics. A comparative study between atenolol, verapamil, nifedipine and carbocromen.
Topics: Atenolol; Chromonar; Coronary Circulation; Coronary Disease; Coumarins; Hemodynamics; Humans; Nifedipine; Oxygen Consumption; Propanolamines; Pyridines; Verapamil | 1981 |
Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial).
Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Factor Xa Inhibitors; Female; Humans; Male; Risk Factors; Rivaroxaban; Stroke; Treatment Outcome; Verapamil; Warfarin | 2017 |
80 other study(ies) available for verapamil and warfarin
| Article | Year |
|---|---|
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Inactivation, Metabolic; Liver; Microsomes, Liver; Models, Biological; Permeability; Pharmacokinetics; Rats; Species Specificity | 2002 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Arylsulfanyl pyrazolones block mutant SOD1-G93A aggregation. Potential application for the treatment of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Mice; Pyrazolones; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase | 2011 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors.
Topics: Acetylation; Benzamides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neuroprotective Agents; Sirtuin 2; Structure-Activity Relationship | 2014 |
Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
Topics: Animals; Antineoplastic Agents; Binding Sites; Chemistry, Pharmaceutical; Computer Simulation; Crystallography, X-Ray; Deoxycytidine; Deoxycytidine Kinase; Drug Design; Female; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Microsomes; Phosphorylation; Positron-Emission Tomography; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Stereoisomerism; Thiazoles | 2014 |
Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents.
Topics: Amides; Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Methanol; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2015 |
Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Caco-2 Cells; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Humans; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitriles; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin Resistance | 2015 |
Second-Generation Phenylthiazole Antibiotics with Enhanced Pharmacokinetic Properties.
Topics: Anti-Bacterial Agents; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Hydrazines; Keratinocytes; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2016 |
Phenylthiazole antibiotics: A metabolism-guided approach to overcome short duration of action.
Topics: Anti-Bacterial Agents; Cells, Cultured; Drug Resistance, Bacterial; Drug Stability; Half-Life; Humans; Keratinocytes; Methicillin-Resistant Staphylococcus aureus; Structure-Activity Relationship; Thiazoles | 2017 |
Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Microtubules; Molecular Structure; Steroids; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2017 |
Diphenylurea derivatives for combating methicillin- and vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Carbanilides; Drug Resistance, Bacterial; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2017 |
Investigating the Antibacterial Activity of Biphenylthiazoles against Methicillin- and Vancomycin-Resistant Staphylococcus aureus (MRSA and VRSA).
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Structure-Activity Relationship; Thiazoles; Vancomycin | 2017 |
Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.
Topics: Animals; Antiviral Agents; Aza Compounds; Blood Proteins; Carbamates; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Esters; Humans; Hydrolysis; Mice; Microsomes, Liver; Models, Molecular; Norovirus; Prodrugs; Protein Binding; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Viral Proteins | 2017 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.
Topics: Aminopyridines; Animals; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Fluorobenzenes; Humans; Mice; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Structure-Activity Relationship; Swine; Theophylline; Verapamil | 2017 |
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group Are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice.
Topics: Administration, Oral; Aminopyridines; Aminoquinolines; Animals; Antimalarials; Cell Membrane Permeability; Chloroquine; CHO Cells; Cricetulus; Drug Evaluation, Preclinical; Drug Resistance, Microbial; ERG1 Potassium Channel; Hemeproteins; Humans; Malaria; Male; Mice, Inbred BALB C; Plasmodium berghei; Plasmodium falciparum; Solubility; Structure-Activity Relationship | 2017 |
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.
Topics: Amides; Animals; Cell Line, Tumor; Cell Proliferation; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Microsomes, Liver; Microtubules; Molecular Structure; Neoplasms, Experimental; Polymerization; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship | 2018 |
An antimycobacterial pleuromutilin analogue effective against dormant bacilli.
Topics: Administration, Oral; Animals; Antitubercular Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Diterpenes; Female; Half-Life; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pleuromutilins; Polycyclic Compounds | 2018 |
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates.
Topics: Benzamides; Benzeneacetamides; Biphenyl Compounds; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; THP-1 Cells | 2021 |
Relationships between the exchange of calcium and phosphate in isolated fat-cells.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Calcium; Cell Separation; Dinitrophenols; Glucose; In Vitro Techniques; Male; Oligomycins; Phosphates; Rats; Time Factors; Verapamil; Warfarin | 1975 |
The additive effect of certain drugs on the cyclosporine A inhibition of human T-cell proliferation. Studies using theophyllamine, warfarin, verapamil and dipyridamol.
Topics: Aminophylline; Cell Division; Cells, Cultured; Cyclosporins; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Humans; Lymphocyte Activation; Lymphokines; T-Lymphocyte Subsets; T-Lymphocytes; Time Factors; Verapamil; Warfarin | 1990 |
Influence of various antibiotics on superoxide generation by normal human neutrophils.
Topics: Aminocoumarins; Anti-Bacterial Agents; Calcium; Coumarins; Culture Media; Dose-Response Relationship, Drug; Humans; Neutrophils; Superoxides; Verapamil | 1986 |
Effects of various coronary vasodilators on myocardial oxygen consumption.
Topics: Animals; Benzopyrans; Butyrates; Coronary Circulation; Coumarins; Dicarboxylic Acids; Diethylamines; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Female; Glycolates; Heart; Heart Rate; Isoproterenol; Khellin; Lidoflazine; Male; Myocardium; Nitrobenzenes; Nitroglycerin; Oxygen Consumption; Papaverine; Prenylamine; Pyridines; Triazoles; Vasodilator Agents; Verapamil | 1973 |
Cardiohemodynamic effects of nitroglycerin and several vasodilators.
Topics: Aminophylline; Animals; Blood Pressure; Cardiac Output; Coumarins; Dipyridamole; Female; Glycolates; Heart Rate; Hemodynamics; Male; Morpholines; Nitriles; Nitroglycerin; Nitroso Compounds; Papaverine; Prenylamine; Pyridines; Triazoles; Vasodilator Agents; Verapamil | 1974 |
Quantitative and comparative studies of pharmacological features in the coronary, femoral and renal circulations with different coronary vasodilators.
Topics: Animals; Coronary Vessels; Coumarins; Dicarboxylic Acids; Dipyridamole; Dogs; Female; Femoral Artery; Femoral Vein; Glycolates; Khellin; Lidoflazine; Male; Nitrobenzenes; Nitroglycerin; Papaverine; Prenylamine; Pyridines; Pyrimidines; Renal Artery; Renal Veins; Vasodilator Agents; Verapamil | 1974 |
[On the effect of various cardiac drugs on the connective tissue].
Topics: Animals; Benzoates; Connective Tissue; Coumarins; Dipyridamole; Glycolates; Glycosaminoglycans; Granulation Tissue; Heart; Histological Techniques; Male; Myocardium; Nicotinic Acids; Prenylamine; Propranolol; Rats; Stimulation, Chemical; Sulfur Isotopes; Sympatholytics; Theophylline; Vasodilator Agents; Verapamil | 1967 |
[Influence of cardio- and vasoactive substances on phosphodiesterase activity].
Topics: Animals; Anti-Arrhythmia Agents; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Coronary Vessels; Coumarins; Dipyridamole; Glycolates; Myocardium; Nitriles; Phosphoric Monoester Hydrolases; Propiophenones; Vasodilator Agents; Verapamil | 1969 |
[Influence of extracellular calcium concentration on the effect of coronary dilatators (action mechanism of coronary dilatators)].
Topics: 1-Propanol; Aminophylline; Animals; Benzoates; Calcium; Coronary Vessels; Coumarins; Dicarboxylic Acids; Dipyridamole; Electromagnetic Phenomena; Ethylenediamines; Extracellular Space; Glycolates; Guinea Pigs; Heart Ventricles; Nitrobenzenes; Nitroglycerin; Oxygen; Partial Pressure; Perfusion; Piperazines; Prenylamine; Pyridines; Vasodilator Agents; Verapamil | 1972 |
[Clinical pathophysiological studies on the effects of various coronary vasodilators on myocardial carbohydrate metabolism. 2. Effects of various coronary vasodilators on myocardial carbohydrate metabolism in various diseases].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Glucose; Carbohydrate Metabolism; Coronary Disease; Coumarins; Dipyridamole; Female; Glucose; Glycolates; Heart Valve Diseases; Humans; Isosorbide Dinitrate; Lactates; Male; Middle Aged; Myocardium; Propylamines; Pyruvates; Stimulation, Chemical; Vasodilator Agents; Verapamil; Xanthines | 1972 |
Effect of nitrates and other coronary dilators on large and small coronary vessels: an hypothesis for the mechanism of action of nitrates.
Topics: Aminophylline; Animals; Aorta; Biophysical Phenomena; Biophysics; Blood Circulation; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Electricity; Glycolates; Hemodynamics; Hyperemia; Isoproterenol; Nitrates; Nitroglycerin; Papaverine; Pentaerythritol Tetranitrate; Prenylamine; Propranolol; Vasodilator Agents; Verapamil | 1969 |
[Drug therapy of angina pectoris. Evaluation of various drugs by means of work tests].
Topics: Angina Pectoris; Angiography; Anti-Arrhythmia Agents; Coumarins; Dipyridamole; Electrocardiography; Exercise Test; Glycolates; Humans; Ischemia; Nitriles; Nitroglycerin; Prenylamine; Sympatholytics; Vasodilator Agents; Verapamil | 1970 |
[Clinical physiopathological studies on myocardial oxygen metabolism. 3. Myocardial oxygen metabolism during administration of coronary dilators].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Coronary Disease; Coumarins; Dipyridamole; Female; Gallic Acid; Glycolates; Heart Diseases; Humans; Hypotension; Lung Diseases; Male; Middle Aged; Myocardial Infarction; Myocardium; Oxygen Consumption; Propylamines; Vasodilator Agents; Verapamil; Xanthines | 1971 |
[Clinical pathophysiological studies on coronary circulation. 3. The effects of so-called coronary vasodilator agents on coronary circulation in various diseases].
Topics: Adolescent; Adult; Aged; Benzoates; Benzofurans; Blood Flow Velocity; Blood Pressure; Coronary Disease; Coronary Vessels; Coumarins; Dipyridamole; Female; Glycolates; Heart Rate; Humans; Hypertension; Hypotension; Isosorbide Dinitrate; Lung Diseases; Male; Middle Aged; Myocardial Infarction; Myocarditis; Regional Blood Flow; Vascular Resistance; Vasodilator Agents; Verapamil; Xanthines | 1971 |
[Drugs used in the treatment of coronary insufficiency (a guide line) to the young physician].
Topics: Coronary Disease; Coumarins; Humans; Monoamine Oxidase Inhibitors; Nitrates; Nitrites; Phenothiazines; Prenylamine; Vasodilator Agents; Verapamil | 1971 |
[Intensain treatment of acute coronary insufficiency].
Topics: Adult; Coronary Disease; Coumarins; Glycolates; Humans; Male; Middle Aged; Propranolol; Vasodilator Agents; Verapamil | 1970 |
The effects of coronary vasodilators on coronary and systemic circulation. Experiments on the hearts of anesthetized dogs.
Topics: Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Aorta; Blood Circulation; Blood Pressure; Coronary Vessels; Coumarins; Dipyridamole; Dogs; Electricity; Glycolates; Heart Rate; Injections; Magnetics; Manometry; Methods; Nitriles; Papaverine; Regional Blood Flow; Vasodilator Agents; Verapamil | 1970 |
[On the effectiveness of orally administered coronary dilator agents].
Topics: Benzoates; Benzopyrans; Butyrates; Coronary Disease; Coumarins; Dipyridamole; Glycolates; Humans; Piperazines; Prenylamine; Tablets; Vasodilator Agents; Verapamil | 1968 |
Inhibition of vitamin D3-induced vascular calcification by carbocromen.
Topics: Animals; Aorta; Calcium; Cholecalciferol; Chromonar; Coumarins; Magnesium; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocardium; Rats; Verapamil | 1983 |
Effects of osthole on isolated guinea pig heart atria.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Coumarins; Depression, Chemical; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Plants, Medicinal; Verapamil | 1995 |
Microscale determination of dissociation constants of multivalent pharmaceuticals by capillary electrophoresis.
Topics: Amino Acid Sequence; Buffers; Electrophoresis; Hydrogen-Ion Concentration; Mathematical Computing; Microchemistry; Molecular Sequence Data; Pharmaceutical Preparations; Pharmacokinetics; Reproducibility of Results; Temperature; Verapamil; Warfarin | 1994 |
[Effects of osthole on the isolated guinea-pig ileum and taeniae coli].
Topics: Acetylcholine; Animals; Calcium; Colon; Coumarins; Female; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Verapamil | 1993 |
Study of interaction between drug enantiomers and serum albumin by capillary electrophoresis.
Topics: Binding, Competitive; Bupivacaine; Electrophoresis, Capillary; Ibuprofen; Isomerism; Protein Binding; Serum Albumin; Verapamil; Warfarin | 1999 |
Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes.
Topics: Animals; Antidepressive Agents; Antimalarials; Antitussive Agents; Calcium Channel Blockers; Cell Survival; Chlorzoxazone; Coloring Agents; Coumarins; Cryopreservation; Cytochrome P-450 Enzyme System; Dextromethorphan; Imipramine; In Vitro Techniques; Liver; Male; Microsomes, Liver; Muscle Relaxants, Central; Oxazines; Pharmaceutical Preparations; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Testosterone; Verapamil; Xanthenes | 2003 |
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Cycle; Coumarins; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Leukemia P388; Membrane Potentials; Mice; Mitochondria; Rhodamine 123; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Verapamil | 2005 |
What do medical records tell us about potentially harmful co-prescribing?
Topics: Adult; Ambulatory Care; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diltiazem; Drug Interactions; Drug Utilization Review; Health Maintenance Organizations; Humans; Lovastatin; Medical Audit; Medication Errors; Office Visits; Polypharmacy; United States; Verapamil; Warfarin | 2007 |
Cluster-like headaches associated with internal carotid artery dissection responsive to verapamil.
Topics: Anticoagulants; Blepharoptosis; Carotid Artery, Internal, Dissection; Cluster Headache; Diagnosis, Differential; Edema; Essential Tremor; Humans; Magnetic Resonance Angiography; Male; Middle Aged; Vasodilator Agents; Verapamil; Vertigo; Warfarin | 2008 |
Studies of verapamil binding to human serum albumin by high-performance affinity chromatography.
Topics: Binding Sites; Binding, Competitive; Chromatography, Affinity; Drug Interactions; Humans; Protein Binding; Serum Albumin; Stereoisomerism; Tamoxifen; Tryptophan; Verapamil; Warfarin | 2008 |
In situ artificial membrane permeation assay under hydrodynamic control: permeability-pH profiles of warfarin and verapamil.
Topics: Anticoagulants; Calcium Channel Blockers; Humans; Hydrogen-Ion Concentration; Membranes, Artificial; Microfluidic Analytical Techniques; Microfluidics; Models, Biological; Permeability; Time Factors; Verapamil; Warfarin | 2010 |
Thiomers: Inhibition of cytochrome P450 activity.
Topics: Aryl Hydrocarbon Hydroxylases; Chitosan; Coumarins; Cysteine; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Carriers; Drug Compounding; Drug Delivery Systems; Enzyme Assays; Enzyme Inhibitors; Excipients; Indicators and Reagents; Polymers; Sulfhydryl Compounds; Verapamil | 2011 |
A kinetic method for the determination of plasma protein binding of compounds unstable in plasma: Specific application to enalapril.
Topics: Adsorption; Animals; Blood Proteins; Centrifugation; Charcoal; Clinical Laboratory Techniques; Dextrans; Dialysis; Dogs; Drug Stability; Enalapril; Guinea Pigs; Humans; In Vitro Techniques; Piperazines; Protein Binding; Purines; Rats; Reproducibility of Results; Sildenafil Citrate; Sulfones; Time Factors; Verapamil; Warfarin | 2011 |
Farnesiferol A from Ferula persica and galbanic acid from Ferula szowitsiana inhibit P-glycoprotein-mediated rhodamine efflux in breast cancer cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Line, Tumor; Coumarins; Drug Resistance, Neoplasm; Female; Ferula; Humans; Plant Extracts; Plant Roots; Rhodamine 123; Sesquiterpenes; Verapamil | 2011 |
Inhibitory effects of furanocoumarin derivatives in Kampo extract medicines on P-glycoprotein at the blood-brain barrier.
Topics: Animals; Apiaceae; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cattle; Citrus paradisi; Coumarins; Endothelial Cells; Enzyme Inhibitors; Fluoresceins; Furans; Furocoumarins; Herb-Drug Interactions; Humans; Intestinal Absorption; Male; Medicine, Kampo; Permeability; Plant Extracts; Rats; Rats, Wistar; Rutaceae; Verapamil | 2011 |
Discovery and explanation of drug-drug interactions via text mining.
Topics: Algorithms; Aryl Hydrocarbon Hydroxylases; Computational Biology; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Data Mining; Drug Interactions; Humans; Knowledge Bases; MEDLINE; Pharmacogenetics; Verapamil; Warfarin | 2012 |
Verapamil does not modify catalytic activity of CYP450 in rainbow trout after long-term exposure.
Topics: Animals; Biomarkers; Calcium Channel Blockers; Coumarins; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Liver; Microsomes, Liver; Nitrophenols; Oncorhynchus mykiss; Oxazines; Verapamil; Water Pollutants, Chemical | 2012 |
[Study on transport mechanism of baicalin in Scutellariae radix extracts and effect of Angelica dahurica extracts on transport of baicalin by Caco-2 cell monolayer model].
Topics: Angelica; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Coumarins; Drug Interactions; Drugs, Chinese Herbal; Flavonoids; Humans; Intestinal Absorption; Oils, Volatile; Plant Extracts; Plant Roots; Probenecid; Scutellaria baicalensis; Verapamil | 2013 |
Predicted contributions of cytochrome P450s to drug metabolism in human liver microsomes using relative activity factor were dependent on probes.
Topics: Atorvastatin; Cytochrome P-450 Enzyme System; Diclofenac; Humans; Kinetics; Microsomes, Liver; Midazolam; Protein Isoforms; Testosterone; Tolbutamide; Verapamil; Warfarin | 2019 |