Compounds > verapamil

verapamil and troleandomycin

verapamil has been researched along with troleandomycin in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (15.38)	18.2507
2000's	6 (46.15)	29.6817
2010's	5 (38.46)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ	1
Dansette, PM; Fontana, E; Poli, SM	1
Pratim Roy, P; Roy, K	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Bader, A; Christians, U; Gonschior, AK; Hackbarth, I; Lampen, A; Sewing, KF; von Engelhardt, W	1
Aguilar, AJ; Grace, JM; Skanchy, DJ	1
Kohno, Y; Suzuki, A; Yamamoto, T	1
Hall, K; Meredith, S; Murray, KT; Narasimhulu, SS; Ray, WA; Stein, CM	1
Al-Shurbaji, A; Annas, A; Artursson, P; Lazorova, L; Svensson, JO; Yasar, U	1
Chen, Y; Fretland, AJ; Liu, L; Monshouwer, M	1
Albaugh, DR; Fisher, MB; Fullenwider, CL; Hutzler, JM	1
Reinen, J; Smit, M; Wenker, M	1

Reviews

1 review(s) available for verapamil and troleandomycin

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005

Other Studies

12 other study(ies) available for verapamil and troleandomycin

Article	Year
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors. Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2 Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors	2001
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques. European journal of medicinal chemistry, 2009, Volume: 44, Issue:7 Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber. British journal of pharmacology, 1996, Volume: 117, Issue:8 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Gastric Mucosa; Immunosuppressive Agents; Ketoconazole; Oxidoreductases, N-Demethylating; Swine; Tacrolimus; Troleandomycin; Vasodilator Agents; Verapamil	1996
Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:7 Topics: Adult; Aged; Antifungal Agents; Antimalarials; Artemisinins; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Interactions; Drugs, Chinese Herbal; Enzyme Inhibitors; Female; Glycyrrhiza; Humans; Inactivation, Metabolic; Inhibitory Concentration 50; Isoenzymes; Ketoconazole; Liver; Male; Miconazole; Microsomes, Liver; Middle Aged; Oxidoreductases, N-Demethylating; Paeonia; Quinidine; Recombinant Proteins; Sesquiterpenes; Sulfaphenazole; Troleandomycin; Vasodilator Agents; Verapamil	1999
High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method. Xenobiotica; the fate of foreign compounds in biological systems, 2004, Volume: 34, Issue:1 Topics: Amiodarone; Animals; Baculoviridae; Binding, Competitive; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diltiazem; Enzyme Inhibitors; Fluorescence; Humans; Inhibitory Concentration 50; Ketoconazole; Miconazole; Midazolam; Propafenone; Quinolines; Recombinant Proteins; Troleandomycin; Verapamil	2004
Oral erythromycin and the risk of sudden death from cardiac causes. The New England journal of medicine, 2004, Sep-09, Volume: 351, Issue:11 Topics: Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Calcium Channel Blockers; Confounding Factors, Epidemiologic; Cytochrome P-450 CYP3A; Death, Sudden, Cardiac; Diltiazem; Drug Interactions; Erythromycin; Female; Humans; Male; Middle Aged; Multivariate Analysis; Nitroimidazoles; Oxidoreductases, N-Demethylating; Risk; Troleandomycin; Verapamil	2004
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:8 Topics: ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Caco-2 Cells; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Isonipecotic Acids; Ketoconazole; Kinetics; Meperidine; Microsomes, Liver; Mutagenesis, Site-Directed; Phenols; Substrate Specificity; Sulfaphenazole; Troleandomycin; Verapamil	2005
Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:11 Topics: Cryopreservation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Hepatocytes; Humans; Microsomes, Liver; Pharmacokinetics; Risk Assessment; Time Factors; Troleandomycin; Verapamil	2011
Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:7 Topics: Cells, Cultured; Clarithromycin; Cryopreservation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Hepatocytes; Humans; Kinetics; Microsomes, Liver; Troleandomycin; Verapamil	2012
Evaluation of Strategies for the Assessment of Drug-Drug Interactions Involving Cytochrome P450 Enzymes. European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:6 Topics: Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Dihydralazine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Microsomes, Liver; Mifepristone; Paroxetine; Theophylline; Troleandomycin; Verapamil	2018