verapamil and ticlopidine

verapamil has been researched along with ticlopidine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.79)18.7374
1990's0 (0.00)18.2507
2000's3 (15.79)29.6817
2010's12 (63.16)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Fujita, M; Iso, T; Iwao, J; Kato, E; Kawashima, Y; Oya, M; Tabashi, K; Yamamoto, K1
Dansette, PM; Fontana, E; Poli, SM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Budriesi, R; Carosati, E; Chiarini, A; Chiu, FC; Cosimelli, B; Frosini, M; Fusi, F; Ioan, P; Katneni, K; Matucci, R; Micucci, M; Saponara, S; Severi, E; Spinelli, D1
Chen, SH; Duan, YC; Guan, YY; He, ZH; Jin, LF; Liu, YJ; Ren, HM; Song, Y; Xu, YT; Yuan, H; Zhang, SJ1
Andriani, A; Chiappetta, MG; Fabiani, M1
Dewanjee, MK; Fuster, V; Kaye, MP; Murphy, KP; Pumphrey, CW; Vlietstra, RE1
Armstrong, G; Dahl, ML; El-Jack, S; Farrell, H; Gladding, P; Gunes, A; Kay, P; Ormiston, J; Ruygrok, P; Scott, D; Stewart, J; Webster, M; Zeng, I1
Baron, JA; Bøtker, HE; Jensen, LO; Johansen, MB; Kaltoft, A; Maeng, M; Robertson, DJ; Schmidt, M; Sørensen, HT; Tilsted, HH1
Degim, T; Ilbasmis-Tamer, S; Incecayir, T; Tirnaksiz, F1

Reviews

3 review(s) available for verapamil and ticlopidine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Platelet aggregation and antiaggregant drugs].
    Recenti progressi in medicina, 1982, Volume: 73, Issue:5

    Topics: Dipyridamole; Humans; Papaverine; Platelet Aggregation; Prostaglandins; Theophylline; Thiophenes; Thromboxane A2; Ticlopidine; Verapamil

1982

Trials

1 trial(s) available for verapamil and ticlopidine

ArticleYear
The antiplatelet effect of higher loading and maintenance dose regimens of clopidogrel: the PRINC (Plavix Response in Coronary Intervention) trial.
    JACC. Cardiovascular interventions, 2008, Volume: 1, Issue:6

    Topics: Administration, Oral; Aged; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Clopidogrel; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Female; Humans; Injections, Intravenous; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Stents; Thrombosis; Ticlopidine; Time Factors; Verapamil

2008

Other Studies

15 other study(ies) available for verapamil and ticlopidine

ArticleYear
Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Pulmonary Embolism; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thiazoles

1988
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism.
    Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Humans; Male; Microsomes, Liver; Myocytes, Cardiac; Oxadiazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazines; Vasodilator Agents

2016
Design, synthesis, and biological evaluation of novel dual inhibitors targeting lysine specific demethylase 1 (LSD1) and histone deacetylases (HDAC) for treatment of gastric cancer.
    European journal of medicinal chemistry, 2021, Aug-05, Volume: 220

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Deacetylases; Histone Demethylases; Humans; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Rats; Stomach Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2021
A new in vivo model of arterial thrombosis: the effect of administration of ticlopidine and verapamil in dogs.
    Thrombosis research, 1982, Dec-01, Volume: 28, Issue:5

    Topics: Administration, Oral; Animals; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Femoral Artery; Fibrinolytic Agents; Injections, Intravenous; Platelet Aggregation; Thiophenes; Thrombosis; Ticlopidine; Verapamil

1982
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Child; Child, Preschool; Clopidogrel; Cohort Studies; Denmark; Drug Interactions; Felodipine; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Stents; Ticlopidine; Verapamil; Young Adult

2012
I am a 37-year-old woman and was diagnosed with coronary artery spasms two years ago. I am taking Plavix, verapamil and Imdur for my condition. What other things can I do to help my heart?
    Heart advisor, 2011, Volume: 14, Issue:7

    Topics: Adult; Clopidogrel; Coronary Vasospasm; Coronary Vessels; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Isosorbide Dinitrate; Ticlopidine; Vasodilator Agents; Verapamil

2011
Assessment of the potential drug-drug interaction between carvedilol and clopidogrel mediated through intestinal P-glycoprotein.
    Die Pharmazie, 2016, 08-01, Volume: 71, Issue:8

    Topics: Adrenergic beta-Antagonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbazoles; Carvedilol; Clopidogrel; Drug Interactions; Intestinal Absorption; Intestine, Small; Male; Metoprolol; Perfusion; Permeability; Platelet Aggregation Inhibitors; Propanolamines; Rats; Rats, Wistar; Ticlopidine; Verapamil

2016