verapamil and scopolamine hydrobromide

verapamil has been researched along with scopolamine hydrobromide in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's3 (13.04)18.2507
2000's7 (30.43)29.6817
2010's9 (39.13)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bard, B; Carrupt, PA; Martel, S1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cai, P; Kong, LY; Liu, QH; Wang, XB; Wang, ZM; Wu, JJ; Xu, DQ; Yang, XL1
Janowsky, DS; Overstreet, DH; Rezvani, AH1
Liu, ZM; Wang, YT1
McCann, DJ; Rabin, RA; Winter, JC1
Furukawa, K; Nomoto, T; Tonoue, T1
Haraguchi, K; Iga, T; Ito, K; Kotaki, H; Sawada, Y1
Bankstahl, JP; Bankstahl, M; Ding, XQ; Kuntner, C; Langer, O; Löscher, W; Meier, M; Müller, M; Stanek, J; Wanek, T1
Bang, E; Duman, RS; Ghosal, S; Girgenti, MJ; Hare, BD; Lepack, AE; Yue, W1
Gu, X; Hu, J; Li, M; Lv, D; Shen, X; Sun, X; Wang, C; Wang, J; Yu, H1
Boopathy, R; Kumar, CR; Ponne, S1

Reviews

1 review(s) available for verapamil and scopolamine hydrobromide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for verapamil and scopolamine hydrobromide

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Nov-10, Volume: 123

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Copper; Donepezil; Drug Design; Humans; Indans; Kinetics; Liver; Mice; Models, Molecular; Peptide Fragments; Piperidines; Protein Aggregates; Protein Conformation

2016
Drug-induced reductions in ethanol intake in alcohol preferring and Fawn-Hooded rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Alcohol Drinking; Alcoholism; Animals; Buspirone; Drinking Behavior; Ethanol; Feeding Behavior; Fluoxetine; Male; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Rats, Wistar; Scopolamine; Self Administration; Serotonin Receptor Agonists; Species Specificity; Verapamil

1991
Morphometric study of neuromuscular junction in rabbits subjected to shock by superior mesenteric artery occlusion.
    Critical care medicine, 1990, Volume: 18, Issue:2

    Topics: Acetylcholinesterase; Adenosine Triphosphate; Animals; Liver; Mesenteric Arteries; Mesenteric Vascular Occlusion; Neuromuscular Junction; Rabbits; Scopolamine; Shock; Verapamil

1990
Use of the radial maze in studies of phencyclidine and other drugs of abuse.
    Physiology & behavior, 1987, Volume: 40, Issue:6

    Topics: Animals; Brain; Learning; Lysergic Acid Diethylamide; Memory; Organ Specificity; Phenazocine; Phencyclidine; Scopolamine; Substance-Related Disorders; Verapamil

1987
Transition from neurogenic to myogenic receptivity for thyrotropin-releasing hormone (TRH) in the duodenum of the neonatal rat.
    Endocrinology, 1981, Volume: 108, Issue:2

    Topics: Acetylcholine; Aging; Animal Population Groups; Animals; Animals, Newborn; Animals, Suckling; Duodenum; Female; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Scopolamine; Tetrodotoxin; Thyrotropin-Releasing Hormone; Verapamil

1981
Catalepsy induced by calcium channel blockers in mice.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:2

    Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Catalepsy; Dihydropyridines; Diltiazem; Disease Models, Animal; Flunarizine; Male; Mice; Muscarinic Antagonists; Nitrobenzenes; Piperazines; Predictive Value of Tests; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Time Factors; Verapamil

1998
A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jun-15, Volume: 31, Issue:24

    Topics: Analysis of Variance; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Calcium Channel Blockers; Carbon Isotopes; Computer Simulation; Disease Models, Animal; Female; Gene Expression Regulation; Heterocyclic Compounds; Magnetic Resonance Imaging; Models, Chemical; Organometallic Compounds; Pilocarpine; Positron-Emission Tomography; Quinolines; Rats; Rats, Sprague-Dawley; Scopolamine; Seizures; Time Factors; Verapamil

2011
Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of Scopolamine.
    Biological psychiatry, 2018, Jan-01, Volume: 83, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Calcium Channels, L-Type; Cells, Cultured; Depressive Disorder; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid; Male; Mice, Transgenic; Motor Activity; Neurons; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptor, trkB; Scopolamine; Synaptosomes; Time Factors; Verapamil

2018
The Requirement of L-Type Voltage-Dependent Calcium Channel (L-VDCC) in the Rapid-Acting Antidepressant-Like Effects of Scopolamine in Mice.
    The international journal of neuropsychopharmacology, 2018, 02-01, Volume: 21, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Calcium Channels, L-Type; Cognitive Dysfunction; Depression; Disease Models, Animal; Hippocampus; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Neuropeptides; Prefrontal Cortex; Scopolamine; Verapamil

2018
Verapamil attenuates scopolamine induced cognitive deficits by averting oxidative stress and mitochondrial injury - A potential therapeutic agent for Alzheimer's Disease.
    Metabolic brain disease, 2020, Volume: 35, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Brain; Cell Line, Tumor; Cell Survival; Cognition Disorders; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neuroprotective Agents; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Scopolamine; Verapamil

2020