verapamil and pyrilamine

verapamil has been researched along with pyrilamine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.00)18.7374
1990's8 (28.57)18.2507
2000's8 (28.57)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Achterrath, U; Duflos, M; Emig, P; Fouchard, F; Günther, E; Kutscher, B; Le Baut, G; Menciu, C; Nickel, B; Schmidt, J; Szelenyi, I1
Nezu, J; Oku, A; Sai, Y; Sakamoto, K; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahman, M; Holmén, AG; Wan, H1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Papadimituiou, JM; Sforcina, D1
Bertaccini, G; Coruzzi, G; Vitali, T1
Brandes, LJ; LaBella, FS1
Yang, P1
Franz, DR; Robinson, CP1
Blanco, I; Rodriguez, J; Rodriguez, R; Sabriá, J; Toledo, A1
Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM1
Kanaide, H; Kobayashi, S; Kuga, T; Matsumoto, T; Nakamura, M; Nishimura, J1
McCormick, JP; Russell, JA1
Asano, M; Hidaka, H1
Buck, MG; Goswami, S; Maayani, S; Marom, Z; Rienzi, N; Schachter, EN; Zuskin, E1
Atwell, R; Brown, L; Campbell, F; Fenning, A; Hoey, A1
Kato, Y; Kubo, Y; Sugiura, T; Tsuji, A1
Akanuma, S; Hosoya, K; Kubo, Y; Kusagawa, Y; Tachikawa, M1
Akanuma, S; Hosoya, K; Kubo, Y; Tega, Y; Yuzurihara, C1
Kubo, Y1
Akanuma, SI; Ehrhardt, C; Hosoya, KI; Kubo, Y; Tega, Y; Yuzurihara, C1

Reviews

1 review(s) available for verapamil and pyrilamine

ArticleYear
[Carrier-mediated Transport of Cationic Drugs across the Blood-Tissue Barrier].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:10

    Topics: Angiogenesis Inhibitors; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Cation Transport Proteins; Clonidine; Drug Carriers; Humans; Nervous System Diseases; Neuroprotective Agents; Propranolol; Pyrilamine; Verapamil

2015

Other Studies

27 other study(ies) available for verapamil and pyrilamine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbachol; Eosinophilia; Guinea Pigs; Histamine Release; Hypersensitivity; In Vitro Techniques; Indoleacetic Acids; Interleukin-4; Interleukin-5; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; Peritoneal Cavity; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rhinitis, Allergic, Perennial; Structure-Activity Relationship; Trachea

1999
Novel membrane transporter OCTN1 mediates multispecific, bidirectional, and pH-dependent transport of organic cations.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:2

    Topics: Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Gene Expression; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Oocytes; Organic Cation Transport Proteins; Quinidine; RNA, Messenger; Symporters; Tetraethylammonium Compounds; Xenopus laevis

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
    Molecular pharmacology, 2001, Volume: 59, Issue:2

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The effects of drugs on monocytic fusion in vivo.
    Experimental cell research, 1975, Mar-15, Volume: 91, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Fusion; Cell Membrane; Cortisone; Cyclic AMP; Diphenhydramine; Edetic Acid; Glucagon; Insulin; Isoproterenol; Lidocaine; Lysosomes; Male; Mice; Mice, Inbred C57BL; Monocytes; Ouabain; Pyrilamine; Tetracaine; Trifluoperazine; Verapamil

1975
Effect of histamine and related compounds on the papillary muscle of the guinea pig.
    Pharmacological research communications, 1978, Volume: 10, Issue:8

    Topics: Animals; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Papillary Muscles; Pyrilamine; Structure-Activity Relationship; Verapamil

1978
Histamine and calcium are independently regulated intracellular mediators of lymphocyte mitogenesis.
    Biochemical and biophysical research communications, 1992, Jan-31, Volume: 182, Issue:2

    Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebral Cortex; Cimetidine; Concanavalin A; DNA Replication; Histamine; Histamine Antagonists; Kinetics; Lymphocytes; Mice; Mice, Inbred BALB C; Phenyl Ethers; Pyrilamine; Rats; Receptors, Histamine H1; Receptors, Nicotinic; Spleen; Verapamil

1992
[The effect of histamine on the levels of cyclic nucleotides in the nasal mucosa tissue of rats].
    Zhonghua er bi yan hou ke za zhi, 1992, Volume: 27, Issue:3

    Topics: Animals; Cyclic AMP; Cyclic GMP; Histamine; Male; Nasal Mucosa; Pyrilamine; Rats; Rats, Wistar; Verapamil

1992
Effects of palytoxin on guinea pig tracheal strips.
    Pharmaceutical research, 1991, Volume: 8, Issue:7

    Topics: Acrylamides; Airway Resistance; Animals; Atropine; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Pyrilamine; Sodium; Solutions; Trachea; Verapamil

1991
A comparative study of histamine and K+ effects on (Ca(2+)-Mg2+)-ATPase activity in synaptosomes.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium Chloride; Calcium-Transporting ATPases; Cell Membrane; Choline; Diltiazem; Dose-Response Relationship, Drug; Histamine; Potassium; Pyrilamine; Ranitidine; Rats; Sodium; Synapses; Synaptosomes; Verapamil

1991
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
    Biochemical and biophysical research communications, 1989, Feb-15, Volume: 158, Issue:3

    Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil

1989
Histamine-induced calcium transients in vascular smooth muscle cells: effects of verapamil and diltiazem.
    The American journal of physiology, 1989, Volume: 257, Issue:2 Pt 2

    Topics: Aminoquinolines; Animals; Aorta; Calcium; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient; Cimetidine; Cytosol; Diltiazem; Fluorescent Dyes; Histamine; Kinetics; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyrilamine; Rats; Rats, Inbred Strains; Sarcolemma; Swine; Verapamil

1989
Lacinilene C methyl ether (LCME) constricts tracheal smooth muscle.
    Environmental research, 1988, Volume: 45, Issue:1

    Topics: Animals; Atropine; Dogs; Drug Interactions; In Vitro Techniques; Isoproterenol; Methysergide; Muscle Contraction; Muscle, Smooth; Naphthols; Pyrilamine; Trachea; Verapamil

1988
Potentiation in various agonists-induced contractions of rabbit mesenteric artery by sulfhydryl reagents.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:1

    Topics: Animals; Calcium; Drug Synergism; Female; In Vitro Techniques; Male; Mercaptoethanol; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Potassium Chloride; Pyrilamine; Rabbits; Sulfhydryl Reagents; Verapamil

1983
Pharmacologic characterization of wool dust extract in isolated guinea pig trachea.
    Environmental research, 1995, Volume: 69, Issue:2

    Topics: Air Pollutants, Occupational; Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Male; Occupational Exposure; Pyrilamine; Trachea; Verapamil; Wool

1995
Cardiovascular effects of the toxin(s) of the Australian paralysis tick, Ixodes holocyclus, in the rat.
    Toxicon : official journal of the International Society on Toxinology, 2004, Jun-01, Volume: 43, Issue:7

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antitoxins; Cimetidine; Dose-Response Relationship, Drug; Electrophysiology; Histological Techniques; Ixodes; Male; Metoprolol; Microelectrodes; Microscopy, Electron; Myocardial Contraction; Myocardium; Pinacidil; Pyrilamine; Rats; Rats, Wistar; Spider Venoms; Tetrodotoxin; Verapamil

2004
Mutation in an adaptor protein PDZK1 affects transport activity of organic cation transporter OCTNs and oligopeptide transporter PEPT2.
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:5

    Topics: Adaptor Protein Complex gamma Subunits; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cell Line; Cell Membrane; Dipeptides; Humans; Membrane Proteins; Mutation; Organic Cation Transport Proteins; Organic Cation Transporter 1; Protein Binding; Pyrilamine; Solute Carrier Family 22 Member 5; Symporters; Tetraethylammonium; Transfection; Tritium; Two-Hybrid System Techniques; Verapamil

2006
Involvement of a novel organic cation transporter in verapamil transport across the inner blood-retinal barrier.
    Pharmaceutical research, 2013, Volume: 30, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Blood-Retinal Barrier; Cations; Cell Line; Male; Organic Cation Transport Proteins; Pyrilamine; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

2013
Carrier-Mediated Transport of Nicotine Across the Inner Blood-Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H(+) Gradient.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:9

    Topics: Animals; Biological Transport; Blood-Retinal Barrier; Carrier Proteins; Cations; Cell Line; Endothelial Cells; Hydrogen; Male; Nicotine; Organic Cation Transport Proteins; Pyrilamine; Rats; Rats, Wistar; Retina; Retinal Vessels; Verapamil

2015
Functional expression of nicotine influx transporter in A549 human alveolar epithelial cells.
    Drug metabolism and pharmacokinetics, 2016, Volume: 31, Issue:1

    Topics: Adrenergic beta-Agonists; Biological Transport; Cell Line, Tumor; Epithelial Cells; Humans; Nicotine; Organic Cation Transport Proteins; Pulmonary Alveoli; Pyrilamine; Verapamil

2016