verapamil has been researched along with pimozide in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 18 (54.55) | 29.6817 |
| 2010's | 10 (30.30) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Desir, GV; Lang, R; Lee, G; Liu, W; Orias, M; Rafi, H; Segal, AS; Tian, S | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Aszalos, A; Ibrahim, S; Knapton, A; Licht, T; Peggins, J | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Chen, XL; Hendrix, J; Kang, J; Korolev, AM; Lysenkova, LN; Miroshnikova, OV; Pearlstein, RA; Preobrazhenskaya, M; Rampe, D; Shchekotikhin, AE; Vaz, RJ | 1 |
| Keserü, GM | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Racker, E; Westcott, D; Wu, LT | 1 |
| Jackson, GL; Liu, TC | 1 |
| Bilezikjian, LM; Vale, WW | 1 |
| Crawford, F; Fang, C; Mullan, M; Suo, Z | 1 |
| Canchola-Martínez, E; Mercado-Sánchez, G; Rodríguez-Medina, MA; Vergara-Onofre, M | 1 |
| Ceric, F; Kerr, B; Kong, M; Morales, P; Pizarro, E; Vigil, P | 1 |
| Bondioli, KR; Bonk, AJ; Macháty, Z; Prather, RS; Ramsoondar, JJ | 1 |
| Connolly, TM; Figueroa, DJ; Lawlor, AM; Liang, HA; Liu, Y; Salata, JJ; Xia, M | 1 |
| Bansal, P; Bhandari, B; Gupta, SK; Talwar, P | 1 |
| Covell, DG | 1 |
1 review(s) available for verapamil and pimozide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for verapamil and pimozide
| Article | Year |
|---|---|
KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels.
Topics: Animals; Base Sequence; Cyclic Nucleotide-Gated Cation Channels; DNA Primers; Female; Humans; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Potentials; Oocytes; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rabbits; Recombinant Proteins; Second Messenger Systems; Shaker Superfamily of Potassium Channels; Xenopus laevis | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Influence of antipsychotic, antiemetic, and Ca(2+) channel blocker drugs on the cellular accumulation of the anticancer drug daunorubicin: P-glycoprotein modulation.
Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Antiemetics; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Calcium Channel Blockers; Daunorubicin; Flow Cytometry; Humans; Mice; Transfection | 2000 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches.
Topics: Amino Acids, Aromatic; Cation Transport Proteins; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Imidazoles; Indoles; Inhibitory Concentration 50; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Structural Homology, Protein; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Use of slow Ca2+ channel blockers to enhance inhibition by taxol of growth of drug-sensitive and -resistant Chinese hamster ovary cells.
Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Calcium Channel Blockers; Cell Division; Cells, Cultured; Colchicine; Cricetinae; Cricetulus; Daunorubicin; Drug Resistance; Female; Nicotinic Acids; Nimodipine; Ovary; Paclitaxel; Pimozide; Verapamil | 1986 |
Synthesis and release of luteinizing hormone in vitro by rat anterior pituitary cells: effects of gallopamil hydrochloride (D600) and pimozide.
Topics: Alanine; Animals; Carbohydrate Metabolism; Gallopamil; Glucosamine; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pimozide; Pituitary Gland, Anterior; Rats; Verapamil | 1985 |
Stimulation of adenosine 3',5'-monophosphate production by growth hormone-releasing factor and its inhibition by somatostatin in anterior pituitary cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pimozide; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Time Factors; Verapamil | 1983 |
Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial toxicity.
Topics: Amyloid beta-Peptides; Antipsychotic Agents; Aorta; Apoptosis; Calcium; Calcium Channel Blockers; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radicals; Humans; Necrosis; Peptide Fragments; Pimozide; Superoxide Dismutase; Superoxides; Time Factors; Verapamil | 1997 |
[Inhibitors of calcium-calmodulin system and hypothalamic sex differentiation in rats. Biochemical parameters].
Topics: Animals; Animals, Newborn; Antipsychotic Agents; Calcium Channel Blockers; Calmodulin; DNA; Dopamine Antagonists; Female; Haloperidol; Hypothalamus; Male; Organ Size; Ovary; Penfluridol; Pimozide; Proteins; Rats; RNA; Sex Differentiation; Testis; Trifluoperazine; Verapamil | 1997 |
Gonadotropin-releasing hormone-stimulated sperm binding to the human zona is mediated by a calcium influx.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Humans; Male; Mibefradil; Nifedipine; Pimozide; Sperm-Ovum Interactions; Spermatozoa; Verapamil; Zona Pellucida | 2000 |
Na(+)/Ca(2+) exchanger in porcine oocytes.
Topics: Amiloride; Animals; Base Sequence; Bepridil; Calcium; Calcium Channel Blockers; Cell Membrane; Cloning, Molecular; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Immunohistochemistry; Molecular Sequence Data; Oocytes; Ouabain; Pimozide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Swine; Verapamil | 2002 |
Functional expression of L- and T-type Ca2+ channels in murine HL-1 cells.
Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Electric Conductivity; Heart Atria; Ion Transport; Mibefradil; Mice; Myocytes, Cardiac; Nimodipine; Patch-Clamp Techniques; Pimozide; Potassium; Verapamil | 2004 |
Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida.
Topics: Acrosome Reaction; Calcium Channel Blockers; Dopamine Agonists; Female; Fluorescent Dyes; Hot Temperature; Humans; Male; Pimozide; Plant Lectins; Rhodamines; Signal Transduction; Solubility; Sperm Capacitation; Verapamil; Zona Pellucida | 2010 |
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil | 2012 |