verapamil and phenytoin

verapamil has been researched along with phenytoin in 128 studies

Research

Studies (128)

Timeframe	Studies, this research(%)	All Research%
pre-1990	71 (55.47)	18.7374
1990's	11 (8.59)	18.2507
2000's	18 (14.06)	29.6817
2010's	26 (20.31)	24.3611
2020's	2 (1.56)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Anger, T; Madge, DJ; Mulla, M; Riddall, D	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Baltes, S; Fedrowitz, M; Gastens, AM; Kaever, V; Löscher, W; Potschka, H	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Gozalbes, R; Pineda-Lucena, A	1
Akamatsu, M	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Brouillette, WJ; Brown, GB; Zha, C	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS	1
Julian, DG	1
Theisen, K	1
Donaldson, RM	1
Brochier, M; Fauchier, JP	1
Dretchen, KL; Raines, A; Standaert, FG	1
Bender, F	2
Merx, W	1
Watson, EL	1
Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA	1
Doenecke, VP	1
Hepp, A; Raff, U	1
Loogen, F	1
Doenecke, P	1
Chalfie, M; Hoadley, D; Pastan, S; Perlman, RL	1
Araú, A; Bonhorst, D; Bordalo, A; De Azevedo, JG; Ferreira, M; Ferreira, R; Inês, L; Lacximy, I; Longo, A; Luis Martins, J; Melo, M; Nunes Diogo, A; Ribeiro, C; Sanches, C; Teixeira, J	1
Steinbach, K	1
Arnsdorf, MF	1
Akaike, N; Kameda, H; Kataoka, M; Takahashi, K; Ueno, S	1
De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR	1
Hopf, R; Kaltenbach, M; Kirsten, R; Nelson, K; Rietbrock, S; Woodcock, BG	1
Besser, GM; Grossman, A; Rees, LH; Tsagarakis, S	1
Bahls, FH; Ozuna, J; Ritchie, DE	1
Kano, M; Kudo, Y; Suzuki, N; Takagi, H; Tanakadate, A; Yoshioka, T	1
Lantos, J; Sárosi, I; Temes, G; Török, B	1
Carpenter, CL; Greenberg, DA; Messing, RO	1
Keefe, DL; Miura, D; Somberg, JC	1
Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM; Tally, PW; Yaksh, TL	1
Dretchen, KL; Henderson, TR; Raines, A	1
Eisenberg, M; Kern, IB; Willis, S	1
Antman, EM; Smith, TW	1
Somberg, J	1
Baciewicz, AM; Bekemeyer, WB; Self, TH	1
Fredholm, BB; Hänström, L; Lerner, U	1
Imanaka, S; Ito, K; Matsuda, S; Matsuoka, T; Okada, Y	1
Andersson, KE; Wettrell, G	1
Huang, SK; Marcus, FI	1
Anderson, RE; Ots, ME; Sundt, TM; Yaksh, TL	1
Balazs, T; Ehrreich, SJ; el-Hage, AN; Johnson, GL	1
Hashimoto, K; Imai, S; Shibuya, T	1
Cucchi, G; Giustiniani, S; Robustelli, F	1
Bursztein, S; Heifetz, M; Weinbroum, A	1
Diedrich, R; Hardewig, A	1
Kaufmann, G	1
Clodi, PH; Hartl, O	1
Chatillon, J	1
Gleichmann, U; Loogen, F; Seipel, L	2
Hauswirth, O; Singh, BN	1
Menner, K; Raugenburg, HW; Weigand, KH	1
Heeg, E; Reuter, N; Steiger, H	1
Strubelt, O; Zetler, G	1
Andresen, T; Hardewig, A; Thormann, J	1
Hensel, G	1
Bleifeld, W; Effert, S; Merx, W	1
Heeg, E; Reuter, N	1
Collignon, P; Kulbertus, H	1
Both, A; Breithardt, G; Gleichmann, U; Loogen, F; Seipel, L	1
Zeh, E	1
Boissier, JR; Giudicelli, JF; Larno, S; Witchitz, S	1
Frey, J; Schüffler, J	1
Schollmeyer, P	1
Büchner, M; Effert, S; Grosse-Brockhoff, F	1
Elkayam, U; Frishman, W; Rotmensch, HH	1
Ali, C; Holt, DW; Volans, GN	1
Jahrmärker, H; Theisen, K	1
Erlichman, J; Fleckman, A; Fleischer, N; Schubart, UK	1
Rosen, MR; Wit, AL	1
Halawa, B	1
Hashimoto, K; Imai, S; Satoh, H; Shibuya, T	2
Dreifus, LS; Morganroth, J	1
De Cosmo, G; Foti, A; Proietti, R; Sabato, AF	1
Bittar, EE; Nwoga, J	1
Gillette, PC	1
Akera, T; Brody, TM; Brown, BS	1
Lazarus, LH; Spracklen, FH	1
Chung, DH; Cooper, CW; Ishizuka, J; Rajaraman, S; Sato, K; Thompson, JC; Townsend, CM; Tsuchiya, T; Uchida, T	1
Beck, WT; Schuetz, EG; Schuetz, JD	1
Desai, P; Silver, JG	1
Fisher, JD; Hallidie-Smith, KA; Krikler, D	1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA	1
Akimoto, Y; Fujii, A; Matsumoto, H; Noji, I	1
Marsh, E; O'Callaghan, P; Smith, P	1
Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM	1
Baum, L; Kwan, P; Zhang, C; Zuo, Z	1
Bedada, SK; Ganji, D; Neerati, P	1
Luna-Munguia, H; Orozco-Suarez, S; Rocha, L	1
Ding, AW; Duan, JA; Lü, GH; Lu, WJ; Ma, HY; You, FQ; Zhou, J	1
Alvariza, S; Fagiolino, P; Orozco Suárez, S; Rocha, L; Rosillo de la Torre, A; Vázquez, M	1
Chen, Y; Ma, A; Wang, C; Yuan, W	1
Ohtsuki, S; Terasaki, T; Uchida, Y	1
Chen, SL; Fan, Q; Ma, H; Zhang, C	1
Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Meirinho, S; Rodrigues, M	1
Ito, S; Iwamoto, K; Kamimura, H; Mizunaga, M; Nakayama, K; Negoro, T; Nishiwaki, M; Nomura, Y; Suemizu, H; Yamazaki, H; Yoneda, N	1

Reviews

18 review(s) available for verapamil and phenytoin

Article	Year
Medicinal chemistry of neuronal voltage-gated sodium channel blockers. Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke	2001
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Cardiac arrhythmias - a short review. Scottish medical journal, 1976, Volume: 21, Issue:3 Topics: Adrenergic beta-Agonists; Arrhythmias, Cardiac; Digitalis Glycosides; Electric Countershock; Electrocardiography; Humans; Lidocaine; Mexiletine; Pacemaker, Artificial; Phenytoin; Procainamide; Quinidine; Verapamil	1976
The treatment of ventricular rhythm disturbances. American heart journal, 1986, Volume: 111, Issue:6 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil	1986
Digitalis toxicity. Annual review of medicine, 1985, Volume: 36 Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Biological Availability; Carotid Sinus; Digitalis Glycosides; Drug Interactions; Electric Countershock; Heart; Heart Conduction System; Humans; Kinetics; Lidocaine; Parasympathetic Nervous System; Phenytoin; Potassium; Procainamide; Quinidine; Sympathetic Nervous System; Verapamil	1985
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Cardiovascular drugs. I: Antidysrhythmic drugs. Therapeutic drug monitoring, 1986, Volume: 8, Issue:1 Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Disopyramide; Drug Interactions; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
[Anti-arrhythmia agents]. Medizinische Klinik, 1974, May-03, Volume: 69, Issue:18 Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Heart; Heart Conduction System; Humans; Lidocaine; Phenytoin; Practolol; Procainamide; Quinidine; Sparteine; Ventricular Fibrillation; Verapamil	1974
Comparative mechanisms of action of antiarrhythmic drugs. American heart journal, 1974, Volume: 87, Issue:3 Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil	1974
[Modern treatment of cardiac arrhythmias]. Munchener medizinische Wochenschrift (1950), 1971, Apr-16, Volume: 113, Issue:16 Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bradycardia; Cell Membrane Permeability; Digitalis Glycosides; Electric Countershock; Heart; Heart Block; Humans; Hypoxia; Magnesium; Metaproterenol; Myocardium; Pacemaker, Artificial; Phenytoin; Phytotherapy; Plants, Medicinal; Potassium; Quinidine; Rauwolfia; Sodium; Sparteine; Tachycardia; Ventricular Fibrillation; Verapamil	1971
[Bundle of His ECG]. Medizinische Klinik, 1974, Nov-22, Volume: 69, Issue:47 Topics: Ajmaline; Bundle of His; Cardiac Catheterization; Digitalis; Electrocardiography; Heart Block; Heart Conduction System; Humans; Phenytoin; Plants, Medicinal; Plants, Toxic; Verapamil	1974
Antiarrhythmic drug therapy during pregnancy. Annals of internal medicine, 1983, Volume: 98, Issue:4 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis Glycosides; Disopyramide; Female; Fetus; Humans; Infant, Newborn; Lidocaine; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Tachycardia; Verapamil	1983
[Medical treatment of extrasystole and tachycardia (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1980, Jan-18, Volume: 122, Issue:3 Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil	1980
Electropharmacology of antiarrhythmic drugs. American heart journal, 1983, Volume: 106, Issue:4 Pt 2 Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil	1983
Antiarrhythmic agents and their use in therapy. Pharmacology & therapeutics, 1980, Volume: 9, Issue:1 Topics: Acebutolol; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Humans; Lidocaine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1980
Drug-induced gingival enlargements. Journal (Canadian Dental Association), 1998, Volume: 64, Issue:4 Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin; Verapamil	1998
The humble electrocardiogram. Practical neurology, 2008, Volume: 8, Issue:1 Topics: Anticonvulsants; Arrhythmias, Cardiac; Brain Diseases; Electrocardiography; Heart; Humans; Nervous System Diseases; Neurology; Phenytoin; Unconsciousness; Vasodilator Agents; Verapamil	2008

Other Studies

110 other study(ies) available for verapamil and phenytoin

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology, 2007, Volume: 52, Issue:2 Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Carbamazepine; Cell Line; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression; Humans; Levetiracetam; Mice; Phenytoin; Piracetam; Transfection	2007
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels	2014
The antitubercular activity of various nitro(triazole/imidazole)-based compounds. Bioorganic & medicinal chemistry, 2017, 11-01, Volume: 25, Issue:21 Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles	2017
[Drug therapy of tachyarrhythmias (author's transl)]. Klinische Wochenschrift, 1978, Feb-15, Volume: 56, Issue:4 Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil	1978
The treatment of supraventricular arrhythmias. British journal of hospital medicine, 1979, Volume: 21, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Digoxin; Disopyramide; Electric Countershock; Humans; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil	1979
["Torsades de pointe" and reentry induced by anti-arrhythmia agents]. Archives des maladies du coeur et des vaisseaux, 1978, Volume: 71, Issue:4 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Flutter; Bretylium Compounds; Cardiac Complexes, Premature; Humans; Phenytoin; Prenylamine; Quinidine; Tachycardia; Ventricular Fibrillation; Verapamil	1978
Effects of phenytoin on the cyclic nucleotide system in the motor nerve terminal. Epilepsia, 1977, Volume: 18, Issue:3 Topics: Animals; Bucladesine; Calcium Chloride; Cats; Electric Stimulation; Evoked Potentials; Hindlimb; Motor Neurons; Muscle Contraction; Neuromuscular Junction; Nucleotides, Cyclic; Phenytoin; Pyridines; Sodium Fluoride; Tetany; Tetraethylammonium Compounds; Theophylline; Verapamil	1977
[Letter: Paroxysmal supraventricular and ventricular tachycardia]. Deutsche medizinische Wochenschrift (1946), 1975, Sep-05, Volume: 100, Issue:36 Topics: Adrenergic beta-Antagonists; Aprindine; Heart Ventricles; Humans; Lidocaine; Phenytoin; Quinidine; Tachycardia, Paroxysmal; Time Factors; Verapamil	1975
[New aspects concerning drug therapy of arrhythmia]. Die Medizinische Welt, 1975, Aug-29, Volume: 6, Issue:35 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Autonomic Nervous System; Bretylium Compounds; Humans; Lidocaine; Membrane Potentials; Parasympatholytics; Parasympathomimetics; Phenytoin; Procainamide; Quinidine; Verapamil	1975
Effects of ionophores A23187 and X537A on vascular smooth muscle activity. European journal of pharmacology, 1978, Nov-15, Volume: 52, Issue:2 Topics: Animals; Anti-Bacterial Agents; Blood Vessels; Calcimycin; Coronary Vessels; Dogs; Drug Interactions; In Vitro Techniques; Lasalocid; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenytoin; Potassium Chloride; Time Factors; Verapamil	1978
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses. Drugs, 1978, Volume: 15, Issue:4 Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1978
[Myocardial excitability under the influence of digitalis glycosides and anti-arrhythmia agent]. Fortschritte der Medizin, 1977, Jan-20, Volume: 95, Issue:3 Topics: Ajmaline; Anti-Arrhythmia Agents; Digitalis Glycosides; Digoxin; Heart Conduction System; Humans; Lidocaine; Myocardial Contraction; Phenytoin; Procainamide; Propranolol; Refractory Period, Electrophysiological; Stimulation, Chemical; Verapamil	1977
[The influence of antiarrhythmic drugs on the exercise-ecg (author's transl)]. Zeitschrift fur Kardiologie, 1977, Volume: 66, Issue:2 Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Exercise Test; Heart Rate; Humans; Methods; Phenytoin; Propranolol; Quinidine; Verapamil	1977
[Sino-atrial conduction time]. Deutsche medizinische Wochenschrift (1946), 1977, Mar-18, Volume: 102, Issue:11 Topics: Ajmaline; Disopyramide; Heart Conduction System; Humans; Phenytoin; Quinidine; Time Factors; Verapamil	1977
[Influence of cardiac agents on the diastolic irritability of the ventricular myocardium. Consequences for pacemaker therapy]. Annales Universitatis Saraviensis. Medizin, 1976, Volume: 23, Issue:2 Topics: Adult; Aged; Ajmaline; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Dogs; Female; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Contraction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Stimulation, Chemical; Verapamil	1976
Calcium uptake into rat pheochromocytoma cells. Journal of neurochemistry, 1976, Volume: 27, Issue:6 Topics: Animals; Calcium; Catecholamines; Drug Interactions; In Vitro Techniques; Phenytoin; Pheochromocytoma; Potassium; Rats; Time Factors; Verapamil	1976
Mechanism of action of antidysrhythmic drugs on ventricular conduction as studied with intramural electrodes. Advances in cardiology, 1975, Volume: 14 Topics: Ajmaline; Animals; Disopyramide; Dogs; Electrocardiography; Heart Conduction System; Hydroxyzine; Lidocaine; Oxprenolol; Phenytoin; Propranolol; Purkinje Fibers; Quinidine; Verapamil	1975
[Treatment of arrhythmia in general practice]. Wiener medizinische Wochenschrift (1946), 1975, Nov-14, Volume: 125, Issue:46 Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Humans; Isoproterenol; Lidocaine; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia; Verapamil	1975
Electrophysiologic properties of antidysrhythmic drugs as a rational basis for therapy. The Medical clinics of North America, 1976, Volume: 60, Issue:2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Hemodynamics; Humans; Lidocaine; Osmolar Concentration; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1976
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons. Neuroscience letters, 1992, Dec-14, Volume: 148, Issue:1-2 Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil	1992
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice. General pharmacology, 1992, Volume: 23, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil	1992
A reduction in verapamil concentrations with phenytoin. The New England journal of medicine, 1991, Oct-17, Volume: 325, Issue:16 Topics: Adult; Cardiomyopathy, Hypertrophic; Drug Interactions; Epilepsy; Female; Humans; Phenytoin; Verapamil	1991
Involvement of calmodulin in depolarization-induced release of corticotrophin-releasing hormone-41 from the rat hypothalamus in vitro. Journal of molecular endocrinology, 1991, Volume: 7, Issue:1 Topics: Animals; Calcimycin; Calcium; Calmodulin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hypothalamus; In Vitro Techniques; Membrane Potentials; Phenytoin; Potassium Chloride; Radioimmunoassay; Rats; Trifluoperazine; Verapamil; Veratridine	1991
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin. Neurology, 1991, Volume: 41, Issue:5 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Retrospective Studies; Seizures; Verapamil	1991
Participation of transient-type Ca2+ channels in the sustained increase of Ca2+ level in GH3 cells. Journal of cellular physiology, 1990, Volume: 144, Issue:1 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Nickel; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Phenytoin; Pituitary Gland; Rats; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured; Verapamil	1990
Influence of protective drugs on the EEG during short-term transient ischaemia. Acta physiologica Hungarica, 1990, Volume: 75, Issue:3 Topics: Animals; Dogs; Electroencephalography; Ischemic Attack, Transient; Lidocaine; Phenytoin; Piracetam; Pyridoxine; Thiopental; Verapamil	1990
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil	1985
Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker. Brain research, 1986, Oct-01, Volume: 384, Issue:1 Topics: Animals; Catheterization; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intra-Arterial; Ion Channels; Nimodipine; Phenytoin; Rabbits; Seizures; Verapamil	1986
Effects of calcium channel blocking agents on neostigmine-induced fasciculations. European journal of pharmacology, 1989, Nov-28, Volume: 173, Issue:1 Topics: Animals; Calcium Channel Blockers; Electric Stimulation; Facial Muscles; Fasciculation; Male; Neostigmine; Nerve Endings; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Verapamil	1989
Management of oesophageal stenosis in epidermolysis bullosa dystrophica. Archives of disease in childhood, 1989, Volume: 64, Issue:4 Topics: Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Deglutition Disorders; Dilatation; Epidermolysis Bullosa; Esophageal Stenosis; Female; Humans; Male; Phenytoin; Verapamil	1989
Update on rifampin drug interactions. Archives of internal medicine, 1987, Volume: 147, Issue:3 Topics: Adrenergic beta-Antagonists; Cyclosporins; Digoxin; Drug Interactions; Humans; Ketoconazole; Phenytoin; Rifampin; Theophylline; Verapamil	1987
Diphenylhydantoin inhibits parathyroid hormone and prostaglandin E2-stimulated bone resorption in mouse calvaria without affecting cyclic AMP formation. Journal of oral pathology, 1985, Volume: 14, Issue:8 Topics: Animals; Bone Resorption; Calcium; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Glycoside Hydrolases; Mice; Parathyroid Hormone; Phenytoin; Prostaglandins E; Skull; Time Factors; Tritium; Verapamil	1985
Medical treatment for inoperable insulinoma: clinical usefulness of diphenylhydantoin and diltiazem. Japanese journal of clinical oncology, 1986, Volume: 16, Issue:1 Topics: Adenoma, Islet Cell; Aged; Benzazepines; Blood Glucose; C-Peptide; Celiac Artery; Diltiazem; Female; Humans; Insulin; Insulinoma; Pancreatic Neoplasms; Phenytoin; Propranolol; Radiography; Verapamil	1986
Effect of dihydropyridines and diphenylalkylamines on pentylenetetrazol-induced seizures and cerebral blood flow in cats. Journal of neurosurgery, 1987, Volume: 67, Issue:3 Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cats; Cerebrovascular Circulation; Clonazepam; Electroencephalography; Female; Male; Nimodipine; Pentylenetetrazole; Phenytoin; Seizures; Verapamil	1987
Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death. Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Body Weight; Bretylium Tosylate; Death, Sudden; Disease Models, Animal; Electrocardiography; Isoproterenol; Male; Niacin; Phenytoin; Procainamide; Propranolol; Quaternary Ammonium Compounds; Quinidine; Rats; Ventricular Fibrillation; Verapamil	1986
Cardiovascular and respiratory effects of antiarrhythmic drugs on conscious beagles. The Tohoku journal of experimental medicine, 1985, Volume: 145, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Disopyramide; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Lidocaine; Male; Phenytoin; Procainamide; Respiration; Verapamil	1985
[Hypertrophic gingivitis caused by verapamil]. Giornale italiano di cardiologia, 1985, Volume: 15, Issue:5 Topics: Angina Pectoris; Gingivitis; Humans; Hyperplasia; Male; Middle Aged; Phenytoin; Verapamil	1985
[Poisoning by tricyclic antidepressants and antidotes]. Harefuah, 1985, Volume: 109, Issue:5-6 Topics: Adolescent; Amitriptyline; Female; Humans; Phenytoin; Physostigmine; Seizures; Suicide, Attempted; Tachycardia; Verapamil	1985
[What is assured in the treatment of heart arrhythmia?]. Der Internist, 1972, Volume: 13, Issue:12 Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Cardiac Complexes, Premature; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil	1972
[Therapy of arrhythmias]. Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1973, Volume: 54, Issue:8-9 Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Premature; Digitalis Glycosides; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Tachycardia; Ventricular Fibrillation; Verapamil	1973
[Modern therapy of cardiac arrhythmias]. Schweizerische medizinische Wochenschrift, 1973, Feb-24, Volume: 103, Issue:8 Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil	1973
[The treatment of cardiac arrhythmias: complexity and schematization]. Revue medicale de la Suisse romande, 1973, Volume: 93, Issue:1 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Benzofurans; Digitalis Glycosides; Electric Countershock; Lidocaine; Phenytoin; Potassium; Procainamide; Quinidine; Tachycardia; Verapamil	1973
[Effect of anti-arrhythmic drugs on intracardiac conduction (His-bundle electrogram) and sinus-node automatism in man]. Deutsche medizinische Wochenschrift (1946), 1973, Volume: 98, Issue:32 Topics: Acetanilides; Adrenergic beta-Antagonists; Ajmaline; Amino Alcohols; Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Block; Heart Conduction System; Humans; Middle Aged; Phenytoin; Propylamines; Sinoatrial Node; Verapamil; Wolff-Parkinson-White Syndrome	1973
[Therapy of arrhythmia in children]. Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1969, Volume: 35 Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Child; Humans; Male; Phenytoin; Phytotherapy; Plants, Medicinal; Propranolol; Rauwolfia; Sparteine; Tachycardia; Verapamil	1969
[Influence of active antiarrhythmia substances on refractory period and contractility of guinea pig atria]. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1969, Volume: 264, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Muscle Contraction; Nitriles; Phenytoin; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Reaction Time; Sparteine; Vasodilator Agents; Verapamil	1969
Actions of antiarrhythmic drugs on refractory period and contractility of isolated rat and guinea-pig atria. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 271, Issue:4 Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Ethers; Ethylamines; Glycerol; Guinea Pigs; Heart Atria; Lidocaine; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Rats; Sparteine; Verapamil	1971
[What is certain in the therapy of heart diseases?]. Der Internist, 1969, Volume: 10, Issue:12 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Output; Digitalis Glycosides; Drug Hypersensitivity; Endocarditis, Bacterial; Heart Diseases; Humans; Penicillins; Phenytoin; Procainamide; Propranolol; Rheumatic Heart Disease; Verapamil	1969
[Clinical pharmacology and adverse effects of various anti-arrhythmic drugs]. Deutsche medizinische Wochenschrift (1946), 1971, Apr-16, Volume: 96, Issue:16 Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Bone Marrow Diseases; Central Nervous System Diseases; Female; Gastrointestinal Diseases; Heart Diseases; Hemodynamics; Humans; Imidazoles; Isoproterenol; Lidocaine; Membrane Potentials; Phenytoin; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Verapamil	1971
[Action of antiarrhythmic and -receptor blocking drugs on functional refractory period and contractility of electrically stimulated guinea-pig atria]. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Atrial Function; Drug Interactions; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Reserpine; Sparteine; Sympatholytics; Time Factors; Verapamil	1971
[Action of anti-arrhythmia agents on intracardiac conduction]. Acta cardiologica, 1974, Volume: Suppl 18 Topics: Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Benzofurans; Bundle of His; Cardiac Catheterization; Depression, Chemical; Diethylamines; Dogs; Electrocardiography; Heart Conduction System; Indans; Iodobenzoates; Lidocaine; Lidoflazine; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1974
Action of antiarrhythmic drugs on His bundle electrogram and sinus node function. Acta cardiologica, 1974, Volume: Suppl 18 Topics: Action Potentials; Ajmaline; Aniline Compounds; Anti-Arrhythmia Agents; Benzyl Compounds; Bundle of His; Cardiac Catheterization; Diethylamines; Electrocardiography; Heart Block; Heart Conduction System; Heart Rate; Humans; Imidazoles; Indans; Phenytoin; Practolol; Sinoatrial Node; Sparteine; Verapamil	1974
Experimental evaluation of antiarrhythmic drugs in the guinea pig. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Jul-20, Volume: 19, Issue:7 Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Guinea Pigs; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine; Strophanthins; Verapamil	1973
[Effect of antiarrhythmics on intracardial excitation conduction in His-bundle electrography]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79 Topics: Ajmaline; Anti-Arrhythmia Agents; Heart Conduction System; Humans; Phenytoin; Practolol; Verapamil	1973
[The problems of paroxysmal auricular flutter with atrio-ventricular block (author's transl)]. Munchener medizinische Wochenschrift (1950), 1973, Oct-05, Volume: 115, Issue:40 Topics: Aged; Diagnosis, Differential; Digitalis Glycosides; Electrocardiography; Heart Block; Humans; Male; Phenytoin; Potassium; Propranolol; Tachycardia, Paroxysmal; Verapamil	1973
[Disturbances of cardiac rhythm and their treatment]. La Clinica terapeutica, 1970, Sep-15, Volume: 54, Issue:5 Topics: Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Digitoxin; Digoxin; Humans; Lidocaine; Metaproterenol; Middle Aged; Phenytoin; Procainamide; Quinidine; Reserpine; Verapamil	1970
[Differential therapy of tachycardial arrhythmias]. Deutsche medizinische Wochenschrift (1946), 1969, Apr-11, Volume: 94, Issue:15 Topics: Anti-Arrhythmia Agents; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Reserpine; Sparteine; Sympatholytics; Tachycardia; Tachycardia, Paroxysmal; Verapamil	1969
Management of cardiac drug overdose. Resuscitation, 1984, Volume: 11, Issue:3-4 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Humans; Phenytoin; Poison Control Centers; Verapamil	1984
Effect of trifluoperazine, D600, and phenytoin on depolarization- and thyrotropin-releasing hormone-induced thyrotropin release from rat pituitary tissue. Endocrinology, 1981, Volume: 108, Issue:6 Topics: Animals; Calcium; Gallopamil; Ion Channels; Male; Membrane Potentials; Phenytoin; Pituitary Gland, Anterior; Potassium; Rats; Sodium; Thyrotropin; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil; Veratridine	1981
[Quinidine interactions with propranolol, phenytoin, verapamil and procainamide]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1984, Jun-11, Volume: 39, Issue:24 Topics: Arrhythmias, Cardiac; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Humans; Male; Middle Aged; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil	1984
Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations. Japanese circulation journal, 1983, Volume: 47, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Dogs; Female; Lidocaine; Male; Mexiletine; Phenytoin; Verapamil	1983
[Emergency therapy of cardiac arrhythmias. Statistico-clinical evaluation of verapamil (clinical note)]. Minerva cardioangiologica, 1982, Volume: 30, Issue:4 Topics: Acute Disease; Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Bunaftine; Female; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Verapamil	1982
Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Dose-Response Relationship, Drug; Isoquinolines; Lidocaine; Ligation; Phenytoin; Propanolamines; Verapamil	1982
Some further observations on the stimulation by high external potassium of the sodium efflux in barnacle muscle fibers. Pflugers Archiv : European journal of physiology, 1982, Volume: 395, Issue:4 Topics: Animals; Chelating Agents; Fluorides; Imipramine; Muscles; Phenothiazines; Phenytoin; Potassium; Purine Nucleotides; Sodium; Stimulation, Chemical; Thoracica; Verapamil	1982
Advances in the diagnosis and treatment of tachydysrhythmias in children. American heart journal, 1981, Volume: 102, Issue:1 Topics: Ambulatory Care; Atrioventricular Node; Bundle of His; Child; Dose-Response Relationship, Drug; Electrocardiography; Exercise Test; Humans; Pacemaker, Artificial; Phenytoin; Propranolol; Tachycardia; Telephone; Ventricular Fibrillation; Verapamil; Wolff-Parkinson-White Syndrome	1981
Mechanism of grayanotoxin III-induced afterpotentials in feline cardiac Purkinje fibers. European journal of pharmacology, 1981, Nov-05, Volume: 75, Issue:4 Topics: Animals; Calcium; Cats; Diterpenes; Electric Stimulation; Female; Heart Conduction System; In Vitro Techniques; Male; Membrane Potentials; Phenytoin; Potassium; Purkinje Fibers; Verapamil	1981
Nifedipine for digitalis-induced arrhythmias. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jun-21, Volume: 57, Issue:25 Topics: Animals; Arrhythmias, Cardiac; Dogs; Nifedipine; Phenytoin; Pyridines; Strophanthins; Verapamil	1980
Inhibitory effect of calcium channel blockers on growth of pancreatic cancer cells. Pancreas, 1994, Volume: 9, Issue:2 Topics: Calcium Channel Blockers; Cell Division; Humans; Pancreatic Neoplasms; Phenytoin; Tumor Cells, Cultured; Verapamil	1994
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Molecular pharmacology, 1996, Volume: 49, Issue:2 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil	1996
Familial polymorphic ventricular arrhythmias: a quarter century of successful medical treatment based on serial exercise-pharmacologic testing. Journal of the American College of Cardiology, 1999, Volume: 34, Issue:7 Topics: Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anticonvulsants; Catecholamines; Child; Drug Administration Routes; Echocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follow-Up Studies; Heart Ventricles; Humans; Isoproterenol; Male; Middle Aged; Pedigree; Phenytoin; Propranolol; Retrospective Studies; Tachycardia, Ventricular; Treatment Outcome; Verapamil	1999
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil	2000
Comparative study of calcium-channel blockers on cell proliferation, DNA and collagen syntheses, and EGF receptors of cultured gingival fibroblasts derived from human nifedipine, nicardipine and nisoldipine responders. Journal of oral science, 2001, Volume: 43, Issue:4 Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Calcium Channel Blockers; Cell Culture Techniques; Cell Division; Collagen; Diltiazem; DNA; ErbB Receptors; Female; Fibroblasts; Flow Cytometry; Gingiva; Gingival Overgrowth; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Phenytoin; Radiopharmaceuticals; Statistics as Topic; Tritium; Verapamil	2001
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro. Neuroscience letters, 2008, Apr-04, Volume: 434, Issue:3 Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil	2008
In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein. Life sciences, 2010, Jun-05, Volume: 86, Issue:23-24 Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blood-Brain Barrier; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Rhodamine 123; Verapamil	2010
Study on in situ and in vivo absorption kinetics of phenytoin by modulating P-glycoprotein with verapamil in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2011, Sep-18, Volume: 44, Issue:1-2 Topics: Administration, Oral; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Ileum; Intestinal Absorption; Male; Perfusion; Permeability; Phenytoin; Propranolol; Rats; Rats, Wistar; Verapamil	2011
Effects of high frequency electrical stimulation and R-verapamil on seizure susceptibility and glutamate and GABA release in a model of phenytoin-resistant seizures. Neuropharmacology, 2011, Volume: 61, Issue:4 Topics: Animals; Disease Models, Animal; Disease Susceptibility; Drug Resistance; Electric Stimulation; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Stereoisomerism; Verapamil	2011
[Effect of anti-arrhythmia drugs on mouse arrhythmia induced by Bufonis Venenum]. Yao xue xue bao = Acta pharmaceutica Sinica, 2011, Volume: 46, Issue:10 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bufanolides; Electrocardiography; Female; Heart Rate; In Vitro Techniques; Lethal Dose 50; Lidocaine; Male; Mice; Phenytoin; Propranolol; Verapamil	2011
Verapamil effect on phenytoin pharmacokinetics in rats. Epilepsy research, 2013, Volume: 107, Issue:1-2 Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Drug Interactions; Female; Phenytoin; Rats; Rats, Sprague-Dawley; Verapamil	2013
P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy. Drug design, development and therapy, 2013, Volume: 7 Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Disease Models, Animal; Drug Resistance; Epilepsy; Male; Phenytoin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution; Up-Regulation; Verapamil	2013
Pharmacoproteomics-based reconstruction of in vivo P-glycoprotein function at blood-brain barrier and brain distribution of substrate verapamil in pentylenetetrazole-kindled epilepsy, spontaneous epilepsy, and phenytoin treatment models. Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:10 Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Disease Models, Animal; Epilepsy; Male; Membrane Proteins; Mice; Pentylenetetrazole; Phenytoin; Proteomics; Verapamil	2014
Reversal of P-glycoprotein overexpression by Ginkgo biloba extract in the brains of pentylenetetrazole-kindled and phenytoin-treated mice. The Kaohsiung journal of medical sciences, 2015, Volume: 31, Issue:8 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caspase 3; Disease Models, Animal; Ginkgo biloba; Kindling, Neurologic; Male; Mice; Pentylenetetrazole; Phenytoin; Plant Extracts; Seizures; Verapamil	2015
Silymarin as a flavonoid-type P-glycoprotein inhibitor with impact on the pharmacokinetics of carbamazepine, oxcarbazepine and phenytoin in rats. Drug and chemical toxicology, 2021, Volume: 44, Issue:5 Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Drug Interactions; Male; Oxcarbazepine; Phenytoin; Rats; Rats, Wistar; Silymarin; Tissue Distribution; Verapamil	2021
Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data. Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:4 Topics: Acetamides; Albuterol; Animals; Carbamates; Chromatography, Liquid; Diazepam; Diclofenac; Digitoxin; Humans; Itraconazole; Ketoprofen; Liver; Metabolic Clearance Rate; Mice; Mice, Transgenic; Naproxen; Pharmaceutical Preparations; Phenytoin; Piperidines; Pravastatin; Pyrimidines; Quinidine; Tandem Mass Spectrometry; Telmisartan; Terfenadine; Verapamil	2020