verapamil and oxybutynin

verapamil has been researched along with oxybutynin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bodner, DR; Leffler, E; Lindan, R; Resnick, MI1
Crema, A; D'Angelo, L; De Ponti, F; Del Vecchio, A; Perucca, E; Rizzi, CA; Tonini, M1
Constantinou, CE; Levounis, P1
Bulitta, M; Burmeister, S; Fröhlich, G; Wiedemann, A1
Kaneko, S; Nakano, D; Nishimori, T; Ohara, M1
Fujino Oki, T; Kato, Y; Kurosawa, S; Nanri, M; Uchida, S; Yamada, S; Yoshida, K1
El-Bahnasawy, MS; Gomha, MA; Nabeeh, A; Shaaban, H1

Reviews

1 review(s) available for verapamil and oxybutynin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for verapamil and oxybutynin

ArticleYear
The effect of verapamil on the treatment of detrusor hyperreflexia in the spinal cord injured population.
    Paraplegia, 1989, Volume: 27, Issue:5

    Topics: Adult; Calcium Channel Blockers; Female; Humans; Male; Mandelic Acids; Middle Aged; Reflex; Spinal Cord Injuries; Verapamil

1989
[Intravesical instillation of trospium chloride, oxybutynin and verapamil for relaxation of the bladder detrusor muscle. A placebo controlled, randomized clinical test].
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: Adult; Benzilates; Calcium Channel Blockers; Female; Humans; Injections; Male; Mandelic Acids; Muscle Relaxation; Muscle, Smooth; Nortropanes; Parasympatholytics; Single-Blind Method; Urinary Bladder; Urodynamics; Verapamil

1998
Clinical and urodynamic efficacy of oxybutynin and verapamil in the treatment of nocturnal enuresis after formation of orthotopic ileal neobladders. A prospective, randomized, crossover study.
    Scandinavian journal of urology and nephrology, 2008, Volume: 42, Issue:4

    Topics: Adult; Calcium Channel Blockers; Cholinergic Antagonists; Colonic Pouches; Cross-Over Studies; Cystectomy; Humans; Male; Mandelic Acids; Middle Aged; Muscle Contraction; Nocturnal Enuresis; Prospective Studies; Prostatectomy; Treatment Outcome; Verapamil

2008

Other Studies

12 other study(ies) available for verapamil and oxybutynin

ArticleYear
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Depressant action of oxybutynin on the contractility of intestinal and urinary tract smooth muscle.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:2

    Topics: Acetylcholine; Animals; Calcium Chloride; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Intestines; Male; Mandelic Acids; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Ureter; Urinary Bladder; Verapamil

1987
Analysis of the in vitro pharmacologic response of renal pelvis and detrusor smooth muscle to thiphenamil, oxybutynin and verapamil.
    Urologia internationalis, 1988, Volume: 43, Issue:4

    Topics: Animals; Diphenylacetic Acids; In Vitro Techniques; Kidney Pelvis; Male; Mandelic Acids; Muscle Contraction; Muscle, Smooth; Rabbits; Sulfur Compounds; Urinary Bladder; Verapamil

1988
[Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1999, Volume: 113, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Benzilates; Butylamines; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Potassium Chloride; Propantheline; Rats; Rats, Wistar; Urinary Bladder; Urination; Urination Disorders; Vasodilator Agents; Verapamil

1999
Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain.
    Life sciences, 2007, Jun-06, Volume: 80, Issue:26

    Topics: Analysis of Variance; Animals; Benzilates; Brain; Calcium Channels, L-Type; Diltiazem; Isradipine; Male; Mandelic Acids; N-Methylscopolamine; Protein Binding; Rats; Rats, Sprague-Dawley; Tritium; Urinary Bladder; Verapamil

2007