verapamil has been researched along with oxadiazoles in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (51.22) | 18.7374 |
| 1990's | 12 (29.27) | 18.2507 |
| 2000's | 5 (12.20) | 29.6817 |
| 2010's | 3 (7.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glossmann, H; Knaus, HG; Staudinger, R | 1 |
| Keith, RA; Moore, WC; Patel, J; Salama, AI | 1 |
| Naitoh, T; Sugimoto, T; Toyo-Oka, T | 1 |
| Murphy, BJ; Tuana, BS | 1 |
| Pinchuk, GV; Pinchuk, LN; Rudenko, AE; Tkachenko, YV | 1 |
| Jope, RS; Li, XH; Song, L | 1 |
| Asahina, T; Ikebuchi, M; Kashiwagi, A; Kodama, M; Nishio, Y; Ogawa, T; Shigeta, Y | 1 |
| Beaufort, P; Chatelain, P; Clinet, M; Laruel, R; Meysmans, L; Nokin, P | 1 |
| Harada, Y; Kimura, R; Nakayama, K; Yamada, S | 1 |
| Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Benavides, J; Bertrand, P; Burgevin, MC; Doble, A; Ferris, O; Gueremy, C; Le Fur, G; Menager, J; Uzan, A; Vaucher, N | 1 |
| Glossmann, H; Goll, A; Moosburger, K; Striessnig, J | 1 |
| Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A | 1 |
| Hofmann, F; Nastainczyk, W; Sieber, M; Wernet, W; Zubor, V | 1 |
| Becker, C; Kokubun, S; Porzig, H; Prod'hom, B; Reuter, H | 1 |
| Highsmith, RF; Schwartz, A; Whitmer, KR; Williams-Lawson, JS | 1 |
| Becker, C; Porzig, H | 1 |
| Dunn, SM | 2 |
| Dillon, JS; Gu, XH; Nayler, WG | 1 |
| Dillon, JS; Gu, XH; Liu, JJ; Nayler, WG | 1 |
| Hudecová, S; Krizanová, O; Orlický, J; Zachar, J | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
| Garcia, L; Lazdunski, M; Rieger, F; Romey, G | 1 |
| Hof, RP | 1 |
| Cook, NS; Hof, RP | 1 |
| Bevan, JA; Hwa, JJ | 1 |
| Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H | 1 |
| Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M | 1 |
| Reynolds, IJ; Snowman, AM; Snyder, SH | 1 |
| Dakshinamurti, K; Lal, KJ | 1 |
| Ehrenstein, G; Fitzpatrick, LA; Pocotte, SL | 1 |
| Baltrons, MA; García, A; Pedraza, CE | 1 |
| Ertunc, M; Onur, R; Sara, Y | 1 |
| Adaikan, PG; Lau, LC | 1 |
| Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK | 1 |
| Bankar, GR; Chamallamudi, MR; Nampurath, GK; Nandakumar, K; Nayak, PG; Thakur, A | 1 |
| Kito, Y; Suzuki, H | 1 |
| Alexander, SP; Garle, MJ; Randall, MD; Roberts, RE; Wong, PS | 1 |
| Busch, M; Busch, R; Dörr, M; Eckerle, LG; Felix, SB; Gross, S; Hertrich, I; Rauch, BH; Reinke, Y; Riad, A; Stasch, JP | 1 |
41 other study(ies) available for verapamil and oxadiazoles
| Article | Year |
|---|---|
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil | 1991 |
Role of calcium in regulation of phosphoinositide signaling pathway.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbachol; Cations, Divalent; Cells, Cultured; Cerebral Cortex; Diltiazem; Egtazic Acid; Inositol; Inositol Phosphates; Isradipine; Kinetics; Models, Neurological; Neurons; Oxadiazoles; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Signal Transduction; Sulfonamides; Verapamil | 1991 |
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil | 1990 |
Calcium ions inhibit the allosteric interaction between the dihydropyridine and phenylalkylamine binding site on the voltage-gated calcium channel in heart sarcolemma but not in skeletal muscle transverse tubules.
Topics: Allosteric Regulation; Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Heart; In Vitro Techniques; Isradipine; Kinetics; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Rabbits; Receptors, Nicotinic; Sarcolemma; Verapamil | 1990 |
Calcium channel ligand binding to intact, concanavalin A and cyclic AMP-treated cells of the immune system.
Topics: Animals; Bucladesine; Calcium Channels; Concanavalin A; Isradipine; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Mice, Inbred CBA; Nitrendipine; Oxadiazoles; Spleen; Verapamil | 1990 |
Modulation of phosphoinositide metabolism in rat brain slices by excitatory amino acids, arachidonic acid, and GABA.
Topics: Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Calcium; Carbachol; Egtazic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrolysis; Kinetics; Male; Manganese; Norepinephrine; Oxadiazoles; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Quisqualic Acid; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Increase in [3H]PN 200-110 binding to cardiac muscle membrane in streptozocin-induced diabetic rats.
Topics: Animals; Binding Sites; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Isradipine; Male; Membranes; Myocardium; Oxadiazoles; Rats; Rats, Inbred Strains; Streptozocin; Tritium; Verapamil | 1990 |
SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Indolizines; Isradipine; Male; Myocardium; Oxadiazoles; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Sarcolemma; Verapamil | 1990 |
Calcium channel receptor sites for (+)-[3H]PN 200-110 in coronary artery.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Coronary Vessels; Diltiazem; Edetic Acid; Female; In Vitro Techniques; Isradipine; Kinetics; Male; Oxadiazoles; Receptors, Nicotinic; Swine; Verapamil | 1990 |
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1990 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
Dihydropyridine and peripheral type benzodiazepine binding sites: subcellular distribution and molecular size determination.
Topics: Animals; Benzodiazepinones; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dogs; Ion Channels; Isoquinolines; Isradipine; Male; Molecular Weight; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Nicotinic; Sarcolemma; Sarcoplasmic Reticulum; Verapamil | 1985 |
Purified calcium channels have three allosterically coupled drug receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1986 |
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil | 1986 |
The 165-kDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel.
Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Verapamil | 1987 |
Voltage-dependent cooperative interactions of calcium channel ligands in intact cardiac cells.
Topics: Allosteric Site; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Ion Channels; Kinetics; Membrane Potentials; Myocardium; Nicotinic Acids; Oxadiazoles; Rats; Verapamil | 1987 |
Effect of calcium channel modulators on isolated endothelial cells.
Topics: Adenosine Triphosphate; Animals; Benzofurans; Biological Products; Bradykinin; Calcium; Carbachol; Cattle; Diltiazem; Endothelium; Fura-2; Ion Channels; Isradipine; Nitric Oxide; Oxadiazoles; Thrombin; Verapamil | 1988 |
Potential-dependent allosteric modulation of 1,4-dihydropyridine binding by d-(cis)-diltiazem and (+/-)-verapamil in living cardiac cells.
Topics: Allosteric Regulation; Animals; Calcium; Diltiazem; Heart; In Vitro Techniques; Ion Channels; Isradipine; Membrane Potentials; Myocardium; Oxadiazoles; Rats; Sarcolemma; Verapamil | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydropyridines; Indicators and Reagents; Isradipine; Male; Myocardium; Oxadiazoles; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Nicotinic; Time Factors; Verapamil | 1989 |
The failure of endothelin to displace bound, radioactively-labelled, calcium antagonists (PN 200/110, D888 and diltiazem).
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endothelins; Female; In Vitro Techniques; Isradipine; Oxadiazoles; Peptides; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil | 1989 |
Is Ca2+ antagonists binding protein from cytosolic fraction the precursor of alpha 1-subunit of Ca2+ channel?
Topics: Affinity Labels; Animals; Antibodies; Azides; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cytoplasm; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Oxadiazoles; Protein Precursors; Rabbits; Radioligand Assay; Receptors, Nicotinic; Ultraviolet Rays; Verapamil | 1989 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Isradipine; Mice; Muscle Contraction; Oxadiazoles; Piperidines; Thiazines; Verapamil | 1988 |
Interaction between two calcium antagonists and two beta blockers in conscious rabbits: hemodynamic consequences of differing cardiodepressant properties.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Consciousness; Drug Interactions; Hemodynamics; Humans; Isradipine; Oxadiazoles; Pindolol; Propranolol; Rabbits; Verapamil | 1987 |
Cardioprotection by the calcium antagonist PN 200-110 in the absence and presence of cardiodepression.
Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; In Vitro Techniques; Isradipine; Myocardial Contraction; Myocardium; Oxadiazoles; Rabbits; Time Factors; Verapamil | 1985 |
A nimodipine-resistant Ca2+ pathway is involved in myogenic tone in a resistance artery.
Topics: Analysis of Variance; Animals; Arteries; Calcium; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance; Isradipine; Male; Manganese; Muscle, Smooth, Vascular; Nicotinic Acids; Nimodipine; Oxadiazoles; Potassium; Rabbits; Vascular Resistance; Verapamil | 1986 |
A novel high affinity class of Ca2+ channel blockers.
Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil | 1988 |
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.
Topics: Affinity Labels; Animals; Autoradiography; Benzazepines; Bepridil; Binding, Competitive; Calcium Channels; Diltiazem; Isradipine; Kinetics; Muscles; Oxadiazoles; Photochemistry; Pyrrolidines; Rabbits; Receptors, Nicotinic; Verapamil | 1986 |
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.
Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil | 1986 |
Calcium channels in vitamin B6 deficiency-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Diltiazem; Hypertension; Male; Nicotinic Acids; Nifedipine; Oxadiazoles; Rats; Rats, Sprague-Dawley; Verapamil; Vitamin B 6 Deficiency | 1993 |
Role of calcium channels in parathyroid hormone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cattle; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Ionomycin; Isotope Labeling; Nicotinic Acids; Nifedipine; Oxadiazoles; Parathyroid Glands; Parathyroid Hormone; Pertussis Toxin; Phosphorylation; Potassium; Radioimmunoassay; Stereoisomerism; Verapamil; Virulence Factors, Bordetella | 1995 |
Interleukin-1beta stimulates cyclic GMP efflux in brain astrocytes.
Topics: Animals; Astrocytes; Biological Transport; Brain; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Interleukin-1; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxadiazoles; Probenecid; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Verapamil | 2001 |
The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.
Topics: Animals; Caffeine; Diaphragm; Endotoxemia; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indazoles; Lipopolysaccharides; Male; Muscle Contraction; Neuromuscular Nondepolarizing Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Ryanodine; Tubocurarine; Vasodilator Agents; Verapamil | 2004 |
Mechanisms of direct relaxant effect of sildenafil, tadalafil and vardenafil on corpus cavernosum.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium; Carbolines; Dose-Response Relationship, Drug; Imidazoles; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Oxadiazoles; Penis; Phosphodiesterase Inhibitors; Piperazines; Purines; Quinoxalines; Rabbits; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Verapamil | 2006 |
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil | 2006 |
Vasorelaxant effect in rat aortic rings through calcium channel blockage: a preliminary in vitro assessment of a 1,3,4-oxadiazole derivative.
Topics: Animals; Aorta; Calcium Channel Blockers; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Norepinephrine; Oxadiazoles; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Vasodilation; Verapamil | 2009 |
Properties of Rikkunshi-to (TJ-43)-induced relaxation of rat gastric fundus smooth muscles.
Topics: Animals; Apamin; Drugs, Chinese Herbal; Enprostil; Gastric Fundus; Hesperidin; Membrane Potentials; Muscle Relaxation; Muscle, Smooth; Oxadiazoles; Potassium; Pyrimidinones; Quinoxalines; Rats; Thiazoles; Verapamil | 2010 |
A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries.
Topics: Animals; Bradykinin; Carbenoxolone; Catalase; Colforsin; Coronary Vessels; Female; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Ouabain; Oxadiazoles; Peptides; Polyethylene Glycols; Quinoxalines; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents; Vasodilation; Verapamil | 2014 |
The soluble guanylate cyclase stimulator riociguat and the soluble guanylate cyclase activator cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats.
Topics: Animals; Benzoates; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Female; Guanylate Cyclase; Isoproterenol; Muscle Relaxation; Myocardial Contraction; Myocytes, Cardiac; Oxadiazoles; Pyrazoles; Pyrimidines; Quinoxalines; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Thionucleotides; Verapamil | 2015 |