verapamil and nortriptyline

verapamil has been researched along with nortriptyline in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's2 (6.45)18.2507
2000's10 (32.26)29.6817
2010's15 (48.39)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Dansette, PM; Fontana, E; Poli, SM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bredehoeft, SJ; Chaturvedi, AK; Hidding, JT; Rao, NG; Smith, JC1
Jamali, F; Mehvar, R1
Kaplan, B; Swain, RA1
Ejsing, TB; Hasselstrøm, J; Linnet, K1
Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y1
Cai, L; Li, L; Liu, J; Peng, W; Yang, J; Yang, S; Zhang, Q1
Bhatt, J; Djalilian, HR; Ghavami, Y; Haidar, YM; Lin, HW; Moshtaghi, O; Ziai, KN1
Djalilian, HR; Haidar, YM; Lin, HW; Mahboubi, H; Moshtaghi, O; Sahyouni, R1
Djalilian, HR; Ghavami, Y; Haidar, YM; Lin, HW; Moshtaghi, O1
Abouzari, M; Djalilian, HR; Ghavami, Y; Goshtasbi, K; Lin, HW; Parker, EM; Sarna, B; Tan, D1
Donaldson, L; Dornhoffer, JR; Liu, YF; Macias, D; Rizk, HG1

Reviews

4 review(s) available for verapamil and nortriptyline

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Bioequivalence of chiral drugs. Stereospecific versus non-stereospecific methods.
    Clinical pharmacokinetics, 1997, Volume: 33, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Area Under Curve; Computer Simulation; Disopyramide; Doxepin; Drug Interactions; Flurbiprofen; Food-Drug Interactions; Guidelines as Topic; Hydroxychloroquine; Ibuprofen; Nadolol; Nortriptyline; Propafenone; Stereoisomerism; Therapeutic Equivalency; Verapamil

1997
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
    Southern medical journal, 1997, Volume: 90, Issue:9

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Chronic Disease; Cluster Headache; Dihydroergotamine; Female; GABA Agents; Headache; Humans; Male; Migraine Disorders; Nortriptyline; Physical Exertion; Psychomotor Performance; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sports; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil

1997

Other Studies

27 other study(ies) available for verapamil and nortriptyline

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Two tricyclic antidepressant poisonings: levels of amitriptyline, nortriptyline and desipramine in post-mortem biological samples.
    Forensic science international, 1987, Volume: 33, Issue:2

    Topics: Adult; Amitriptyline; Chromatography, High Pressure Liquid; Desipramine; Humans; Male; Nortriptyline; Suicide; Verapamil

1987
The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites.
    Drug metabolism and drug interactions, 2006, Volume: 21, Issue:3-4

    Topics: Adenosine Triphosphatases; Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cyclosporine; Drug Interactions; Enzyme Inhibitors; Liver; Male; Methadone; Mice; Mice, Knockout; Nortriptyline; Rats; Rats, Wistar; Verapamil

2006
Pharmacophore modeling for hERG channel facilitation.
    Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1

    Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis

2012
[Effect of piperine on metablism and distribution of nortriptyline in mice].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:4

    Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Male; Mice; Nortriptyline; Piperidines; Polyunsaturated Alkamides; Tandem Mass Spectrometry; Verapamil

2014
Management of mal de debarquement syndrome as vestibular migraines.
    The Laryngoscope, 2017, Volume: 127, Issue:7

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Fructose; Genetic Predisposition to Disease; Humans; Male; Meniere Disease; Middle Aged; Migraine Disorders; Motion Sickness; Nortriptyline; Prospective Studies; Quality of Life; Topiramate; Travel; Travel-Related Illness; Verapamil; Visual Analog Scale

2017
Resolution of Persistent Post-Stapedotomy Vertigo With Migraine Prophylactic Medication.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2017, Volume: 38, Issue:10

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Calcium Channel Blockers; Diet; Female; Humans; Life Style; Male; Middle Aged; Nortriptyline; Postoperative Complications; Retrospective Studies; Stapes Surgery; Verapamil; Vertigo

2017
Evaluating Quality of Life in Patients With Meniere's Disease Treated as Migraine.
    The Annals of otology, rhinology, and laryngology, 2018, Volume: 127, Issue:12

    Topics: Chemoprevention; Female; Fructose; Humans; Male; Meniere Disease; Middle Aged; Migraine Disorders; Nortriptyline; Patient Reported Outcome Measures; Psychotropic Drugs; Quality of Life; Risk Reduction Behavior; Surveys and Questionnaires; Topiramate; Vasodilator Agents; Verapamil

2018
Efficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients.
    The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Female; Follow-Up Studies; Hearing; Hearing Tests; Humans; Hyperacusis; Male; Middle Aged; Migraine Disorders; Nortriptyline; Prospective Studies; Quality of Life; Topiramate; Treatment Outcome; Vasodilator Agents; Verapamil; Visual Analog Scale; Young Adult

2020
Pharmacotherapy failure and progression to botulinum toxin injection in vestibular migraine.
    The Journal of laryngology and otology, 2020, Volume: 134, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Botulinum Toxins; Dizziness; Female; Humans; Injections; Male; Middle Aged; Migraine Disorders; Nortriptyline; Propranolol; Retrospective Studies; Risk Factors; Topiramate; Treatment Failure; Verapamil; Young Adult

2020