verapamil has been researched along with naloxone in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (23.64) | 18.7374 |
| 1990's | 14 (25.45) | 18.2507 |
| 2000's | 13 (23.64) | 29.6817 |
| 2010's | 13 (23.64) | 24.3611 |
| 2020's | 2 (3.64) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Barlow, D; Ciarlo, L; Dimmito, MP; Houseknecht, KL; Lei, W; Macedonio, G; Mollica, A; Novellino, E; Pieretti, S; Stefanucci, A; Streicher, JM | 1 |
| Espinoza, M; Flores, R; Ortiz, S; Schnur, P; Vallejos, S; Wainwright, M | 1 |
| Akaike, M; Hirai, M; Kumai, T; Masubuchi, Y; Tanaka, M; Watanabe, M | 1 |
| Schnur, P | 1 |
| Fukumitsu, K; Hayashi, Y; Kinouchi, K; Sumikawa, K; Yoshiya, I | 1 |
| Baeyens, JM; Barrios, M | 2 |
| Rabkin, SW | 1 |
| Lopez, J; Naujokat, P; Toledo-Pereyra, LH; Walters, W; Xavier, R | 1 |
| Chang, PL; Dixon, WR | 1 |
| Fich, A; Hanson, RB; Neri, M; Phillips, SF; Zinsmeister, AR | 1 |
| Fóris, G; Hauck, M; Medgyesi, GA | 1 |
| Kavaliers, M | 1 |
| Kavaliers, M; Ossenkopp, KP | 1 |
| Bongianni, F; Carla, V; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Alailima, ST; Simpkins, CO; Tate, EA | 1 |
| Brase, DA; Dewey, WL; Lux, F; Welch, SP | 1 |
| Heath, A; Knudsen, K; Ricksten, SE | 1 |
| Camarri, F; Carcangiu, P; Fratta, W; Gessa, GL; Marrosu, F; Mereu, G | 1 |
| Culver, PJ; Rattan, S | 1 |
| Baeyens, JM; Esposito, E; Ossowska, G; Samanin, R | 1 |
| Brasch, H | 1 |
| Bondesson, L; Lundeberg, T; Lundström, V | 1 |
| Huang, TF; Lee, YM; Sheu, JR; Yen, MH | 1 |
| Lasova, LS; Mutafova-Yambolieva, VN; Venkova, KM | 1 |
| Miranda, HF; Pelissier, T; Sierralta, F | 1 |
| Almeida, OF; Deicke, J; Fischer, D; Gärtner, P; Hassan, AH; Hellbach, S | 1 |
| Li, HD; Li, XC; Ruan, HZ | 1 |
| Blackburn-Munro, G; Brown, CH; Landgraf, R; Neumann, ID; Russell, JA | 1 |
| Epple, HJ; Fromm, M; Riecken, EO; Schulzke, JD | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Dake, Y; Fukazawa, Y; Kishioka, S; Maeda, T; Ozaki, M; Shimizu, N; Yamamoto, C; Yamamoto, H | 1 |
| Dkhar, SA; Naveen, AT; Peddyreddy, MK; Ramaswamy, S; Shewade, DG | 1 |
| Chung, YK; Jeong, YS; Kim, C; Lee, HK; Park, KE; Shin, IW; Sohn, JT | 1 |
| Itoh, Z; Koga, H; Omura, S; Ozaki, K; Takanashi, H; Yogo, K | 1 |
| Christians, U; Elkiweri, IA; Henthorn, TK; Ng, KY; Tissot van Patot, MC; Zhang, YL | 1 |
| Benjamin Guise, J; Bickel, W; Brooks Gentry, W; Cargile, C; Mancino, M; Oliveto, A; Sanders, N | 1 |
| Du, W; Duan, Y; Jin, L; Liang, J; Meng, Y; Shen, F; Sui, N; Zhang, J | 1 |
1 review(s) available for verapamil and naloxone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for verapamil and naloxone
| Article | Year |
|---|---|
Relief of primary dysmenorrhea by transcutaneous electrical nerve stimulation.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dysmenorrhea; Electric Stimulation Therapy; Female; Humans; Naloxone; Pain; Pain Management; Transcutaneous Electric Nerve Stimulation; Verapamil | 1985 |
Effects of prototypic calcium channel blockers in methadone-maintained humans responding under a naloxone discrimination procedure.
Topics: Adult; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Methadone; Middle Aged; Naloxone; Self Report; Substance Withdrawal Syndrome; Verapamil | 2013 |
52 other study(ies) available for verapamil and naloxone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.
Topics: Administration, Intravenous; Analgesics, Opioid; Animals; CHO Cells; Cricetulus; Female; Humans; Infusions, Subcutaneous; Male; Mice; Models, Molecular; Opioid Peptides; Pain; Peptides, Cyclic; Receptors, Opioid | 2020 |
Blocking naloxone-precipitated withdrawal in rats and hamsters.
Topics: Animals; Behavior, Animal; Clonidine; Cricetinae; Drug Implants; Mesocricetus; Morphine Dependence; Naloxone; Nifedipine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Verapamil; Yawning | 1992 |
Disturbance or relatively important actions of antihypertensives, antifungal agent and opiate antagonist to the testicular steroidogenesis in rat.
Topics: Androstenedione; Animals; Antifungal Agents; Antihypertensive Agents; Clonidine; Estradiol; Ketoconazole; Male; Naloxone; Narcotic Antagonists; Prazosin; Rats; Testis; Testosterone; Verapamil | 1992 |
Morphine withdrawal in the hamster.
Topics: Animals; Clonidine; Cricetinae; Morphine; Naloxone; Nifedipine; Stereotyped Behavior; Substance Withdrawal Syndrome; Verapamil | 1992 |
Pentazocine-induced catecholamine efflux from the dog perfused adrenals.
Topics: Acetylcholine; Adrenal Glands; Animals; Catecholamines; Dogs; Dopamine beta-Hydroxylase; Female; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Naloxone; Pentazocine; Verapamil | 1991 |
Differential effects of L-type calcium channel blockers and stimulants on naloxone-precipitated withdrawal in mice acutely dependent on morphine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Mice; Morphine Dependence; Naloxone; Nicardipine; Postural Balance; Substance Withdrawal Syndrome; Verapamil | 1991 |
Diltiazem and verapamil lower blood pressure in the unanaesthetized rat through CNS mechanisms involving endogenous opioids.
Topics: Animals; Blood Pressure; Brain; Consciousness; Diltiazem; Endorphins; Heart Rate; Injections, Intraventricular; Naloxone; Rats; Rats, Inbred Strains; Time Factors; Verapamil | 1991 |
Role of opioid antagonists in the rat liver ischemia model.
Topics: Animals; Calcium Channel Blockers; Hepatic Artery; Ischemia; Liver; Nalbuphine; Naloxone; Naltrexone; Narcotic Antagonists; Portal Vein; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Changes in cardiovascular responses of conscious rats to endogenous opioids following treatment with catecholamine-depleting agents.
Topics: Animals; Atropine; Blood Pressure; Cardiovascular Physiological Phenomena; Catecholamines; Dynorphins; Endorphins; Enkephalin, Methionine; Heart Rate; Hydroxydopamines; Male; Motor Activity; Naloxone; Narcotics; Neurotoxins; Oxidopamine; Peptide Fragments; Rats; Rats, Inbred Strains; Reserpine; Verapamil | 1990 |
Regulation of postprandial motility in the canine ileum.
Topics: Animals; Atropine; Dogs; Eating; Fasting; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Ileum; Manometry; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Prostaglandins H; Verapamil | 1990 |
Bidirectional effect of met-enkephalin on macrophage effector functions.
Topics: Adenylyl Cyclases; Animals; Antibody-Dependent Cell Cytotoxicity; Calcium; Cyclic AMP; Cyclic GMP; Endopeptidases; Enkephalin, Methionine; Guanylate Cyclase; Ion Channels; Macrophages; Male; Naloxone; Neprilysin; Phagocytosis; Rats; Rats, Inbred Strains; Receptors, Fc; Receptors, IgG; Sodium; Verapamil | 1986 |
Stimulatory influences of calcium channel antagonists on stress-induced opioid analgesia and locomotor activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immobilization; Mice; Mice, Inbred C57BL; Motor Activity; Naloxone; Nifedipine; Pain; Reaction Time; Stress, Physiological; Verapamil | 1987 |
Magnetic fields inhibit opioid-mediated 'analgesic' behaviours of the terrestrial snail, Cepaea nemoralis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Diltiazem; Ion Channels; Magnetics; Morphine; Naloxone; Nifedipine; Nociceptors; Pyrrolidines; Snails; Temperature; Verapamil | 1988 |
Differential effects of calcium channel blockers and stimulants on morphine withdrawal in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Diltiazem; Ethanol; Female; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Rats; Rats, Inbred Strains; Stereoisomerism; Substance Withdrawal Syndrome; Verapamil | 1988 |
Calcium channel inhibitors suppress the morphine-withdrawal syndrome in rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Methoxyhydroxyphenylglycol; Morphine; Morphine Dependence; Naloxone; Nicotinic Acids; Nimodipine; Norepinephrine; Rats; Receptors, Opioid; Substance Withdrawal Syndrome; Verapamil | 1986 |
Inhibition by naloxone of neutrophil superoxide release: a potentially useful antiinflammatory effect.
Topics: Binding, Competitive; Calcium; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Naloxone; Neutrophils; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Opioid; Superoxides; Verapamil | 1986 |
Interaction of morphine with intrathecally administered calcium and calcium antagonists: evidence for supraspinal endogenous opioid mediation of intrathecal calcium-induced antinociception in mice.
Topics: Analgesics; Animals; Calcium; Egtazic Acid; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Naloxone; Verapamil | 1988 |
Effects of naloxone and verapamil in experimental amitriptyline poisoning in rats.
Topics: Amitriptyline; Animals; Antidotes; Blood Pressure; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Naloxone; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Different epileptogenic activities of murine and ovine corticotropin-releasing factor.
Topics: Animals; Corticotropin-Releasing Hormone; Electroencephalography; Epilepsy; Injections, Intraventricular; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Sheep; Species Specificity; Verapamil | 1987 |
Influence of loperamide on the internal anal sphincter in the opossum.
Topics: Anal Canal; Animals; Drug Interactions; Electric Stimulation; Female; Isoproterenol; Loperamide; Male; Naloxone; Nicotine; Opossums; Piperidines; Pressure; Rectum; Spinal Nerve Roots; Verapamil | 1987 |
Effects of peripheral and central administration of calcium channel blockers in the naloxone-precipitated abstinence syndrome in morphine-dependent rats.
Topics: Animals; Body Weight; Brain; Calcium Channel Blockers; Clonidine; Diarrhea; Flunarizine; Injections, Intraventricular; Male; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome; Verapamil | 1987 |
Influence of the optical isomers (+)- and (-)-naloxone on beating frequency, contractile force and action potentials of guinea-pig isolated cardiac preparations.
Topics: Action Potentials; Animals; Depression, Chemical; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; Isomerism; Male; Membrane Potentials; Morphine; Myocardial Contraction; Naloxone; Potassium; Verapamil | 1986 |
Effect of naloxone on platelet aggregation in rats.
Topics: Animals; Aspirin; Blood Pressure; Dose-Response Relationship, Drug; Naloxone; Osmolar Concentration; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Verapamil | 1994 |
Atrial natriuretic peptide inhibits the purinergic and not the adrenergic component of electrically induced contractile responses in guinea pig vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Naloxone; Neurotransmitter Agents; Nitrendipine; Phenylephrine; Prazosin; Receptors, Adrenergic; Receptors, Purinergic; Vas Deferens; Verapamil; Yohimbine | 1993 |
Analgesic effects of intracerebroventricular administration of calcium channel blockers in mice.
Topics: Analgesics; Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Injections, Intraventricular; Mice; Naloxone; Pain Measurement; Pain Threshold; Piperazines; Verapamil | 1993 |
Inherent glucocorticoid response potential of isolated hypothalamic neuroendocrine neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; beta-Endorphin; Calcium; Cells, Cultured; Coculture Techniques; Corticotropin-Releasing Hormone; Culture Media, Serum-Free; Dexamethasone; Glucocorticoids; Kinetics; Male; Mifepristone; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Verapamil; Veratridine | 1998 |
[Effect of corticotropin on formalin-evoked c-fos expression of spinal cord and receptors analysis in rat].
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium Channel Blockers; Formaldehyde; Naloxone; Narcotic Antagonists; Phentolamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Opioid; Spinal Cord; Verapamil | 1998 |
Verapamil prevents withdrawal excitation of oxytocin neurones in morphine-dependent rats.
Topics: Animals; Animals, Suckling; Calcium Channel Blockers; Calcium Channels, L-Type; Electric Stimulation; Female; Hypertonic Solutions; Injections, Intraventricular; Lactation; Membrane Potentials; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Oxytocin; Pituitary Gland; Rats; Rats, Sprague-Dawley; Sincalide; Substance Withdrawal Syndrome; Succinimides; Supraoptic Nucleus; Verapamil | 2000 |
Antisecretory effect of loperamide in colon epithelial cells by inhibition of basolateral K+ conductance.
Topics: Antidiarrheals; Calcium Channel Blockers; Calmodulin; Carbachol; Chlorides; Cholinergic Agonists; Colforsin; Colon; Drug Evaluation, Preclinical; Enterocytes; HT29 Cells; Humans; Intestinal Mucosa; Loperamide; Naloxone; Narcotic Antagonists; Potassium Channels; Signal Transduction; Time Factors; Trifluoperazine; Verapamil | 2001 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
Involvement of peripheral mechanism in the verapamil-induced potentiation of morphine analgesia in mice.
Topics: Analgesics, Opioid; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Corticosterone; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Naloxone; Pain Measurement; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Verapamil | 2004 |
An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice.
Topics: Animals; Atropine; Calcium Channels; Clonidine; Gastrointestinal Transit; Glyburide; Insulin; Insulin Secretion; Intestine, Small; Male; Mice; Naloxone; Ondansetron; Receptors, Opioid; Verapamil | 2006 |
Alfentanil attenuates phenylephrine-induced contraction in rat aorta.
Topics: Alfentanil; Analgesics, Opioid; Animals; Aorta; Calcium Channel Blockers; Cardiotonic Agents; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Naloxone; Narcotic Antagonists; Phenylephrine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Verapamil | 2007 |
In vitro pharmacological characterization of mitemcinal (GM-611), the first acid-resistant non-peptide motilin receptor agonist, in smooth muscle of rabbit small intestine.
Topics: Acetylcholine; Animals; Atropine; Binding, Competitive; Calcium Chloride; Diltiazem; Dose-Response Relationship, Drug; Erythromycin; Hexamethonium; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Intestine, Small; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Tetrodotoxin; Tropisetron; Verapamil | 2007 |
Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats.
Topics: Analgesics, Opioid; Animals; ATP Binding Cassette Transporter, Subfamily B; Binding, Competitive; Brain; Electroencephalography; Fentanyl; Infusions, Intravenous; Loperamide; Lung; Male; Models, Biological; Naloxone; Organic Anion Transporters; Pravastatin; Rats; Rats, Sprague-Dawley; Tissue Distribution; Verapamil | 2009 |
Distinctive roles of L-type calcium channels subtypes within the dorsal hippocampus in formation of morphine withdrawal-induced aversion in rats.
Topics: Animals; Avoidance Learning; Calcium Channels, L-Type; Hippocampus; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Substance Withdrawal Syndrome; Verapamil | 2023 |