verapamil has been researched along with mitoxantrone in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (9.76) | 18.7374 |
| 1990's | 12 (29.27) | 18.2507 |
| 2000's | 12 (29.27) | 29.6817 |
| 2010's | 13 (31.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Burkett, BA; Chan, KF; Chan, TH; Chow, LM; Wong, IL; Zhao, Y | 1 |
| Go, ML; Liu, XL; Tee, HW | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Delmer, A; Helou, C; Marie, JP; Thevenin, D; Zittoun, R | 1 |
| Cowan, KH; Dixon, KH; Horton, J; Kelley, K; Morrow, C; Nakagawa, M; Schneider, E | 1 |
| Djaldetti, M; Gilgal, R; Klein, B; Sheinberg, A; Zahavi, I | 1 |
| Cantwell, BM; Harris, AL; Hendrick, AM | 1 |
| Glüsenkamp, KH; Jähde, E; Rajewsky, MF | 1 |
| Appelt, M; Büchner, T; Eichelbaum, M; Grille, W; Hiddemann, W; Hossfeld, DK; Koslowski, B; Kraft, J; Kuse, R; Quabeck, K | 1 |
| Lai, T; Morgan, AP; Smith, PJ; Symes, MO | 1 |
| Advani, SH; Chitnis, MP; Pradhan, SG; Satyamoorthy, K | 1 |
| Durr, FE; Lindh, D; Wallace, RE | 1 |
| Boyse, O; Gibby, EM; Hill, BT | 1 |
| Cheng, YC; Ferguson, PJ | 1 |
| Chen, JW; He, RG; Qiu, WL | 1 |
| Di Simone, D; Grassi, B; Malvaldi, G; Mattii, L; Petrini, M; Testi, R; Zaccaro, L | 1 |
| Faussat, AM; Marie, JP; Simonin, G; Zhou, DC; Zittoun, R | 1 |
| Andreeff, M; Beran, M; Consoli, U; Mahadevia, R; Neamati, N; Van, NT; Zhao, S | 1 |
| Berti, E; Berti, T; Carrara, M; D'Ancona, S; Ragazzi, E | 1 |
| Bates, SE; Honjo, Y; Litman, T; Miyake, K; Regis, JT; Robey, RW; van de Laar, A | 1 |
| Bates, SE; Dietel, M; Hohenberger, P; Jordan, A; Lage, H; Litman, T; Stein, U; Walther, W | 1 |
| Elliott, JI; Higgins, CF; Raguz, S | 1 |
| Sikic, BI | 1 |
| de Grouw, EP; de Witte, TJ; Jansen, JH; Raaijmakers, MH; Raymakers, RA; van der Reijden, BA | 1 |
| Behar-Cohen, F; Bourasset, F; Chapy, H; Cisternino, S; Declèves, X; Saubaméa, B; Scherrmann, JM; Tournier, N | 1 |
| Asghar, S; Chen, Z; Gao, S; Huang, L; Ping, Q; Xiao, Y; Xu, Y; Yin, L | 1 |
| Dong, Y; Duan, Y; Fu, H; Gong, K; Liao, H; Wang, Q; Yu, J | 1 |
3 review(s) available for verapamil and mitoxantrone
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Multidrug resistance and stem cells in acute myeloid leukemia.
Topics: ADP-ribosyl Cyclase 1; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bone Marrow Cells; Cyclosporins; Drug Resistance, Multiple; Gene Expression Profiling; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Reverse Transcriptase Polymerase Chain Reaction; Verapamil | 2006 |
2 trial(s) available for verapamil and mitoxantrone
| Article | Year |
|---|---|
Verapamil with mitoxantrone for advanced ovarian cancer: a negative phase II trial.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Feasibility Studies; Female; Humans; Middle Aged; Mitoxantrone; Ovarian Neoplasms; Verapamil | 1991 |
Effects of verapamil on anthracycline-induced cardiomyopathy: preliminary results of a prospective multicenter trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cytarabine; Daunorubicin; Hemodynamics; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Thioguanine; Verapamil | 1990 |
36 other study(ies) available for verapamil and mitoxantrone
| Article | Year |
|---|---|
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Flavonoid dimers as bivalent modulators for P-glycoprotein-based multidrug resistance: synthetic apigenin homodimers linked with defined-length poly(ethylene glycol) spacers increase drug retention and enhance chemosensitivity in resistant cancer cells.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Apigenin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Dimerization; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Mice; Paclitaxel; Polyethylene Glycols; Structure-Activity Relationship; Vinblastine | 2006 |
Functionalized chalcones as selective inhibitors of P-glycoprotein and breast cancer resistance protein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Line, Tumor; Chalcones; Drug Resistance, Neoplasm; Electrons; Humans; Neoplasm Proteins; Small Molecule Libraries; Structure-Activity Relationship | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML).
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cefoperazone; Cyclosporine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Membrane Glycoproteins; Middle Aged; Mitoxantrone; Stem Cells; Tumor Cells, Cultured; Verapamil | 1992 |
Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells.
Topics: Adenosine Triphosphate; Antibodies; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cell Membrane Permeability; Cross Reactions; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Humans; Intracellular Fluid; Membrane Glycoproteins; Membrane Proteins; Mitoxantrone; Tumor Cells, Cultured; Verapamil | 1992 |
Effect of anthracycline drugs on the element content of cultured embryonic rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Antibiotics, Antineoplastic; Calcium Radioisotopes; Cells, Cultured; Doxorubicin; Elements; Epirubicin; Female; Heart; Microchemistry; Mitoxantrone; Myocardium; Pregnancy; Rats; Rats, Inbred Strains; Verapamil; X-Ray Diffraction | 1991 |
Protection of cultured malignant cells from mitoxantrone cytotoxicity by low extracellular pH: a possible mechanism for chemoresistance in vivo.
Topics: Animals; Cell Survival; Drug Resistance; Extracellular Space; Hydrogen-Ion Concentration; Mammary Neoplasms, Experimental; Mitoxantrone; Rats; Tumor Cells, Cultured; Verapamil | 1990 |
The effect of verapamil on the anti-tumour action of mitozantrone and doxorubicin against renal carcinoma cells in vitro.
Topics: Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Humans; Kidney Neoplasms; Mitoxantrone; Neoplasm Proteins; Selenomethionine; Tumor Cells, Cultured; Verapamil | 1990 |
Modulation of mitoxantrone cytotoxicity by verapamil in human chronic myeloid leukemia cells.
Topics: DNA; Drug Synergism; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mitoxantrone; Tumor Cells, Cultured; Verapamil | 1989 |
Development of resistance and characteristics of a human colon carcinoma subline resistant to mitoxantrone in vitro.
Topics: 2,4-Dinitrophenol; Carcinoma; Cell Nucleus; Colonic Neoplasms; Dinitrophenols; DNA, Neoplasm; Drug Resistance; Humans; Mitoxantrone; Polysorbates; Tumor Cells, Cultured; Verapamil | 1987 |
Selective interactions of verapamil with anthraquinones in adriamycin-sensitive and -resistant murine and human tumour cell lines in vitro.
Topics: Cell Survival; Colony-Forming Units Assay; Doxorubicin; Drug Interactions; Female; Humans; Mitoxantrone; Ovarian Neoplasms; Verapamil | 1987 |
Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Etoposide; Humans; Methotrexate; Mitoxantrone; Nasopharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases; Verapamil; Vincristine | 1987 |
[Verapamil enhancement of antitumor effect of mitoxantrone on ACC-2 cell line in vitro and in vivo].
Topics: Animals; Carcinoma, Adenoid Cystic; DNA, Neoplasm; Drug Synergism; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitoxantrone; Neoplasm Transplantation; Salivary Gland Neoplasms; Salivary Glands, Minor; Tumor Cells, Cultured; Verapamil | 1994 |
Evaluation of resistance index of several anticancer agents on parental and resistant P-388 cell lines.
Topics: Animals; Biological Transport; DNA Replication; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Epirubicin; Idarubicin; In Vitro Techniques; Leukemia P388; Mice; Mitoxantrone; Tumor Cells, Cultured; Verapamil | 1995 |
Effect of the multidrug inhibitor GG918 on drug sensitivity of human leukemic cells.
Topics: Acridines; Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane Permeability; Drug Resistance, Multiple; Gene Expression; Humans; Idarubicin; Isoquinolines; Leukemia; Mitoxantrone; RNA, Messenger; RNA, Neoplasm; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1997 |
Cellular pharmacology of mitoxantrone in p-glycoprotein-positive and -negative human myeloid leukemic cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Multiple; Flow Cytometry; HL-60 Cells; Humans; Microscopy, Confocal; Mitoxantrone; Polymerase Chain Reaction; Tumor Cells, Cultured; Verapamil | 1997 |
A comparison of the modulation of antiblastics cytotoxicity by verapamil and dipyridamole in a human colon carcinoma cell line.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Colonic Neoplasms; Cyclophosphamide; Dipyridamole; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; Idarubicin; Mitoxantrone; Neoplasm Proteins; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine | 1999 |
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Boron Compounds; Breast Neoplasms; Cell Survival; Colonic Neoplasms; Drug Resistance, Multiple; Female; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Humans; Intracellular Membranes; Kinetics; Microsomes; Mitoxantrone; Neoplasm Proteins; Polymerase Chain Reaction; Prazosin; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Verapamil | 2001 |
Impact of BCRP/MXR, MRP1 and MDR1/P-Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; DNA Primers; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Multiple; Fluorescent Dyes; Gastrointestinal Neoplasms; Gene Expression Regulation; Genes, MDR; Hot Temperature; Humans; Indenes; Mitoxantrone; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein; Mycotoxins; Neoplasm Proteins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; RNA, Neoplasm; Stomach Neoplasms; Verapamil | 2002 |
Multidrug transporter activity in lymphocytes.
Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; B-Lymphocytes; Calcium Channel Blockers; Fluoresceins; Fluorescent Dyes; Lymphocytes; Mice; Mice, Knockout; Mitoxantrone; Multidrug Resistance-Associated Proteins; Paclitaxel; Prazosin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Verapamil; Xanthenes | 2004 |
ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.
Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Aged; Antigens, CD34; Antigens, Differentiation; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bone Marrow Cells; Cyclosporins; Drug Resistance, Multiple; Female; Flow Cytometry; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Oncogene Proteins, Fusion; Reverse Transcriptase Polymerase Chain Reaction; Verapamil | 2006 |
Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier.
Topics: Animals; ATP-Binding Cassette Transporters; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Male; Mice, Knockout; Mitoxantrone; Verapamil; Zidovudine | 2016 |
Polysaccharide-based nanoparticles for co-loading mitoxantrone and verapamil to overcome multidrug resistance in breast tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mitoxantrone; Nanoparticles; Polyelectrolytes; Verapamil | 2017 |
Incorporation of drug efflux inhibitor and chemotherapeutic agent into an inorganic/organic platform for the effective treatment of multidrug resistant breast cancer.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Calcium Phosphates; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Drug Compounding; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Humans; Mice, Inbred BALB C; Mice, Nude; Mitoxantrone; Molecular Targeted Therapy; Nanocapsules; Oligopeptides; Phosphatidylserines; Polyethylene Glycols; Verapamil | 2019 |