verapamil and mibefradil

verapamil has been researched along with mibefradil in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.38)	18.7374
1990's	31 (36.90)	18.2507
2000's	39 (46.43)	29.6817
2010's	12 (14.29)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Keserü, GM	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Li, J; Rajamani, R; Reynolds, CH; Tounge, BA	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Dansette, PM; Fontana, E; Poli, SM	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Caron, G; Ermondi, G; Visentin, S	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Billman, GE	1
Fang, LM; Osterrieder, W	1
Clozel, JP; Hess, P; Véniant, M; Wolfgang, R	1
Clozel, JP; Osterrieder, W; Véniant, M	1
Clozel, JP; Hefti, F; Osterrieder, W	1
Holck, M; Osterrieder, W	1
Banken, L; Clozel, JP; Osterrieder, W	1
Blaheta, RA; Encke, A; Hailer, NP; Harder, S; Markus, BH; Scholz, M	1
Bosse, E; Flockerzi, V; Hofmann, F; Lacinová, L; Ludwig, A	1
Blanc, T; Richard, V; Thuillez, C; Tron, C	1
Bosse, E; Flockerzi, V; Hofmann, F; Lacinová, L; Ruth, P; Welling, A	1
Bühler, FR; Clozel, JP; Iberg, N; Schmitt, R	1
Bosse, E; Donatin, K; Flockerzi, V; Hofmann, F; Lacinova, L; Ludwig, A; Welling, A	1
Reimer, KA; Schwartz, LM; Vander Heide, RS	1
Hermsmeyer, K; Mishra, SK	1
Birnbaumer, L; Hofmann, F; Ito, H; Klugbauer, N; Lacinová, L; Schuster, A	1
Billman, GE; Hamlin, RL	1
Bochkov, VN; Ratner, EI; Tkachuk, VA	1
Böhm, M; Cremers, B; Flesch, M; Südkamp, M	1
Pitt, B	1
Conlin, PR; Williams, GH	1
Lüscher, TF; Noll, G	1
Hofmann, D; McCarthy, J; Muller, CA; Opie, LH; Peisach, M; Pineda, CA	1
Mak, IT; Mason, PE; Mason, RP; Tulenko, TN; Walter, MF	1
Barhanin, J; Chouabe, C; Drici, MD; Lazdunski, M; Romey, G	1
Angus, JA; Fujiwara, T; Molenaar, P; Sarsero, D	1
Duffield, R; Ho, AK; Tang, T	1
Backenköhler, U; Dörge, H; Heusch, G; Jalowy, A; Post, H; Schulz, R; Vahlhaus, C	1
Brust, PF; Hans, M; Harpold, MM; Prodanovich, P; Stauderman, KA; Urrutia, A; Washburn, MS; Williams, ME	1
Behrends, M; Heusch, G; Schulz, R	1
Curtis, MJ; Farkas, A; Qureshi, A	1
Meissner, A; Min, JY; Sandmann, S; Simon, R; Unger, T	1
Bénardeau, A; Ertel, EA; Hondeghem, L; Weissenburger, J	1
De Mey, JG; Pfaffendorf, M; van der Lee, R; van Zwieten, PA	1
Göthert, M; Likungu, J; Molderings, GJ	1
Dumont, L; Jasmin, G; Paquette, F	1
Mathy, MJ; Pfaffendorf, M; van der Lee, R; van Zwieten, PA	1
Joseph, JA; Wang, H	1
Ceric, F; Kerr, B; Kong, M; Morales, P; Pizarro, E; Vigil, P	1
Avdonin, PV; Buhler, FR; Tkachuk, VA	1
Budihna, MV; Grasic Kuhar, C	1
Benquet, P; Frere, S; Pichon, Y; Tiaho, F	1
Claas, R; Cleutjens, JP; Daemen, MJ; Sandmann, S; Unger, T	1
Meissner, A; Min, JY; Morgan, JP; Wang, J	1
Lijnen, PJ	1
Holzhausen, C; Nebe, B; Rychly, J; Urbaszek, W	1
Beltrame, JF; Horowitz, JD; Leslie, S; Turner, SP	1
Connolly, TM; Figueroa, DJ; Lawlor, AM; Liang, HA; Liu, Y; Salata, JJ; Xia, M	1
Budihna, MV; Grasic Kuhar, C; Pleskovic, RZ	1
Savoia, C; Schiffrin, EL; Tabet, F; Touyz, RM	1
Jacobson, TA	1
Badawi, JK; Bross, S; Kamp, S; Kwon, ST; Langbein, S; Li, H	1
Chen, YC; Lin, T; Nagpal, ML; Stocco, DM	1
Meissner, A; Noack, T	1
Jenkins, J; Moldobaeva, A; Wagner, E	1
Perez-Reyes, E; Van Deusen, AL; Vitko, I	1
Ball, CJ; Beltrame, JF; Saint, DA; Turner, SP; Wilson, DP	1
Godfraind, T	1
Bieger, D; Ford, CA; Tabrizchi, R	1
Hayashi, Y; Kawabata, A; Kubo, L; Matsunami, M; Miki, T; Nishikawa, H; Nishiura, K; Okawa, Y; Ozaki, T; Sekiguchi, F; Tsujiuchi, T	1
Inaba, K; Kutsuzawa, M; Shiba, K; Takahashi, T; Takayama-Watanabe, E; Watanabe, A	1
Chan, KW; Chow, LM; Choy, KY; Lear, MJ; Lee, YQ; Loh, CC; Nosten, FH; Rénia, L; Russell, B; Suwanarusk, R; Tan, KS	1

Reviews

4 review(s) available for verapamil and mibefradil

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005
Diversity of calcium antagonists. Clinical therapeutics, 1997, Volume: 19 Suppl A Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Kidney Failure, Chronic; Mibefradil; Nifedipine; Tetrahydronaphthalenes; Verapamil	1997
Use of calcium channel blockers in hypertension. Advances in internal medicine, 1998, Volume: 43 Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Heart Diseases; Humans; Hypertension; Longitudinal Studies; Mibefradil; Nifedipine; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil	1998
Comparative pharmacological properties among calcium channel blockers: T-channel versus L-channel blockade. Cardiology, 1998, Volume: 89 Suppl 1 Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Electrocardiography; Hemodynamics; Humans; Mibefradil; Tetrahydronaphthalenes; Verapamil	1998

Trials

1 trial(s) available for verapamil and mibefradil

Article	Year
Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. The American journal of cardiology, 2004, Nov-01, Volume: 94, Issue:9 Topics: Adolescent; Adult; Anticholesteremic Agents; Antiprotozoal Agents; Area Under Curve; Atorvastatin; Biomarkers; Calcium Channel Blockers; Clarithromycin; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Itraconazole; Male; Mibefradil; Middle Aged; Pravastatin; Protein Synthesis Inhibitors; Pyrroles; Simvastatin; Verapamil	2004

Article

Year

Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors.

The American journal of cardiology, 2004, Nov-01, Volume: 94, Issue:9

Topics: Adolescent; Adult; Anticholesteremic Agents; Antiprotozoal Agents; Area Under Curve; Atorvastatin; Biomarkers; Calcium Channel Blockers; Clarithromycin; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Itraconazole; Male; Mibefradil; Middle Aged; Pravastatin; Protein Synthesis Inhibitors; Pyrroles; Simvastatin; Verapamil

2004

Other Studies

79 other study(ies) available for verapamil and mibefradil

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers. Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18 Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2002
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
A two-state homology model of the hERG K+ channel: application to ligand binding. Bioorganic & medicinal chemistry letters, 2005, Mar-15, Volume: 15, Issue:6 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation	2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Ro 40-5967, a novel calcium channel antagonist, protects against ventricular fibrillation. European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3 Topics: Animals; Benzimidazoles; Binding Sites; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Disease Susceptibility; Dogs; Dose-Response Relationship, Drug; Heart Rate; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Physical Exertion; Tetrahydronaphthalenes; Ventricular Fibrillation; Verapamil	1992
Potential-dependent inhibition of cardiac Ca2+ inward currents by Ro 40-5967 and verapamil: relation to negative inotropy. European journal of pharmacology, 1991, Apr-17, Volume: 196, Issue:2 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Depression, Chemical; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Mibefradil; Myocardial Contraction; Tetrahydronaphthalenes; Verapamil	1991
Hemodynamic profile of Ro 40-5967 in conscious rats: comparison with diltiazem, verapamil, and amlodipine. Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10 Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Male; Mibefradil; Nifedipine; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil	1991
The structurally novel Ca2+ channel blocker Ro 40-5967, which binds to the [3H] desmethoxyverapamil receptor, is devoid of the negative inotropic effects of verapamil in normal and failing rat hearts. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Coronary Circulation; Depression, Chemical; Dose-Response Relationship, Drug; Female; Heart; Heart Failure; Hemodynamics; Male; Mibefradil; Myocardial Contraction; Myocardial Infarction; Rats; Rats, Inbred WKY; Receptors, Nicotinic; Tetrahydronaphthalenes; Tritium; Verapamil	1990
Antihypertensive properties of the novel calcium antagonist (1S,2S)-2-[2-[[3-(2-benzimidazolyl)propyl]methylamino] ethyl]-6- fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride in rat models of hypertension. Comparison with ver Arzneimittel-Forschung, 1990, Volume: 40, Issue:4 Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Heart Rate; Hypertension; Male; Mibefradil; Naphthalenes; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Tetrahydronaphthalenes; Verapamil	1990
In vitro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blocker with potent vasodilator but weak inotropic action. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:5 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Coronary Circulation; Electric Stimulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Mibefradil; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Naphthalenes; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil	1989
Effects of Ro 40-5967, a novel calcium antagonist, on myocardial function during ischemia induced by lowering coronary perfusion pressure in dogs: comparison with verapamil. Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:5 Topics: Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Dogs; Heart; Injections, Intravenous; Mibefradil; Tetrahydronaphthalenes; Verapamil	1989
Modulation of adhesion molecule expression on endothelial cells by verapamil and other Ca++ channel blockers. Immunobiology, 1994, Volume: 191, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzimidazoles; Calcium Channel Blockers; Calmodulin; Cell Adhesion Molecules; Cells, Cultured; Diltiazem; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Isoquinolines; Mibefradil; Piperazines; Protein Kinase C; Sulfonamides; Tetrahydronaphthalenes; Umbilical Veins; Vascular Cell Adhesion Molecule-1; Verapamil	1994
The block of the expressed L-type calcium channel is modulated by the beta 3 subunit. FEBS letters, 1995, Oct-09, Volume: 373, Issue:2 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; CHO Cells; Cricetinae; Feedback; Gallopamil; Gene Expression; Intracellular Membranes; Isradipine; Macromolecular Substances; Membrane Potentials; Mibefradil; Microsomes; Myocardium; Rabbits; Recombinant Proteins; Structure-Activity Relationship; Tetrahydronaphthalenes; Transfection; Verapamil	1995
Infarct size-limiting properties of Ro 40-5967, a novel nondihydropyridine calcium channel, in anesthetized rats: comparison with verapamil. Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:4 Topics: Anesthesia; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hemodynamics; Male; Mibefradil; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Tetrahydronaphthalenes; Verapamil	1995
Interaction of Ro 40-5967 and verapamil with the stably expressed alpha 1-subunit of the cardiac L-type calcium channel. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:1 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; CHO Cells; Cloning, Molecular; Cricetinae; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Mibefradil; Myocardium; Tetrahydronaphthalenes; Verapamil	1995
Mibefradil prevents neointima formation after vascular injury in rats. Possible role of the blockade of the T-type voltage-operated calcium channel. Arteriosclerosis, thrombosis, and vascular biology, 1995, Volume: 15, Issue:8 Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Carotid Artery Injuries; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Membrane Potentials; Mibefradil; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrahydronaphthalenes; Tunica Intima; Verapamil	1995
Expression of the L-type calcium channel with two different beta subunits and its modulation by Ro 40-5967. Pflugers Archiv : European journal of physiology, 1995, Volume: 429, Issue:3 Topics: Animals; Antibodies, Monoclonal; Benzimidazoles; Calcium Channel Blockers; Calcium Channels; CHO Cells; Cricetinae; Electrophysiology; Isradipine; Mibefradil; Muscle, Smooth; Stereoisomerism; Tetrahydronaphthalenes; Transfection; Verapamil	1995
The novel calcium antagonist Ro 40-5967 limits myocardial infarct size in the dog. Cardiovascular research, 1994, Volume: 28, Issue:10 Topics: Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Dogs; Female; Heart; Heart Rate; Male; Mibefradil; Myocardial Infarction; Myocardial Ischemia; Myocardium; Tetrahydronaphthalenes; Verapamil	1994
Inhibition of signal Ca2+ in dog coronary arterial vascular muscle cells by Ro 40-5967. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:1 Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Cells, Cultured; Coronary Vessels; Diltiazem; Dogs; Fluorometry; Mibefradil; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Potassium; Rats; Tetrahydronaphthalenes; Verapamil	1994
The IVS6 segment of the L-type calcium channel is critical for the action of dihydropyridines and phenylalkylamines. The EMBO journal, 1996, May-15, Volume: 15, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Benzimidazoles; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Humans; Ion Channel Gating; Isradipine; Mibefradil; Molecular Sequence Data; Muscle Proteins; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Tetrahydronaphthalenes; Transfection; Verapamil	1996
The effects of mibefradil, a novel calcium channel antagonist on ventricular arrhythmias induced by myocardial ischemia and programmed electrical stimulation. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:3 Topics: Animals; Arrhythmias, Cardiac; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrocardiography; Heart Ventricles; Mibefradil; Myocardial Ischemia; Tetrahydronaphthalenes; Verapamil	1996
Comparison of binding of 3H-desmethoxyverapamil and 3H-mibefradil in vascular smooth muscle and heart membranes. Possible binding of mibefradil to a site distinct from the phenylalkylamine-binding site. Arzneimittel-Forschung, 1996, Volume: 46, Issue:10 Topics: Animals; Benzimidazoles; Binding Sites; Calcium Channel Blockers; Cattle; Humans; In Vitro Techniques; Membranes; Mibefradil; Muscle, Smooth, Vascular; Myocardium; Tetrahydronaphthalenes; Verapamil	1996
Effects of the novel T-type calcium channel antagonist mibefradil on human myocardial contractility in comparison with nifedipine and verapamil. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:5 Topics: Benzimidazoles; Calcium Channel Blockers; Electric Stimulation; Heart Ventricles; Humans; In Vitro Techniques; Mibefradil; Myocardial Contraction; Nifedipine; Papillary Muscles; Tetrahydronaphthalenes; Verapamil	1997
Effects of mibefradil, a novel calcium channel blocking agent with T-type activity, in acute experimental myocardial ischemia: maintenance of ventricular fibrillation threshold without inotropic compromise. Journal of the American College of Cardiology, 1998, Volume: 32, Issue:1 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electrocardiography; Heart Ventricles; Infusions, Intravenous; Male; Mibefradil; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Swine; Tetrahydronaphthalenes; Ventricular Fibrillation; Verapamil	1998
Antioxidant and cytoprotective activities of the calcium channel blocker mibefradil. Biochemical pharmacology, 1998, Jun-01, Volume: 55, Issue:11 Topics: Animals; Antioxidants; Aorta; Benzimidazoles; Calcium Channel Blockers; Cattle; Cell Survival; Cells, Cultured; Endothelium, Vascular; Hydroxyl Radical; Lipid Bilayers; Lipid Peroxidation; Mibefradil; Myocardium; Oxidation-Reduction; Tetrahydronaphthalenes; Verapamil; X-Ray Diffraction	1998
HERG and KvLQT1/IsK, the cardiac K+ channels involved in long QT syndromes, are targets for calcium channel blockers. Molecular pharmacology, 1998, Volume: 54, Issue:4 Topics: Animals; Benzimidazoles; Bepridil; Calcium Channel Blockers; Cloning, Molecular; COS Cells; Heart; Ion Channel Gating; Long QT Syndrome; Membrane Potentials; Mibefradil; Potassium Channels; Tetrahydronaphthalenes; Transfection; Verapamil	1998
Human vascular to cardiac tissue selectivity of L- and T-type calcium channel antagonists. British journal of pharmacology, 1998, Volume: 125, Issue:1 Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Humans; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Vasa Vasorum; Verapamil	1998
Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic inhibition and hyperkalemia in cardiomyocytes. European journal of pharmacology, 1998, Nov-06, Volume: 360, Issue:2-3 Topics: Animals; Benzimidazoles; Calcium; Calcium Channel Blockers; Cells, Cultured; Chickens; Cyanides; Hyperkalemia; Mibefradil; Myocardium; Potassium; Potassium Chloride; Ryanodine; Tetrahydronaphthalenes; Verapamil	1998
Unique cardioprotective action of the new calcium antagonist mibefradil. Circulation, 1999, Jan-19, Volume: 99, Issue:2 Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Glyburide; Heart; Heart Rate; Heart Ventricles; Mibefradil; Myocardial Infarction; Pressure; Swine; Tetrahydronaphthalenes; Verapamil	1999
Structure and functional characterization of a novel human low-voltage activated calcium channel. Journal of neurochemistry, 1999, Volume: 72, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Barium; Benzimidazoles; Blotting, Northern; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, T-Type; Cells, Cultured; Cloning, Molecular; Diuretics; DNA, Complementary; Electric Stimulation; Electrophysiology; Humans; Ion Channel Gating; Kidney; Kinetics; Membrane Potentials; Mibefradil; Molecular Sequence Data; Nickel; Nimodipine; Oocytes; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Tetrahydronaphthalenes; Transcription, Genetic; Verapamil; Xenopus	1999
Effects of verapamil and mibefradil on regional blood flow and function in normal and ischemic myocardium. Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:3 Topics: Benzimidazoles; Calcium Channel Blockers; Coronary Circulation; Heart Function Tests; Humans; Mibefradil; Myocardial Ischemia; Tetrahydronaphthalenes; Verapamil	1999
Inadequate ischaemia-selectivity limits the antiarrhythmic efficacy of mibefradil during regional ischaemia and reperfusion in the rat isolated perfused heart. British journal of pharmacology, 1999, Volume: 128, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Electrocardiography; Heart; Heart Ventricles; Hemodynamics; In Vitro Techniques; Male; Mibefradil; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Potassium; Random Allocation; Rats; Rats, Wistar; Ventricular Fibrillation; Verapamil	1999
Differential effects of mibefradil, verapamil, and amlodipine on myocardial function and intracellular Ca(2+) handling in rats with chronic myocardial infarction. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3 Topics: Adrenergic beta-Agonists; Aequorin; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Heart; Heart Function Tests; Hemodynamics; Isometric Contraction; Isoproterenol; Male; Mibefradil; Myocardial Contraction; Myocardial Infarction; Myocardium; Papillary Muscles; Rats; Rats, Wistar; Verapamil	1999
Effects of the T-type Ca(2+) channel blocker mibefradil on repolarization of guinea pig, rabbit, dog, monkey, and human cardiac tissue. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Female; Guinea Pigs; Heart; Heart Atria; Humans; In Vitro Techniques; Male; Mibefradil; Rabbits; Saimiri; Sotalol; Telemetry; Time Factors; Verapamil	2000
Inhibitory effect of mibefradil on contractions induced by sympathetic neurotransmitter release in the rat tail artery. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:1 Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Electric Stimulation; In Vitro Techniques; Male; Mibefradil; Muscle Contraction; Muscle, Smooth, Vascular; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Wistar; Regional Blood Flow; Sympathetic Nervous System; Tail; Verapamil	2000
N-Type calcium channels control sympathetic neurotransmission in human heart atrium. Circulation, 2000, Feb-01, Volume: 101, Issue:4 Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Calcium Channels, N-Type; Diltiazem; Electric Stimulation; Female; Heart; Heart Atria; Humans; Male; Mibefradil; Middle Aged; Norepinephrine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Sympathetic Nervous System; Synaptic Transmission; Verapamil	2000
Cardioprotective efficacy of verapamil and mibefradil in young UM-X7.1 cardiomyopathic hamsters. Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:6 Topics: Animals; Biomarkers; Calcinosis; Calcium Channel Blockers; Cardiomyopathies; Cardiovascular Agents; Cricetinae; Female; Heart; Male; Mibefradil; Muscle, Skeletal; Myocardium; Necrosis; Time Factors; Tongue; Verapamil	1999
Evidence for a sympatholytic effect of mibefradil in the pithed rat preparation. Journal of hypertension, 2000, Volume: 18, Issue:2 Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Decerebrate State; Electric Stimulation; Heart Rate; Male; Mibefradil; Norepinephrine; Rats; Rats, Wistar; Sympathetic Nervous System; Sympatholytics; Verapamil	2000
Mechanisms of hydrogen peroxide-induced calcium dysregulation in PC12 cells. Free radical biology & medicine, 2000, Apr-15, Volume: 28, Issue:8 Topics: 2,2'-Dipyridyl; Animals; Barbiturates; Calcium Channel Blockers; Calcium Signaling; Clonazepam; Disulfides; Dithiothreitol; Extracellular Space; Fluorescent Dyes; Glutathione; Hydrogen Peroxide; Image Processing, Computer-Assisted; Intracellular Fluid; Ion Transport; Isoxazoles; Membrane Potentials; Mibefradil; Mitochondria; omega-Conotoxin GVIA; Oxidants; Oxidation-Reduction; PC12 Cells; Rats; Sodium Channels; Sodium-Calcium Exchanger; Sulfhydryl Compounds; Tetrodotoxin; Thiourea; Verapamil	2000
Gonadotropin-releasing hormone-stimulated sperm binding to the human zona is mediated by a calcium influx. Biology of reproduction, 2000, Volume: 63, Issue:2 Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; Humans; Male; Mibefradil; Nifedipine; Pimozide; Sperm-Ovum Interactions; Spermatozoa; Verapamil; Zona Pellucida	2000
Ca2+-agonistic effect of a T-type Ca-channel blocker mibefradil (Ro 40-5967). Membrane & cell biology, 2000, Volume: 13, Issue:5 Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Coronary Vessels; Diltiazem; Mibefradil; Muscle, Smooth, Vascular; Swine; Verapamil	2000
Effects of mibefradil and verapamil on ischemic-reperfusion in the hearts of guinea pigs with acute renal failure. Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:5 Suppl Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Coronary Circulation; Female; Guinea Pigs; L-Lactate Dehydrogenase; Male; Mibefradil; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Verapamil	2000
Properties and development of calcium currents in embryonic cockroach neurons. Neuroscience letters, 2000, Nov-10, Volume: 294, Issue:1 Topics: Amiloride; Animals; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; In Vitro Techniques; Isradipine; Membrane Potentials; Mibefradil; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Periplaneta; Verapamil	2000
Calcium channel blockade limits cardiac remodeling and improves cardiac function in myocardial infarction-induced heart failure in rats. Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:1 Topics: Amlodipine; Animals; Calcium Channel Blockers; Heart Failure; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mibefradil; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Ventricular Remodeling; Verapamil	2001
Mibefradil improves beta-adrenergic responsiveness and intracellular Ca(2+) handling in hypertrophied rat myocardium. Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:5 Topics: Adrenergic beta-Agonists; Aequorin; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Injections; Intracellular Fluid; Isometric Contraction; Male; Mibefradil; Myocardial Contraction; Myocardium; Papillary Muscles; Rats; Rats, Inbred Lew; Verapamil	2002
Impaired mechanisms of leukocyte adhesion in vitro by the calcium channel antagonist mibefradil. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3 Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Adhesion; Humans; Leukocytes; Mibefradil; Verapamil	2002
Impaired mechanisms of leukocyte adhesion in vitro by the calcium channel antagonist mibefradil. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:3 Topics: Adult; Amlodipine; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; CD18 Antigens; Cell Adhesion; Cells, Cultured; Cytoskeleton; Female; Flow Cytometry; Granulocytes; Humans; L-Selectin; Leukocytes; Male; Mibefradil; Microscopy, Confocal; Verapamil	2002
Mibefradil: "Has the baby been thrown out with the bath water?". American heart journal, 2003, Volume: 146, Issue:1 Topics: Angina Pectoris; Calcium Channel Blockers; Calcium Channels, T-Type; Coronary Disease; Coronary Vessels; Drug and Narcotic Control; Humans; Mibefradil; Randomized Controlled Trials as Topic; Verapamil	2003
Functional expression of L- and T-type Ca2+ channels in murine HL-1 cells. Journal of molecular and cellular cardiology, 2004, Volume: 36, Issue:1 Topics: Animals; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Electric Conductivity; Heart Atria; Ion Transport; Mibefradil; Mice; Myocytes, Cardiac; Nimodipine; Patch-Clamp Techniques; Pimozide; Potassium; Verapamil	2004
Mibefradil is more effective than verapamil for restoring post-ischemic function of isolated hearts of guinea pigs with acute renal failure. European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3 Topics: Acute Kidney Injury; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Electrocardiography; Guinea Pigs; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mibefradil; Myocardial Reperfusion Injury; Myocardium; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Function, Left; Verapamil	2004
Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2 Topics: Aminoquinolines; Animals; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Calcium Signaling; Diltiazem; Dose-Response Relationship, Drug; Hydrogen Peroxide; Male; Mesenteric Arteries; Mibefradil; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Superoxides; Verapamil	2004
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle. European journal of clinical pharmacology, 2006, Volume: 62, Issue:5 Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Carbachol; Diltiazem; Female; Humans; In Vitro Techniques; Male; Mibefradil; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Potassium; Urinary Bladder; Verapamil	2006
Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells. The Journal of endocrinology, 2007, Volume: 192, Issue:3 Topics: Adenosine Triphosphatases; Animals; Calcium Channel Blockers; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Egtazic Acid; Estradiol; Fulvestrant; Genistein; Leydig Cells; Male; Mibefradil; Mice; Phosphoproteins; Phytoestrogens; Progesterone; Quercetin; Receptors, Estrogen; Resveratrol; RNA, Messenger; Stilbenes; Stimulation, Chemical; Vanadates; Verapamil	2007
Proliferation of human lens epithelial cells (HLE-B3) is inhibited by blocking of voltage-gated calcium channels. Pflugers Archiv : European journal of physiology, 2008, Volume: 457, Issue:1 Topics: Algorithms; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Electrophysiology; Epithelial Cells; Humans; Ion Channel Gating; Lens Capsule, Crystalline; Lens, Crystalline; Mibefradil; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; Verapamil	2008
Effects of distension on airway inflammation and venular P-selectin expression. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:5 Topics: Animals; Calcium Channels, T-Type; Cell Adhesion; Endothelial Cells; Gene Expression Regulation; In Vitro Techniques; Leukocytes; Male; Mibefradil; Mice; Mice, Inbred C57BL; Microscopy; P-Selectin; Pneumonia; Positive-Pressure Respiration; Pulmonary Veins; RNA, Messenger; Stress, Mechanical; Verapamil	2008
Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs. The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:2 Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Dihydropyridines; Humans; Mibefradil; Nitrophenols; Organophosphorus Compounds; Verapamil	2009
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 53, Issue:4 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Humans; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Vasoconstriction; Verapamil	2009
Is combined L- and T-channel blockade better than L-channel blockade in therapy? Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1 Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Drug Synergism; Humans; Hypertension; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Rats; Vasoconstriction; Verapamil	2009
Potassium-induced intermittent vasomotion in rat isolated pulmonary artery. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2011, Volume: 47, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Animals; Barium; Indoles; Male; Mibefradil; Nicardipine; Niflumic Acid; Potassium; Potassium Channels; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Verapamil	2011
Involvement of the endogenous hydrogen sulfide/Ca(v) 3.2 T-type Ca2+ channel pathway in cystitis-related bladder pain in mice. British journal of pharmacology, 2012, Volume: 167, Issue:4 Topics: Acetanilides; Animals; Benzimidazoles; Calcium Channel Blockers; Calcium Channels, T-Type; Cyclophosphamide; Cyclopropanes; Cystathionine gamma-Lyase; Cystitis; Disease Models, Animal; Female; Ganglia, Spinal; Hydrogen Sulfide; Mibefradil; Mice; Naphthalenes; Organ Size; Pain; Purines; Transient Receptor Potential Channels; TRPA1 Cation Channel; Urinary Bladder; Verapamil	2012
Distinct Ca2+ channels maintain a high motility state of the sperm that may be needed for penetration of egg jelly of the newt, Cynops pyrrhogaster. Development, growth & differentiation, 2013, Volume: 55, Issue:7 Topics: Acrosome Reaction; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Extracts; Female; Hypotonic Solutions; Male; Mibefradil; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nitrendipine; Ovum; Salamandridae; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Time Factors; Verapamil	2013
Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PloS one, 2014, Volume: 9, Issue:10 Topics: Adenosine Triphosphate; Animals; Biomarkers; Boron Compounds; Chloroquine; DNA Copy Number Variations; Drug Resistance; Fluorescent Dyes; Genes, Protozoan; Inhibitory Concentration 50; Mibefradil; Microsomes; Molecular Probe Techniques; Parasites; Plasmodium falciparum; Polymorphism, Genetic; Reproducibility of Results; Verapamil	2014