verapamil has been researched along with metoclopramide in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Andonova, K; Koev, D; Matrozov, P; Stoeva, I; Tcharaktchiev, D; Zacharieva, S | 1 |
| Hasegawa, J; Hirai, S; Hisatome, I; Kotake, H; Mashiba, H | 1 |
| Boscaro, M; D'Agostino, D; Mantero, F; Menegus, A; Murgia, A; Opocher, G; Rocco, S | 1 |
| Gunderson, CH | 1 |
| Jamieson, DD; Lander, J | 1 |
| Douglas, WW; Taraskevich, PS | 1 |
| Chinchilli, VM; Esinhart, JD | 1 |
| Dressman, J; Kubbinga, M; Langguth, P; Sediq, A | 1 |
| Anoshchenko, O; Storelli, F; Unadkat, JD | 1 |
3 review(s) available for verapamil and metoclopramide
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The impact of the EMA change in definition of "dose" on the BCS dose-solubility ratio: a review of the biowaiver monographs.
Topics: Biopharmaceutics; Humans; Metoclopramide; Solubility; Verapamil | 2014 |
2 trial(s) available for verapamil and metoclopramide
| Article | Year |
|---|---|
Effect of verapamil on renin-angiotensin-aldosterone system, urinary 6-keto prostaglandin F1 alpha and aldosterone response to metoclopramide in normal man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Humans; Male; Metoclopramide; Renin-Angiotensin System; Verapamil | 1989 |
Design and analysis of intra-subject variability in cross-over experiments.
Topics: Area Under Curve; Bronchodilator Agents; Clinical Trials as Topic; Cross-Over Studies; Ethanolamines; Forced Expiratory Volume; Formoterol Fumarate; Gastroesophageal Reflux; Humans; Likelihood Functions; Male; Metoclopramide; Models, Statistical; Randomized Controlled Trials as Topic; Reference Values; Reproducibility of Results; Research Design; Therapeutic Equivalency; Verapamil | 1996 |
22 other study(ies) available for verapamil and metoclopramide
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Inotropic effect of thyrotropin-releasing hormone on the guinea pig myocardium.
Topics: Action Potentials; Animals; Calcium; Calcium Channels; Cimetidine; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Kinetics; Manganese; Metoclopramide; Myocardial Contraction; Norepinephrine; Phentolamine; Potassium; Stimulation, Chemical; Thyrotropin-Releasing Hormone; Verapamil | 1988 |
Effect of verapamil on the aldosterone-stimulating properties of metoclopramide: in vitro and in vivo studies.
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Animals; Female; Humans; In Vitro Techniques; Metoclopramide; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Management of the migraine patient.
Topics: Amitriptyline; Analgesics; Diagnosis, Differential; Diet; Ergotamine; Humans; Hypnotics and Sedatives; Methysergide; Metoclopramide; Migraine Disorders; Oxygen; Propranolol; Stress, Physiological; Verapamil | 1986 |
Investigation of the mode of action of the anaesthetic agent, ketamine, in the heart of the bivalve mollusc Tapes watlingi.
Topics: Acetylcholine; Amphetamine; Animals; Dose-Response Relationship, Drug; Heart; Heart Rate; Ketamine; Methysergide; Metoclopramide; Mollusca; Phentolamine; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1984 |
Slowing effects of dopamine and calcium-channel blockers on frequency of sodium spikes in rat pars intermedia cells.
Topics: Action Potentials; Animals; Calcimycin; Calcium; Cations, Divalent; Dopamine; In Vitro Techniques; Ion Channels; Male; Metoclopramide; Nifedipine; Pituitary Gland; Potassium; Rats; Rats, Inbred Strains; Verapamil | 1982 |
Successful Prediction of Human Steady-State Unbound Brain-to-Plasma Concentration Ratio of P-gp Substrates Using the Proteomics-Informed Relative Expression Factor Approach.
Topics: Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Brain Chemistry; Dogs; Endothelial Cells; Extracellular Fluid; Forecasting; Gene Expression Regulation; Humans; Loperamide; Madin Darby Canine Kidney Cells; Metoclopramide; Positron-Emission Tomography; Proteomics; Verapamil | 2021 |