verapamil has been researched along with melphalan in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (25.00) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 5 (20.83) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Balzarini, J; Baráth, Z; Das, U; De Clercq, E; Dimmock, JR; Kawase, M; Molnár, J; Ocsovszki, I; Panda, AK; Pati, HN; Sakagami, H; Zhou, L | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Das, S; Das, U; Dimmock, JR; Gorecki, DK; Iwamoto, S; Kawase, M; Matsuta, T; Molnár, J; Sakagami, H; Serly, J; Umemura, N | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Arnold, LA; Balakrishnan, K; Chen, W; Fan, H; Fan, Y; Gandhi, V; Peng, X; Sun, H; Wang, Y | 1 |
| Ardiet, C; Navarro, C; Sapet, C; Tranchand, B | 1 |
| Adams, GE; Godden, J; Howells, N; Stratford, IJ | 1 |
| Bell, JB; Gore, ME; Maitland, JA; McElwain, TJ; Millar, BC; Selby, PJ; Zuiable, A | 1 |
| Clutterbuck, RD; McElwain, TJ; Millar, JL; Robinson, BA | 2 |
| Ozols, RF | 1 |
| Averill-Bates, DA; Courtemanche, B | 1 |
| De Marco, C; Gornati, D; Silvestrini, R; Villa, R; Zaffaroni, N | 1 |
| Animati, F; Bigioni, M; Lombardi, P; Manzini, S; Palma, C; Pratesi, G; Salvatore, C; Supino, R; Zunino, F | 1 |
| Dmoszyńska, A; Sokołowska, B; Walter-Croneck, A; Wojtaszko, M | 1 |
| Chikhale, PJ; Killian, DM | 1 |
| Fujiwara, D; Imano, M; Itoh, T; Komai, M; Mashimo, K; Mukai, J; Nishida, S; Ogawa, N; Sakaguchi, K; Sakamoto, K; Satou, T; Shimaoka, H; Takeda, T; Tsubaki, M | 1 |
| Abraham, K; Abruzzo, T; Correa, ZM; Geller, JI; Karani, KB; Racadio, JM; Vadivelu, S; Zhang, B | 1 |
1 review(s) available for verapamil and melphalan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
23 other study(ies) available for verapamil and melphalan
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance.
Topics: Animals; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Inhibitory Concentration 50; Male; Mice; Molecular Structure; Neoplasms; Oxides; Quantitative Structure-Activity Relationship; Quinoxalines | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dimerization; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Piperidones | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents.
Topics: Antineoplastic Agents, Alkylating; Boronic Acids; Cell Line, Tumor; Drug Design; Esters; Humans; Hydrogen Peroxide; Nitrogen Mustard Compounds | 2018 |
[Cellular pharmacokinetics of melphalan alone or in combination on human lymphoma or lymphoblasts].
Topics: Antimetabolites; Blastomeres; Burkitt Lymphoma; Buthionine Sulfoximine; Cell Line; Etoposide; Humans; Lymphocytes; Melphalan; Methionine Sulfoximine; Verapamil | 1989 |
Enhancement of the anti-tumor effect of melphalan in experimental mice by some vaso-active agents.
Topics: Animals; Drug Synergism; Drug Therapy, Combination; Hydralazine; Melphalan; Mice; Neoplasms, Experimental; Nifedipine; Vasodilator Agents; Verapamil | 1989 |
In vitro studies of ways to overcome resistance to VAMP--high dose melphalan in the treatment of multiple myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cell Survival; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Melphalan; Methylprednisolone; Multiple Myeloma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil; Vincristine | 1989 |
Effects of verapamil and alcohol on blood flow, melphalan uptake and cytotoxicity, in murine fibrosarcomas and human melanoma xenografts.
Topics: Animals; Cinnarizine; Drug Synergism; Ethanol; Female; Fibrosarcoma; Flunarizine; Humans; Male; Melanoma; Melphalan; Mice; Mice, Inbred CBA; Regional Blood Flow; Verapamil | 1986 |
Pharmacologic reversal of drug resistance in ovarian cancer.
Topics: Antineoplastic Agents; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Glutathione; Humans; Hypertonic Solutions; Melphalan; Ovarian Neoplasms; Tumor Stem Cell Assay; Verapamil | 1985 |
Verapamil potentiation of melphalan cytotoxicity and cellular uptake in murine fibrosarcoma and bone marrow.
Topics: Animals; Bone Marrow; Cell Survival; Colony-Forming Units Assay; Drug Synergism; Female; Fibrosarcoma; Humans; Hydrolysis; In Vitro Techniques; Jejunum; Kinetics; Male; Melphalan; Mice; Mice, Inbred CBA; Verapamil | 1985 |
The effect of hyperthermia and verapamil on melphalan cytotoxicity and transport in multidrug-resistant Chinese hamster ovary cells.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Drug Resistance, Multiple; Drug Synergism; Hyperthermia, Induced; Melphalan; Verapamil | 1995 |
Modulation of melphalan and cisplatin cytotoxicity in human ovarian cancer cells resistant to alkylating drugs.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Blotting, Northern; Calcium Channel Blockers; Cell Survival; Cisplatin; Culture Media; Cystadenoma; Drug Resistance, Neoplasm; Female; Flunarizine; Humans; Melphalan; Nimodipine; Ovarian Neoplasms; RNA Probes; RNA, Neoplasm; Tumor Cells, Cultured; Verapamil | 1997 |
Cytotoxic and antitumor activity of MEN 10710, a novel alkylating derivative of distamycin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Calcium Channel Blockers; Cell Survival; Distamycins; Humans; Leukemia L1210; Melphalan; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Stem Cells; Nitrogen Mustard Compounds; Organ Size; Tumor Cells, Cultured; Verapamil | 1997 |
[The influence of verapamil on platelet function in patients with multiple myeloma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Doxorubicin; Female; Humans; Male; Melphalan; Middle Aged; Multiple Myeloma; Platelet Aggregation; Platelet Aggregation Inhibitors; Prednisone; Verapamil; Vincristine | 1997 |
A bioreversible prodrug approach designed to shift mechanism of brain uptake for amino-acid-containing anticancer agents.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Blood-Brain Barrier; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Drug Carriers; In Vitro Techniques; Isoxazoles; Male; Melphalan; Perfusion; Prodrugs; Radioactive Tracers; Rats; Rats, Sprague-Dawley; Verapamil | 2001 |
By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bcl-2-Like Protein 11; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Dasatinib; Dexamethasone; Down-Regulation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Melphalan; Membrane Proteins; Multiple Myeloma; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyrimidines; src-Family Kinases; Survivin; Thiazoles; Up-Regulation; Verapamil | 2014 |
Correlation of Technical and Adjunctive Factors with Quantitative Tumor Reduction in Children Undergoing Selective Ophthalmic Artery Infusion Chemotherapy for Retinoblastoma.
Topics: Antineoplastic Agents, Alkylating; Child; Child, Preschool; Cohort Studies; Female; Fluoroscopy; Humans; Infant; Infusions, Intra-Arterial; Male; Melphalan; Ophthalmic Artery; Retinal Neoplasms; Retinoblastoma; Retrospective Studies; Treatment Outcome; Vasodilator Agents; Verapamil | 2021 |