Compounds > verapamil

verapamil and mefloquine

verapamil has been researched along with mefloquine in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.56)	18.7374
1990's	8 (44.44)	18.2507
2000's	4 (22.22)	29.6817
2010's	4 (22.22)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kumari, D; Perveen, S; Sharma, R; Singh, K	1
Barnes, DA; Cowman, AF; Foote, SJ; Galatis, D; Kemp, DJ	1
Peters, W; Robinson, BL	1
Brockelman, CR; Bunnag, D; Satayavivad, J; Tan-ariya, P; Wongsawatkul, O	1
Holfels, E; Mack, D; McAuley, J; McLeod, R; Milhous, WK	1
Cowman, AF; Galatis, D; Lim, AS	1
Chung, R; Cowman, AF; Foley, M; Riffkin, CD; Tilley, L; Wall, DM; Zalcberg, JR	1
Bray, PG; Green, JE; Hawley, SR; Mungthin, M; Ritchie, GY; Ward, SA	1
Ayesh, S; Shao, YM; Stein, WD	1
Bray, PG; Mungthin, M; Ward, SA	1
Caruana, SR; Cowman, AF; Kirk, K; Reed, MB; Saliba, KJ	1
Fujita, R; Ishikawa, M; Sasaki, K; Takayanagi, M; Takayanagi, Y	1
Fidock, DA; Sidhu, AB; Verdier-Pinard, D	1
Ciach, M; Crandall, I; Kain, KC; Zong, K	1
Gbotosho, GO; Happi, CT; Lawal, O; Oduola, A; Sijuade, A; Sowunmi, A	1
Choi, AR; Kim, JH; Kim, YK; Yoon, S	1

Reviews

2 review(s) available for verapamil and mefloquine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance. European journal of medicinal chemistry, 2022, Feb-05, Volume: 229 Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mycobacterium tuberculosis; Nitroimidazoles; Oxazoles; Pyrazinamide; Rifampin	2022

Other Studies

16 other study(ies) available for verapamil and mefloquine

Article	Year
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5 Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine	2012
Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. The EMBO journal, 1992, Volume: 11, Issue:8 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Deletion; Chromosome Mapping; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Mefloquine; Membrane Glycoproteins; Plasmodium falciparum; Restriction Mapping; Verapamil	1992
The chemotherapy of rodent malaria. XLVI. Reversal of mefloquine resistance in rodent Plasmodium. Annals of tropical medicine and parasitology, 1991, Volume: 85, Issue:1 Topics: Animals; Antimalarials; Cyproheptadine; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Malaria; Mefloquine; Mice; Penfluridol; Plasmodium falciparum; Verapamil	1991
Flunarizine and verapamil inhibit chloroquine-resistant Plasmodium falciparum growth in vitro. The Southeast Asian journal of tropical medicine and public health, 1987, Volume: 18, Issue:2 Topics: Animals; Antimalarials; Chloroquine; Chlorpromazine; Drug Resistance; Flunarizine; Mefloquine; Plasmodium falciparum; Quinine; Quinolines; Regression Analysis; Verapamil	1987
In vitro effects of artemisinin ether, cycloguanil hydrochloride (alone and in combination with sulfadiazine), quinine sulfate, mefloquine, primaquine phosphate, trifluoperazine hydrochloride, and verapamil on Toxoplasma gondii. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:6 Topics: Animals; Artemisinins; Female; Mefloquine; Mice; Primaquine; Proguanil; Quinine; Sesquiterpenes; Sulfadiazine; Toxoplasma; Triazines; Trifluoperazine; Uracil; Verapamil	1994
Plasmodium falciparum: amplification and overexpression of pfmdr1 is not necessary for increased mefloquine resistance. Experimental parasitology, 1996, Volume: 83, Issue:3 Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; DNA, Protozoan; Drug Resistance, Multiple; Gene Amplification; Gene Dosage; Gene Expression Regulation; Genes, Protozoan; Mefloquine; Plasmodium falciparum; Protozoan Proteins; Sequence Analysis, DNA; Verapamil	1996
Modulation of the function of human MDR1 P-glycoprotein by the antimalarial drug mefloquine. Biochemical pharmacology, 1996, Nov-22, Volume: 52, Issue:10 Topics: Affinity Labels; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Biological Transport, Active; Chloroquine; Drug Interactions; Drug Resistance, Multiple; Fluorescent Dyes; Humans; Kinetics; Mefloquine; Neoplasms; Prazosin; Tumor Cells, Cultured; Verapamil; Vinblastine	1996
In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1. Molecular and biochemical parasitology, 1996, Dec-02, Volume: 83, Issue:1 Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Biological Transport; Chloroquine; DNA Fingerprinting; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Gene Dosage; Gene Expression; Immunoblotting; Mefloquine; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Selection, Genetic; Sequence Analysis, DNA; Verapamil	1996
Mutually co-operative interactions between modulators of P-glycoprotein. Biochimica et biophysica acta, 1997, Feb-27, Volume: 1360, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Drug Resistance, Multiple; Drug Synergism; Kinetics; Leukemia P388; Mefloquine; Tamoxifen; Tumor Cells, Cultured; Verapamil; Vinblastine	1997
Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:3 Topics: Animals; Antimalarials; Blotting, Western; Chloroquine; DNA Fingerprinting; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Gene Dosage; Genotype; Humans; Malaria, Falciparum; Mefloquine; Penfluridol; Phenanthrenes; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Quinine; Thailand; Verapamil	1999
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature, 2000, Feb-24, Volume: 403, Issue:6772 Topics: Amino Acid Substitution; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Mefloquine; Mutation; Phenanthrenes; Plasmodium falciparum; Protozoan Proteins; Quinine; Sesquiterpenes; Verapamil	2000
Enhancement of doxorubicin activity in multidrug-resistant cells by mefloquine. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:5 Topics: Affinity Labels; Antibiotics, Antineoplastic; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Calcium Channel Blockers; Coloring Agents; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mefloquine; Phenotype; Rhodamine 123; Tumor Cells, Cultured; Verapamil	2000
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations. Science (New York, N.Y.), 2002, Oct-04, Volume: 298, Issue:5591 Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil	2002
Reversal of mefloquine and quinine resistance in Plasmodium falciparum with NP30. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:8 Topics: Animals; Antimalarials; Calcium Channel Blockers; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Quinine; Surface-Active Agents; Verapamil	2003
A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans. Malaria journal, 2012, Feb-27, Volume: 11 Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Black People; Chromatography, High Pressure Liquid; Drug Combinations; Drug Monitoring; Humans; Mefloquine; Reference Standards; Reproducibility of Results; Saliva; Sensitivity and Specificity; Verapamil	2012
Co-treatment with the anti-malarial drugs mefloquine and primaquine highly sensitizes drug-resistant cancer cells by increasing P-gp inhibition. Biochemical and biophysical research communications, 2013, Nov-22, Volume: 441, Issue:3 Topics: Antimalarials; Antineoplastic Agents; Apoptosis; Artemisinins; Artesunate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chloroquine; Doxycycline; Drug Resistance, Neoplasm; Humans; Mefloquine; Primaquine; Verapamil; Vinblastine	2013