verapamil has been researched along with ly335979 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 8 (61.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castanys, S; Chávez Orellana, H; Estévez-Braun, A; Gamarro, F; Jiménez-Alonso, S; López, M; Muñoz Martinez, F; Pérez-Lomas, AL; Ravelo, AG | 1 |
| Chiba, P; Ecker, GF; Jabeen, I; Pleban, K; Rinner, U | 1 |
| Waghray, D; Zhang, Q | 1 |
| Abel, B; Ambudkar, SV; Barbuti, AM; Chen, ZS; Patel, BA; Talele, TT; Velagapudi, UK | 1 |
| Dash, AK; Dhulap, A; Haider, S; Kumar, D; Mukherjee, D | 1 |
| Baughman, TM; Bell, MG; Cao, J; Dantzig, AH; Ehlhardt, WJ; Elmquist, WF; Gruber, J; Kroin, JS; Law, KL; Norman, BH; Shepard, RL; Shih, C; Starling, JJ; Winter, MA | 1 |
| Covey, DF; Luker, GD; Nilsson, KR; Piwnica-Worms, D | 1 |
| Blom-Roosemalen, MC; Breimer, DD; de Boer, AG; Nabulsi, L; van der Sandt, IC; Voorwinden, HH; Vos, CM | 1 |
| Borchard, G; de Boer, AG; Deryckere, K; Florea, BI; Junginger, HE; Kooiman, K; Schrier, SM; van der Sandt, IC | 1 |
| Fang, W; Feng, Y; Hu, Y; Huang, W; Kodithuwakku, ND; Li, Y; Zhang, Y | 1 |
| Bleier, BS; Feldman, R; Han, X; Kocharyan, A; Singleton, A | 1 |
| Abel, B; Ambudkar, SV; Chufan, EE; Shukla, S | 1 |
| Ambudkar, SV; Lusvarghi, S | 1 |
1 review(s) available for verapamil and ly335979
| Article | Year |
|---|---|
Inhibit or Evade Multidrug Resistance P-Glycoprotein in Cancer Treatment.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Neoplasm; Humans; Protein Conformation | 2018 |
12 other study(ies) available for verapamil and ly335979
| Article | Year |
|---|---|
Bis-pyranobenzoquinones as a new family of reversal agents of the multidrug resistance phenotype mediated by P-glycoprotein in mammalian cells and the protozoan parasite Leishmania.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoquinones; Crystallography, X-Ray; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Leishmania tropica; Mice; Models, Molecular; Molecular Structure; NIH 3T3 Cells; Parasitic Sensitivity Tests; Phenotype; Stereoisomerism; Structure-Activity Relationship | 2008 |
Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzophenones; Binding Sites; Cell Line, Tumor; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Ligands; Models, Molecular; Molecular Conformation; Propafenone; Quantitative Structure-Activity Relationship; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2012 |
Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein.
Topics: Adenosine Triphosphatases; Amino Acids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Chemistry Techniques, Synthetic; Humans; Molecular Docking Simulation; Peptidomimetics; Protein Conformation; Structure-Activity Relationship; Thiazoles | 2018 |
Green chemistry appended synthesis, metabolic stability and pharmacokinetic assessment of medicinally important chromene dihydropyrimidinones.
Topics: Benzopyrans; Biochemical Phenomena; Green Chemistry Technology; Humans | 2019 |
Pharmacological characterization of LY335979: a potent cyclopropyldibenzosuberane modulator of P-glycoprotein.
Topics: Acridines; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dibenzocycloheptenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Isoquinolines; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Quinidine; Quinolines; Structure-Activity Relationship; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1997 |
Multidrug resistance (MDR1) P-glycoprotein enhances esterification of plasma membrane cholesterol.
Topics: 3T3 Cells; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Cholesterol; Cyclosporins; Dehydroepiandrosterone; Dibenzocycloheptenes; Drug Resistance, Multiple; Esterification; Humans; Isoquinolines; Mice; Progesterone; Quinolines; Stereoisomerism; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil | 1999 |
Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.
Topics: Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Blood-Brain Barrier; Caco-2 Cells; Carbamates; Cattle; Cell Line, Transformed; Cells, Cultured; Coculture Techniques; Cyclosporins; Dibenzocycloheptenes; Endothelium, Vascular; Furans; HIV Protease Inhibitors; Humans; Indinavir; LLC-PK1 Cells; Multidrug Resistance-Associated Proteins; Probenecid; Quinolines; Rats; Rats, Wistar; Ritonavir; Sulfonamides; Swine; Verapamil | 2001 |
Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3).
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Bronchi; Cell Line; Cell Polarity; Cell Survival; Cyclosporins; Deoxyglucose; Dibenzocycloheptenes; Epithelial Cells; Fluocinolone Acetonide; Humans; Immunoblotting; Mass Spectrometry; Microscopy, Confocal; Quinolines; Sodium Azide; Temperature; Time Factors; Trachea; Verapamil | 2001 |
The inhibitory and combinative mechanism of HZ08 with P-glycoprotein expressed on the membrane of Caco-2 cell line.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Caco-2 Cells; Cell Membrane; Chromatography, Liquid; Dibenzocycloheptenes; Doxorubicin; Drug Resistance, Multiple; Humans; Isoquinolines; Mass Spectrometry; Microscopy, Fluorescence; Quinolines; Rhodamine 123; RNA, Small Interfering; Verapamil | 2014 |
P-glycoprotein inhibition promotes prednisone retention in human sinonasal polyp explants.
Topics: Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytoplasm; Dibenzocycloheptenes; Humans; Nasal Polyps; Prednisone; Quinolines; Verapamil | 2014 |
Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions.
Topics: Acridines; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Baculoviridae; Binding Sites; Detergents; Dibenzocycloheptenes; Drug Delivery Systems; Drug Evaluation, Preclinical; Glucosides; Humans; Hydrolysis; Inhibitory Concentration 50; Insecta; Ligands; Mice; Micelles; Peptides, Cyclic; Protein Binding; Quinolines; Tetrahydroisoquinolines; Verapamil | 2017 |
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators.
Topics: Acridines; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; Calcium Channel Blockers; Cell Line; Dibenzocycloheptenes; Gene Expression Regulation; Humans; Insecta; Protein Binding; Protein Conformation; Protein Stability; Quinolines; Temperature; Tetrahydroisoquinolines; Verapamil | 2019 |