verapamil has been researched along with lidocaine in 297 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 151 (50.84) | 18.7374 |
| 1990's | 68 (22.90) | 18.2507 |
| 2000's | 41 (13.80) | 29.6817 |
| 2010's | 33 (11.11) | 24.3611 |
| 2020's | 4 (1.35) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Dubinsky, B; Moore, JB; Press, JB; Sanfilippo, PJ; Urbanski, M | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Caron, G; Ermondi, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Bajda, M; Brus, B; Czerwińska, P; Filipek, B; Gobec, S; Malawska, B; Sałat, K; Więckowska, A; Więckowski, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bienkowski, P; Bucki, A; Gobec, S; Godyń, J; Głuch-Lutwin, M; Kazek, G; Knez, D; Kołaczkowski, M; Malawska, B; Marcinkowska, M; Mierzejewski, P; Sienkiewicz-Jarosz, H; Siwek, A; Wichur, T; Więckowska, A; Więckowski, K; Zaręba, P | 1 |
| Brazzolotto, X; Brus, B; Colletier, JP; Coquelle, N; Gobec, S; Knez, D; Kos, J; Košak, U; Nachon, F; Pišlar, A | 1 |
| Cai, G; Cai, J; Calcul, L; Cheng, F; Jia, R; Li, C; Li, Q; Luo, X; She, F; Sun, X; Wang, D; Wang, S; Wang, Y; Wei, L; Yu, J; Zheng, M; Zhou, M | 1 |
| Julian, DG | 2 |
| Jewitt, DE | 1 |
| Curione, M; Puletti, M | 1 |
| Theisen, K | 1 |
| Klein, W | 1 |
| Coumel, P; Krikler, D; Rosen, MR; Wellens, HJ; Zipes, DP | 1 |
| Basiez, M; Labrid, C; Leinot, M; Talvard, J | 1 |
| Papadimituiou, JM; Sforcina, D | 1 |
| Doshchitsin, VL | 1 |
| Bender, F | 2 |
| Merx, W | 1 |
| Gettes, LS | 2 |
| Csapo, G | 1 |
| Federman, J; Vlietstra, RE | 1 |
| Bacca, F; Bray, A; Calabrese, G; De Giorgi, V; Lombardi, R; Montinaro, A; Spirito, F | 1 |
| Blitstein-Willinger, E; Diamantstein, T; Lother, H | 1 |
| Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA | 1 |
| Doshchitsin, VL; Fedorova, IF; Gendlin, GE; Pozin, VM; Skuratovskaia, SG | 1 |
| Imanishi, S; McAllister, RG; Surawicz, B | 1 |
| McCall, D | 1 |
| Doenecke, VP | 1 |
| von Knorre, GH | 1 |
| Doenecke, P | 1 |
| Narimatsu, A; Taira, N | 1 |
| Wellens, HJ | 1 |
| Araú, A; Bonhorst, D; Bordalo, A; De Azevedo, JG; Ferreira, M; Ferreira, R; Inês, L; Lacximy, I; Longo, A; Luis Martins, J; Melo, M; Nunes Diogo, A; Ribeiro, C; Sanches, C; Teixeira, J | 1 |
| Kohlhardt, M | 1 |
| Steinbach, K | 1 |
| Arnsdorf, MF | 1 |
| Bake, I; Buttazzoni, E; Csongrady, A; Pfänder, C; Schneider, M; Tarmann, H | 1 |
| Liu, WY; Zheng, LR; Zhou, JT | 1 |
| Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y; Yamazaki, M | 1 |
| Galkowska, H; Olszewski, WL | 2 |
| Ji, GJ; Liu, DQ; Sheng, BH; Zhao, DH | 2 |
| Boachie-Ansah, G; Kane, KA; Pacini, DJ | 1 |
| Raberger, G; Todt, H | 1 |
| Abete, P; Balbi, R; Caccese, P; Ferrara, N; Landino, P; Leosco, D; Rengo, F; Sederino, S | 1 |
| Li, C; Liu, TF; Zeng, YM; Zhuang, CX | 1 |
| Gorgels, AP; Havenith, MG; Kriek, E; Leunissen, JD; Smeets, JL; Vos, MA; Wellens, HJ | 1 |
| Brown, JE; Guiraudon, GM; Jones, DL; Klein, GJ; Sharma, AD; Yee, R | 1 |
| Sugano, S; Suzuki, J; Tsubone, H | 1 |
| Rubin, E; Stewart, G; Thomas, AP | 1 |
| Belpaire, FM; Bogaert, MG; Bourda, A; De Rick, A; De Smet, F; Rosseel, MT | 2 |
| Andries, LJ; Boels, PJ; Brutsaert, DL; De Laey, JJ; Hoste, AM | 1 |
| Bingmann, D; Hagemann, G; Lipinski, HG; Speckmann, EJ; Tetsch, P | 1 |
| Huang, J | 1 |
| Akiyama, K; Hashimoto, K | 1 |
| Dankó, M; Lathrop, DA; Nánási, PP; Varró, A | 1 |
| Hunter, JB; Pegram, BL; Peters, T; Scheufler, E; Vogelgesang, R; Wermelskirchen, D; Wilffert, B | 1 |
| Elliott, P | 1 |
| Peters, T; Scheufler, E | 1 |
| Lantos, J; Sárosi, I; Temes, G; Török, B | 1 |
| Keefe, DL; Miura, D; Somberg, JC | 1 |
| Adamantidis, MM; Caron, JF; Dupuis, BA | 1 |
| Lucchesi, BR; Lynch, JJ | 1 |
| Enyeart, JJ; Hinkle, PM; Phillips, WJ | 1 |
| Mehmel, HC | 1 |
| Ageel, AM; al-Obeid, HA; al-Rashood, KA; el Tahir, KE; Madani, AA | 1 |
| Angel, MF; Mahoney, JE; Mitchell, GM; Morrison, WA; O'Brien, BM; Pederson, WC; Singer, DI | 1 |
| Antman, EM; Smith, TW | 1 |
| Somberg, J | 1 |
| Arzbaecher, R; Bump, TE; Guezennec, A; Ripley, KL | 1 |
| Andersson, KE; Wettrell, G | 1 |
| Morganroth, J; Nestico, PF | 1 |
| Huang, SK; Marcus, FI | 1 |
| Fournier, DJ; Grogan, DL; Kapur, PA | 1 |
| Rosenblatt, RM; Tallman, RD; Wang, YL; Weaver, JM | 1 |
| Bálint, Z; Szekeres, L; Tósaki, A | 1 |
| Gülker, H; Haverkamp, W; Hindricks, G; Thale, J | 1 |
| Dill, PL; Duarte, TE; Nagourney, RA; Su, YZ; Weisenthal, LM | 1 |
| Barbalonga, A; Cesano, L; Pallisco, O; Vietti Ramus, G | 1 |
| Ahn, HY; Karaki, H; Urakawa, N | 1 |
| Bitto, U; Casella, G; Freni, F; Mazzù, A | 1 |
| Goto, Y; Kanemoto, N; Satoh, M; Tagawa, R | 1 |
| Abernethy, DR; Chelly, JE; Dlewati, A; Doursout, MF; Hill, DC; Merin, RG | 1 |
| Eguchi, K; Kamiyama, A; Shibayama, R | 1 |
| Schwartz, PJ; Vanoli, E | 1 |
| Littmann, L; Tenczer, J | 1 |
| Kinnaird, AA; Man, RY | 3 |
| Kano, T; Nishi, K | 1 |
| Carpenter, RL; Mulroy, MF | 1 |
| Balla, S; Hariman, RJ; Punatar, HK; Shenoy, MM | 1 |
| Arena, JP; Laxminarayan, S; McArdle, JJ | 1 |
| Hirosawa, K; Kasanuki, H; Onishi, S | 1 |
| Agmon, J; Arditti, A; Kusniec, J; Lewin, RF; Sclarovsky, S; Strasberg, B | 1 |
| Karagueuzian, HS; Mandel, WJ; Ohta, M; Peter, T; Sugi, K | 1 |
| Grover, JK; Kothekar, V; Reddy, G; Tiku, P | 1 |
| Hashimoto, K; Imai, S; Shibuya, T | 1 |
| Abernethy, DR; Schwartz, JB; Todd, EL | 1 |
| Hoffman, BF; Legenza, M; Southworth, SR; Temesy-Armos, PN | 1 |
| Riccioppo Neto, FR; Sperelakis, N | 1 |
| Diedrich, R; Hardewig, A | 1 |
| Kaufmann, G | 1 |
| Clodi, PH; Hartl, O | 1 |
| Chatillon, J | 1 |
| Hauswirth, O; Singh, BN | 1 |
| Heeg, E; Reuter, N; Steiger, H | 1 |
| Strubelt, O; Zetler, G | 1 |
| Bleifeld, W; Effert, S; Merx, W | 1 |
| Collignon, P; Kulbertus, H | 1 |
| Bauer, B; Fleckenstein, A; Kohlhardt, M; Krause, H | 1 |
| Filias, N | 1 |
| Boissier, JR; Giudicelli, JF; Larno, S; Witchitz, S | 1 |
| Södermark, T; Winge, T | 1 |
| Bender, F; Bräuer, B; Brisse, B; Müller, W | 1 |
| Reuter, N | 1 |
| Awa, S; Linde, LM; Turner, SW | 1 |
| Schollmeyer, P | 1 |
| Büchner, M; Effert, S; Grosse-Brockhoff, F | 1 |
| Opie, LH | 1 |
| Karagueuzian, HS; Katzung, BG | 1 |
| Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P | 1 |
| Elkayam, U; Frishman, W; Rotmensch, HH | 1 |
| Hillis, WS; Whiting, B | 1 |
| Prystowsky, EN | 1 |
| Somberg, JC | 1 |
| Jahrmärker, H; Theisen, K | 1 |
| Duff, HJ; Oates, JA; Roden, DM; Woosley, RL | 1 |
| Mohiuddin, SM; Ross, WB | 1 |
| Beinart, C; Saddekni, S; Sniderman, KW; Sos, TA; Weiner, MA | 1 |
| Ehlert, FJ; Fairhurst, AS; Whittaker, ML | 1 |
| Kawamuro, A; Matsuoka, A; Takashima, S | 1 |
| Motté, G | 1 |
| Arita, M; Kiyosue, T | 1 |
| Szekeres, L | 1 |
| Aomine, M; Arita, M; Imanishi, S; Kiyosue, T | 1 |
| Hay, DW; Wadsworth, RM | 1 |
| Bhatia, ML; Kaul, U; Mohan, JC | 1 |
| Sanguinetti, MC; West, TC | 1 |
| Hess, DS; Scheinman, MM | 1 |
| Bussmann, WD; Grüngras, M; Seher, W | 1 |
| Rosen, MR; Wit, AL | 1 |
| Atarashi, H; Elharrar, V; Surawicz, B | 1 |
| Anno, T; Furuta, T; Itoh, M; Kodama, I; Toyama, J; Yamada, K | 1 |
| Alps, BJ; Calder, C; Wilson, A | 1 |
| Gilmour, RF; Takahashi, N; Zipes, DP | 1 |
| Nademanee, K; Singh, BN | 1 |
| Sekeresh, L | 1 |
| Hirosawa, K; Kasanuki, H; Ohnishi, S | 1 |
| Hashimoto, K; Imai, S; Satoh, H; Shibuya, T | 2 |
| McGowan, FX; Pritchett, EL; Reiter, MJ; Shand, DG | 1 |
| Bertrix, L; Bouzouita, K; Chah, QT; Faucon, G; Lang, J | 1 |
| Finley, CD; Lin, FC; Rahimtoola, SH; Wu, D | 1 |
| Hatano, M; Ozawa, Y; Saito, S; Takahashi, N; Tanigawa, N; Watanabe, I | 1 |
| Zeng, GY | 1 |
| Alperovich, G; Jalife, J; Megna, JL; Salata, JJ | 1 |
| Dreifus, LS; Morganroth, J | 1 |
| Lukoshevichiute, AI; Reĭngardene, DI | 1 |
| Abbott, JA | 1 |
| Danilo, P; Ilvento, JP; Provet, J; Rosen, MR | 1 |
| Davis, J; Glassman, R; Wit, AL | 1 |
| De Cosmo, G; Foti, A; Proietti, R; Sabato, AF | 1 |
| Eichelbaum, M; Gugler, R; Somogyi, A | 1 |
| Gintautas, J; Havasi, G; Kiran, B; Kraynack, BJ | 1 |
| Hattori, Y; Kanno, M; Nakaya, H | 1 |
| Bergey, JL; McCallum, JD; Nocella, K | 1 |
| Takahashi, N | 1 |
| Hasin, Y; Rogel, S; Sarel, O | 1 |
| Hung, JS; Kou, HC; Wu, D | 1 |
| Campbell, RW | 1 |
| Danilo, P; Rosen, MR | 1 |
| Danilo, P; Hordof, AJ; Malm, JR; Mary-Rabine, L; Rosen, MR | 1 |
| Dreifus, LS; Kaplinsky, E; Kmetzo, JJ; Michelson, EL; Naito, M | 1 |
| Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C | 1 |
| Haruno, A; Hashimoto, K | 1 |
| Buffington, CW; Strum, DP; Watanabe, S | 1 |
| Prostran, M; Todorović, Z; Varagić, VM | 1 |
| Ferrier, GR; Howlett, SE | 1 |
| Imanishi, S; Miyamae, S | 1 |
| Cook, DI; Ishikawa, T | 1 |
| De Clerck, F; Lu, HR | 1 |
| French, RJ; Zamponi, GW | 1 |
| Igbo, IN; Onuaguluchi, G | 1 |
| Iwasaki, H; Kawamata, M; Namiki, A; Omote, K; Satoh, O | 1 |
| Bu, X; Jiang, MZ; Li, ST; Wen, Y; Zhang, ZH | 1 |
| Kupersmith, J; Li, ZY; Maldonado, C; Wang, YH | 1 |
| Hayashi, Y; Kamibayashi, T; Kawabata, K; Sumikawa, K; Takada, K; Yamatodani, A; Yoshiya, I | 1 |
| Cronenberger, CL; Griffith, RK; Lalka, D | 1 |
| Fu, L; Ishibashi, H; Kato, K; Namiki, T; Sagara, K; Sekiguchi, A | 1 |
| De Clerck, F; Lu, HR; Remeysen, P | 1 |
| Eichler, HG; Kastner, J; Krejcy, K; Schmetterer, L; Unfried, C; Wolzt, M; Zanaschka, G | 1 |
| Guttmann, I; Mozes, A; Scheufler, E; Wilffert, B | 1 |
| Iwasa, A; Okumura, K; Tabuchi, T; Tsuchiya, T; Yamabe, H; Yasue, H | 1 |
| Aizawa, Y; Mitamura, H; Miyazaki, T; Miyoshi, S; Ogawa, S; Soejima, K | 1 |
| Nakata, Y; Nakazato, K; Nakazato, Y; Ogura, S; Sumiyoshi, M; Tokano, T; Yamagami, S; Yamaguchi, H; Yasuda, M | 1 |
| Benson, DW; Hughes, SF; Lahoti, A; Naheed, ZJ | 1 |
| Honda, N; Miyagawa, A; Mizutani, A; Oyama, T; Taniguchi, K | 1 |
| Roder, JD; Sangiah, S; Shen, Y | 1 |
| Coopersmith, C; Erskine, MS; Gans, SE; Rowe, DW | 1 |
| Attolini, L; Bruguerolle, B; Gantenbein, M; Grignon, S; Jacob, D | 1 |
| Adgey, AA; Allen, JD; Devine, AB; Stewart, AJ | 1 |
| Fraudeau, C; Luck, G; Mangani, F; Vérette, E | 1 |
| Casanova, JM; De Micheli, A; Iturralde, P; Medrano, GA | 1 |
| Bannenberg, GL; Gustafsson, LE | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H; Shiga, M; Takao, Y | 1 |
| Jacobsen, EA; Mortensen, E; Pedersen, HK; Refsum, H | 1 |
| Ferrier, GR; Howlett, SE; Zhu, JQ | 1 |
| Ellenbogen, KA; Gilligan, DM; Natale, A; Shepard, RK; Stambler, BS; Wood, MA | 1 |
| Grant, C; Gray, E; Huang, YF; Upton, RN; Zheng, D | 1 |
| De Smet, P; Li, J; Van Driessche, W | 1 |
| Bartashevich, VV; Boldin, VB; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI; Popov, PB; Sirotenko, DV; Uvarov, AV | 1 |
| Dai, DZ; De Clerck, F; Lu, HR; Remeysen, P; Saels, A; Yang, P | 1 |
| Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M; Yamauchi, S | 1 |
| Clauss, W; Heinke, B | 1 |
| Orszulak-Michalak, D; Owczarek, J; Wiktorowska, A | 1 |
| Hagihara, A; Hashimoto, K; Sugiyama, A | 1 |
| Buncke, HJ; Chen, SG; Dogan, T; Komorowska-Timek, E; Lineaweaver, WC; Zhang, F | 1 |
| Daha, K; Engelhardt, P; Pflüger, H; Plas, E; Riedl, CR | 1 |
| Freitas-da-Fonseca, A; Mårdh, PA; Martinez-de-Oliveira, J; Pina-Vaz, C; Rodrigues, AA | 1 |
| Abe, S; Akatsu, M; Endoh, N; Kikuchi, Y; Meguro, T; Mitsuoka, M; Takizawa, K; Terashima, M | 1 |
| Bosnjak, ZJ; Contney, S; Kulier, AH; Lathrop, DA; Turner, LA; Vodanovic, S | 1 |
| Reuben, JP; Reuben, SS | 1 |
| Halawa, B | 1 |
| Cardinal, R; Lemarbre, F; Vermeulen, M; Vinet, A | 1 |
| Ashikaga, K; Honda, T; Iwasa, A; Okumura, K; Tsuchiya, T | 1 |
| Krüger, T; Lebek, S; Reichel, H; Wohlrab, D | 1 |
| Cengiz, P; Shah, M | 1 |
| Chi, CS; Fu, YC; Jan, SL; Wang, JD | 1 |
| Jankovic, SM; Jankovic, SV; Protic, BA | 1 |
| Hein, W; Klapperstück, T; Vocke, M; Wohlrab, D | 1 |
| Aihara, N; Kamakura, S; Kurita, T; Nagai, T; Noda, T; Satomi, K; Shimizu, W; Suyama, K | 1 |
| Juvekar, AR; Shah, KJ | 1 |
| Humeau, Y; Lüthi, A | 1 |
| Arakaki, T; Isomoto, S; Kawakami, A; Ono, K; Yamashita, S; Yano, K | 1 |
| Chu, CS; Lai, WT; Lee, KT; Lin, TH; Sheu, SH; Voon, WC; Yen, HW | 1 |
| Cohen, AS; Goadsby, PJ | 1 |
| Harada, M; Honjo, H; Ishiguro, YS; Kamiya, K; Kodama, I; Morishima, M; Nakagawa, H; Okuno, Y; Opthof, T; Sakuma, I; Suzuki, T; Takanari, H; Yamazaki, M | 1 |
| Dosdall, DJ | 1 |
| Cockerham, YR; Hellstrom, WJ | 1 |
| Afrasiabi, MA; Ardeshiri, M; Karbalay-Doust, S; Monabati, A; Noorafshan, A; Shirazi, M | 1 |
| Morita, H; Morita, ST; Wu, J; Zipes, DP | 1 |
| Antoons, G; Attevelt, NJ; Beekman, JD; Belardinelli, L; Gomez, AM; Houtman, MJ; Neco, P; Oosterhoff, P; Oros, A; Rajamani, S; Richard, S; van der Heyden, MA; Ver Donck, L; Vos, MA | 1 |
| Imai, T; Kajimoto, K; Kasanuki, H; Minami, Y | 1 |
| Chiale, PA; Elizari, MV; Faivelis, L; Fernández, PA; Garro, HA; Herrera Paz, JJ | 1 |
| Ding, AW; Duan, JA; Lü, GH; Lu, WJ; Ma, HY; You, FQ; Zhou, J | 1 |
| Baranchuk, A; Chiale, PA; Elizari, MV; Femenía, F; Garro, HA | 1 |
| Perlík, F | 1 |
| Cocalis, M; Foltz, R; Hiremath, G; Li, W; Roy-Burman, A; Tanel, RE | 1 |
| Artmann, AT; Artmann, GM; Bayer, R; Epple, M; Frotscher, R; Goßmann, M; Linder, P; Neumann, S; Staat, M | 1 |
| Hosseini, M; Johannesen, L; Mason, JW; Pueyo, E; Sager, PT; Strauss, DG; Vicente, J | 1 |
| Ando, K; Cao, X; Izumi-Nakaseko, H; Matsukura, S; Nakamura, Y; Sugiyama, A; Wada, T; Yamazaki, H | 1 |
| Perry, MS; Turner, AL | 1 |
| Bergau, D; Bystricky, W; Carter, D; Gintant, G; Kamradt, K; Maier, C; Welsh, P | 1 |
| Dai, Y; Kim, ES; Lee, BK; Lee, DW; Oyunbaatar, NE; Shanmugasundaram, A | 1 |
| Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B | 1 |
| Jeong, YJ; Kim, ES; Lee, BK; Lee, DW; Oyunbaatar, NE; Shanmugasundaram, A | 1 |
| Burke, NS; Costa, AP; Court, MH; Mealey, KL; Villarino, NF | 1 |
| Guo, Y; Han, Y; Li, Y; Liang, X; Lu, Y; Sang, W; Tang, B; Wang, F; Wang, L; Xiaokereti, J; Xing, Q; Zhang, J; Zhang, L; Zhou, X; Zukela, T | 1 |
25 review(s) available for verapamil and lidocaine
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Cardiac arrhythmias - a short review.
Topics: Adrenergic beta-Agonists; Arrhythmias, Cardiac; Digitalis Glycosides; Electric Countershock; Electrocardiography; Humans; Lidocaine; Mexiletine; Pacemaker, Artificial; Phenytoin; Procainamide; Quinidine; Verapamil | 1976 |
Limitations of present drug therapy of cardiac arrhythmias--a review.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Humans; Lidocaine; Procainamide; Quinidine; Verapamil | 1977 |
The treatment of ventricular rhythm disturbances.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil | 1986 |
Digitalis toxicity.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Biological Availability; Carotid Sinus; Digitalis Glycosides; Drug Interactions; Electric Countershock; Heart; Heart Conduction System; Humans; Kinetics; Lidocaine; Parasympathetic Nervous System; Phenytoin; Potassium; Procainamide; Quinidine; Sympathetic Nervous System; Verapamil | 1985 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil | 1985 |
Cardiovascular drugs. I: Antidysrhythmic drugs.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Disopyramide; Drug Interactions; Humans; Kinetics; Lidocaine; Mexiletine; Phenytoin; Procainamide; Tocainide; Verapamil | 1986 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Antiarrhythmic drug therapy of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil | 1986 |
[Anti-arrhythmia agents].
Topics: Action Potentials; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Heart; Heart Conduction System; Humans; Lidocaine; Phenytoin; Practolol; Procainamide; Quinidine; Sparteine; Ventricular Fibrillation; Verapamil | 1974 |
Comparative mechanisms of action of antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil | 1974 |
Antiarrhythmic drug therapy during pregnancy.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis Glycosides; Disopyramide; Female; Fetus; Humans; Infant, Newborn; Lidocaine; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Tachycardia; Verapamil | 1983 |
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atrial Fibrillation; Benzofurans; Digitalis Glycosides; Disopyramide; Encainide; Female; Humans; Lidocaine; Male; Middle Aged; Procainamide; Quinidine; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Physiology and pharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Anti-Arrhythmia Agents; Cell Membrane; Heart Conduction System; Humans; Ion Channels; Kinetics; Lidocaine; Membrane Potentials; Myocardium; Quinidine; Verapamil | 1981 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil | 1983 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil | 1983 |
Antiarrhythmic agents and their use in therapy.
Topics: Acebutolol; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Humans; Lidocaine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1980 |
[Value of drug tests in Wolff-Parkinson-White syndrome].
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrioventricular Node; Diagnosis, Differential; Electrocardiography; Humans; Lidocaine; Myocardial Infarction; Procainamide; Quinidine; Verapamil; Wolff-Parkinson-White Syndrome | 1981 |
Intravenous antiarrhythmic drugs: newer aspects of therapy.
Topics: Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Hemodynamics; Humans; Injections, Intravenous; Lidocaine; Tachycardia; Verapamil | 1982 |
The hepatic first-pass metabolism of problematic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Humans; Lidocaine; Liver; Metabolic Clearance Rate; Models, Biological; Nitroglycerin; Pharmaceutical Preparations; Propafenone; Propranolol; Verapamil | 1993 |
[Pathophysiology and treatment of trigeminal autonomic cephalalgias].
Topics: Administration, Oral; Amines; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cluster Headache; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indomethacin; Lamotrigine; Lidocaine; Male; Methysergide; Nociceptors; Oxygen Inhalation Therapy; Paroxysmal Hemicrania; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; SUNCT Syndrome; Topiramate; Triazines; Trigeminal Autonomic Cephalalgias; Trigeminal Nerve; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2008 |
[Effect of liver cirrhosis on pharmacokinetics and pharmacodynamics of drugs].
Topics: Analgesics; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertensive Agents; Hepatic Insufficiency; Humans; Lidocaine; Liver; Liver Cirrhosis; Metoprolol; Propranolol; Risk; Verapamil | 2013 |
Outside the box: Medications worth considering when traditional antiepileptic drugs have failed.
Topics: Amantadine; Anticonvulsants; Bumetanide; Central Nervous System Stimulants; Epilepsy; Humans; Imipramine; Lidocaine; Treatment Failure; Verapamil | 2017 |
10 trial(s) available for verapamil and lidocaine
| Article | Year |
|---|---|
Selection of an antiarrhythmic drug for a sudden-death-prevention trial.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Moricizine; Morpholines; Phenothiazines; Piperidines; Tocainide; Verapamil | 1982 |
[Reduction in CK- and CKMB-measured infarct size by verapamil].
Topics: Blood Pressure; Creatine Kinase; Dose-Response Relationship, Drug; Furosemide; Heart Block; Heart Rate; Humans; Isoenzymes; Lidocaine; Myocardial Infarction; Nitroglycerin; Verapamil | 1983 |
Short-term drug effects on the signal-averaged electrocardiogram in healthy men: assessment of intra- and interindividual variability of spectral temporal mapping and time-domain analysis.
Topics: Adenosine; Adult; Atropine; Cardiovascular Agents; Cross-Over Studies; Electrocardiography; Heart; Hemodynamics; Humans; Isoproterenol; Lidocaine; Male; Norepinephrine; Placebos; Propranolol; Reference Values; Reproducibility of Results; Time Factors; Verapamil | 1995 |
The effect of calcium channel antagonist administered by iontophoresis on the pain threshold.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Drug Combinations; Female; Humans; Iontophoresis; Lidocaine; Male; Nicardipine; Pain; Sensory Thresholds; Time Factors; Verapamil | 1995 |
Attenuation of cardiovascular responses to tracheal extubation: comparison of verapamil, lidocaine, and verapamil-lidocaine combination.
Topics: Adult; Anesthetics, Local; Anti-Arrhythmia Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Intubation, Intratracheal; Lidocaine; Male; Tachycardia; Verapamil | 1997 |
Iontophoresis for treatment of Peyronie's disease.
Topics: Adult; Aged; Anti-Inflammatory Agents; Dexamethasone; Humans; Iontophoresis; Lidocaine; Male; Middle Aged; Penile Induration; Prospective Studies; Verapamil | 2000 |
Response of the radial artery to three vasodilatory agents.
Topics: Adult; Aged; Aged, 80 and over; Coronary Angiography; Female; Humans; Isosorbide Dinitrate; Lidocaine; Male; Middle Aged; Radial Artery; Vasodilation; Vasodilator Agents; Verapamil | 2000 |
Brachial plexus anesthesia with verapamil and/or morphine.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Anesthetics, Local; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Lidocaine; Male; Middle Aged; Morphine; Nerve Block; Orthopedics; Pain Measurement; Verapamil | 2000 |
Electrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current Block.
Topics: Adult; Biomarkers; Calcium Channel Blockers; Cross-Over Studies; Electrocardiography; Ether-A-Go-Go Potassium Channels; Female; Heart; Heart Rate; Humans; Lidocaine; Long QT Syndrome; Male; Mexiletine; Phenethylamines; Potassium Channel Blockers; Sodium; Sodium Channel Blockers; Sulfonamides; Torsades de Pointes; Verapamil | 2016 |
T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization.
Topics: Action Potentials; Adult; Databases, Factual; Double-Blind Method; Electrocardiography; Female; Heart; Humans; Lidocaine; Male; Mexiletine; Phenethylamines; Potassium Channel Blockers; Ranolazine; Sodium Channel Blockers; Sulfonamides; Verapamil; Young Adult | 2019 |
262 other study(ies) available for verapamil and lidocaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Synthesis of (aryloxy)alkylamines. 2. Novel imidazo-fused heterocycles with calcium channel blocking and local anesthetic activity.
Topics: Amines; Anesthetics, Local; Animals; Calcium Channel Blockers; Drug Evaluation, Preclinical; Heterocyclic Compounds; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Rabbits; Trachea | 1988 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
Topics: Acetylcholinesterase; Alzheimer Disease; Amnesia; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Disease Models, Animal; Donepezil; Humans; Indans; Indoles; Male; Memory; Mice; Models, Molecular; Neuroprotective Agents; Phthalimides; Piperidines; Protein Aggregates; Scopolamine; Structure-Activity Relationship | 2015 |
Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Catalytic Domain; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Ligands; Male; Models, Molecular; Molecular Targeted Therapy; Protein Conformation; Rats; Rats, Wistar; Receptors, Serotonin | 2016 |
N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Butyrylcholinesterase; Cell Death; Cell Line; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Naphthalenes; Peptide Fragments; Piperidines; Structure-Activity Relationship; Sulfonamides | 2017 |
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR.
Topics: Dose-Response Relationship, Drug; Drug Discovery; ErbB Receptors; Ligands; Molecular Structure; Peptidomimetics; Structure-Activity Relationship | 2021 |
[Drug therapy of pre-excitation syndromes].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Humans; Lidocaine; Quinidine; Syndrome; Tachycardia, Paroxysmal; Verapamil | 1977 |
[Drug therapy of tachyarrhythmias (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1978 |
[Drug therapy of tachycardial heart-rhythm disorders].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Humans; Lidocaine; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1976 |
Newer antiarrhythmic drugs.
Topics: Administration, Oral; Adult; Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Child; Edrophonium; Electrophysiology; Heart Conduction System; Heart Ventricles; Humans; Injections, Intravenous; Lidocaine; Mexiletine; Recurrence; Tachycardia; Tocainide; Verapamil; Wolff-Parkinson-White Syndrome | 1978 |
[Prolongation of the effective refractory period on isolated guinea pig atria by some anti-arrhythmia agents: relevance in a comparison of their potentialities].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Function; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Lidocaine; Myocardial Contraction; Nifedipine; Verapamil | 1979 |
The effects of drugs on monocytic fusion in vivo.
Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Fusion; Cell Membrane; Cortisone; Cyclic AMP; Diphenhydramine; Edetic Acid; Glucagon; Insulin; Isoproterenol; Lidocaine; Lysosomes; Male; Mice; Mice, Inbred C57BL; Monocytes; Ouabain; Pyrilamine; Tetracaine; Trifluoperazine; Verapamil | 1975 |
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil | 1975 |
[Letter: Paroxysmal supraventricular and ventricular tachycardia].
Topics: Adrenergic beta-Antagonists; Aprindine; Heart Ventricles; Humans; Lidocaine; Phenytoin; Quinidine; Tachycardia, Paroxysmal; Time Factors; Verapamil | 1975 |
[New aspects concerning drug therapy of arrhythmia].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Autonomic Nervous System; Bretylium Compounds; Humans; Lidocaine; Membrane Potentials; Parasympatholytics; Parasympathomimetics; Phenytoin; Procainamide; Quinidine; Verapamil | 1975 |
Modern concepts of cardiovascular disease.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrocardiography; Heart; Heart Conduction System; Humans; Lidocaine; Quinidine; Verapamil | 1979 |
Paroxysmal nonreentrant tachycardias due to simultaneous conduction in dual atrioventricular nodal pathways.
Topics: Adult; Ajmaline; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle of His; Cardiac Pacing, Artificial; Electrocardiography; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Metoprolol; Models, Biological; Tachycardia, Paroxysmal; Verapamil | 1979 |
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil | 1979 |
[Preventive effectiveness of verapamil in ventricular fibrillation in the first 24 hours after myocardial infarct].
Topics: Acute Disease; Adult; Aged; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Ventricular Fibrillation; Verapamil | 1979 |
Studies on the relevance of microtubules and of microfilament-dependent processes for triggering lymphocyte activation.
Topics: Animals; Cell Membrane; Cells, Cultured; Cytoplasm; Cytoskeleton; Immunologic Capping; Lidocaine; Lymphocyte Activation; Lymphocytes; Mice; Microtubules; Mitogens; Rabbits; Spleen; Verapamil | 1979 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1978 |
[Prevention of ventricular fibrillation in animal experiments].
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Drug Evaluation; Lidocaine; Pindolol; Rats; Ventricular Fibrillation; Verapamil | 1978 |
The effects of verapamil and lidocaine on the automatic depolarizations in guinea-pig ventricular myocardium.
Topics: Animals; Calcium; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Lidocaine; Membrane Potentials; Verapamil | 1978 |
Responses of cultured heart cells to procainamide and lignocaine.
Topics: Animals; Cells, Cultured; Heart; Lidocaine; Myocardial Contraction; Myocardium; Procainamide; Rats; Sodium; Verapamil | 1978 |
[Myocardial excitability under the influence of digitalis glycosides and anti-arrhythmia agent].
Topics: Ajmaline; Anti-Arrhythmia Agents; Digitalis Glycosides; Digoxin; Heart Conduction System; Humans; Lidocaine; Myocardial Contraction; Phenytoin; Procainamide; Propranolol; Refractory Period, Electrophysiological; Stimulation, Chemical; Verapamil | 1977 |
[Basic comments on the treatment of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Heart Block; Humans; Hypnotics and Sedatives; Lidocaine; Pacemaker, Artificial; Procainamide; Quinidine; Sparteine; Verapamil | 1977 |
[Influence of cardiac agents on the diastolic irritability of the ventricular myocardium. Consequences for pacemaker therapy].
Topics: Adult; Aged; Ajmaline; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Dogs; Female; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Contraction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Stimulation, Chemical; Verapamil | 1976 |
Effects of atrio-ventricular conduction of calcium-antagonistic coronary vasodilators, local anaesthetics and quinidine injected into the posterior and the anterior septal artery of the atrio-ventricular node preparation of the dog.
Topics: Action Potentials; Anesthetics, Local; Animals; Atrioventricular Node; Benzazepines; Calcium; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Female; Heart Conduction System; In Vitro Techniques; Injections; Lidocaine; Male; Neural Conduction; Nifedipine; Procaine; Quinidine; Vasodilator Agents; Verapamil | 1976 |
Effect of drugs in the wolff-parkinson-white syndrome.
Topics: Ajmaline; Digitalis Glycosides; Electric Stimulation; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Verapamil; Wolff-Parkinson-White Syndrome | 1975 |
Mechanism of action of antidysrhythmic drugs on ventricular conduction as studied with intramural electrodes.
Topics: Ajmaline; Animals; Disopyramide; Dogs; Electrocardiography; Heart Conduction System; Hydroxyzine; Lidocaine; Oxprenolol; Phenytoin; Propranolol; Purkinje Fibers; Quinidine; Verapamil | 1975 |
Functional differentiation of the transmembrane sodium and calcium channels in mammalian cardiac fibers by use of specific inhibitors.
Topics: Animals; Calcium; Cats; Electric Conductivity; Gallopamil; Heart; In Vitro Techniques; Lidocaine; Membrane Potentials; Metals, Alkaline Earth; Myocardial Contraction; Myocardium; Sodium; Strontium; Verapamil | 1975 |
[Treatment of arrhythmia in general practice].
Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Humans; Isoproterenol; Lidocaine; Myocardial Infarction; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine; Tachycardia; Verapamil | 1975 |
Electrophysiologic properties of antidysrhythmic drugs as a rational basis for therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Hemodynamics; Humans; Lidocaine; Osmolar Concentration; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1976 |
Pharmacology of the myocardium: antiarrhythmic therapy.
Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Lidocaine; Membrane Potentials; Myocardium; Procainamide; Quinidine; Sodium; Verapamil | 1976 |
[A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)].
Topics: Acidosis; Adult; Calcium; Cryotherapy; Glucose; Halothane; Humans; Insulin; Lidocaine; Male; Malignant Hyperthermia; Methylprednisolone; Muscle Relaxants, Central; Oxygen; Succinylcholine; Verapamil | 1976 |
Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes.
Topics: Action Potentials; Adolescent; Cardiac Pacing, Artificial; Epinephrine; Female; Heart Conduction System; Humans; Lidocaine; Long QT Syndrome; Menstruation; Propranolol; Stress, Psychological; Syncope; Torsades de Pointes; Verapamil | 1992 |
Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes.
Topics: Animals; Chlorpromazine; Dipyridamole; Disopyramide; Drug Interactions; In Vitro Techniques; Lidocaine; Liver; Male; Nifedipine; Ouabain; Propranolol; Quinidine; Rats; Rats, Wistar; Sodium; Taurocholic Acid; Verapamil | 1992 |
Spontaneous cluster formation of dendritic (veiled) cells and lymphocytes from skin lymph obtained from dogs with chronic lymphedema.
Topics: Animals; Anti-Inflammatory Agents; Dendritic Cells; Dogs; Edetic Acid; Immunosuppressive Agents; Lidocaine; Lymph; Lymphatic System; Lymphedema; Lymphocytes; Skin; Tretinoin; Verapamil | 1992 |
[Comparison of antiarrhythmic effects of IHC-72 (an iodonium-72), lidocaine and verapamil].
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Edetic Acid; Female; Guinea Pigs; Lidocaine; Male; Mice; Myocardial Reperfusion Injury; Onium Compounds; Ouabain; Rats; Rats, Inbred Strains; Ventricular Fibrillation; Verapamil | 1992 |
Modification by hypoxia, hyperkalaemia and acidosis of the cardiac electrophysiological effects of a range of antiarrhythmic drugs.
Topics: Acidosis; Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Electrophysiology; Heart; Hyperkalemia; Hypoxia; In Vitro Techniques; Lidocaine; Propanolamines; Propranolol; Purkinje Fibers; Sheep; Verapamil | 1992 |
Epicardial His bundle recordings in the guinea pig in vivo.
Topics: Animals; Atrioventricular Node; Blood Pressure; Bundle of His; Electrocardiography; Electrodes; Electrophysiology; Female; Guinea Pigs; Heart Rate; Lidocaine; Male; Pericardium; Verapamil | 1992 |
Age-related effects of ischemia, lidocaine and verapamil on overdrive-induced suppression of ventricular pacemakers in isolated rat heart.
Topics: Aging; Animals; Coronary Disease; In Vitro Techniques; Lidocaine; Male; Rats; Rats, Inbred Strains; Ventricular Function; Verapamil | 1992 |
Effects and mechanism of low [K]o on the critical potential of effective refractory period in guinea pig ventricular muscle cells.
Topics: Animals; Drug Interactions; Female; Guinea Pigs; Heart; Lidocaine; Male; Membrane Potentials; Myocardial Contraction; Potassium; Refractory Period, Electrophysiological; Verapamil | 1992 |
Programmed electrical stimulation and drugs identify two subgroups of ventricular tachycardias occurring 16-24 hours after occlusion of the left anterior descending artery.
Topics: Animals; Arterial Occlusive Diseases; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Electrocardiography; Electrophysiology; Female; Flunarizine; Lidocaine; Male; Tachycardia; Time Factors; Verapamil | 1992 |
Effects of lidocaine and verapamil on defibrillation in humans.
Topics: Adult; Blood Pressure; Electric Countershock; Electrocardiography; Female; Heart; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Ventricular Fibrillation; Verapamil | 1991 |
Characteristics of electrocardiographic changes with some representative antiarrhythmic drugs in adult rats.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiography; Heart; Lidocaine; Male; Procainamide; Propranolol; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Inhibition by cocaine of excitation-contraction coupling in isolated cardiomyocytes.
Topics: Animals; Calcium; Cell Separation; Cocaine; Dose-Response Relationship, Drug; Electric Conductivity; Heart; Lidocaine; Membrane Potentials; Myocardial Contraction; Myocardium; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Sodium Channels; Sympathetic Nervous System; Tetrodotoxin; Verapamil | 1991 |
Influence of lignocaine on plasma protein binding and pharmacokinetics of verapamil in dogs.
Topics: Animals; Blood Proteins; Dogs; Hydrogen-Ion Concentration; Indocyanine Green; Infusions, Intravenous; Lidocaine; Protein Binding; Verapamil | 1990 |
Effects of beta-antagonists on contraction of bovine retinal microarteries in vitro.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Capillaries; Cattle; Hydroxydopamines; In Vitro Techniques; Isometric Contraction; Lidocaine; Muscle, Smooth, Vascular; Oxidopamine; Propranolol; Retinal Artery; Serotonin; Timolol; Vasoconstriction; Verapamil | 1990 |
Time courses of lidocaine effects on sodium membrane currents in small and large neurons.
Topics: Action Potentials; Animals; Animals, Newborn; Cells, Cultured; Ganglia; Ganglia, Spinal; Helix, Snails; In Vitro Techniques; Lidocaine; Neurons; Rats; Sodium Channels; Verapamil | 1990 |
[Electrophysiologic study of ischemic ventricular arrhythmia].
Topics: Animals; Dogs; Electrophysiology; Female; Heart; Humans; Lidocaine; Male; Myocardial Infarction; Tachycardia; Verapamil | 1990 |
Effects of lidocaine, disopyramide and verapamil on the in vivo triggered ventricular arrhythmia in digitalized canine heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Verapamil | 1990 |
Use-dependent action of antiarrhythmic drugs in frog skeletal muscle and canine cardiac Purkinje fiber.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; In Vitro Techniques; Kinetics; Lidocaine; Microelectrodes; Muscle Contraction; Muscles; Purkinje Fibers; Quinidine; Rana esculenta; Tetrodotoxin; Verapamil | 1990 |
Uptake of catamphiphilic drugs into erythrocytes and muscular tissue correlates to membrane enrichment and to 45Ca displacement from phosphatidylserine monolayers.
Topics: Binding Sites; Calcium; Cell Membrane; Diltiazem; Erythrocytes; Flunarizine; Humans; In Vitro Techniques; Lidocaine; Muscles; Nitrendipine; Phosphatidylserines; Verapamil | 1990 |
Action of antiepileptic and anaesthetic drugs on Na- and Ca-spikes in mammalian non-myelinated axons.
Topics: Action Potentials; Anesthetics; Animals; Anticonvulsants; Axons; Calcium; Carbamazepine; Dose-Response Relationship, Drug; Flurazepam; Lidocaine; Procaine; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1990 |
Phosphatidylserine monolayers as models for drug uptake into membranes and tissue.
Topics: Animals; Aorta; Benzothiazoles; Cell Membrane; Diltiazem; Erythrocyte Membrane; Flunarizine; Heart Atria; Humans; Lidocaine; Membranes, Artificial; Models, Biological; Nitrendipine; Pharmaceutical Preparations; Pharmacokinetics; Phosphatidylserines; Piperidines; Rats; Thiazoles; Verapamil | 1990 |
Influence of protective drugs on the EEG during short-term transient ischaemia.
Topics: Animals; Dogs; Electroencephalography; Ischemic Attack, Transient; Lidocaine; Phenytoin; Piracetam; Pyridoxine; Thiopental; Verapamil | 1990 |
Triggered activity induced by combined mild hypoxia and acidosis in guinea-pig Purkinje fibers.
Topics: Acidosis; Animals; Arrhythmias, Cardiac; Calcium; Female; Guinea Pigs; Heart Conduction System; Hypoxia; In Vitro Techniques; Ion Channels; Lidocaine; Male; Norepinephrine; Purkinje Fibers; Verapamil | 1986 |
Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Dogs; Electrocardiography; Heart Rate; Heart Ventricles; Infusions, Intravenous; Lidocaine; Male; Myocardial Infarction; Verapamil | 1988 |
Pituitary thyrotropin-releasing hormone receptors: local anesthetic effects on binding and responses.
Topics: Anesthetics, Local; Animals; Benzocaine; Chlordiazepoxide; Chlorpromazine; Dibucaine; Hydrogen-Ion Concentration; Imipramine; Lidocaine; Pituitary Gland; Procaine; Prolactin; Propranolol; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetracaine; Thyrotropin-Releasing Hormone; Trifluoperazine; Verapamil | 1989 |
[Therapy of acute myocardial infarct].
Topics: Acidosis; Analgesics; Atropine; Bicarbonates; Bradycardia; Cardiac Complexes, Premature; Critical Care; Diazepam; Digitalis Glycosides; Early Ambulation; First Aid; Furosemide; Heparin; Humans; Hypertension; Lidocaine; Myocardial Infarction; Nitroglycerin; Pacemaker, Artificial; Positive-Pressure Respiration; Sodium; Sodium Bicarbonate; Verapamil | 1985 |
The antiarrhythmic activity of N-alkyl-1,2-diphenylethanolamines.
Topics: Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Ethanolamines; Lidocaine; Male; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Hydrostatic distention and pharmacological treatment of epinephrine-induced microarterial spasm.
Topics: Animals; Chlorpromazine; Constriction, Pathologic; Epinephrine; Femoral Artery; Isotonic Solutions; Lidocaine; Rabbits; Sodium Chloride; Vasodilator Agents; Verapamil | 1989 |
Influence of lidocaine on plasma protein binding and pharmacokinetics of verapamil in dogs.
Topics: Animals; Blood Proteins; Chromatography, High Pressure Liquid; Dogs; Injections, Intravenous; Lidocaine; Metabolic Clearance Rate; Organophosphorus Compounds; Orosomucoid; Verapamil | 1989 |
Basic dysrhythmias.
Topics: Humans; Lidocaine; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome | 1989 |
The effect of drugs and lead maturation on atrial electrograms during sinus rhythm and atrial fibrillation.
Topics: Algorithms; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Dogs; Electric Countershock; Electrocardiography; Electrodes, Implanted; Heart Conduction System; Heart Rate; Isoproterenol; Lidocaine; Propranolol; Signal Processing, Computer-Assisted; Verapamil | 1989 |
Cardiovascular interactions of lidocaine with verapamil or diltiazem in the dog.
Topics: Animals; Diltiazem; Dogs; Drug Interactions; Female; Hemodynamics; Lidocaine; Male; Verapamil | 1988 |
Verapamil increases the toxicity of local anesthetics.
Topics: Animals; Bupivacaine; Dose-Response Relationship, Drug; Drug Synergism; Female; Lethal Dose 50; Lidocaine; Mice; Verapamil | 1988 |
Ion shifts in myocardial cells during ischemia and reperfusion and the effect of membrane stabilizing agents on ischemic ion transport.
Topics: Animals; Biological Transport, Active; Calcium; Cations; Cell Membrane Permeability; Coronary Disease; Guinea Pigs; In Vitro Techniques; Intracellular Fluid; Lidocaine; Myocardium; Potassium; Quinidine; Sodium; Verapamil | 1987 |
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduction System; Lidocaine; Male; Metoprolol; Myocardial Infarction; Sotalol; Ventricular Fibrillation; Verapamil | 1987 |
Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.
Topics: Cell Survival; Chlorpromazine; Drug Resistance; Drug Synergism; Haloperidol; Humans; Imipramine; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Lidocaine; Protein Kinase C; Tamoxifen; Tumor Cells, Cultured; Verapamil | 1987 |
[ Action of low doses of vincristine, lidocaine and verapamil on DNA replication in vitro].
Topics: Adult; Aged; Cells, Cultured; Culture Media; DNA Replication; Doxorubicin; Drug Combinations; Female; Humans; Leukemia, Lymphoid; Lidocaine; Lymphocytes; Male; Middle Aged; T-Lymphocytes; Verapamil; Vincristine | 1986 |
Caffeine-induced contraction in vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; In Vitro Techniques; Lidocaine; Magnesium; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium; Procaine; Rabbits; Verapamil | 1987 |
[Value of using verapamil in coronary reperfusion arrhythmias].
Topics: Aged; Arrhythmias, Cardiac; Drug Therapy, Combination; Female; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Urokinase-Type Plasminogen Activator; Verapamil | 1987 |
A case of idiopathic sustained ventricular tachycardia of about 70 days' duration.
Topics: Adult; Alcoholism; Electrocardiography; Female; Heart Failure; Humans; Lidocaine; Tachycardia; Verapamil | 1986 |
Pharmacodynamic and pharmacokinetic interactions between lidocaine and verapamil.
Topics: Animals; Blood Pressure; Cardiac Output; Carotid Arteries; Coronary Circulation; Dogs; Drug Interactions; Heart Rate; Hemodynamics; Lidocaine; Renal Circulation; Vascular Resistance; Verapamil | 1987 |
Circus movement tachycardia induced by a single premature stimulus on the ventricular sheet--evaluation of the leading circle hypothesis in the canine ventricular muscle.
Topics: Action Potentials; Animals; Dogs; Electric Stimulation; Electrodes; Electrophysiology; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Lidocaine; Refractory Period, Electrophysiological; Tachycardia; Verapamil | 1986 |
An experimental approach to the choice of antiarrhythmic therapy.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cats; Coronary Disease; Diltiazem; Lidocaine; Mexiletine; Nifedipine; Phenoxybenzamine; Prazosin; Propafenone; Propiophenones; Propranolol; Stellate Ganglion; Verapamil | 1986 |
Atrioventricular junctional escape rhythm suppressed by verapamil: evidence suggesting abnormal automaticity.
Topics: Aged; Arrhythmias, Cardiac; Atrioventricular Node; Cardiac Pacing, Artificial; Electrocardiography; Heart Conduction System; Humans; Lidocaine; Male; Myocardial Infarction; Sinoatrial Node; Verapamil | 1986 |
The effect of lidocaine compared with verapamil on the enhanced ventricular rhythm in the infarcted canine heart.
Topics: Animals; Dogs; Female; Heart; Heart Block; Heart Rate; Heart Ventricles; Lidocaine; Male; Myocardial Infarction; Propranolol; Ventricular Function; Verapamil | 1986 |
External pH dependency of delayed afterdepolarization in rabbit myocardium.
Topics: Animals; Doxorubicin; Electrophysiology; Female; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Lidocaine; Male; Norepinephrine; Papillary Muscles; Rabbits; Verapamil | 1986 |
Ventricular automaticity at the onset of the late phase of coronary artery occlusion in canine hearts and the effects of lidocaine and verapamil.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vessels; Dogs; Electrophysiology; Lidocaine; Ligation; Verapamil | 1986 |
Edrophonium antagonizes combined lidocaine-pancuronium and verapamil-pancuronium neuromuscular blockade in cats.
Topics: Animals; Cats; Edrophonium; Infusions, Intravenous; Infusions, Parenteral; Injections, Intravenous; Lidocaine; Muscle Contraction; Neuromuscular Junction; Pancuronium; Verapamil | 1986 |
Triggered activity as a possible mechanism of ventricular tachycardia in mitral valve prolapse.
Topics: Adolescent; Cardiac Pacing, Artificial; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Male; Mitral Valve Prolapse; Tachycardia; Verapamil | 1986 |
Characterization of the class I antiarrhythmic activity of cibenzoline succinate in guinea pig papillary muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Imidazoles; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Time Factors; Verapamil | 1987 |
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil | 1985 |
An unusual ventricular tachycardia responsive to verapamil.
Topics: Adult; Amiodarone; Bundle-Branch Block; Electrocardiography; Heart Ventricles; Humans; Lidocaine; Male; Tachycardia; Verapamil | 1986 |
The efficacy of lidocaine and verapamil alone and in combination on spontaneously occurring automatic ventricular tachycardia in conscious dogs one day after right coronary artery occlusion.
Topics: Animals; Arterial Occlusive Diseases; Blood Pressure; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Drug Combinations; Electrophysiology; Female; Lidocaine; Male; Tachycardia; Time Factors; Verapamil | 1986 |
Effect of verapamil & lignocaine on prostaglandin induced contractions in isolated rat uterus.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Female; In Vitro Techniques; Lidocaine; Prostaglandins; Rats; Time Factors; Tromethamine; Uterine Contraction; Verapamil | 1985 |
Cardiovascular and respiratory effects of antiarrhythmic drugs on conscious beagles.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Disopyramide; Dogs; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Lidocaine; Male; Phenytoin; Procainamide; Respiration; Verapamil | 1985 |
Lack of interaction between verapamil and cimetidine.
Topics: Administration, Oral; Adult; Biological Availability; Blood Proteins; Chromatography, Gas; Cimetidine; Drug Administration Schedule; Drug Interactions; Electrocardiography; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Lidocaine; Male; Random Allocation; Verapamil | 1985 |
Effects of verapamil and lidocaine in a canine model of sudden coronary death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden; Dogs; Female; Heart Conduction System; Heart Rate; Lidocaine; Male; Myocardial Infarction; Premedication; Ventricular Fibrillation; Verapamil | 1985 |
Effects of lidocaine, procaine, procainamide and quinidine on electrophysiological properties of cultured embryonic chick hearts.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Chick Embryo; Electric Stimulation; Heart; Heart Ventricles; Histamine; Isoproterenol; Lidocaine; Membrane Potentials; Organ Culture Techniques; Procainamide; Procaine; Propranolol; Quinidine; Verapamil | 1985 |
[What is assured in the treatment of heart arrhythmia?].
Topics: Adrenergic beta-Antagonists; Ajmaline; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Cardiac Complexes, Premature; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1972 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Premature; Digitalis Glycosides; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Tachycardia; Ventricular Fibrillation; Verapamil | 1973 |
[Modern therapy of cardiac arrhythmias].
Topics: Adrenergic beta-Antagonists; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1973 |
[The treatment of cardiac arrhythmias: complexity and schematization].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Benzofurans; Digitalis Glycosides; Electric Countershock; Lidocaine; Phenytoin; Potassium; Procainamide; Quinidine; Tachycardia; Verapamil | 1973 |
[Influence of active antiarrhythmia substances on refractory period and contractility of guinea pig atria].
Topics: Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Muscle Contraction; Nitriles; Phenytoin; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Reaction Time; Sparteine; Vasodilator Agents; Verapamil | 1969 |
Actions of antiarrhythmic drugs on refractory period and contractility of isolated rat and guinea-pig atria.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Ethers; Ethylamines; Glycerol; Guinea Pigs; Heart Atria; Lidocaine; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Rats; Sparteine; Verapamil | 1971 |
[Clinical pharmacology and adverse effects of various anti-arrhythmic drugs].
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Bone Marrow Diseases; Central Nervous System Diseases; Female; Gastrointestinal Diseases; Heart Diseases; Hemodynamics; Humans; Imidazoles; Isoproterenol; Lidocaine; Membrane Potentials; Phenytoin; Plants, Medicinal; Procainamide; Quinidine; Rauwolfia; Verapamil | 1971 |
[Action of anti-arrhythmia agents on intracardiac conduction].
Topics: Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Benzofurans; Bundle of His; Cardiac Catheterization; Depression, Chemical; Diethylamines; Dogs; Electrocardiography; Heart Conduction System; Indans; Iodobenzoates; Lidocaine; Lidoflazine; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1974 |
Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors.
Topics: Animals; Biological Transport, Active; Calcium; Cats; Cell Membrane Permeability; Lidocaine; Muscle Contraction; Myocardium; Procaine; Sodium; Verapamil | 1972 |
[Some suggestions for the treatment of myocardial infarct in the pre-hospitalization phase].
Topics: Allied Health Personnel; Ambulances; Angina Pectoris; Arrhythmias, Cardiac; Atropine; Droperidol; Health Education; Heart Arrest; Humans; Lidocaine; Metaproterenol; Morphine; Myocardial Infarction; Shock, Cardiogenic; Time Factors; Verapamil; Vomiting | 1973 |
Experimental evaluation of antiarrhythmic drugs in the guinea pig.
Topics: Aconitum; Ajmaline; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Guinea Pigs; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine; Strophanthins; Verapamil | 1973 |
[Verapamil treatment in myocardial infarction with relapsing ventricular tachycardia].
Topics: Aged; Angina Pectoris; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Humans; Infusions, Parenteral; Injections, Intravenous; Lidocaine; Male; Myocardial Infarction; Recurrence; Tachycardia; Time Factors; Verapamil | 1973 |
[Plasma and tissue catecholamine concentration and antiarrhythmic influence on it].
Topics: Animals; Anti-Arrhythmia Agents; Catecholamines; Humans; Lidocaine; Male; Pindolol; Practolol; Rats; Verapamil | 1973 |
[Effect of quinidine, iproveratril, lidocaine and sparteine on ECG and circulatory system of the anesthetized cat].
Topics: Anesthesia; Animals; Blood Pressure; Cats; Drug Interactions; Electrocardiography; Heart; Heart Rate; Hemodynamics; Injections, Intraperitoneal; Lidocaine; Male; Pentobarbital; Quinidine; Sinoatrial Node; Sparteine; Verapamil | 1973 |
Present status and treatment of paroxysmal supraventricular tachycardia.
Topics: Child; Child, Preschool; Digoxin; Electric Countershock; Electrocardiography; Humans; Infant; Lidocaine; Pacemaker, Artificial; Posture; Procainamide; Propranolol; Tachycardia, Paroxysmal; Valsalva Maneuver; Verapamil | 1972 |
[Disturbances of cardiac rhythm and their treatment].
Topics: Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Digitoxin; Digoxin; Humans; Lidocaine; Metaproterenol; Middle Aged; Phenytoin; Procainamide; Quinidine; Reserpine; Verapamil | 1970 |
[Differential therapy of tachycardial arrhythmias].
Topics: Anti-Arrhythmia Agents; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Quinidine; Reserpine; Sparteine; Sympatholytics; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1969 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
Relative inotropic and arrhythmogenic effects of five cardiac steroids in ventricular myocardium: oscillatory afterpotentials and the role of endogenous catecholamines.
Topics: Action Potentials; Adrenergic beta-Antagonists; Amantadine; Animals; Arrhythmias, Cardiac; Cardiac Glycosides; Catecholamines; Drug Interactions; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Lidocaine; Myocardial Contraction; Verapamil | 1981 |
[Effects of anti-arrhythmia agents on heart rate. Significance and importance].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil | 1981 |
Antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil | 1983 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil | 1984 |
Antiarrhythmic therapy: new additions and future expectations.
Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Bretylium Tosylate; Disopyramide; Encainide; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil | 1983 |
Arterial spasm during renal angioplasty.
Topics: Adolescent; Adult; Aged; Angioplasty, Balloon; Arterial Occlusive Diseases; Arteriosclerosis; Child; Female; Fibromuscular Dysplasia; Heparin; Humans; Lidocaine; Male; Middle Aged; Nifedipine; Nitroglycerin; Premedication; Renal Artery; Spasm; Tolazoline; Verapamil | 1983 |
Interactions of D600 (methoxyverapamil) and local anesthetics with rat brain alpha-adrenergic and muscarinic receptors.
Topics: Anesthetics, Local; Animals; Gallopamil; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lidocaine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Muscarinic; Tetracaine; Verapamil | 1980 |
[The dynamics of glycerol and cAMP release from perfused isolated rat fat cells with epinephrine stimulation (author's transl)].
Topics: Adipose Tissue; Animals; Calcium; Cyclic AMP; Dinitrophenols; Epinephrine; Glycerol; In Vitro Techniques; Lidocaine; Male; Rats; Verapamil | 1980 |
[Cellular effects of anti-arrhythmia drugs. Their predictive value of therapeutic effects].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Catecholamines; Electrolytes; Heart Conduction System; Humans; Ion Channels; Lidocaine; Prognosis; Quinidine; Verapamil | 1981 |
Modification of "depressed fast channel dependent slow conduction" by lidocaine and verapamil in the presence or absence of catecholamines--evidence for alteration of preferential ionic channels for slow conduction.
Topics: Action Potentials; Animals; Catecholamines; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Ion Channels; Isoproterenol; Lidocaine; Microelectrodes; Myocardial Infarction; Papillary Muscles; Pindolol; Potassium; Verapamil | 1983 |
A pharmacological evaluation of electrical events in the myocardium.
Topics: Animals; Calcium; Cardiac Output; Coronary Circulation; Dogs; Electrocardiography; Heart; Heart Rate; Ion Channels; Lidocaine; Myocardial Contraction; Myocardium; Pindolol; Potassium; Purkinje Fibers; Rabbits; Sinoatrial Node; Sodium-Potassium-Exchanging ATPase; Verapamil | 1982 |
Nature of "residual fast channel" dependent action potentials and slow conduction in guinea pig ventricular muscle and its modification by isoproterenol.
Topics: Action Potentials; Animals; Guinea Pigs; Heart; Heart Conduction System; Ion Channels; Isoproterenol; Lidocaine; Papillary Muscles; Verapamil | 1983 |
The effects of calcium channel inhibitors on twitches and noradrenaline contractions of the rat bisected vas deferens.
Topics: Animals; Calcium Channel Blockers; In Vitro Techniques; Ion Channels; Lidocaine; Male; Muscle Contraction; Nifedipine; Nitroprusside; Norepinephrine; Rats; Vas Deferens; Verapamil | 1983 |
Acute effects of anti-arrhythmic drugs on cardiac pacing threshold.
Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrophysiology; Female; Heart; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Propranolol; Verapamil | 1984 |
Influence of papaverine on spontaneous activity of isolated right atria from small mammals.
Topics: Action Potentials; Animals; Depression, Chemical; Drug Interactions; Female; Guinea Pigs; Heart Atria; Heart Rate; Lidocaine; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Papaverine; Rabbits; Rats; Rats, Inbred Strains; Sinoatrial Node; Verapamil | 1984 |
The interaction of cycle length with the electrophysiological effect of lidocaine, tocainide and verapamil on canine Purkinje fibers.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Dogs; Electric Stimulation; Electrophysiology; Female; Heart Conduction System; Lidocaine; Male; Purkinje Fibers; Time Factors; Tocainide; Verapamil | 1984 |
Cycle length-dependent action potential duration in canine cardiac Purkinje fibers.
Topics: Action Potentials; Animals; Cobalt; Dogs; Female; Heart Conduction System; Homeostasis; In Vitro Techniques; Isoproterenol; Kinetics; Lidocaine; Male; Purkinje Fibers; Reaction Time; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1984 |
Electromechanical effects of bepridil on rabbit isolated hearts.
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bepridil; Bundle of His; Electric Stimulation; Electrophysiology; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Pyrrolidines; Rabbits; Verapamil | 1984 |
The beneficial effect of nicardipine compared with nifedipine and verapamil in limiting myocardial infarct size in baboons.
Topics: Animals; Calcium Channel Blockers; Female; Hemodynamics; Lidocaine; Male; Myocardial Infarction; Nicardipine; Nifedipine; Nitroblue Tetrazolium; Papio; Pyridines; Verapamil | 1983 |
Overdrive suppression of conduction in the canine His-Purkinje system after occlusion of the anterior septal artery.
Topics: Animals; Bundle of His; Cardiac Pacing, Artificial; Coronary Disease; Dogs; Heart Block; Heart Conduction System; Isoproterenol; Lidocaine; Purkinje Fibers; Verapamil | 1984 |
Advances in antiarrhythmic therapy. The role of newer antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Atrioventricular Node; Humans; Lidocaine; Mexiletine; Tocainide; Verapamil | 1982 |
[Pharmacologic evaluation of electrical processes in the myocardium].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Electrophysiology; Heart; Heart Conduction System; In Vitro Techniques; Lidocaine; Nitroglycerin; Pindolol; Verapamil | 1982 |
Availability of electrophysiological approach to the selection and assessment of antiarrhythmic drugs for recurrent ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Procainamide; Recurrence; Tachycardia; Verapamil | 1983 |
Quantitative analysis of the antiarrhythmic effect of drugs on canine ventricular arrhythmias by the determination of minimum effective plasma concentrations.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Dogs; Female; Lidocaine; Male; Mexiletine; Phenytoin; Verapamil | 1983 |
Verapamil plasma binding: relationship to alpha 1-acid glycoprotein and drug efficacy.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Lidocaine; Male; Orosomucoid; Propranolol; Protein Binding; Verapamil | 1983 |
Study of the ventricular antifibrillatory effects of calcium channel blocking agents in comparison with lidocaine on canine normal heart in situ.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Diltiazem; Dogs; Female; Heart; Heart Conduction System; Lidocaine; Male; Myocardial Contraction; Risk; Sinoatrial Node; Verapamil | 1983 |
Idiopathic paroxysmal ventricular tachycardia with a QRS pattern of right bundle branch block and left axis deviation: a unique clinical entity with specific properties.
Topics: Adult; Bundle-Branch Block; Electrocardiography; Female; Humans; Injections, Intravenous; Lidocaine; Male; Propranolol; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1983 |
The effects of lidocaine and verapamil on overdrive-induced suppression of pacemakers in dogs with complete atrioventricular block.
Topics: Animals; Atrioventricular Node; Blood Pressure; Dogs; Electric Stimulation; Heart Block; Heart Conduction System; Heart Ventricles; Lidocaine; Purkinje Fibers; Verapamil | 1983 |
[Clinical pharmacology of anti-arrhythmia agents].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Humans; Lidocaine; Quinidine; Verapamil | 1983 |
Amantadine-induced diastolic depolarization and automaticity in ventricular muscle.
Topics: Action Potentials; Amantadine; Animals; Catecholamines; Cats; Diastole; Dogs; Electrophysiology; Heart; Lidocaine; Membrane Potentials; Rabbits; Rana pipiens; Tetrodotoxin; Ventricular Function; Verapamil | 1982 |
Fast and slow idioventricular rhythms in the canine heart: a study of their mechanism using antiarrhythmic drugs and electrophysiologic testing.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Electrophysiology; Formaldehyde; Heart Block; Heart Conduction System; Lidocaine; Membrane Potentials; Moricizine; Phenothiazines; Verapamil | 1982 |
Method for evaluating the effects of antiarrhythmic drugs on ventricular tachycardias with different electrophysiologic characteristics and different mechanisms in the infarcted canine heart.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrophysiology; Female; Isoproterenol; Lidocaine; Male; Myocardial Infarction; Procainamide; Tachycardia; Verapamil | 1982 |
[Emergency therapy of cardiac arrhythmias. Statistico-clinical evaluation of verapamil (clinical note)].
Topics: Acute Disease; Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Bunaftine; Female; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Verapamil | 1982 |
Prediction of bioavailability for drugs with a high first-pass effect using oral clearance data.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Kinetics; Lidocaine; Pharmaceutical Preparations; Propranolol; Verapamil | 1982 |
Comparison of lidocaine and verapamil on vascular smooth muscle.
Topics: Humans; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Verapamil | 1982 |
Canine-effective plasma concentrations of antiarrhythmic drugs on the two-stage coronary ligation arrhythmia.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Dose-Response Relationship, Drug; Isoquinolines; Lidocaine; Ligation; Phenytoin; Propanolamines; Verapamil | 1982 |
Effects of calcium antagonists and lidocaine on conduction delay induced by acute myocardial ischemia in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Coronary Disease; Diltiazem; Dogs; Heart Conduction System; Lidocaine; Time Factors; Verapamil | 1980 |
Antiarrhythmic evaluation of verapamil, nifedipine, perhexiline and skf 525-A in four canine models of cardiac arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Dogs; Female; Heart Rate; Lidocaine; Male; Myocardial Contraction; Nifedipine; Perhexiline; Piperidines; Proadifen; Pyridines; Verapamil | 1981 |
[Steady state and time-dependent slowing and conduction in acute myocardial ischemia-effect of lidocaine and verapamil (author's transl)].
Topics: Animals; Coronary Disease; Dogs; Lidocaine; Myocardial Contraction; Time Factors; Verapamil | 1980 |
Myocardial conduction time and antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dogs; Electrophysiology; Heart Conduction System; Lidocaine; Quinidine; Ventricular Function; Verapamil | 1981 |
Exercise-triggered paroxysmal ventricular tachycardia. A repetitive rhythmic activity possibly related to afterdepolarization.
Topics: Adult; Electrophysiology; Exercise Test; Heart; Humans; Isoproterenol; Lidocaine; Male; Middle Aged; Physical Exertion; Propranolol; Tachycardia, Paroxysmal; Verapamil | 1981 |
Antiarrhythmic drugs.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Therapy, Combination; Humans; Lidocaine; Quinidine; Verapamil | 1981 |
Effects of tetrodotoxin, lidocaine, verapamil, and AHR-2666 on Ouabain-induced delayed afterdepolarizations in canine Purkinje fibers.
Topics: Action Potentials; Animals; Carbamates; Diastole; Dogs; Heart Conduction System; Ion Channels; Lidocaine; Ouabain; Purkinje Fibers; Pyrrolidines; Tetrodotoxin; Time Factors; Verapamil | 1980 |
Mechanisms for impulse initiation in isolated human atrial fibers.
Topics: Acetylcholine; Action Potentials; Adolescent; Adult; Carbamates; Child; Child, Preschool; Electrophysiology; Epinephrine; Heart Atria; Heart Conduction System; Heart Rate; Humans; Infant; Lidocaine; Middle Aged; Myocardial Contraction; Pyrrolidines; Tetrodotoxin; Time Factors; Verapamil | 1980 |
Failure of antiarrhythmic drugs to prevent experimental reperfusion ventricular fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Dogs; Lidocaine; Ligation; Perfusion; Procainamide; Ventricular Fibrillation; Verapamil | 1981 |
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect.
Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil | 1995 |
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil | 1995 |
Regional oxygen consumption persists in dyskinetic canine myocardium.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Citrates; Coronary Circulation; Diacetyl; Dogs; Heart Rate; Infusions, Intra-Arterial; Lidocaine; Myocardial Contraction; Myocardial Ischemia; Oxygen Consumption; Verapamil | 1994 |
The effect of nickel chloride on the isolated hemidiaphragm of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Isometric Contraction; Lidocaine; Male; Nickel; Rats; Time Factors; Verapamil | 1995 |
Contractions in guinea-pig ventricular myocytes triggered by a calcium-release mechanism separate from Na+ and L-currents.
Topics: Animals; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Lidocaine; Male; Membrane Potentials; Myocardial Contraction; Nickel; Patch-Clamp Techniques; Ryanodine; Sodium Channels; Verapamil | 1995 |
Hyperpolarization induced by sodium removal in rabbit sinoatrial node cells. Possible role of electrogenic sodium-calcium exchange.
Topics: Animals; Calcium; In Vitro Techniques; Lidocaine; Membrane Potentials; Ouabain; Quinacrine; Quinidine; Rabbits; Sinoatrial Node; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1995 |
Effects of K+ channel blockers on inwardly and outwardly rectifying whole-cell K+ currents in sheep parotid secretory cells.
Topics: Animals; Barium; Cesium; Charybdotoxin; In Vitro Techniques; Lidocaine; Membrane Potentials; Parotid Gland; Potassium; Potassium Channels; Quinidine; Quinine; Scorpion Venoms; Sheep; Tetraethylammonium; Tetraethylammonium Compounds; Verapamil | 1993 |
R 56 865, a Na+/Ca(2+)-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Benzothiazoles; Calcium; Dose-Response Relationship, Drug; Hemodynamics; Lidocaine; Male; Piperidines; Random Allocation; Rats; Rats, Wistar; Sodium; Sodium Channels; Tetrodotoxin; Thiazoles; Verapamil | 1993 |
Transcainide causes two modes of open-channel block with different voltage sensitivities in batrachotoxin-activated sodium channels.
Topics: Animals; Anti-Arrhythmia Agents; Batrachotoxins; Biophysical Phenomena; Biophysics; Cattle; Electrochemistry; In Vitro Techniques; Kinetics; Lidocaine; Membrane Potentials; Muscle, Skeletal; Myocardium; Rats; Sodium; Sodium Channel Blockers; Sodium Channels; Verapamil | 1994 |
Effect of levamisole hydrochloride on the guinea-pig atrium.
Topics: Animals; Arrhythmias, Cardiac; Atropine; Disease Models, Animal; Drug Antagonism; Drug Evaluation, Preclinical; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Hexamethonium; In Vitro Techniques; Levamisole; Lidocaine; Male; Practolol; Verapamil | 1993 |
Effects of verapamil on spinal anesthesia with local anesthetics.
Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Lidocaine; Male; Motor Activity; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Tetracaine; Verapamil | 1995 |
[Effects of lidocaine on contraction of isolated rabbit aortic rings].
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Female; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Verapamil | 1994 |
Role of junctional zone cells between Purkinje fibres and ventricular muscle in arrhythmogenesis.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Dogs; Edetic Acid; Female; Heart Ventricles; Lidocaine; Male; Membrane Potentials; Myocardium; Purkinje Fibers; Tetrodotoxin; Verapamil | 1994 |
Effects of 3,6-dimethylamino-dibenzopyriodonium edetate on action potentials in guinea pig papillary muscles.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Edetic Acid; Female; Guinea Pigs; Lidocaine; Male; Onium Compounds; Papillary Muscles; Verapamil | 1993 |
Comparative efficacy of antiarrhythmic agents in preventing halothane-epinephrine arrhythmias in rats.
Topics: Amiodarone; Anesthesia, Inhalation; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Epinephrine; Flecainide; Halothane; Isoflurane; Lidocaine; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Skin dendritic cell-lymphocyte interactions in autologous system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Cell Adhesion; Dendritic Cells; Deoxyribonucleases; Dogs; Edetic Acid; Endopeptidases; Epidermis; Heparin; Immunosuppressive Agents; Lidocaine; Lymph; Lymphedema; Lymphocytes; Neuraminidase; Sodium Azide; Tretinoin; Verapamil | 1993 |
Induction and the possible mechanism of ventricular tachycardia after catheter ablation with direct current shocks in dogs.
Topics: Animals; Bundle of His; Cardiac Pacing, Artificial; Catheter Ablation; Dogs; Electrocardiography, Ambulatory; Heart Ventricles; Lidocaine; Propranolol; Tachycardia, Ventricular; Verapamil | 1993 |
Inhibition of Na+/Ca2+ overload with R 56,865 protects against cardiac arrhythmias elicited by ouabain in vivo in guinea-pigs.
Topics: Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Electrocardiography; Guinea Pigs; Heart Rate; Lidocaine; Male; Ouabain; Piperidines; Sodium; Tetrodotoxin; Thiazoles; Verapamil | 1993 |
R56865 is antifibrillatory in reperfused ischemic guinea-pig hearts, even when given only during reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzothiazoles; Calcium; Calcium Channel Blockers; Extracellular Space; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Piperidines; Potassium; Sodium; Thiazoles; Verapamil | 1995 |
Characteristics of slow conduction zone demonstrated during entrainment of idiopathic ventricular tachycardia of left ventricular origin.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Electrocardiography; Electrophysiology; Female; Heart Conduction System; Humans; Lidocaine; Male; Recurrence; Tachycardia, Ventricular; Ventricular Function, Left; Verapamil | 1996 |
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Procainamide; Syndrome; Tachycardia, Ventricular; Verapamil | 1996 |
Idiopathic ventricular fibrillation initiated by a short-coupled ventricular premature beat.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography; Humans; Lidocaine; Male; Propranolol; Ventricular Fibrillation; Verapamil | 1996 |
Ventricular relaxation in the stage 24 chick embryo following changes in volume and blockade of Na+ and Ca2+ channels.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Chick Embryo; Gestational Age; Ion Channel Gating; Isotonic Solutions; Lidocaine; Models, Biological; Ringer's Solution; Sodium Channels; Ventricular Pressure; Verapamil | 1996 |
The effects of verapamil and lidocaine on the duration of propofol and xylazine-ketamine anesthesia in broiler chickens.
Topics: Aging; Analysis of Variance; Anesthesia; Anesthetics; Animals; Calcium Channel Blockers; Chickens; Dose-Response Relationship, Drug; Injections, Intramuscular; Injections, Intravenous; Ketamine; Lidocaine; Male; Propofol; Random Allocation; Sleep; Sodium Channel Blockers; Sodium Channels; Time Factors; Verapamil; Xylazine | 1996 |
Infusions of lidocaine into the amygdala, but not the preoptic area, block pseudopregnancy in the rat.
Topics: Amygdala; Animals; Calcium Channel Blockers; Female; Lidocaine; Male; Preoptic Area; Pseudopregnancy; Rats; Verapamil | 1996 |
Effects of calcium antagonists on binding of local anesthetics to plasma proteins and erythrocytes in mice.
Topics: Anesthetics, Local; Animals; Blood Proteins; Bupivacaine; Calcium Channel Blockers; Diltiazem; Erythrocytes; In Vitro Techniques; Lidocaine; Male; Mice; Nicardipine; Protein Binding; Verapamil | 1996 |
Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Flecainide; Lidocaine; Mexiletine; Models, Biological; Sodium-Potassium-Exchanging ATPase; Swine; Ventricular Fibrillation; Verapamil | 1996 |
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil | 1997 |
Effects of verapamil in ventricular tachycardias. An experimental and clinical study.
Topics: Aconitine; Adult; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Flecainide; Humans; Lidocaine; Tachycardia, Ventricular; Verapamil | 1997 |
Stretch-induced stimulation of lower airway nitric oxide formation in the guinea-pig: inhibition by gadolinium chloride.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Gadolinium; Guinea Pigs; Lidocaine; Lung; Male; Nitric Oxide; Positive-Pressure Respiration; Trimethaphan; Vasodilator Agents; Verapamil | 1997 |
Contrast-medium-induced ventricular fibrillation: arrhythmogenic mechanisms and the role of antiarrhythmic drugs in dogs.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Catheterization; Contrast Media; Coronary Angiography; Coronary Vessels; Dogs; Heart Conduction System; Injections, Intra-Arterial; Iohexol; Lidocaine; Premedication; Propanolamines; Propranolol; Ventricular Fibrillation; Verapamil | 1995 |
Contribution of a voltage-sensitive calcium release mechanism to contraction in cardiac ventricular myocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Guinea Pigs; Heart Ventricles; Lidocaine; Male; Membrane Potentials; Myocardial Contraction; Nifedipine; Ryanodine; Sodium Channel Blockers; Thapsigargin; Time Factors; Verapamil | 1998 |
Physiology of the escape rhythm after radiofrequency atrioventricular junctional ablation.
Topics: Adenosine; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrioventricular Node; Atropine; Bundle-Branch Block; Cardiac Pacing, Artificial; Cardiotonic Agents; Catheter Ablation; Female; Heart Rate; Humans; Isoproterenol; Lidocaine; Male; Verapamil | 1998 |
Tachycardia alone fails to change the myocardial pharmacokinetics and dynamics of lidocaine, thiopental, and verapamil after intravenous bolus administration in sheep.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Coronary Vessels; Female; Heart Rate; Injections, Intravenous; Lidocaine; Myocardial Contraction; Myocardium; Sheep; Tachycardia; Thiopental; Verapamil | 1998 |
Hypotonicity activates a lanthanide-sensitive pathway for K+ release in A6 epithelia.
Topics: Animals; Calcium; Cations; Cell Line; Cell Membrane; Cesium; Epithelial Cells; Gadolinium; Hypotonic Solutions; Kidney; Kinetics; Lanthanum; Lidocaine; Magnesium; Potassium; Potassium Channels; Quinine; Rubidium Radioisotopes; Verapamil | 1998 |
[Correction of the cardiotoxic effect of the anti-arrhythmia agents with befol, sufan, and their combination].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzamides; Benzimidazoles; Cardiotonic Agents; Dibenzazepines; Drug Antagonism; Electrocardiography; Lidocaine; Male; Morpholines; Procainamide; Propranolol; Rats; Rats, Wistar; Succinates; Tryptophan; Verapamil | 1998 |
Ischemia/reperfusion-induced arrhythmias in anaesthetized rats: a role of Na+ and Ca2+ influx.
Topics: Amiloride; Anesthesia; Animals; Arrhythmias, Cardiac; Benzothiazoles; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Heart Rate; Lidocaine; Male; Myocardial Reperfusion Injury; Piperidines; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Sodium Channels; Thiazoles; Verapamil | 1999 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Electrocardiography; Flecainide; Injections; Lidocaine; Piperidines; Pyridines; Sodium Channels; Ventricular Fibrillation; Verapamil | 1999 |
Potassium conductances in isolated single cells from Xenopus laevis colonic epithelium.
Topics: Animals; Barium; Cesium; Colon; Epithelial Cells; Female; Hydrogen-Ion Concentration; Ion Transport; Lidocaine; Membrane Potentials; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Quinidine; Quinine; Tetraethylammonium; Verapamil; Xenopus laevis | 1999 |
The influence of lidocaine and verapamil on haemodynamic parameters after intravenous administration of midazolam in rabbits.
Topics: Anesthetics, Intravenous; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Injections, Intravenous; Lidocaine; Male; Midazolam; Rabbits; Stroke Volume; Vascular Resistance; Verapamil | 1999 |
Effects of antiarrhythmic drugs on the monophasic action potential of the canine isolated, blood-perfused ventricular septum preparation.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Heart Septum; In Vitro Techniques; Lidocaine; Male; Tetrodotoxin; Verapamil | 1998 |
Prolonged perivascular use of verapamil or lidocaine decreases skin flap necrosis.
Topics: Administration, Topical; Animals; Lidocaine; Necrosis; Postoperative Period; Rats; Rats, Sprague-Dawley; Skin Transplantation; Surgical Flaps; Vasoconstriction; Vasodilator Agents; Verapamil | 1999 |
Inhibition of germ tube formation by Candida albicans by local anesthetics: an effect related to ionic channel blockade.
Topics: Amides; Anesthetics, Local; Calcium; Candida albicans; Dose-Response Relationship, Drug; Ion Channels; Lanthanum; Lidocaine; Nifedipine; Ropivacaine; Verapamil | 2000 |
Multiple agents potentiate alpha1-adrenoceptor-induced conduction depression in canine cardiac purkinje fibers.
Topics: Action Potentials; Adrenergic alpha-Agonists; Anesthetics; Animals; Arrhythmias, Cardiac; Dogs; Drug Synergism; Epinephrine; Etomidate; Fatty Acids; Halothane; Heart; In Vitro Techniques; Lidocaine; Neural Conduction; Octanols; Palmitoylcarnitine; Propofol; Purkinje Fibers; Receptors, Adrenergic, alpha-1; Thiopental; Verapamil | 2000 |
[Treatment of cardiac arrhythmia in pregnant women].
Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Arrhythmias, Cardiac; Digoxin; Electric Countershock; Female; Heart Valve Diseases; Humans; Lidocaine; Mitral Valve Prolapse; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Secondary Prevention; Smoking; Smoking Prevention; Verapamil | 2000 |
Onset dynamics of reentrant tachycardia and rate-dependent conduction changes in canine ventricular muscle: effects of Na+ and Ca2+ channel blockade.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Pacing, Artificial; Data Interpretation, Statistical; Dogs; Electrocardiography; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Lidocaine; Sodium Channels; Tachycardia, Ventricular; Verapamil | 2000 |
Effects of verapamil and lidocaine on two components of the re-entry circuit of verapamil-senstitive idiopathic left ventricular tachycardia.
Topics: Adolescent; Adult; Bundle-Branch Block; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Rate; Humans; Infusions, Intravenous; Lidocaine; Male; Purkinje Fibers; Sodium Channels; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ventricular; Verapamil | 2001 |
Influence of ion channels on the proliferation of human chondrocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adult; Aged; Calcium Channel Blockers; Cartilage, Articular; Cell Cycle; Cell Division; Chloride Channels; Chondrocytes; Female; Flow Cytometry; Humans; Ion Channel Gating; Lidocaine; Male; Membrane Potentials; Middle Aged; Osteoarthritis, Knee; Potassium Channel Blockers; Sodium Channel Blockers; Tetraethylammonium; Verapamil | 2002 |
Recognition of fascicular tachycardia in the emergency department.
Topics: Adenosine; Bundle-Branch Block; Calcium Channel Blockers; Drug Resistance; Electrocardiography; Emergencies; Heart Conduction System; Humans; Infant; Lidocaine; Male; Propanolamines; Tachycardia, Ventricular; Verapamil | 2003 |
Verapamil sensitive idiopathic ventricular tachycardia in an infant.
Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Resistance; Drug Therapy, Combination; Electrocardiography; Female; Humans; Infant; Lidocaine; Propranolol; Tachycardia, Ventricular; Verapamil | 2003 |
Contractile effect of acetylcholine on isolated ampullar segment of Fallopian tubes.
Topics: Acetylcholine; Adult; Aged; Diamines; Fallopian Tubes; Female; Follicular Phase; Humans; Lidocaine; Luteal Phase; Mecamylamine; Menopause; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Piperidines; Pirenzepine; Verapamil | 2004 |
The influence of lidocaine and verapamil on the proliferation, CD44 expression and apoptosis behavior of human chondrocytes.
Topics: Apoptosis; Caspase 3; Caspases; Cell Proliferation; Cells, Cultured; Chondrocytes; Female; Humans; Hyaluronan Receptors; Ion Channels; Lidocaine; Middle Aged; Phosphoserine; Thymidine; Verapamil | 2005 |
Pilsicainide-induced verapamil sensitive idiopathic left ventricular tachycardia.
Topics: Adult; Anti-Arrhythmia Agents; Drug Combinations; Electrocardiography; Humans; Lidocaine; Male; Tachycardia, Ventricular; Ventricular Dysfunction, Left; Verapamil | 2006 |
Positive inotropic effect of Murraya koenigii (Linn.) Spreng extract on an isolated perfused frog heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium; Dose-Response Relationship, Drug; Ethanol; Heart; Imidazoles; Lidocaine; Murraya; Myocardium; Phosphodiesterase Inhibitors; Piperazines; Plant Extracts; Propranolol; Purines; Ranidae; Sildenafil Citrate; Sulfones; Theophylline; Vasodilator Agents; Verapamil | 2006 |
Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala.
Topics: Action Potentials; Amygdala; Anesthetics, Local; Animals; Calcium; Calcium Channel Blockers; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; In Vitro Techniques; Lidocaine; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuronal Plasticity; Neurons; Nickel; Patch-Clamp Techniques; Reaction Time; Spider Venoms; Synapses; Verapamil | 2007 |
Effects of antiarrhythmic drugs on apoptotic pathways in H9c2 cardiac cells.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Caspases; Cell Line; Clone Cells; Diploidy; DNA Fragmentation; Dose-Response Relationship, Drug; Lidocaine; Membrane Potentials; Mitochondrial Membranes; Propranolol; Pyrimidinones; Signal Transduction; Time Factors; Verapamil | 2006 |
Effect of sodium and calcium channel blockers on short-term cardiac memory in humans.
Topics: Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Pacing, Artificial; Catheter Ablation; Combined Modality Therapy; Female; Heart; Humans; Lidocaine; Male; Middle Aged; Nitroglycerin; Procainamide; Sodium Channel Blockers; Tachycardia, Supraventricular; Time Factors; Verapamil | 2008 |
Early termination of spiral wave reentry by combined blockade of Na+ and L-type Ca2+ currents in a perfused two-dimensional epicardial layer of rabbit ventricular myocardium.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Rate; Heart Ventricles; Lidocaine; Pericardium; Rabbits; Sodium Channel Blockers; Sodium Channels; Tachycardia, Sinoatrial Nodal Reentry; Treatment Outcome; Verapamil | 2009 |
Mapping ventricular fibrillation: a simplified experimental model leads to a complicated result.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Rate; Heart Ventricles; Lidocaine; Pericardium; Rabbits; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Treatment Outcome; Verapamil | 2009 |
Intralesional injection therapy for Peyronie's disease.
Topics: Anesthetics, Local; Angiogenesis Inhibitors; Humans; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Lidocaine; Male; Penile Induration; Recombinant Proteins; Vasodilator Agents; Verapamil | 2009 |
Comparison of the protective effects of papaverine, lidocaine and verapamil on the sperm quality of the testis after induced torsion-detorsion in rats.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Infertility, Male; Lidocaine; Male; Papaverine; Rats; Rats, Sprague-Dawley; Sperm Count; Sperm Motility; Spermatic Cord Torsion; Spermatozoa; Vasodilator Agents; Verapamil | 2010 |
Genotype-phenotype correlation in tissue models of Brugada syndrome simulating patients with sodium and calcium channelopathies.
Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Anti-Arrhythmia Agents; Body Surface Potential Mapping; Brugada Syndrome; Calcium Channel Blockers; Channelopathies; Dogs; Endocardium; Genotype; Isoproterenol; Lidocaine; Male; Pericardium; Phenotype; Pinacidil; Sodium Channels; Tissue Culture Techniques; Vasodilator Agents; Verapamil | 2010 |
Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cell Line; Dogs; Flunarizine; Humans; Lidocaine; Mice; Myocytes, Cardiac; Phenethylamines; Sulfonamides; Torsades de Pointes; Verapamil | 2010 |
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, Doppler; Female; Humans; Imidazoles; Lidocaine; Linear Models; Male; Middle Aged; Propranolol; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Pressure; Verapamil | 2010 |
Distinct pharmacologic substrate in lidocaine-sensitive, repetitive atrial tachycardia.
Topics: Adenosine; Adult; Aged, 80 and over; Anti-Arrhythmia Agents; Catheter Ablation; Electrocardiography; Electrophysiological Phenomena; Female; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Tachycardia, Ectopic Atrial; Time Factors; Verapamil; Young Adult | 2012 |
[Effect of anti-arrhythmia drugs on mouse arrhythmia induced by Bufonis Venenum].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bufanolides; Electrocardiography; Female; Heart Rate; In Vitro Techniques; Lethal Dose 50; Lidocaine; Male; Mice; Phenytoin; Propranolol; Verapamil | 2011 |
A reappraisal on lidocaine-sensitive repetitive, uniform atrial tachycardia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Catheter Ablation; Combined Modality Therapy; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Retrospective Studies; Tachycardia, Supraventricular; Treatment Outcome; Verapamil | 2013 |
Verapamil-sensitive idiopathic left ventricular tachycardia in a 6-month-old: unique considerations in diagnosis and management in an infant.
Topics: Adenosine; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Female; Heart Ventricles; Humans; Infant; Lidocaine; Procainamide; Tachycardia, Ventricular; Verapamil | 2015 |
Mechano-Pharmacological Characterization of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells.
Topics: Cell Culture Techniques; Cell Differentiation; Humans; Induced Pluripotent Stem Cells; Ion Channels; Lidocaine; Myocardial Contraction; Myocytes, Cardiac; Stress, Mechanical; Verapamil; Veratridine | 2016 |
Characterization of microminipigs as an in vivo experimental model for cardiac safety pharmacology.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiovascular Physiological Phenomena; Electrocardiography; Heart; Heart Rate; Infusions, Intravenous; Lidocaine; Piperidines; Pyridines; Swine; Swine, Miniature; Verapamil | 2017 |
Development of a Next-Generation Biosensing Platform for Simultaneous Detection of Mechano- and Electrophysiology of the Drug-Induced Cardiomyocytes.
Topics: Animals; Astemizole; Biosensing Techniques; Cardiotoxicity; Cardiotoxins; Cells, Cultured; Drug Evaluation, Preclinical; Electric Impedance; Electrophysiological Phenomena; Lidocaine; Microelectrodes; Myocytes, Cardiac; Rats; Verapamil | 2019 |
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS.
Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil | 2019 |
Micro-patterned SU-8 cantilever integrated with metal electrode for enhanced electromechanical stimulation of cardiac cells.
Topics: Animals; Biosensing Techniques; Cardiovascular Agents; Epoxy Compounds; Isoproterenol; Lidocaine; Mechanical Phenomena; Myocytes, Cardiac; Particle Size; Polymers; Surface Properties; Verapamil | 2020 |
Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding.
Topics: Amitriptyline; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Blood Proteins; Dogs; Gene Expression Regulation; Genotype; HIV Protease Inhibitors; Indinavir; Lidocaine; Orosomucoid; Polymorphism, Genetic; Protein Binding; Verapamil | 2021 |
In Vitro Drug Screening Using iPSC-Derived Cardiomyocytes of a Long QT-Syndrome Patient Carrying KCNQ1 & TRPM4 Dual Mutation: An Experimental Personalized Treatment.
Topics: Arrhythmias, Cardiac; Drug Evaluation, Preclinical; Humans; Induced Pluripotent Stem Cells; KCNQ1 Potassium Channel; Lidocaine; Long QT Syndrome; Mutation; Myocytes, Cardiac; Precision Medicine; Quality of Life; TRPM Cation Channels; Verapamil | 2022 |