verapamil and levodopa

verapamil has been researched along with levodopa in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's4 (20.00)18.2507
2000's7 (35.00)29.6817
2010's7 (35.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Kamal, TJ; Molitch, ME1
Andersson, DE; Röjdmark, S; Sundblad, L1
Kamal, TJ; Kelley, SR; Molitch, ME1
Pestana, M; Serrão, MP; Soares-da-Silva, P; Vieira-Coelho, MA1
Gomes, R; Sampaio-Maia, B; Soares-da-Silva, P1
Serrão, MP; Soares-Da-Silva, P1
Hirose, S; Kaneko, S; Okada, M; Yoshida, S; Zhu, G1
Galenko-Yaroshevskii, PA; Kade, AKh; Khvitiya, NG; Kiguradze, MI; Tatulashvili, DR; Turovaya, AY; Uvarov, AE1
Babita, K; Tiwary, AK1
Andreotti, F; Brouwer, MA; Bukowski, P; Conte, M; Gajda, J; Gajda, R; Jasiewicz, M; Kubica, A; Kubica, J; La Torre, G; Lackowski, P; Michalski, P; Navarese, EP; Nowicka, M; Omyła, M; Orsini, N; Piasecki, M; Pietrzykowski, Ł; Pinkas, J; Podhajski, P; Radziwanowski, A; Szymański, P; Urbanowicz, I1

Trials

1 trial(s) available for verapamil and levodopa

ArticleYear
Ion channel inhibition with amiodarone or verapamil in symptomatic hospitalized nonintensive-care COVID-19 patients: The ReCOVery-SIRIO randomized trial.
    Cardiology journal, 2022, Volume: 29, Issue:5

    Topics: Amiodarone; C-Reactive Protein; Carbidopa; COVID-19; Drug Combinations; Humans; Ion Channels; Levodopa; SARS-CoV-2; Verapamil

2022

Other Studies

19 other study(ies) available for verapamil and levodopa

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of calcium channel blockade with verapamil on the prolactin responses to TRH, L-dopa, and bromocriptine.
    The American journal of the medical sciences, 1992, Volume: 304, Issue:5

    Topics: Adult; Bromocriptine; Calcium Channels; Growth Hormone; Humans; Kinetics; Levodopa; Male; Middle Aged; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Time Factors; Verapamil

1992
Calcium and calcium-antagonistic effects on prolactin and growth hormone responses to thyrotropin-releasing hormone and L-dopa in man.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:3

    Topics: Adult; Calcium; Female; Growth Hormone; Humans; Kinetics; Levodopa; Prolactin; Reference Values; Thyrotropin-Releasing Hormone; Verapamil

1981
Mechanism of verapamil calcium channel blockade-induced hyperprolactinemia.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 1

    Topics: Adolescent; Adult; Calcium Channel Blockers; Carbidopa; Dopamine; Female; Humans; Hyperprolactinemia; Levodopa; Male; Middle Aged; Prolactin; Verapamil

1996
Evidence for the involvement of P-glycoprotein on the extrusion of taken up L-DOPA in cyclosporine A treated LLC-PK1 cells.
    British journal of pharmacology, 1998, Volume: 123, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benserazide; Body Water; Calcium Channel Blockers; Cell Survival; Cyclosporine; Decarboxylation; Dopamine; Dopamine Agents; Levodopa; LLC-PK1 Cells; Swine; Verapamil

1998
P-glycoprotein phosphorylation/dephosphorylation and cellular accumulation of L-DOPA in LLC-GA5 Col300 cells.
    Journal of autonomic pharmacology, 1999, Volume: 19, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Humans; Kidney; Levodopa; Okadaic Acid; Phorbols; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Staurosporine; Time Factors; Verapamil

1999
Outward transfer of dopamine precursor L-3,4-dihydroxyphenylalanine (L-dopa) by native and human P-glycoprotein in LLC-PK(1) and LLC-GA5 col300 renal cells.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Line; Dopamine; Fluoresceins; Fluorescent Dyes; Humans; Kidney; Kinetics; Levodopa; LLC-PK1 Cells; Proteins; Rhodamine 123; Swine; Verapamil; Vinblastine

2000
Both 3,4-dihydroxyphenylalanine and dopamine releases are regulated by Ca2+-induced Ca2+ releasing system in rat striatum.
    Neuroscience letters, 2004, May-27, Volume: 362, Issue:3

    Topics: Adenosine; Analysis of Variance; Animals; Calcium; Calcium Channels; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Levodopa; Macrocyclic Compounds; Male; Microdialysis; Oxazoles; Potassium; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Time Factors; Verapamil

2004
Effects of verapamil and amiodarone on sympathoadrenal system and balance of excitatory and inhibitory amino acids in rat medulla oblongata.
    Bulletin of experimental biology and medicine, 2005, Volume: 139, Issue:6

    Topics: Adrenal Glands; Amiodarone; Animals; Calcium Channel Blockers; Dopamine; Epinephrine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Levodopa; Male; Medulla Oblongata; Microinjections; Norepinephrine; Potassium Channel Blockers; Random Allocation; Rats; Rats, Inbred Strains; Serotonin; Sympathetic Nervous System; Verapamil

2005
Skin lipid synthesis inhibition: a possible means for enhancing percutaneous delivery of levodopa.
    Current drug delivery, 2004, Volume: 1, Issue:4

    Topics: Administration, Cutaneous; Animals; Anticholesteremic Agents; Antiparkinson Agents; Atorvastatin; beta-Alanine; Calcium Channel Blockers; Calcium Chloride; Cholesterol; Dose-Response Relationship, Drug; Ethanol; Female; Heptanoic Acids; In Vitro Techniques; Levodopa; Male; Pyrroles; Rats; Rats, Wistar; Serine C-Palmitoyltransferase; Skin; Sphingosine; Time Factors; Verapamil

2004