verapamil and leucine

verapamil has been researched along with leucine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.00)18.7374
1990's10 (40.00)18.2507
2000's6 (24.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Avdeef, A; Tam, KY1
Bellman, K; Knegtel, RM; Settimo, L1
Gottesman, MM; Horio, M; Lovelace, E; Pastan, I1
Hartz, PA; Wilson, PD1
Ikeda, U; Tsuruya, Y; Yaginuma, T1
Ikeda, M; Ikeda, U; Kano, S; Oohara, T; Yaginuma, T1
Harty, RF; Jain, DK; McGuigan, JE1
Cacicedo, L; de los Frailes, MT; Lorenzo, MJ; Sánchez-Franco, F1
Nicholson, RA; Strang, RH; Whitton, PS1
Cahalan, MD; Chandy, KG; DeCoursey, TE; Gupta, S; McLaughlin, C1
Leinweber, KP; Schatz, H1
Cook, DI; Poronnik, P; Tuch, BE; Weinhaus, AJ1
Fadda, GZ; Liou, HH; Massry, SG; Oh, HY; Smogorzewski, M1
Gomolka, D; Handwerger, BS; Peppler, R; Weir, MR1
Abe, A; Kaidoh, K; Kamo, N; Miyauchi, S; Nara, T; Tanabu, S1
Barnett, CR; Flatt, PR; McClenaghan, NH; O'Harte, FP1
Bast, BJ; De Gast, GC; Post, J; Vooijs, WC1
Flatt, PR; McClenaghan, NH1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA1
Guan, YF; Li, GB; Lin, XL; Wu, P; Zhu, CF1
Carpentier, YA; Chardigny, JM; Courtois, P; Louchami, K; Malaisse, WJ; Oguzhan, B; Portois, L; Sener, A; Zhang, Y1
Cai, H; Lash, LH; Putt, DA1
Huo, X; Liu, K; Liu, Q; Ma, X; Meng, Q; Peng, J; Sun, H; Wang, C1
Abdel-Malak, R; Ahearn, GA1

Other Studies

25 other study(ies) available for verapamil and leucine

ArticleYear
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
    Biochimica et biophysica acta, 1991, Jan-09, Volume: 1061, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Biological Transport, Active; Carcinoma, Squamous Cell; Cell Membrane; Dihydropyridines; Drug Resistance; Humans; Kinetics; Leucine; Membrane Glycoproteins; Phenothiazines; Quinidine; Trifluoperazine; Tumor Cells, Cultured; Verapamil; Vinblastine

1991
Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: a role for cysteine proteases.
    Cell biology international reports, 1991, Volume: 15, Issue:12

    Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Humans; Kidney Diseases; Kidney Tubules; Leucine; Microscopy, Fluorescence; Nifedipine; Rabbits; Time Factors; Verapamil

1991
Alpha 1-adrenergic stimulation is coupled to cardiac myocyte hypertrophy.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2

    Topics: Animals; Cells, Cultured; Heart Ventricles; Hypertrophy; Leucine; Myocardium; Norepinephrine; Potassium Chloride; Proto-Oncogene Proteins c-myc; Receptors, Adrenergic, alpha; RNA, Messenger; Verapamil

1991
Mitogenic action of interleukin-1 alpha on vascular smooth muscle cells mediated by PDGF.
    Atherosclerosis, 1990, Volume: 84, Issue:2-3

    Topics: Animals; Antibodies; Aorta; Calcium; Cell Division; Cells, Cultured; DNA; Interleukin-1; Leucine; Male; Mitogens; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Biosynthesis; Rats; Rats, Inbred Strains; Recombinant Proteins; Thymidine; Verapamil

1990
Mechanisms of vasoactive intestinal peptide release in short-term culture of vasoactive intestinal peptide-producing tumor.
    Gastroenterology, 1988, Volume: 94, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Egtazic Acid; Female; Humans; Immunohistochemistry; Leucine; Middle Aged; Pancreatic Neoplasms; Radioimmunoassay; Vasoactive Intestinal Peptide; Verapamil; Vipoma

1988
Divergent effects of acute depolarization on somatostatin release and protein synthesis in cultured fetal and neonatal rat brain cells.
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: Animals; Animals, Newborn; Calcium; Cell Membrane; Cells, Cultured; Cerebral Cortex; Fetus; Kinetics; Leucine; Membrane Potentials; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Rats, Inbred Strains; RNA; Sodium; Somatostatin; Tetrodotoxin; Verapamil; Veratridine

1989
Effect of taurine on calcium accumulation in resting and depolarised insect synaptosomes.
    Journal of neurochemistry, 1988, Volume: 50, Issue:6

    Topics: Animals; Calcium; Calcium Radioisotopes; gamma-Aminobutyric Acid; Grasshoppers; Leucine; Membrane Potentials; Microscopy, Electron; Potassium; Synaptosomes; Taurine; Tetrodotoxin; Verapamil; Veratridine

1988
Voltage-gated potassium channels are required for human T lymphocyte activation.
    The Journal of experimental medicine, 1984, Aug-01, Volume: 160, Issue:2

    Topics: 4-Aminopyridine; Aminopyridines; Cell Line; Diltiazem; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-2; Ion Channels; Kinetics; Leucine; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Phytohemagglutinins; Potassium; Protein Biosynthesis; T-Lymphocytes; Thymidine; Verapamil

1984
Long-term and short-term effects of calcium, verapamil and diazoxide on biosynthesis and release of (pro-) insulin in isolated islets of rat pancreas.
    Acta endocrinologica, 1982, Volume: 99, Issue:1

    Topics: Animals; Calcium; Cells, Cultured; Diazoxide; Insulin; Islets of Langerhans; Leucine; Male; Proinsulin; Rats; Time Factors; Verapamil

1982
Insulin secretagogues, but not glucose, stimulate an increase in [Ca2+]i in the fetal rat beta-cell.
    Diabetes, 1995, Volume: 44, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Calcium; Cells, Cultured; Diazoxide; Female; Fetus; Glipizide; Glucose; Glyceraldehyde; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Pancreas; Rats; Rats, Wistar; Verapamil

1995
Abnormal leucine-induced insulin secretion in chronic renal failure.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Animals; Body Weight; Bridged Bicyclo Compounds; Creatinine; Glutamate Dehydrogenase; Glutaminase; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kidney Failure, Chronic; Kinetics; Leucine; Nephrectomy; Parathyroid Hormone; Parathyroidectomy; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors; Verapamil

1994
Mechanisms responsible for inhibition of lymphocyte activation by agents which block membrane calcium or potassium channels.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 1

    Topics: 4-Aminopyridine; Adult; Calcium; Calcium Channels; Cell Cycle; Cell Survival; Cells, Cultured; DNA Replication; Gene Expression; Humans; Interleukin-2; Leucine; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Potassium Channels; Rubidium; Stereoisomerism; Thymidine; Uridine; Verapamil

1993
Rhodamine 123 efflux transporter in Haloferax volcanii is induced when cultured under 'metabolic stress' by amino acids: the efflux system resembles that in a doxorubicin-resistant mutant.
    The Biochemical journal, 1996, Feb-15, Volume: 314 ( Pt 1)

    Topics: Adenosine Triphosphate; Amino Acids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Culture Media; Dicyclohexylcarbodiimide; Doxorubicin; Drug Resistance, Microbial; Halobacteriaceae; Leucine; Membrane Potentials; Rhodamine 123; Rhodamines; Verapamil

1996
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
    The Journal of endocrinology, 1996, Volume: 151, Issue:3

    Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil

1996
Efficacy of an anti-CD138 immunotoxin and doxorubicin on drug-resistant and drug-sensitive myeloma cells.
    International journal of cancer, 1999, Nov-12, Volume: 83, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Survival; DNA; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Humans; Immunotoxins; Leucine; Membrane Glycoproteins; Multiple Myeloma; Protein Biosynthesis; Proteoglycans; Syndecan-1; Syndecans; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil

1999
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
    Pancreas, 2000, Volume: 20, Issue:1

    Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil

2000
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
    The Journal of endocrinology, 2000, Volume: 167, Issue:3

    Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil

2000
[Enantioseparation of twelve pharmaceutical racemates with high performance capillary electrophoresis using L-leucine as chiral selector].
    Se pu = Chinese journal of chromatography, 2001, Volume: 19, Issue:2

    Topics: Electrophoresis, Capillary; Fenfluramine; Leucine; Mexiletine; Pharmaceutical Preparations; Silicon Dioxide; Stereoisomerism; Verapamil

2001
Pancreatic islet function in omega3 fatty acid-depleted rats: Glucose metabolism and nutrient-stimulated insulin release.
    Endocrine, 2006, Volume: 29, Issue:3

    Topics: Animals; Blood Glucose; Carbon Dioxide; Diet; Dietary Fats; Fats; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Liver; Male; Phospholipids; Rats; Triglycerides; Verapamil

2006
Membrane transport function in primary cultures of human proximal tubular cells.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blotting, Western; Calcium Channel Blockers; Cation Transport Proteins; Cell Membrane; Cells, Cultured; Female; Humans; Immunohistochemistry; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Leucine; Male; Microvilli; Middle Aged; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Symporters; Verapamil

2006
Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Nov-20, Volume: 50, Issue:3-4

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; CD13 Antigens; Cell Proliferation; Cyclosporine; Dogs; Humans; Immunologic Factors; Intestinal Absorption; Intestinal Mucosa; Intestines; K562 Cells; Leucine; Madin Darby Canine Kidney Cells; Male; Rats, Wistar; U937 Cells; Verapamil

2013
Regulation of transmural transport of amino acid/metal conjugates by dietary calcium in crustacean digestive tract.
    Journal of experimental zoology. Part A, Ecological genetics and physiology, 2014, Volume: 321, Issue:3

    Topics: Animals; Biological Transport; Calcium, Dietary; Gastrointestinal Tract; Leucine; Male; Manganese; Models, Biological; Molecular Mimicry; Nephropidae; Tritium; Verapamil

2014