verapamil and labetalol

verapamil has been researched along with labetalol in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199014 (33.33)18.7374
1990's2 (4.76)18.2507
2000's9 (21.43)29.6817
2010's16 (38.10)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Akamatsu, M1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Chavatte, P; Dubois, J; Farce, A; Furman, C; Gilleron, P; Hénichart, JP; Le Broc-Ryckewaert, D; Lemoine, A; Millet, R; Pommery, N; Wlodarczyk, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alam, MA; Drewes, LR; Gurrapu, S; Jonnalagadda, SK; Lueth, EA; Mereddy, VR; Nelson, GL; Ronayne, CT; Solano, LN1
Abouf, M; Abutaleb, NS; Chen, L; Elsebaei, MM; Ghiaty, A; Hegazy, YA; Malwal, SR; Mayhoub, AS; Mohammad, H; Oldfield, E; Seleem, MN; Zhang, J1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R1
Nencini, P1
Danis, M; Dukes, GE; Hak, LJ; Han, YH; Hermann, DJ; Hussey, EK; Krol, TF; Powell, JR1
Louis, WJ; Rand, MJ; Story, DF; Tung, LH1
Fruncillo, RA; Lener, ME; Rocci, ML; Sirgo, MA; Vlasses, PH1
Littler, WA; Smith, SA1
Li, CH; Liu, GM; Niu, SY; Ying, SD1
Cubeddu, LX; Halperin, AK1
Anavekar, SN; Doyle, AE1
Barton, JR; Freeman, JG; Record, CO1
Anand, MP1
Adam, WR; Anavekar, SN; Barter, C; Doyle, AE1
Lowenthal, DT1
Angelini, A; Dario, C; Mazzucato, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Vescovo, G1
Doyle, AE1
Bar-Andziak, E; Chlewicka, I1
Allen, LV; Erickson, MA1
Amidon, GL; Incecayir, T; Tsume, Y1
Badaoui, M; Dickson, CJ; Hornak, V; Kells, A; Molteni, C; Rosta, E1

Reviews

5 review(s) available for verapamil and labetalol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antihypertensive agents--the race for third place.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil

1985
The role of calcium channel blockers in the treatment of hypertension.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil

1986
Hypertension--drug management.
    The Journal of the Association of Physicians of India, 1982, Volume: 30, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diazoxide; Humans; Hypertension; Indoramin; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Prazosin; Sympatholytics; Vasodilator Agents; Verapamil

1982
Hypertension and calcium antagonists.
    Clinical and experimental pharmacology & physiology. Supplement, 1982, Volume: 6

    Topics: Airway Resistance; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Labetalol; Pindolol; Propranolol; Verapamil

1982

Trials

6 trial(s) available for verapamil and labetalol

ArticleYear
Comparison of verapamil, diltiazem, and labetalol on the bioavailability and metabolism of imipramine.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Antidepressive Agents, Tricyclic; Biological Availability; Desipramine; Diltiazem; Drug Administration Schedule; Drug Interactions; Humans; Imipramine; Labetalol; Male; Verapamil

1992
Comparative evaluation of the effects of labetalol, verapamil and diltiazem on antipyrine and indocyanine green clearances.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:10

    Topics: Adult; Antipyrine; Diltiazem; Half-Life; Humans; Indocyanine Green; Labetalol; Male; Random Allocation; Verapamil

1989
The role of calcium channel blockers in the treatment of hypertension.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil

1986
Evaluation of verapamil in the treatment of hypertension.
    Journal of clinical hypertension, 1986, Volume: 2, Issue:3 Suppl

    Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Middle Aged; Pindolol; Random Allocation; Sodium Chloride Symporter Inhibitors; Verapamil

1986
Effect of isosorbide dinitrate, verapamil, and labetalol on portal pressure in cirrhosis.
    British medical journal (Clinical research ed.), 1985, Aug-31, Volume: 291, Issue:6495

    Topics: Humans; Hypertension, Portal; Isosorbide Dinitrate; Labetalol; Liver Cirrhosis; Venous Pressure; Verapamil

1985
A double-blind comparison of verapamil and labetalol in hypertensive patients with coexisting chronic obstructive airways disease.
    Journal of cardiovascular pharmacology, 1982, Volume: 4 Suppl 3

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Middle Aged; Pulse; Respiratory Function Tests; Verapamil

1982

Other Studies

32 other study(ies) available for verapamil and labetalol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.
    Journal of medicinal chemistry, 2011, Mar-10, Volume: 54, Issue:5

    Topics: Androgen Antagonists; Azepines; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Farnesyltranstransferase; Humans; Hydrophobic and Hydrophilic Interactions; Male; Models, Molecular; Prostatic Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents.
    Bioorganic & medicinal chemistry letters, 2016, 07-15, Volume: 26, Issue:14

    Topics: Animals; Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Monocarboxylic Acid Transporters; Structure-Activity Relationship; Symporters

2016
Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA).
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Alkynes; Animals; Anti-Bacterial Agents; Half-Life; Methicillin-Resistant Staphylococcus aureus; Mice; Microsomes, Liver; Staphylococcal Infections; Thiazoles

2018
Development of an
    Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic

2021
The influence of calcium on the antilipolytic action of propranolol, timolol, labetalol, verapamil, procaine, and papaverine in rat adipocytes.
    Pharmacological research communications, 1979, Volume: 11, Issue:9

    Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium; In Vitro Techniques; Isoproterenol; Labetalol; Lipolysis; Male; Papaverine; Procaine; Propranolol; Rats; Timolol; Vasodilator Agents; Verapamil

1979
Cardiac alpha-adrenoceptors: postjunctional and prejunctional.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Calcium; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; Idazoxan; In Vitro Techniques; Labetalol; Methoxamine; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical; Verapamil

1986
Hemodynamic effects of hypotension induced by verapamil or labetalol in dogs.
    Chinese medical journal, 1988, Volume: 101, Issue:2

    Topics: Animals; Dogs; Hemodynamics; Hypotension; Labetalol; Verapamil

1988
New drugs for hypertension.
    American family physician, 1984, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Bumetanide; Diltiazem; Dipeptides; Enalapril; Guanabenz; Guanidines; Humans; Indapamide; Labetalol; Nifedipine; Pindolol; Verapamil

1984
[Evaluation of the efficacy of various hypotensive drugs in broad-breasted white turkeys as an experimental model of arterial hypertension with high catecholamine levels].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Sep-30, Volume: 59, Issue:9

    Topics: Animals; Antihypertensive Agents; Captopril; Catecholamines; Disease Models, Animal; Furosemide; Hypertension; Labetalol; Male; Oxprenolol; Rats; Turkeys; Verapamil

1983
[New hypotensive drugs].
    Kardiologia polska, 1981, Volume: 24, Issue:10

    Topics: Antihypertensive Agents; Captopril; Drug Evaluation; Guanfacine; Guanidines; Humans; Hypertension; Labetalol; Minoxidil; Nifedipine; Phenylacetates; Saralasin; Verapamil

1981
Stability of labetalol hydrochloride, metoprolol tartrate, verapamil hydrochloride, and spironolactone with hydrochlorothiazide in extemporaneously compounded oral liquids.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Oct-01, Volume: 53, Issue:19

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diuretics; Dosage Forms; Drug Compounding; Drug Stability; Humans; Hydrochlorothiazide; Labetalol; Metoprolol; Sodium Chloride Symporter Inhibitors; Spironolactone; Suspensions; Verapamil

1996
Comparison of the permeability of metoprolol and labetalol in rat, mouse, and Caco-2 cells: use as a reference standard for BCS classification.
    Molecular pharmaceutics, 2013, Mar-04, Volume: 10, Issue:3

    Topics: Animals; Biological Transport; Caco-2 Cells; Humans; Ileum; Jejunum; Labetalol; Metoprolol; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Verapamil

2013
Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
    The journal of physical chemistry. B, 2018, 12-13, Volume: 122, Issue:49

    Topics: Cell Membrane Permeability; Chlorpromazine; Desipramine; Domperidone; Kinetics; Labetalol; Lipid Bilayers; Loperamide; Molecular Dynamics Simulation; Molecular Structure; Propranolol; Thermodynamics; Verapamil

2018