Compounds > verapamil

verapamil and l 660,711

verapamil has been researched along with l 660,711 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H1
Chen, ZS; Kruh, GD; Kuwano, M; Lee, K; Raftogianis, RB; Walther, S; Zeng, H1
Borchardt, RT; Horie, K; Tang, F1
Honda, Y; Koyabu, N; Kuwano, M; Morimoto, S; Ohtani, H; Sawada, Y; Shoyama, Y; Uchiumi, T; Ushigome, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chan, KF; Chan, TH; Chow, LM; Lam, CY; Tsang, KH; Wong, IL; Zhao, Y1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Adlere, I; Andzans, Z; Domracheva, I; Duburs, G; Grinberga, S; Krasnova, L; Krauze, A; Shestakova, I; Sokolova, E1
Chen, ZS; Gupta, P; Lei, ZN; Li, YN; Li, ZH; Liu, HM; Liu, Y; Ma, LY; Wang, B; Wang, JQ; Zhang, XH; Zhao, B; Zhao, YD1
Chan, KF; Chan, TH; Chow, LMC; Hu, X; Law, MC; Lo, AMY; Wong, ILK; Zhu, X1
Chen, XY; Chen, ZS; Dong, Y; Li, X; Liu, G; Ma, Y; Pei, Y; Qian, H; Qiu, Q; Shi, W; Si, G; Wei, X; Ye, J; Yin, D; Zou, F1

Other Studies

13 other study(ies) available for verapamil and l 660,711

ArticleYear
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.
    Cancer research, 2001, Oct-01, Volume: 61, Issue:19

    Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium

2001
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
    Cancer research, 2002, Jun-01, Volume: 62, Issue:11

    Topics: Animals; Antimetabolites, Antineoplastic; Baculoviridae; Carrier Proteins; Cell Line; Folate Receptors, GPI-Anchored; Folic Acid; Insecta; Liposomes; LLC-PK1 Cells; Methotrexate; Multidrug Resistance-Associated Proteins; Osmosis; Polyglutamic Acid; Receptors, Cell Surface; Swine; Transfection

2002
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?
    Pharmaceutical research, 2002, Volume: 19, Issue:6

    Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine

2002
Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux.
    British journal of pharmacology, 2004, Volume: 143, Issue:7

    Topics: Algorithms; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Beverages; Biological Transport, Active; Caco-2 Cells; Calcium Channel Blockers; Citrus; Cyclosporine; Food-Drug Interactions; HIV Protease Inhibitors; Humans; Immunosuppressive Agents; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Plant Extracts; Propionates; Quinolines; Saquinavir; Transfection; Verapamil; Vinblastine

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.
    Journal of medicinal chemistry, 2009, Sep-10, Volume: 52, Issue:17

    Topics: Apigenin; Binding, Competitive; Cell Line, Tumor; Dimerization; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; Hydroxides; Intracellular Space; Multidrug Resistance-Associated Proteins; Structure-Activity Relationship

2009
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Thieno[2,3-b]pyridines--a new class of multidrug resistance (MDR) modulators.
    Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Cell Survival; Drug Resistance, Multiple; Humans; Mice; Multidrug Resistance-Associated Proteins; Muscle, Smooth; Neoplasm Proteins; NIH 3T3 Cells; Protein Binding; Rats; Structure-Activity Relationship; Thienopyridines

2014
Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance.
    Journal of medicinal chemistry, 2018, Jul-26, Volume: 61, Issue:14

    Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Multiple; Gene Expression Regulation, Neoplastic; Humans; Intracellular Space; Models, Molecular; Molecular Docking Simulation; Protein Conformation; Protein Transport; Pyrimidines; Urea

2018
Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".
    Journal of medicinal chemistry, 2018, 11-21, Volume: 61, Issue:22

    Topics: Alkynes; Animals; Antineoplastic Agents; Azides; Cell Line, Tumor; Click Chemistry; Dimerization; Doxorubicin; Drug Design; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Female; Flavonoids; Humans; Intracellular Space; Mice; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Protein Conformation

2018
Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue.
    Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Discovery; Drug Resistance, Multiple; Humans; Isoquinolines; K562 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Pyridines; Pyrroles; Smad3 Protein; Xenograft Model Antitumor Assays

2020