verapamil and ko 143

verapamil has been researched along with ko 143 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Hegedus, T; Kéri, G; Német, K; Orfi, L; Ozvegy-Laczka, C; Sarkadi, B; Schuetz, JD; Ujhelly, O; Váradi, A; Várady, G1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Müller, H; Pick, A; Wiese, M1
Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M1
Chan, KF; Chan, TH; Chow, LM; Kan, JW; Wong, IL; Yan, CS1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chow, LM; Jiang, T; Liu, T; Wan Sheng, B; Wang, SW; Wen, BJ; Wong, IL; Yuan, J1
Biao, WS; Bin, JW; Chow, LM; Hu, X; Jiang, T; Wong, IL; Xing, LF; Yu, ZX1
Chow, LM; Duan, LX; Hu, X; Jiang, T; Li, XM; Liu, T; Liu, Z; Wan, SB; Wang, BC; Wong, IL; Yuan, J; Zhang, XY1
Baubichon-Cortay, H; Falson, P; Ferreira, MU; Khonkarn, R; Madeira Girio, P; Moreno, A; Mulhovo, S; Paterna, A1
Chen, XY; Chen, ZS; Dong, Y; Li, X; Liu, G; Ma, Y; Pei, Y; Qian, H; Qiu, Q; Shi, W; Si, G; Wei, X; Ye, J; Yin, D; Zou, F1
Cai, Z; Ghaleb, H; Huang, W; Jiang, Y; Liu, Y; Qian, H; Qiu, Q; Shi, W; Yin, Z; Zhang, P; Zhou, J; Zou, F1

Other Studies

12 other study(ies) available for verapamil and ko 143

ArticleYear
High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.
    Molecular pharmacology, 2004, Volume: 65, Issue:6

    Topics: Adenosine Triphosphatases; Animals; Cell Line; Cell Membrane; Drug Resistance, Multiple; Enzyme Inhibitors; HL-60 Cells; Humans; Insecta; Protein-Tyrosine Kinases

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
    Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured

2008
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship

2011
Amine linked flavonoid dimers as modulators for P-glycoprotein-based multidrug resistance: structure-activity relationship and mechanism of modulation.
    Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5

    Topics: Adenosine Triphosphatases; Amines; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzylamines; Cell Line, Tumor; Dimerization; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flavones; Flavonoids; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Paclitaxel; Polyethylene Glycols; Solubility; Structure-Activity Relationship

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells.
    European journal of medicinal chemistry, 2012, Volume: 54

    Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Resistance, Multiple; Humans; Methylation; Mice; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Quercetin

2012
Structure-activity relationship study of permethyl ningalin B analogues as P-glycoprotein chemosensitizers.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Heterocyclic Compounds, 3-Ring; Humans; Intracellular Space; Models, Molecular; Molecular Conformation; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Paclitaxel; Safety; Structure-Activity Relationship

2013
Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.
    Journal of medicinal chemistry, 2015, Jun-11, Volume: 58, Issue:11

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Catechin; Cell Proliferation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonols; Humans; Methylation; Models, Molecular; Molecular Structure; Neoplasm Proteins; Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2015
Monoterpene indole alkaloid azine derivatives as MDR reversal agents.
    Bioorganic & medicinal chemistry, 2018, 01-15, Volume: 26, Issue:2

    Topics: Alkaloids; Animals; Cell Line; Cell Proliferation; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Hydrazines; Indoles; Mice; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship

2018
Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue.
    Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Discovery; Drug Resistance, Multiple; Humans; Isoquinolines; K562 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Docking Simulation; Pyridines; Pyrroles; Smad3 Protein; Xenograft Model Antitumor Assays

2020
Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel

2022