verapamil and ketanserin

verapamil has been researched along with ketanserin in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19909 (29.03)18.7374
1990's14 (45.16)18.2507
2000's2 (6.45)29.6817
2010's5 (16.13)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, Y; Feng, F; He, S; Li, Q; Liao, Q; Liu, W; Liu, Y; Lu, W; Sun, H; Xing, S; Xiong, B; Yang, H1
Mustafa, AA1
Pillai, G; Sutter, MC1
Appell, KC; Barrett, RJ; Kilpatrick, BF; Nolan, JC; Proakis, AG; Walsh, DA1
Beubler, E; Hinterleitner, T; Horina, G1
Beubler, E; Bukhave, K; Kollar, G; Rask-Madsen, J; Saria, A1
Masuyama, Y; Nishio, I; Tsuda, K1
Hofmann, HP; Raschack, M; Unger, L1
Jaffe, BM; Kimura, K; LaRosa, CA; Money, SR; Pimpl, W; Sherlock, D1
Andersson, TL; Larsson, B; Vinge, E1
Cerini, R; Hadengue, A; Koshy, A; Lebrec, D; Lee, SS; Moreau, R1
Affolter, H; Burkard, WP; Pletscher, A1
Olesen, SP1
Adachi, H; Shoji, T1
Kirchengast, M; Lehmann, HD; Rübsamen, K1
Boulanger, CM; Kirchengast, M; Park, SJ; Vanhoutte, PM1
Marwood, JF; Okoro, EO; Stokes, GS1
López-Novoa, JM; Montero, A; Reverte, M; Rodríguez-López, A1
Allegra, A; Aloisi, C; Baldari, S; Buemi, M; Imbesi, D; Laganà, A; Morabito, N; Palella, S; Privitera, M; Villari, C1
Nagatomo, T; Shibata, A; Shimada, K; Tsuchihashi, H; Wakabayashi, H; Watanabe, K1
Nagatomo, T; Sasaki, K; Shibata, A; Shimada, K; Wakabayashi, H; Watanabe, K1
Beaughard, M; Brasset, M; John, G; Massingham, R1
Marwood, JF; Okoro, EO1
Borda, E; Busch, L; Wald, M1

Trials

1 trial(s) available for verapamil and ketanserin

ArticleYear
Is erythropoietin-induced hypertension a phenomenon due to the intracellular Ca++ mobilisation?
    International angiology : a journal of the International Union of Angiology, 1994, Volume: 13, Issue:1

    Topics: Adult; Blood Circulation; Calcium; Erythropoietin; Gallopamil; Humans; Ketanserin; Male; Nifedipine; Recombinant Proteins; Vasoconstrictor Agents; Verapamil

1994

Other Studies

30 other study(ies) available for verapamil and ketanserin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery and Biological Evaluation of a Novel Highly Potent Selective Butyrylcholinsterase Inhibitor.
    Journal of medicinal chemistry, 2020, 09-10, Volume: 63, Issue:17

    Topics: Aminoquinolines; Animals; Benzimidazoles; Butyrylcholinesterase; Cell Line, Tumor; Cholinesterase Inhibitors; Drug Discovery; Drug Evaluation, Preclinical; Female; Humans; Male; Mice, Inbred ICR; Microsomes, Liver; Molecular Docking Simulation; Molecular Dynamics Simulation; Neuroprotective Agents; Protein Binding; Small Molecule Libraries

2020
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
    Neuropharmacology, 1991, Volume: 30, Issue:8

    Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil

1991
Effect of human plasma proteins on spontaneous contractile activity of rat mesenteric portal vein.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:6

    Topics: Alpha-Globulins; Animals; Atropine; Beta-Globulins; Blood Proteins; Chlorpheniramine; gamma-Globulins; Humans; Immunoglobulin G; Ketanserin; Male; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Portal Vein; Rats; Rats, Inbred Strains; Saralasin; Serum Albumin; Verapamil

1990
AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Animals; Atrial Function; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; Diuresis; Dose-Response Relationship, Drug; Edema; Guinea Pigs; Heart Atria; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nimodipine; Piperidines; Platelet Aggregation; Propiophenones; Rabbits; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Histamine H1; Receptors, Serotonin; Reflex; Serotonin; Serotonin Antagonists; Tritium; Verapamil

1991
Protein kinase C and intestinal fluid secretion: involvement of prostaglandin E2 but not of 5-hydroxytryptamine.
    European journal of pharmacology, 1990, Jul-17, Volume: 182, Issue:3

    Topics: Animals; Body Fluids; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Indomethacin; Intestinal Mucosa; Jejunum; Ketanserin; Protein Kinase C; Rats; Rats, Inbred Strains; Serotonin; Tetradecanoylphorbol Acetate; Verapamil

1990
Involvement of 5-hydroxytryptamine, prostaglandin E2, and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo.
    Gastroenterology, 1989, Volume: 96, Issue:2 Pt 1

    Topics: Animals; Body Fluids; Cholera Toxin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Indomethacin; Intestine, Small; Ketanserin; Nifedipine; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Verapamil

1989
Effects of ketanserin, verapamil and diltiazem on vascular sympathetic nerve activity in hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1989, Volume: 11 Suppl 1

    Topics: Animals; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Ketanserin; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Verapamil

1989
(S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. 1st communication: pharmacological profile.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:3

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Guinea Pigs; In Vitro Techniques; Ischemic Attack, Transient; Ketanserin; Male; Membranes; Mice; Muscle, Smooth, Vascular; Muscles; Myocardial Contraction; Rats; Rats, Inbred Strains; Serotonin Antagonists; Verapamil

1989
The role of serotonin in the canine secretory response to cholera toxin in vivo.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: Animals; Body Water; Cholera Toxin; Dogs; Electrolytes; Intestinal Secretions; Ketanserin; Serotonin; Verapamil

1989
Effects of some calcium antagonists on aggregation by adrenalin and serotonin and on alpha-adrenoceptor radioligand binding in human platelets.
    Acta physiologica Scandinavica, 1988, Volume: 133, Issue:3

    Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Diltiazem; Epinephrine; Humans; Ketanserin; Nifedipine; Phentolamine; Platelet Aggregation; Radioligand Assay; Serotonin; Verapamil; Yohimbine

1988
Combination of ketanserin and verapamil or propranolol in patients with alcoholic cirrhosis: search for an additive effect.
    Hepatology (Baltimore, Md.), 1989, Volume: 9, Issue:1

    Topics: Drug Synergism; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension, Portal; Ketanserin; Liver Cirrhosis, Alcoholic; Propranolol; Splanchnic Circulation; Time Factors; Verapamil

1989
Verapamil, an antagonist at 5-hydroxytryptamine receptors of human blood platelets.
    European journal of pharmacology, 1985, Jan-22, Volume: 108, Issue:2

    Topics: Adenosine Diphosphate; Binding, Competitive; Blood Platelets; Cerebral Cortex; Gallopamil; Humans; In Vitro Techniques; Ketanserin; Membranes; Piperidines; Receptors, Serotonin; Spiperone; Verapamil

1985
A calcium-dependent reversible permeability increase in microvessels in frog brain, induced by serotonin.
    The Journal of physiology, 1985, Volume: 361

    Topics: Animals; Blood-Brain Barrier; Brain; Calcium; Capillary Permeability; Dose-Response Relationship, Drug; Electric Conductivity; Endothelium; Ketanserin; Piperidines; Rana temporaria; Serotonin; Serotonin Antagonists; Verapamil

1985
Characteristics of the inhibition of ligand binding to serotonin receptors in rat brain membranes by verapamil.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:4

    Topics: Animals; Binding, Competitive; In Vitro Techniques; Ketanserin; Male; Membranes; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Verapamil

1986
Inhibition by the combined Ca2+ and 5-HT2 receptor antagonist nexopamil (LU 49938) of intracoronary thrombus formation in a canine model of arterial stenosis and intimal damage.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:5

    Topics: Animals; Calcium; Coronary Circulation; Coronary Thrombosis; Dogs; Female; Gallopamil; Hemodynamics; Injections, Intravenous; Ketanserin; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin Antagonists; Verapamil

1993
Effects of the combined 5-hydroxytryptamine2 receptor and Ca2+ channel antagonist LU49938 on the responsiveness of isolated porcine coronary arteries with and without endothelium.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:3

    Topics: Analysis of Variance; Animals; Calcium-Binding Proteins; Coronary Vessels; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Serotonin; Serotonin Antagonists; Swine; Verapamil

1994
Interaction between Ca2+, verapamil, and ketanserin in rat tail artery and aorta.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:4

    Topics: Animals; Aorta, Thoracic; Arteries; Calcium; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Serotonin; Serotonin Antagonists; Tail; Verapamil

1995
The effect of LU-49938 (nexopamil) on the activation by serotonin of mesangial cells.
    Fundamental & clinical pharmacology, 1995, Volume: 9, Issue:2

    Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Glomerular Mesangium; Ketanserin; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Thymidine; Time Factors; Verapamil

1995
Alterations of binding characteristics of alpha 1-,beta 1-adrenoceptors and Ca2+ binding sites in the myocardium of spontaneously hypertensive rats (SHR) by chronically administered bunazosin, atenolol, ketanserin and verapamil.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Atenolol; Binding Sites; Blood Pressure; Calcium Channels; Heart; In Vitro Techniques; Ketanserin; Kinetics; Myocardium; Norepinephrine; Quinazolines; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Verapamil

1993
Cardiomyopathic hamster hearts: long-term effects of drugs on catecholamine contents and binding characteristics of alpha 1- and beta 1-adrenergic receptors.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathies; Catecholamines; Cricetinae; Heart; Ketanserin; Mesocricetus; Myocardium; Propanolamines; Radioligand Assay; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Verapamil; Xamoterol

1993
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Animals; Aspirin; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart Block; Infusions, Intravenous; Ketanserin; Male; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Vasodilator Agents; Verapamil

1995
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997
Long-term treatment with fluoxetine associates with peripheral effects on rat vas deferens contractility.
    Life sciences, 1999, Volume: 64, Issue:10

    Topics: Adrenergic Agents; Animals; Antidepressive Agents, Second-Generation; Binding Sites; Calcium; Cyclooxygenase Inhibitors; Fluoxetine; Indomethacin; Isoproterenol; Ketanserin; Male; Muscle Contraction; Nitroprusside; Norepinephrine; Prazosin; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Vas Deferens; Verapamil

1999