Compounds > verapamil

verapamil and jq1 compound

verapamil has been researched along with jq1 compound in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Albert, DH; Bui, MH; Edalji, RP; Elmore, SW; Faivre, EJ; Fang, G; Fidanze, SD; Gao, W; Hasvold, LA; Huang, X; Hutchins, CW; Kati, WM; Li, L; Lin, X; Liu, D; Magoc, TJ; Mantei, RA; Martin, R; McDaniel, KF; Park, CH; Pratt, JK; Rajaraman, G; Shen, JJ; Shen, Y; Sheppard, GS; Soltwedel, T; Sun, CC; Wang, L; Wang, R; Warder, SE; Wilcox, D; Wong, S1
Biggin, PC; Bluck, JP; Bruno, PA; Clayton, J; Conway, SJ; Evans, CNG; Filippakopoulos, P; Guzanov, P; Hammond, EM; Hewings, DS; Hicks, A; Humphreys, PG; Jennings, LE; Laurin, CMC; Mapp, AK; Mistry, IN; Moroglu, M; Picaud, S; Reynolds, JK; Schiedel, M; Scorah, AR; See, L; Stazi, G1
Dubrovskyi, O; Dye, K; Gutgesell, LM; Huang, F; Li, Y; Ratia, K; Shen, Z; Thatcher, GRJ; Tonetti, DA; Xiong, R; Zhao, H; Zhao, J1

Other Studies

4 other study(ies) available for verapamil and jq1 compound

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.
    Journal of medicinal chemistry, 2017, 10-26, Volume: 60, Issue:20

    Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Discovery; Fluorescence Resonance Energy Transfer; Half-Life; Humans; Mass Spectrometry; Mice; Proteins; Proton Magnetic Resonance Spectroscopy; Pyridones; Structure-Activity Relationship; Sulfonamides

2017
BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.
    Bioorganic & medicinal chemistry, 2018, 07-15, Volume: 26, Issue:11

    Topics: Biological Assay; Blotting, Western; Cell Cycle Proteins; Crystallography, X-Ray; Drug Stability; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Ligands; Luciferases; MCF-7 Cells; Molecular Dynamics Simulation; Molecular Structure; Nuclear Proteins; Structure-Activity Relationship; Transcription Factors

2018
Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib.
    Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13

    Topics: Animals; Breast Neoplasms; Drug Resistance, Neoplasm; Fulvestrant; Humans; MCF-7 Cells; Mice; Models, Molecular; Piperazines; Protein Domains; Pyridines; Pyridones; Receptors, Estrogen; Tissue Distribution; Transcription Factors; Xenograft Model Antitumor Assays

2020