verapamil has been researched along with isoniazid in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.11) | 18.2507 |
| 2000's | 8 (21.62) | 29.6817 |
| 2010's | 22 (59.46) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bucar, F; Gröblacher, B; Kunert, O | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Alam, MZ; Bruhn, DF; Feng, L; Hurdle, JG; Lee, RB; Lee, RE; Maddox, MM; Narula, G; Sandhaus, S; Simmons, CJ; Sun, D; Tse-Dinh, YC; Tsutsumi, LS; Wu, X | 1 |
| Dixit, PP; Thore, SN | 1 |
| Bhakta, S; Brown, AK; Castagnolo, D; Dasugari, S; Evangelopoulos, D; Maitra, A; Manetti, F; McHugh, TD; Mortazavi, PN; Petricci, E; Scalacci, N; Twist, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hemmer, M; Hilgeroth, A; Lentz, F; Reiling, N | 1 |
| Azzali, E; Cabassi, CS; Costantino, G; Flisi, S; Kaushik, A; Lamichhane, G; Machado, D; Pieroni, M; Vacondio, F; Viveiros, M | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Eslamimehr, S; Franzblau, SG; Kong, Y; Kurosu, M; Lemieux, MR; Mitachi, K; Park, F; Pressly, JD; Siricilla, S; Wang, Y; Yang, D | 1 |
| Ang, CW; Avery, VM; Blaskovich, MAT; Butler, MS; Cooper, MA; Debnath, A; Hahn, HJ; Jarrad, AM; Jones, AJ; Karoli, T; Pelingon, R; Sykes, ML; Tan, L; West, NP; Woods, K | 1 |
| Ang, CW; Avery, VM; Bernhardt, PV; Blaskovich, MAT; Bolisetti, R; Cooper, MA; Francisco, AF; Franzblau, SG; Hinton, AO; Jackson, CJ; Kelly, JM; Lee, BM; Sykes, ML; Tan, L; Wang, Y; West, NP | 1 |
| Vidrio, H | 1 |
| Gangadharam, P; Gollapudi, S; Gupta, S; Reddy, M; Tsuruo, T | 1 |
| Chakrabarti, P; Choudhuri, BS; Sen, S | 1 |
| Amaral, L; Bettencourt, R; Jordaan, AM; Leandro, C; Ordway, D; Portugal, I; Victor, TC; Viveiros, M | 1 |
| Medina, M; Vidrio, H | 1 |
| Amaral, L; Baptista, P; Couto, I; Machado, D; Perdigão, J; Portugal, I; Rodrigues, L; Veigas, B; Viveiros, M | 1 |
| Aínsa, JA; Bailo, R; Rodrigues, L; Villellas, C; Viveiros, M | 1 |
| Abate, G; Campbell, M; Chibale, K; Eickhoff, CS; Hamzabegovic, F; Hoft, DF; Kumar, M; Ruminiski, PG; Selimovic, A; Singh, K | 1 |
| Abbasova, K; Anshakova, A; Baklaushev, V; Balabanyan, V; Chekhonin, V; Gelperina, S; Kreuter, J; Maksimenko, O; Malinovskaya, J; Melnikov, P; Titov, S; Zybina, A | 1 |
| Caleffi-Ferracioli, KR; Cardoso, RF; de Lima Scodro, RB; de Souza, JVP; Murase, LS; Palomo, CT; Pavan, FR; Siqueira, VLD | 1 |
| Aslan, G; Ersoy, L; Özgür, D; Tezcan Ülger, S; Ülger, M | 1 |
| Adeel, A; Ahmad, A; Ahmad, I; Aslam, H; Mushtaq, F; Raza, SM; Saleem, S | 1 |
| McLaughlin, S | 1 |
2 review(s) available for verapamil and isoniazid
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
35 other study(ies) available for verapamil and isoniazid
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis.
Topics: Alpinia; Antibiotics, Antitubercular; Antitubercular Agents; Diarylheptanoids; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Plant Extracts; Seeds | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives.
Topics: Animals; Anti-Bacterial Agents; Chalcones; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Chromones; DNA Gyrase; DNA Topoisomerase IV; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Phloroglucinol; Structure-Activity Relationship; Topoisomerase II Inhibitors; Vero Cells | 2014 |
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis.
Topics: Antitubercular Agents; Cells, Cultured; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Drug Synergism; Extensively Drug-Resistant Tuberculosis; Humans; Macrophages; Microbial Sensitivity Tests; Mycobacterium smegmatis; Mycobacterium tuberculosis; Triazoles | 2016 |
Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercul
Topics: Adamantane; Antitubercular Agents; Carrier Proteins; Cell Line; Cell Survival; Computational Biology; Drug Design; Drug Resistance, Multiple, Bacterial; Ethylenediamines; Humans; Microbial Sensitivity Tests; Models, Molecular; Mycobacterium; Mycobacterium tuberculosis; Pharmaceutical Preparations; Piperazines; Pyrroles; Structure-Activity Relationship | 2016 |
Discovery of novel N-phenyl 1,4-dihydropyridines with a dual mode of antimycobacterial activity.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Discovery; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Niacin; Structure-Activity Relationship | 2016 |
Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Drug Resistance, Multiple, Bacterial; Drug Stability; Ethidium; Humans; Isoxazoles; Macrophages; Membrane Transport Proteins; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium tuberculosis; Thiazoles; Thioridazine; Verapamil | 2017 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
An antimycobacterial pleuromutilin analogue effective against dormant bacilli.
Topics: Administration, Oral; Animals; Antitubercular Agents; Area Under Curve; Biological Availability; Caco-2 Cells; Diterpenes; Female; Half-Life; Humans; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pleuromutilins; Polycyclic Compounds | 2018 |
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity.
Topics: Animals; Antiparasitic Agents; Antitubercular Agents; Caco-2 Cells; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Entamoeba histolytica; Giardia lamblia; Humans; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Nitroimidazoles; Structure-Activity Relationship | 2018 |
Nitroimidazopyrazinones with Oral Activity against Tuberculosis and Chagas Disease in Mouse Models of Infection.
Topics: Animals; Chagas Disease; Disease Models, Animal; Mice; Mycobacterium tuberculosis; Nitroimidazoles; Nitroreductases; Trypanosoma cruzi; Tuberculosis | 2022 |
Interaction with pyridoxal as a possible mechanism of hydralazine hypotension.
Topics: Anesthesia; Animals; Blood Pressure; Cinnarizine; Dose-Response Relationship, Drug; Hydralazine; Injections, Intraperitoneal; Isoniazid; Male; Pyridoxal; Pyridoxine; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil | 1990 |
Mycobacterium tuberculosis induces expression of P-glycoprotein in promonocytic U1 cells chronically infected with HIV type 1.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cell Line; Drug Resistance; Gene Expression; HIV-1; Humans; Isoniazid; Membrane Glycoproteins; Monocytes; Mycobacterium tuberculosis; Phagocytosis; Tumor Cells, Cultured; Verapamil; Virus Replication | 1994 |
Isoniazid accumulation in Mycobacterium smegmatis is modulated by proton motive force-driven and ATP-dependent extrusion systems.
Topics: Adenosine Triphosphate; Antitubercular Agents; Biological Transport, Active; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Diltiazem; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Ionophores; Isoniazid; Mycobacterium smegmatis; Nifedipine; Nigericin; Proton-Motive Force; Reserpine; Uncoupling Agents; Valinomycin; Vanadates; Verapamil | 1999 |
Isoniazid-induced transient high-level resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Calcium Channel Blockers; Drug Resistance, Bacterial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Peroxidases; Polymorphism, Restriction Fragment Length; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; Verapamil | 2002 |
2-bromoethylamine, a suicide inhibitor of semicarbazide-sensitive amine oxidase, increases hydralazine hypotension in rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Ethylamines; Heart Rate; Hydralazine; Isoniazid; Male; Rats; Rats, Wistar; Semicarbazides; Verapamil | 2005 |
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase; Chlorpromazine; DNA-Directed RNA Polymerases; Drug Resistance, Multiple, Bacterial; Gene Expression; Humans; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Rifampin; Thioridazine; Tuberculosis, Multidrug-Resistant; Verapamil | 2012 |
Role of the Mmr efflux pump in drug resistance in Mycobacterium tuberculosis.
Topics: Acriflavine; Anti-Infective Agents, Local; Antineoplastic Agents; Antitubercular Agents; Bacterial Proteins; Cetrimonium; Cetrimonium Compounds; Drug Resistance, Bacterial; Enzyme Inhibitors; Ethidium; Gene Knockout Techniques; Isoniazid; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Nitriles; Onium Compounds; Organophosphorus Compounds; Phenazines; Verapamil | 2013 |
New Verapamil Analogs Inhibit Intracellular Mycobacteria without Affecting the Functions of Mycobacterium-Specific T Cells.
Topics: Animals; Autophagy; Humans; Isoniazid; Leukocytes, Mononuclear; Macrophage Activation; Macrophages; Mice, Transgenic; Mycobacterium bovis; Mycobacterium tuberculosis; Rifampin; T-Lymphocytes; Verapamil | 2015 |
Nanoparticle-based delivery of carbamazepine: A promising approach for the treatment of refractory epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistant Epilepsy; Electrocorticography; Isoniazid; Lactic Acid; Male; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Verapamil | 2018 |
Isoniazid and verapamil modulatory activity and efflux pump gene expression in
Topics: Antitubercular Agents; Bacterial Proteins; Gene Expression; Humans; Isoniazid; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Tuberculosis, Multidrug-Resistant; Verapamil | 2020 |
[Investigation of Efflux Pump Genes in Resistant Mycobacterium tuberculosis Complex Clinical Isolates Exposed to First Line Antituberculosis Drugs and Verapamil Combination].
Topics: Antitubercular Agents; Bacterial Proteins; DNA, Complementary; Humans; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Rifampin; Tuberculosis; Tuberculosis, Multidrug-Resistant; Verapamil | 2023 |
Antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure.
Topics: Amikacin; Antitubercular Agents; Humans; Isoniazid; Linezolid; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Rifampin; Tuberculosis, Multidrug-Resistant; Verapamil | 2023 |
Evidence that polycystins are involved in Hydra cnidocyte discharge.
Topics: Animals; Calcium; Calcium Channel Blockers; Diterpenes; Epoxy Compounds; Gadolinium; Gene Expression; Glutathione; Hydra; Immunosuppressive Agents; Models, Molecular; Nematocyst; Neomycin; Phenanthrenes; Physical Stimulation; Predatory Behavior; Protein Domains; Protein Synthesis Inhibitors; Sense Organs; TRPP Cation Channels; Verapamil | 2017 |