verapamil has been researched along with fluorouracil in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (7.14) | 18.7374 |
| 1990's | 8 (14.29) | 18.2507 |
| 2000's | 18 (32.14) | 29.6817 |
| 2010's | 20 (35.71) | 24.3611 |
| 2020's | 6 (10.71) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ai, H; Gu, X; Lai, Y; Peng, H; Tang, X; Wang, G; Zhang, Y | 1 |
| Das, S; Das, U; Dimmock, JR; Gorecki, DK; Iwamoto, S; Kawase, M; Matsuta, T; Molnár, J; Sakagami, H; Serly, J; Umemura, N | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Deng, X; Huang, W; Qian, H; Qiu, Q; Wang, X; Yang, B | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Phillips, RL; Reinhart, AJ; Van Zant, G | 1 |
| Albertsson, M; Eskilsson, J | 1 |
| Hamada, H; Naito, M; Tsuruo, T | 1 |
| Campbell, J; Mayhew, E; Radel, S; Rustum, YM | 1 |
| Gamelli, RL; Morrow, M; Rosenthal, RA; Wait, RB | 1 |
| Hashimoto, K; Satoh, H | 1 |
| Brenner, RV; Buras, RR; Evans, SR; Nauta, RJ; Shabahang, M; Shchepotin, IB | 1 |
| Enigbokan, MA; Hubbard, C; Preston, J; Thompson, JO | 1 |
| Hasegawa, S; Koga, H; Kotoh, S; Kumazawa, J; Kuwano, M; Naito, S; Yokomizo, A | 1 |
| Delitheos, A; Giannakakou, P; Karavokyros, I; Tillgada, E | 1 |
| Müller, M; Roninson, I; Sarkadi, B; Szabó, K; Váradi, A; Welker, E | 1 |
| Huang, M; Liu, G | 1 |
| Ballinger, JR; Melo, T; Tannock, IF; Tunggal, JK | 1 |
| Ahn, BK; Chung, BS; Jeong, CS; Kang, CD; Kim, KW; Kim, SH; Lee, HJ; Yoo, SD | 1 |
| Belpomme, D; Benmiloud, M; Facchini, T; Frenay, M; Gauthier, S; Goudier, MJ; Gousset, C; Krakowski, I; Marié, FN; Netter-Pinon, G; Pujade-Lauraine, E; Sturtz, F | 1 |
| Appert, HE; Howard, JM; Iwamura, T; Liu, B; Staren, ED | 1 |
| Demin, LI; Minaev, II; Propp, AR; V'iushkov, DM; Zamorov, AG | 1 |
| Kakumoto, M; Kita, T; Kobayashi, H; Nakamura, T; Okamura, N; Okumura, K; Sakaeda, T; Takara, K; Yagami, T | 1 |
| Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B | 1 |
| Canevari, S; D'Ascenzo, S; Dolo, V; Millimaggi, D; Miotti, S; Pavan, A; Violini, S | 1 |
| Berman, B; Ramirez, CC; Villa, AM | 1 |
| Esser, JM; Esser, PJ; Hueber, A; Kociok, N; Lüke, C; Roters, S; Welsandt, G | 1 |
| Ambudkar, SV; Barnett, D; Bates, SE; Finley, EM; Fojo, T; Oldham, RK; Robey, RW; Shukla, S | 1 |
| Huang, G; Lartigau, E; Shi, D; Shi, G; Zhang, J | 1 |
| Hartman-Adams, H; Juckett, G | 1 |
| He, G; He, ZY; Hou, SX; Li, JM; Li, SZ; Luo, X; Luo, YF; Song, XR; Wei, YQ; Yang, L; Yu, S; Zheng, Y | 1 |
| Bao, L; Dash, S; Haque, A; Hazari, S; Jackson, K; Jetly, R; Moroz, K | 1 |
| Bhat, MK; Chaube, B; Pandey, V | 1 |
| Cai-Hong, Z; Fang, M; Jin-Hua, J; Li, H; Ning, W; Qing-Duan, W; Xiao-Juan, G; Yan, Z | 1 |
| Covell, DG | 1 |
| Cheng, BB; Fang, FF; Gu, W; Huang, F; Li, B; Liu, L | 1 |
| Chacon, A; Franca, K; Ledon, JA; Nouri, K; Savas, J | 1 |
| Alexandrescu, D; Fabi, S; Fitzpatrick, RE; Goldman, MP; Yeh, LC | 1 |
| Correia, A; Gärtner, F; Silva, D; Vale, N; Vilanova, M | 1 |
| Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR | 1 |
| Grebchenko, K; Teplyi, V | 1 |
| Li, Y; Wei, X; Zhuang, Z | 1 |
| Albalat, W; Khattab, F; Nabil, S | 1 |
| Aljaf, KAH; Azimi, S; Dariushnejad, H; Ghorbanzadeh, V; Pirzeh, L; Wasman, HM | 1 |
| da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN | 1 |
| Azimi, S; Dariushnejad, H; Esmaeil Lashgarian, H; Ghorbanzadeh, V; Moradipour, A; Pirzeh, L | 1 |
| Kundu, RV; Kwan, KR; Miller, CH; Pontes, D; Poondru, S; Walsh, LA; Wu, E | 1 |
8 review(s) available for verapamil and fluorouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Novel opportunities in the treatment and prevention of scarring.
Topics: Bleomycin; Botulinum Toxins, Type A; Celecoxib; Cicatrix; Fluorouracil; Humans; Immunosuppressive Agents; Laser Therapy; Neuromuscular Agents; Pyrazoles; Sulfonamides; Tacrolimus; Verapamil | 2004 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recurrence; Risk Factors; Time Factors; Tocopherols; Treatment Outcome; Verapamil; Wound Healing | 2009 |
Intralesional treatment for keloids and hypertrophic scars: a review.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Calcium Channel Blockers; Cicatrix, Hypertrophic; Combined Modality Therapy; Cryotherapy; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; Keloid; Verapamil | 2013 |
Comparative Results in Treatment of Keloids With Intralesional 5-FU/Kenalog, 5-FU/Verapamil, Enalapril Alone,Verapamil Alone, and Laser: A Case Report and Review of the Literature.
Topics: Adult; Drug Therapy, Combination; Enalapril; Fluorouracil; Humans; Injections, Intralesional; Keloid; Laser Therapy; Male; Treatment Outcome; Triamcinolone Acetonide; Verapamil | 2016 |
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesional; Keloid; Randomized Controlled Trials as Topic; Telangiectasis; Treatment Outcome; Triamcinolone Acetonide; Verapamil | 2021 |
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Dimethylpolysiloxanes; Erbium; Fluorouracil; Helium; Humans; Hypertrophy; Hypopigmentation; Keloid; Laser Therapy; Neodymium; Neon; Pain; Silicone Gels; Telangiectasis; Triamcinolone Acetonide; Verapamil; Wound Healing; Yttrium | 2022 |
Keloid treatments: an evidence-based systematic review of recent advances.
Topics: Adrenal Cortex Hormones; Fluorouracil; Humans; Keloid; Prospective Studies; Treatment Outcome; Verapamil | 2023 |
4 trial(s) available for verapamil and fluorouracil
| Article | Year |
|---|---|
Verapamil increases the survival of patients with anthracycline-resistant metastatic breast carcinoma.
Topics: Administration, Oral; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Calcium Channel Blockers; Cohort Studies; Disease-Free Survival; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Fluorouracil; Gastrointestinal Diseases; Humans; Life Tables; Middle Aged; Neoplasm Proteins; Prospective Studies; Survival Analysis; Treatment Outcome; Verapamil; Vindesine | 2000 |
[Prophylactics of acute pancreatitis in pancreatic-duodenal resection].
Topics: Acute Disease; Antimetabolites; Aprotinin; Drug Administration Schedule; Duodenum; Fluorouracil; Hormones; Humans; Intraoperative Care; Octreotide; Pancreas; Pancreatitis; Postoperative Care; Postoperative Complications; Serine Proteinase Inhibitors; Vasodilator Agents; Verapamil | 2002 |
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine | 2008 |
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperemia; Injections, Intralesional; Keloid; Male; Middle Aged; Prospective Studies; Treatment Outcome; Verapamil | 2019 |
44 other study(ies) available for verapamil and fluorouracil
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Synthesis and evaluation of nitric oxide-releasing DDB derivatives as potential Pgp-mediated MDR reversal agents in MCF-7/Adr cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Dicarboxylic Acids; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nitric Oxide | 2012 |
Dimeric 3,5-bis(benzylidene)-4-piperidones: a novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dimerization; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Piperidones | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Design, synthesis and biological evaluation of novel peptides with anti-cancer and drug resistance-reversing activities.
Topics: Animals; Antineoplastic Agents; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Erythrocytes; Hemolysis; Humans; MCF-7 Cells; Peptides; Rabbits; Structure-Activity Relationship; Tumor Cells, Cultured | 2015 |
Genetic control of murine hematopoietic stem cell pool sizes and cycling kinetics.
Topics: Animals; Antigens, CD; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Separation; Flow Cytometry; Fluorouracil; Hematopoiesis; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Kinetics; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Rhodamines; Stem Cell Factor; Verapamil; Wheat Germ Agglutinins | 1992 |
Failure of preventing 5-fluorouracil cardiotoxicity by prophylactic treatment with verapamil.
Topics: Adult; Aged; Arrhythmias, Cardiac; Chest Pain; Female; Fluorouracil; Heart; Humans; Male; Middle Aged; Verapamil | 1990 |
ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells.
Topics: Adenosine Triphosphate; Binding Sites; Biological Transport; Camptothecin; Cell Membrane; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Kinetics; Leukemia, Myeloid; Magnesium; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1988 |
Approaches to overcome in vivo anti-cancer drug resistance.
Topics: 3-Deazauridine; Animals; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Doxorubicin; Drug Resistance; Drug Synergism; Fluorouracil; Leucovorin; Leukemia L1210; Liposomes; Mice; Verapamil | 1986 |
Verapamil enhances antitumor activity without increasing myeloid toxicity.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells; Stem Cells; Verapamil; Vincristine | 1987 |
Effects of ftorafur and 5-fluorouracil on the canine sinoatrial node.
Topics: Aminophylline; Animals; Calcium; Dogs; Female; Fluorouracil; Heart Atria; Heart Rate; Male; Myocardial Contraction; Pindolol; Sinoatrial Node; Stimulation, Chemical; Tegafur; Verapamil | 1983 |
Antitumour activity of 5-fluorouracil, verapamil and hyperthermia against human gastric adenocarcinoma cell (AGS) in vitro.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Combined Modality Therapy; Female; Fluorouracil; Humans; Hyperthermia, Induced; Middle Aged; Stomach Neoplasms; Tumor Cells, Cultured; Verapamil | 1994 |
Characterization of and the influence of calcium channel blockers on the renal excretion of pyrimidine anticancer agents.
Topics: Absorption; Animals; Biological Transport; Blood Proteins; Calcium Channels; Carrier Proteins; Chromatography, High Pressure Liquid; Diltiazem; Floxuridine; Fluorouracil; Inulin; Kidney; Male; Membrane Proteins; Mice; Monosaccharide Transport Proteins; Nucleoside Transport Proteins; Verapamil | 1994 |
Non-P-glycoprotein-mediated atypical multidrug resistance in a human bladder cancer cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Transitional Cell; Cisplatin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Fluorouracil; Humans; Mitomycin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Selection, Genetic; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Verapamil; Vinca Alkaloids | 1995 |
Effect of calcium channel blockers on the action of various antitumour agents in the yeast Saccharomyces cerevisiae.
Topics: Antineoplastic Agents; Calcium Channel Blockers; Cell Survival; Diltiazem; Doxorubicin; Fluorouracil; Saccharomyces cerevisiae; Verapamil | 1996 |
Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cyclosporine; Enzyme Inhibitors; Ethylmaleimide; Fluoresceins; Fluorouracil; Humans; Protein Binding; Recombinant Proteins; Verapamil | 1998 |
The study of innate drug resistance of human hepatocellular carcinoma Bel7402 cell line.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bisbenzimidazole; Carcinoma, Hepatocellular; DNA; DNA Fragmentation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorouracil; Humans; Immunohistochemistry; KB Cells; Liver Neoplasms; Tumor Cells, Cultured; Verapamil; Vincristine | 1999 |
The influence of expression of P-glycoprotein on the penetration of anticancer drugs through multicellular layers.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carbon Radioisotopes; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Mice; Models, Biological; Radiopharmaceuticals; Sarcoma, Experimental; Sucrose; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured; Verapamil | 2000 |
Downregulation of JNK/SAPK activity is associated with the cross-resistance to P-glycoprotein-unrelated drugs in multidrug-resistant FM3A/M cells overexpressing P-glycoprotein.
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bleomycin; Cell Survival; Drug Resistance, Multiple; Female; Fluorouracil; Genes, MDR; JNK Mitogen-Activated Protein Kinases; Mammary Neoplasms, Experimental; Mice; Mitogen-Activated Protein Kinases; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 2000 |
Mechanisms of taxotere-related drug resistance in pancreatic carcinoma.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Paclitaxel; Pancreatic Neoplasms; Rhodamine 123; RNA, Messenger; Taxoids; Tubulin; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 2001 |
Effects of carvedilol on MDR1-mediated multidrug resistance: comparison with verapamil.
Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Carbazoles; Carvedilol; Cell Division; Cell Line; Daunorubicin; Digoxin; DNA, Complementary; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial Cells; Fluorouracil; HeLa Cells; Humans; Inhibitory Concentration 50; Kidney; Paclitaxel; Propanolamines; Swine; Transfection; Verapamil; Vinblastine | 2003 |
Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Atrial Fibrillation; Captopril; Chest Pain; Colorectal Neoplasms; Coronary Angiography; Digoxin; Disease Management; Echocardiography; Electrocardiography; Fluorouracil; Humans; Laryngeal Neoplasms; Middle Aged; Myocardial Infarction; Nitrates; Verapamil | 2003 |
Induction of a multifactorial resistance phenotype by high paclitaxel selective pressure in a human ovarian carcinoma cell line.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorouracil; Humans; Inhibitory Concentration 50; Methotrexate; Mitochondrial Proteins; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Phenotype; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Time Factors; Tubulin; Verapamil; Vinblastine | 2004 |
Mitomycin C induces multidrug resistance in glaucoma surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Child; Connective Tissue Cells; Drug Resistance, Multiple; Female; Fibroblasts; Flow Cytometry; Fluorouracil; Glaucoma, Open-Angle; Humans; Immunoenzyme Techniques; Male; Middle Aged; Mitomycin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trabeculectomy; Verapamil | 2008 |
Chemosensitivity of radioresistant cells in the multicellular spheroids of A549 lung adenocarcinoma.
Topics: Adenocarcinoma; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Calcium Channel Blockers; Cell Proliferation; Cisplatin; Dose Fractionation, Radiation; Doxorubicin; Drug Resistance, Neoplasm; Fluorouracil; Humans; Lung Neoplasms; Mitomycin; Radiation Tolerance; Spheroids, Cellular; Tumor Cells, Cultured; Verapamil; Vindesine; X-Rays | 2009 |
Development of PLGA nanoparticles simultaneously loaded with vincristine and verapamil for treatment of hepatocellular carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Fluorouracil; Humans; Lactic Acid; Liver Neoplasms; Nanoparticles; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetrazolium Salts; Thiazoles; Verapamil; Vincristine | 2010 |
Increased expression of P-glycoprotein is associated with doxorubicin chemoresistance in the metastatic 4T1 breast cancer model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line, Tumor; Cell Proliferation; Cell Separation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorouracil; G2 Phase; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mitosis; Neoplasm Metastasis; Survival Analysis; Verapamil | 2011 |
Hyperglycemia regulates MDR-1, drug accumulation and ROS levels causing increased toxicity of carboplatin and 5-fluorouracil in MCF-7 cells.
Topics: Acetylcysteine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carboplatin; Cell Line, Tumor; Female; Fluorouracil; Glucose; Humans; Hyperglycemia; Inhibitory Concentration 50; NF-kappa B; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Verapamil | 2011 |
Using rhodamine 123 accumulation in CD8 cells as a surrogate indicator to study the P-glycoprotein modulating effect of cepharanthine hydrochloride in vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Humans; Indicators and Reagents; Liver Neoplasms; Mice; Rhodamine 123; Tumor Cells, Cultured; Verapamil; Xenograft Model Antitumor Assays | 2011 |
Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.
Topics: Algorithms; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cluster Analysis; Colchicine; Computational Biology; Cyclin-Dependent Kinases; Dasatinib; Databases, Genetic; Fluorouracil; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasms; Oligonucleotide Array Sequence Analysis; Paclitaxel; Pimozide; Purines; Pyrimidines; Terfenadine; Thiazoles; Tubulin Modulators; Verapamil | 2012 |
Reversal effect of bufalin on multidrug resistance in human hepatocellular carcinoma BEL-7402/5-FU cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; bcl-X Protein; Bufanolides; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Survival; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; G1 Phase Cell Cycle Checkpoints; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Thymidylate Synthase; Verapamil | 2014 |
Study of New Therapeutic Strategies to Combat Breast Cancer Using Drug Combinations.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Female; Fluorouracil; Humans; Itraconazole; MCF-7 Cells; Verapamil | 2018 |
The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Dose Fractionation, Radiation; Fluorouracil; Humans; Immunohistochemistry; Keloid; Laser Therapy; Lasers, Gas; Transforming Growth Factor beta1; Treatment Outcome; Verapamil | 2019 |
Assessment of various intralesional injections in keloid: comparative analysis.
Topics: Fluorouracil; Humans; Injections, Intralesional; Keloid; Treatment Outcome; Triamcinolone Acetonide; Verapamil | 2022 |
Carvacrol Enhance Apoptotic Effect of 5-FU on MCF-7 Cell Line via inhibiting P-glycoprotein: An In-silco and In-vitro Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cymenes; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; MCF-7 Cells; Verapamil | 2022 |
5-FU and the dietary flavonoid carvacrol: a synergistic combination that induces apoptosis in MCF-7 breast cancer cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cymenes; Drug Synergism; Female; Flavonoids; Fluorouracil; Humans; MCF-7 Cells; Verapamil | 2022 |