verapamil has been researched along with flumazenil in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Little, HJ | 1 |
| Chugun, A; Futamura, K; Hara, Y; Kobayashi, H; Kondo, H; Nishino, T; Ooshiro, S; Temma, K | 1 |
| Hendrikse, NH; Ishiwata, K; Kawamura, K; Yanai, K | 1 |
| Bispo-da-Silva, LB; da Silveira, NS; de Oliveira-Silva, GL; Lamanes, Bde F; Prado, LC | 1 |
| Asselin, MC; Boellaard, R; Froklage, FE; Huisman, MC; Lammertsma, AA; Mansor, SM; Schuit, RC; van Assema, DM; van Berckel, BN; van Velden, FH; Wang, S | 1 |
| Sossi, V; Walker, MD | 1 |
2 review(s) available for verapamil and flumazenil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The benzodiazepines: anxiolytic and withdrawal effects.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Disease Models, Animal; Ethanol; Flumazenil; Humans; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome; Verapamil | 1991 |
18 other study(ies) available for verapamil and flumazenil
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Negative inotropic effect of diazepam in isolated guinea pig heart.
Topics: Adjuvants, Anesthesia; Animals; Anti-Arrhythmia Agents; Calcium Channels; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Guinea Pigs; Heart; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Myocardial Contraction; Patch-Clamp Techniques; Verapamil | 2001 |
In vivo evaluation of P-glycoprotein modulation of 8 PET radioligands used clinically.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cyclosporine; Donepezil; Flumazenil; Indans; Ligands; Male; Mice; Piperidines; Positron-Emission Tomography; Radioisotopes; Sensory Receptor Cells; Verapamil; Xanthines | 2007 |
The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone.
Topics: Animals; Anti-Anxiety Agents; Central Nervous System Stimulants; Choice Behavior; Conditioning, Psychological; Cyclohexane Monoterpenes; Diltiazem; Drug Interactions; Flumazenil; Grooming; Haloperidol; Hand Strength; Male; Maze Learning; Menthol; Mice; Monoterpenes; Motor Activity; Picrotoxin; Reinforcement, Psychology; Rotarod Performance Test; Verapamil | 2014 |
Comparison of HRRT and HR+ scanners for quantitative (R)-[11C]verapamil, [11C]raclopride and [11C]flumazenil brain studies.
Topics: Brain; Carbon Radioisotopes; Case-Control Studies; Flumazenil; GABA Modulators; Healthy Volunteers; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Positron-Emission Tomography; Raclopride; Radioisotopes; Reference Values; Reproducibility of Results; Tissue Distribution; Tomography Scanners, X-Ray Computed; Tomography, X-Ray Computed; Vasodilator Agents; Verapamil | 2015 |
Commentary: an eye on PET quantification.
Topics: Brain; Carbon Radioisotopes; Flumazenil; Humans; Positron-Emission Tomography; Tomography Scanners, X-Ray Computed; Tomography, X-Ray Computed; Verapamil | 2015 |